Persistent MDMA-induced dopaminergic neurotoxicity in the striatum and substantia nigra of mice

Journal of Neurochemistry

Volumn 107, Issue 4, 2008, Pages 1102-1112

  Granado, Noelia ^a,b   O'Shea, Esther ^c   Bove, Jordi ^b,d,e   Vila, Miquel ^b,d,e   Colado, Ma Isabel ^c   Moratalla, Rosario ^a,b  

^a INSTITUTO CAJAL   (Spain)

^b INSTITUTO DE SALUD CARLOS III   (Spain)

^c UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^d HOSPITAL UNIVERSITARI VALL D HEBRON   (Spain)

^e INSTITUCIÓ CATALANA DE RECERCA I ESTUDIS AVANÇATS ICREA   (Spain)

Author keywords

Dopamine; Dopamine transporter; Ecstasy; Neurodegeneration; Parkinson's disease; Tyrosine hydroxylase

Indexed keywords

3,4 METHYLENEDIOXYMETHAMPHETAMINE; CD11B ANTIGEN; DOPAMINE TRANSPORTER; GLIAL FIBRILLARY ACIDIC PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; TYROSINE 3 MONOOXYGENASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CORPUS STRIATUM; DOPAMINERGIC NERVE CELL; IMMUNOREACTIVITY; MALE; MESOLIMBIC DOPAMINERGIC SYSTEM; MOUSE; NEUROTOXICITY; NONHUMAN; NUCLEUS ACCUMBENS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SUBSTANTIA NIGRA;

ANIMALS; CELL DEATH; CORPUS STRIATUM; DOPAMINE; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEVER; GLIAL FIBRILLARY ACIDIC PROTEIN; MACROPHAGE-1 ANTIGEN; MALE; MICE; MICE, INBRED C57BL; N-METHYL-3,4-METHYLENEDIOXYAMPHETAMINE; NEURONS; NEUROTOXINS; NITRIC OXIDE SYNTHASE; STEREOTAXIC TECHNIQUES; SUBSTANTIA NIGRA; TIME FACTORS; TYROSINE 3-MONOOXYGENASE;

MUS;

EID: 54349116574     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2008.05705.x     Document Type: Article

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