Axin contains three separable domains that confer intramolecular, homodimeric, and heterodimeric interactions involved in distinct functions

Journal of Biological Chemistry

Volumn 280, Issue 6, 2005, Pages 5054-5060

  Luo, Wen ^a   Zou, Haiying ^a   Jin, Lihua ^a   Lin, Shuyong ^b   Li, Qinxi ^a   Ye, Zhiyun ^a   Rui, Hongliang ^b   Lin, Sheng Cai ^a,b  

^a XIAMEN UNIVERSITY   (China)

^b HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

DIMERS; GENETIC ENGINEERING; MOLECULAR BIOLOGY; MOLECULAR STRUCTURE;

HOMODIMERIZATION; MUTANTS; MUTATION; OLIGOMERIZATION;

PROTEINS;

AXIN; BETA CATENIN; CCD1 PROTEIN; JANUS KINASE; MUTANT PROTEIN; PROTEIN; STRUCTURAL PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CARBOXY TERMINAL SEQUENCE; DIMERIZATION; HUMAN; HUMAN CELL; OLIGOMERIZATION; POINT MUTATION; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN MODIFICATION;

BETA CATENIN; BLOTTING, WESTERN; CELL LINE; CYTOSKELETAL PROTEINS; DIMERIZATION; GENE DELETION; GENES, REPORTER; HUMANS; IMMUNOPRECIPITATION; LUCIFERASES; MODELS, MOLECULAR; MUTATION; PLASMIDS; POINT MUTATION; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; REPRESSOR PROTEINS; TRANS-ACTIVATORS; TRANSFECTION;

EID: 14244255009     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M412340200     Document Type: Article

References (32)

1. Zeng, L., Fagotto, F., Zhang, T., Hsu, W., Vasicek, T. J., Perry, W. L., III, Lee, J. J., Tilghman, S. M., Gumbiner, B. M., and Costantini, F. (1997) Cell 90, 181-192
2. Logan, C. Y., and Nusse, R. (2004) Annu. Rev. Cell Dev. Biol. 20, 781-810
3. Polakis, P. (2000) Genes Dev. 14, 1837-1851
4. Luo, W., and Lin, S. C. (2004) Neurosignals 13, 99-113
5. Tolwinski, N. S., and Wieschaus, E. (2004) Trends Genet. 20, 177-181
6. Kishida, S., Yamamoto, H., Hino, S., Ikeda, M., Kishida, M., and Kikuchi, A. (1999) Mol. Cell. Biol. 19, 4414-4422
7. Ikeda, S., Kishida, S., Yamamoto, H., Murai, H., Koyama, S., and Kikuchi, A. (1998) EMBO J. 17, 1371-1384
8. Cadigan, K. M., and Nusse, R. (1997) Genes Dev. 11, 3286-3305
9. Dale, T. C. (1998) Biochem. J. 329, 209-223
10. Yanagawa, S., van Leeuwen, F., Wodarz, A., Klingensmith, J., and Nusse, R. (1995) Genes Dev. 9, 1087-1097
11. Yanagawa, S., Lee, J., Haruna, T., Oda, H., Uemura, T., Takeichi, M., and Ishimoto, A. (1997) J. Biol. Chem. 272, 25243-25251
12. Li, L., Yuan, H., Weaver, C. D., Mao, J., Farr, G. H., Sussman, D. J., Jonkers, J., Kimelman, D., and Wu, D. (1999) EMBO J. 18, 4233-4240
13. Hino, S., Michiue, T., Asashima, M., and Kikuchi, A. (2003) J. Biol. Chem. 278, 14066-14073
14. Shiomi, K., Uchida, H., Keino-Masu, K., and Masu, M. (2003) Curr. Biol. 13, 73-77
15. Wong, C. K., Luo, W., Deng, Y., Zou, H., Ye, Z., and Lin, S. C. (2004) J. Biol. Chem. 279, 39366-39373
16. Ciani, L., Krylova, O., Smalley, M. J., Dale, T. C., and Salinas, P. C. (2004) J. Cell Biol. 164, 243-253
17. Zhang, Y., Neo, S. Y., Han, J., and Lin, S. C. (2000) J. Biol. Chem. 275, 25008-25014
18. Zhang, Y., Neo, S. Y., Wang, X., Han, J., and Lin, S. C. (1999) J. Biol. Chem. 274, 35247-35254
19. Luo, W., Ng, W. W., Jin, L. H., Ye, Z., Han, J., and Lin, S. C. (2003) J. Biol. Chem. 278, 37451-37458
20. Zhang, Y., Qiu, W. J., Liu, D. X., Neo, S. Y., He, X., and Lin, S. C. (2001) J. Biol. Chem. 276, 32152-32159
21. Cliffe, A., Hamada, F., and Bienz, M. (2003) Curr. Biol. 13, 960-966
22. Julius, M. A., Schelbert, B., Hsu, W., Fitzpatrick, E., Jho, E., Fagotto, F., Costantini, F., and Kitajewski, J. (2000) Biochem. Biophys. Res. Commun. 276, 1162-1169
23. Hsu, W., Zeng, L., and Costantini, F. (1999) J. Biol. Chem. 274, 3439-3445
24. Spink, K. E., Polakis, P., and Weis, W. I. (2000) EMBO J. 19, 2270-2279
25. Dajani, R., Fraser, E., Roe, S. M., Yeo, M., Good, V. M., Thompson, V., Dale, T. C., and Pearl, L. H. (2003) EMBO J. 22, 494-501
26. Jin, L. H., Shao, Q. J., Luo, W., Ye, Z. Y., Li, Q., and Lin, S. C. (2003) Int. J. Cancer 107, 696-699
27. Rui, Y. N., Xu, Z., Lin, S. Y., Li, Q., Rui, H., Luo, W., Zhou, H.-M., Cheung, P.-Y., Wu, Z., Ye, Z., Li, P., Han, J., and Lin, S.-C. (2004) EMBO J. 23, 4583-4594
28. Sakanaka, C., and Williams, L. T. (1999) J. Biol. Chem. 274, 14090-14093
29. Jones, W. M., and Bejsovec, A. (2003) Curr. Biol. 13, R479-R481
30. Capelluto, D. G. S., Kutateladze, T. G., Habas, R., Finkielstein, C. V., He, X., and Overduin, M. (2002) Nature 419, 726-729
31. Vasicek, T. J., Zeng, L., Guan, X. J., Zhang, T., Costantini, F., and Tilghman, S. M. (1997) Genetics. 147, 777-786
32. Zhang, Y., Qiu, W. J., Chan, S. C., Han, J., He, X., and Lin, S. C. (2002) J. Biol. Chem. 277, 17706-17712