Gating competence of constitutively open CLC-0 mutants revealed by the interaction with a small organic inhibitor

Journal of General Physiology

Volumn 122, Issue 3, 2003, Pages 295-306

  Traverso, Sonia ^a   Elia, Laura ^a   Pusch, Michael ^a  

^a CNR   (Italy)

Author keywords

Chloride channel; Chloride dependence; CLC; Clofibric acid; Mutation

Indexed keywords

4 CHLOROPHENOXYACETIC ACID; ALANINE; ANION; ASPARTIC ACID; CHLORIDE CHANNEL; GLUTAMIC ACID; LYSINE; SERINE;

AMINO ACID SUBSTITUTION; ARTICLE; BINDING AFFINITY; CHANNEL GATING; CONFORMATION; ELECTRIC POTENTIAL; MEMBRANE PERMEABILITY; MODEL; MUTAGENESIS; MUTANT; MUTATION; PROTEIN STRUCTURE; STEADY STATE; WILD TYPE;

2,4-DICHLOROPHENOXYACETIC ACID; ALANINE; ANIMALS; BINDING, COMPETITIVE; CHLORIDE CHANNELS; GLUTAMIC ACID; HOMEOSTASIS; ION CHANNEL GATING; KINETICS; LINEAR MODELS; MODELS, BIOLOGICAL; MUTATION; OOCYTES; SERINE; TORPEDO; XENOPUS;

EID: 0141513678     PISSN: 00221295     EISSN: None     Source Type: Journal    
DOI: 10.1085/jgp.200308784     Document Type: Article

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