Protease-activated receptor-1 (PAR1) acts via a novel Gα 13-dishevelled axis to stabilize β-catenin levels

Journal of Biological Chemistry

Volumn 285, Issue 20, 2010, Pages 15137-15148

  Turm, Hagit ^a   Maoz, Myriam ^a   Katz, Vered ^a   Yin, Yong Jun ^a   Offermanns, Steffan ^b   Bar Shavit, Rachel ^a  

^a HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

^b MAX PLANCK INSTITUTE FOR HEART AND LUNG RESEARCH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AGE-MATCHED CONTROLS; ARRESTINS; DOMINANT NEGATIVE; LOW DENSITY LIPOPROTEINS; MAMMARY TISSUE; PROTEASE-ACTIVATED RECEPTOR-1; SMALL INTERFERING RNA; TRANSCRIPTION ACTIVITY; TRANSGENICS; WNT SIGNALING;

PHOSPHORYLATION; PROTEINS; RNA; SIGNALING; TRANSCRIPTION;

STABILIZATION;

BETA ARRESTIN 2; BETA CATENIN; DISHEVELLED PROTEIN; FRIZZLED PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 5; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 6; LYMPHOID ENHANCER FACTOR; MATRIGEL; PROTEIN GALPHA12; PROTEIN GALPHA13; PROTEINASE ACTIVATED RECEPTOR 1; SECRETED FRIZZLED RELATED PROTEIN 2; SECRETED FRIZZLED RELATED PROTEIN 5; SMALL INTERFERING RNA; T LYMPHOCYTE FACTOR; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; WNT PROTEIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BREAST; CELL INVASION; CELL STRAIN HCT116; CELL STRAIN HEK293; CELL STRAIN HT29; CONTROLLED STUDY; GENE SILENCING; HUMAN; HUMAN CELL; IMMUNOHISTOLOGY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; ARRESTINS; BETA CATENIN; CELL LINE; GENE SILENCING; GTP-BINDING PROTEIN ALPHA SUBUNITS, G12-G13; HUMANS; IMMUNOPRECIPITATION; MICE; MICE, TRANSGENIC; PHOSPHOPROTEINS; RECEPTOR, PAR-1;

MUS MUSCULUS;

EID: 77952047728     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.072843     Document Type: Article

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