Methylenedioxymethamphetamine inhibits mitochondrial complex i activity in mice: A possible mechanism underlying neurotoxicity

British Journal of Pharmacology

Volumn 160, Issue 2, 2010, Pages 233-245

  Puerta, Elena ^a   Hervias, Isabel ^a   Goñi Allo, Beatriz ^a   Zhang, Steven F ^b   Jordán, Joaquín ^c   Starkov, Anatoly A ^b   Aguirre, Norberto ^a  

^a UNIVERSITY OF NAVARRA   (Spain)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

^c UNIVERSITY OF CASTILLA LA MANCHA   (Spain)

Author keywords

Complex I; Dopamine; Lipoic acid; MDMA; Mitochondria; Oxidative stress

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; 3,4 METHYLENEDIOXYMETHAMPHETAMINE; ACONITATE HYDRATASE; BUTHIONINE SULFOXIMINE; DOPAMINE; GLUTATHIONE; N(G) NITROARGININE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); SUPEROXIDE; THIOCTIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORPUS STRIATUM; ENZYME INHIBITION; MALE; MOLECULAR MECHANICS; MOUSE; NEUROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL;

ANIMALS; ANTIOXIDANTS; CORPUS STRIATUM; DOPAMINE; ELECTRON TRANSPORT COMPLEX I; FREE RADICALS; HALLUCINOGENS; MALE; MICE; MITOCHONDRIA; N-METHYL-3,4-METHYLENEDIOXYAMPHETAMINE; NEUROTOXICITY SYNDROMES; OXIDATIVE STRESS; THIOCTIC ACID;

EID: 77951679086     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2010.00663.x     Document Type: Article

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