-
1
-
-
0037174635
-
Treatment of ischemic brain damage by perturbing NMDA receptor-PSD-95 protein interactions
-
DOI 10.1126/science.1072873
-
Aarts M, Liu Y, Liu L, Besshoh S, Arundine M, Gurd JW, Wang YT, Salter MW, Tymianski M. 2002. Treatment of ischemic brain damage by perturbing NMDA receptor- PSD-95 protein interactions. Science 298:846-850. (Pubitemid 35231541)
-
(2002)
Science
, vol.298
, Issue.5594
, pp. 846-850
-
-
Aarts, M.1
Liu, Y.2
Liu, L.3
Besshoh, S.4
Arundine, M.5
Gurd, J.W.6
Wang, Y.-T.7
Salter, M.W.8
Tymianski, M.9
-
3
-
-
0034857627
-
TAT-mediated protein transduction into mammalian cells
-
DOI 10.1006/meth.2001.1186
-
Becker-Hapak M, McAllister SS, Dowdy SF. 2001. TAT-mediated protein transduction into mammalian cells. Methods 24:247-256. (Pubitemid 32846431)
-
(2001)
Methods
, vol.24
, Issue.3
, pp. 247-256
-
-
Becker-Hapak, M.1
McAllister, S.S.2
Dowdy, S.F.3
-
4
-
-
31344439465
-
The kinetics and tissue distribution of protein transduction in mice
-
DOI 10.1016/j.ejps.2005.10.011, PII S092809870500309X
-
Cai SR, Xu G, Becker-Hapak M, Ma M, Dowdy SF, McLeod HL. 2006. The kinetics and tissue distribution of protein transduction in mice. Eur J Pharm Sci 27:311-319. (Pubitemid 43143256)
-
(2006)
European Journal of Pharmaceutical Sciences
, vol.27
, Issue.4
, pp. 311-319
-
-
Cai, S.-R.1
Xu, G.2
Becker-Hapak, M.3
Ma, M.4
Dowdy, S.F.5
McLeod, H.L.6
-
5
-
-
0036663014
-
In vivo delivery of a Bcl-xL fusion protein containing the TAT protein transduction domain protects against ischemic brain injury and neuronal apoptosis
-
Cao G, Pei W, Ge H, Liang Q, Luo Y, Sharp FR, Lu A, Ran R, Graham SH, Chen J. 2002. In vivo delivery of a Bcl-xL fusion protein containing the TAT protein transduction domain protects against ischemic brain injury and neuronal apoptosis. J Neurosci 22:5423-5431.
-
(2002)
J Neurosci
, vol.22
, pp. 5423-5431
-
-
Cao, G.1
Pei, W.2
Ge, H.3
Liang, Q.4
Luo, Y.5
Sharp, F.R.6
Lu, A.7
Ran, R.8
Graham, S.H.9
Chen, J.10
-
6
-
-
0033600913
-
PSD-95 assembles a ternary complex with the N-methyl-D-aspartic acid receptor and a bivalent neuronal NO synthase PDZ domain
-
Christopherson KS, Hillier BJ, Lim WA, Bredt DS. 1999. PSD-95 assembles a ternary complex with the N-methyl-D-aspartic acid receptor and a bivalent neuronal NO synthase PDZ domain. J Biol Chem 274:27467-27473. (Pubitemid 129527789)
-
(1999)
Journal of Biological Chemistry
, vol.274
, Issue.39
, pp. 27467-27473
-
-
Christopherson, K.S.1
Hillier, B.J.2
Wendell A, L.3
Bredt, D.S.4
-
7
-
-
40849124044
-
Recent advances in cell-penetrating, non-peptide molecular carriers
-
DOI 10.1016/j.ijpharm.2007.08.016, PII S0378517307006977
-
Chung SK, Maiti KK, Lee WS. 2008. Recent advances in cell-penetrating, non-peptide molecular carriers. Int J Pharm 354:16-22. (Pubitemid 351400324)
-
(2008)
International Journal of Pharmaceutics
, vol.354
, Issue.1-2
, pp. 16-22
-
-
Chung, S.-K.1
Maiti, K.K.2
Lee, W.S.3
-
8
-
-
0041816277
-
Antennapedia and HIV transactivator of transcription (TAT) "protein transduction domains" promote endocytosis of high molecular weight cargo upon binding to cell surface glycosaminoglycans
-
Console S, Marty C, Garcia-Echeverria C, Schwendener R, Ballmer-Hofer K. 2003. Antennapedia and HIV transactivator of transcription (TAT) "protein transduction domains" promote endocytosis of high molecular weight cargo upon binding to cell surface glycosaminoglycans. J Biol Chem 278:35109-35114.
-
(2003)
J Biol Chem
, vol.278
, pp. 35109-35114
-
-
Console, S.1
Marty, C.2
Garcia-Echeverria, C.3
Schwendener, R.4
Ballmer-Hofer, K.5
-
10
-
-
0038730828
-
A novel TAT-mitochondrial signal sequence fusion protein is processed, stays in mitochondria, and crosses the placenta
-
Del GV, Payne RM. 2003. A novel TAT-mitochondrial signal sequence fusion protein is processed, stays in mitochondria, and crosses the placenta. Mol Ther 7:720-730.
-
(2003)
Mol Ther
, vol.7
, pp. 720-730
-
-
Del, G.V.1
Payne, R.M.2
-
11
-
-
0038325747
-
Protein transduction technology offers novel therapeutic approach for brain ischemia
-
DOI 10.1016/S0165-6147(03)00074-9
-
Denicourt C, Dowdy SF. 2003. Protein transduction technology offers novel therapeutic approach for brain ischemia. Trends Pharmacol Sci 24:216-218. (Pubitemid 36588866)
-
(2003)
Trends in Pharmacological Sciences
, vol.24
, Issue.5
, pp. 216-218
-
-
Denicourt, C.1
Dowdy, S.F.2
-
12
-
-
0024262589
-
Cellular uptake of the tat protein from human immunodeficiency virus
-
Frankel AD, Pabo CO. 1988. Cellular uptake of the tat protein from human immunodeficiency virus. Cell 55:1189-1193.
-
(1988)
Cell
, vol.55
, pp. 1189-1193
-
-
Frankel, A.D.1
Pabo, C.O.2
-
13
-
-
33845209963
-
+ exchanger inhibitors on subcellular localisation of endocytic organelles and intracellular dynamics of protein transduction domains HIV-TAT peptide and octaarginine
-
+ exchanger inhibitors on subcellular localisation of endocytic organelles and intracellular dynamics of protein transduction domains HIV-TAT peptide and octaarginine. J Control Release 116:247-254.
-
(2006)
J Control Release
, vol.116
, pp. 247-254
-
-
Fretz, M.1
Jin, J.2
Conibere, R.3
Penning, N.A.4
Al-Taei, S.5
Storm, G.6
Futaki, S.7
Takeuchi, T.8
Nakase, I.9
Jones, A.T.10
-
14
-
-
1542327642
-
Pathway for Polyarginine Entry into Mammalian Cells
-
DOI 10.1021/bi035933x
-
Fuchs SM, Raines RT. 2004. Pathway for polyarginine entry into mammalian cells. Biochemistry 43:2438-2444. (Pubitemid 38327839)
-
(2004)
Biochemistry
, vol.43
, Issue.9
, pp. 2438-2444
-
-
Fuchs, S.M.1
Raines, R.T.2
-
15
-
-
33646236541
-
Oligoarginine vectors for intracellular delivery: Design and cellular-uptake mechanisms
-
Futaki S. 2006. Oligoarginine vectors for intracellular delivery: design and cellular-uptake mechanisms. Biopolymers 84:241-249.
-
(2006)
Biopolymers
, vol.84
, pp. 241-249
-
-
Futaki, S.1
-
16
-
-
0035937124
-
Arginine-rich peptides. An abundant source of membrane-permeable peptides having potential as carriers for intracellular protein delivery
-
DOI 10.1074/jbc.M007540200
-
Futaki S, Suzuki T, Ohashi W, Yagami T, Tanaka S, Ueda K, Sugiura Y. 2001. Arginine-rich peptides. An abundant source of membrane-permeable peptides having potential as carriers for intracellular protein delivery. J Biol Chem 276:5836-5840. (Pubitemid 37385738)
-
(2001)
Journal of Biological Chemistry
, vol.276
, Issue.8
, pp. 5836-5840
-
-
Futaki, S.1
Suzuki, T.2
Ohashi, W.3
Yagami, T.4
Tanaka, S.5
Ueda, K.6
Sugiura, Y.7
-
17
-
-
0038048993
-
Structural variety of membrane permeable peptides
-
DOI 10.2174/1389203033487261
-
Futaki S, Goto S, Suzuki T, Nakase I, Sugiura Y. 2003. Structural variety of membrane permeable peptides. Curr Protein Pept Sci 4:87-96. (Pubitemid 36834008)
-
(2003)
Current Protein and Peptide Science
, vol.4
, Issue.2
, pp. 87-96
-
-
Futaki, S.1
Goto, S.2
Suzuki, T.3
Nakase, I.4
Sugiura, Y.5
-
18
-
-
34548183102
-
Arginine-rich peptides and their internalization mechanisms
-
Futaki S, Nakase I, Tadokoro A, Takeuchi T, Jones AT. 2007. Arginine-rich peptides and their internalization mechanisms. Biochem Soc Trans 35:784-787. (Pubitemid 47310368)
-
(2007)
Biochemical Society Transactions
, vol.35
, Issue.4
, pp. 784-787
-
-
Futaki, S.1
Nakase, I.2
Tadokoro, A.3
Takeuchi, T.4
Jones, A.T.5
-
19
-
-
0034677145
-
Knock down of spinal NMDA receptors reduces NMDA and formalin evoked behaviors in rat
-
Garry MG, Malik S, Yu J, Davis MA, Yang J. 2000. Knock down of spinal NMDA receptors reduces NMDA and formalin evoked behaviors in rat. NeuroReport 11:49-55. (Pubitemid 30053388)
-
(2000)
NeuroReport
, vol.11
, Issue.1
, pp. 49-55
-
-
Garry, M.G.1
Malik, S.2
Yu, J.3
Davis, M.A.4
Yang, J.5
-
20
-
-
14044270161
-
Binding of oligoarginine to membrane lipids and heparan sulfate: Structural and thermodynamic characterization of a cell-penetrating peptide
-
DOI 10.1021/bi048046i
-
Goncalves E, Kitas E, Seelig J. 2005. Binding of oligoarginine to membrane lipids and heparan sulfate: structural and thermodynamic characterization of a cell-penetrating peptide. Biochemistry 44:2692-2702. (Pubitemid 40279574)
-
(2005)
Biochemistry
, vol.44
, Issue.7
, pp. 2692-2702
-
-
Goncalves, E.1
Kitas, E.2
Seelig, J.3
-
21
-
-
33749656235
-
Molecular transporters: Synthesis of oligoguanidinium transporters and their application to drug delivery and real-time imaging
-
Goun EA, Pillow TH, Jones LR, Rothbard JB, Wender PA. 2006. Molecular transporters: synthesis of oligoguanidinium transporters and their application to drug delivery and real-time imaging. Chembiochem 7:1497-1515.
-
(2006)
Chembiochem
, vol.7
, pp. 1497-1515
-
-
Goun, E.A.1
Pillow, T.H.2
Jones, L.R.3
Rothbard, J.B.4
Wender, P.A.5
-
22
-
-
0024209811
-
Autonomous functional domains of chemically synthesized human immunodeficiency virus tat trans-activator protein
-
DOI 10.1016/0092-8674(88)90262-0
-
Green M, Loewenstein PM. 1988. Autonomous functional domains of chemically synthesized human immunodeficiency virus tat trans-activator protein. Cell 55:1179-1188. (Pubitemid 19020070)
-
(1988)
Cell
, vol.55
, Issue.6
, pp. 1179-1188
-
-
Green, M.1
Loewenstein, P.M.2
-
23
-
-
35248880092
-
TAT transduction: The molecular mechanism and therapeutic prospects
-
Gump JM, Dowdy SF. 2007. TAT transduction: the molecular mechanism and therapeutic prospects. Trends Mol Med 13:443-448.
-
(2007)
Trends Mol Med
, vol.13
, pp. 443-448
-
-
Gump, J.M.1
Dowdy, S.F.2
-
24
-
-
13844298046
-
Intracellular delivery of large molecules and small particles by cell-penetrating proteins and peptides
-
DOI 10.1016/j.addr.2004.10.007, PII S0169409X04002716
-
Gupta B, Levchenko TS, Torchilin VP. 2005. Intracellular delivery of large molecules and small particles by cell-penetrating proteins and peptides. Adv Drug Deliv Rev 57:637-651. (Pubitemid 40255564)
-
(2005)
Advanced Drug Delivery Reviews
, vol.57
, Issue.4 SPEC.ISS
, pp. 637-651
-
-
Gupta, B.1
Levchenko, T.S.2
Torchilin, V.P.3
-
25
-
-
33644777422
-
Transactivating transcriptional activator-mediated drug delivery
-
DOI 10.1517/17425247.3.2.177
-
Gupta B, Torchilin VP. 2006. Transactivating transcriptional activator-mediated drug delivery. Expert Opin Drug Deliv 3:177-190. (Pubitemid 43338090)
-
(2006)
Expert Opinion on Drug Delivery
, vol.3
, Issue.2
, pp. 177-190
-
-
Gupta, B.1
Torchilin, V.P.2
-
26
-
-
33646678222
-
Antitumor protein therapy; application of the protein transduction domain to the development of a protein drug for cancer treatment
-
Harada H, Kizaka-Kondoh S, Hiraoka M. 2006. Antitumor protein therapy; application of the protein transduction domain to the development of a protein drug for cancer treatment. Breast Cancer 13:16-26.
-
(2006)
Breast Cancer
, vol.13
, pp. 16-26
-
-
Harada, H.1
Kizaka-Kondoh, S.2
Hiraoka, M.3
-
27
-
-
38049156027
-
Molecular dynamics simulations suggest a mechanism for translocation of the HIV-1 TAT peptide across lipid membranes
-
Herce HD, Garcia AE. 2007. Molecular dynamics simulations suggest a mechanism for translocation of the HIV-1 TAT peptide across lipid membranes. Proc Natl Acad Sci USA 104:20805-20810.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 20805-20810
-
-
Herce, H.D.1
Garcia, A.E.2
-
28
-
-
33747038452
-
Cell-penetrating peptides - A brief introduction
-
Jarver P, Langel U. 2006. Cell-penetrating peptides - a brief introduction. Biochim Biophys Acta 1758:260-263.
-
(2006)
Biochim Biophys Acta
, vol.1758
, pp. 260-263
-
-
Jarver, P.1
Langel, U.2
-
29
-
-
1542609485
-
Transduction peptides: From technology to physiology
-
Joliot A, Prochiantz A. 2004. Transduction peptides: from technology to physiology. Nat Cell Biol 6:189-196.
-
(2004)
Nat Cell Biol
, vol.6
, pp. 189-196
-
-
Joliot, A.1
Prochiantz, A.2
-
30
-
-
27644561216
-
Characterisation of cell-penetrating peptide-mediated peptide delivery
-
DOI 10.1038/sj.bjp.0706279
-
Jones SW, Christison R, Bundell K, Voyce CJ, Brockbank SM, Newham P, Lindsay MA. 2005. Characterisation of cell-penetrating peptide-mediated peptide delivery. Br J Pharmacol 145:1093-1102. (Pubitemid 43079982)
-
(2005)
British Journal of Pharmacology
, vol.145
, Issue.8
, pp. 1093-1102
-
-
Jones, S.W.1
Christison, R.2
Bundell, K.3
Voyce, C.J.4
Brockbank, S.M.V.5
Newham, P.6
Lindsay, M.A.7
-
31
-
-
11844268027
-
Cationic TAT peptide transduction domain enters cells by macropinocytosis
-
Kaplan IM, Wadia JS, Dowdy SF. 2005. Cationic TAT peptide transduction domain enters cells by macropinocytosis. J Control Release 102:247-253.
-
(2005)
J Control Release
, vol.102
, pp. 247-253
-
-
Kaplan, I.M.1
Wadia, J.S.2
Dowdy, S.F.3
-
32
-
-
4344645978
-
Can the pharmaceutical industry reduce attrition rates?
-
Kola I, Landis J. 2004. Can the pharmaceutical industry reduce attrition rates? Nat Rev Drug Discov 3:711-715.
-
(2004)
Nat Rev Drug Discov
, vol.3
, pp. 711-715
-
-
Kola, I.1
Landis, J.2
-
33
-
-
0029098659
-
Domain interaction between NMDA receptor subunits and the postsynaptic density protein PSD-95
-
Kornau HC, Schenker LT, Kennedy MB, Seeburg PH. 1995. Domain interaction between NMDA receptor subunits and the postsynaptic density protein PSD-95. Science 269:1737-1740.
-
(1995)
Science
, vol.269
, pp. 1737-1740
-
-
Kornau, H.C.1
Schenker, L.T.2
Kennedy, M.B.3
Seeburg, P.H.4
-
36
-
-
57349138758
-
Treatment of inflammatory and neuropathic pain by uncoupling Src from the NMDA receptor complex
-
Liu XJ, Gingrich JR, Vargas-Caballero M, Dong YN, Sengar A, Beggs S, Wang SH, Ding HK, Frankland PW, Salter MW. 2008. Treatment of inflammatory and neuropathic pain by uncoupling Src from the NMDA receptor complex. Nat Med 14:1325-1332.
-
(2008)
Nat Med
, vol.14
, pp. 1325-1332
-
-
Liu, X.J.1
Gingrich, J.R.2
Vargas-Caballero, M.3
Dong, Y.N.4
Sengar, A.5
Beggs, S.6
Wang, S.H.7
Ding, H.K.8
Frankland, P.W.9
Salter, M.W.10
-
37
-
-
0141594624
-
Transducing proteins to manipulate intracellular targets
-
Luft FC. 2003. Transducing proteins to manipulate intracellular targets. J Mol Med 81:521-523.
-
(2003)
J Mol Med
, vol.81
, pp. 521-523
-
-
Luft, F.C.1
-
38
-
-
0036289650
-
Positively charged DNA-binding proteins cause apparent cell membrane translocation
-
DOI 10.1006/bbrc.2002.6450
-
Lundberg M, Johansson M. 2002. Positively charged DNA-binding proteins cause apparent cell membrane translocation. Biochem Biophys Res Commun 291:367-371. (Pubitemid 34694414)
-
(2002)
Biochemical and Biophysical Research Communications
, vol.291
, Issue.2
, pp. 367-371
-
-
Lundberg, M.1
Johansson, M.2
-
39
-
-
0027057580
-
Differential roles of NMDA and non-NMDA receptor activation in induction and maintenance of thermal hyperalgesia in rats with painful peripheral mononeuropathy
-
DOI 10.1016/0006-8993(92)90193-D
-
Mao J, Price DD, Hayes RL, Lu J, Mayer DJ. 1992. Differential roles of NMDA and non-NMDA receptor activation in induction and maintenance of thermal hyperalgesia in rats with painful peripheral mononeuropathy. Brain Res 598:271-278. (Pubitemid 23013070)
-
(1992)
Brain Research
, vol.598
, Issue.1-2
, pp. 271-278
-
-
Mao, J.1
Price, D.D.2
Hayes, R.L.3
Lu, J.4
Mayer, D.J.5
-
40
-
-
0030253403
-
Tat-mediated protein delivery can facilitate MHC class I presentation of antigens
-
Moy P, Daikh Y, Pepinsky B, Thomas D, Fawell S, Barsoum J. 1996. Tat-mediated protein delivery can facilitate MHC class I presentation of antigens. Mol Biotechnol 6:105-113.
-
(1996)
Mol Biotechnol
, vol.6
, pp. 105-113
-
-
Moy, P.1
Daikh, Y.2
Pepinsky, B.3
Thomas, D.4
Fawell, S.5
Barsoum, J.6
-
41
-
-
33751251344
-
Influence of protein transduction domains on intracellular delivery of macromolecules
-
Murriel CL, Dowdy SF. 2006. Influence of protein transduction domains on intracellular delivery of macromolecules. Expert Opin Drug Deliv 3:739-746.
-
(2006)
Expert Opin Drug Deliv
, vol.3
, pp. 739-746
-
-
Murriel, C.L.1
Dowdy, S.F.2
-
42
-
-
0344154290
-
Blockade of inflammation and airway hyperresponsiveness in immune-sensitized mice by dominant-negative phosphoinositide 3-kinase-TAT
-
Myou S, Leff AR, Myo S, Boetticher E, Tong J, Meliton AY, Liu J, Munoz NM, Zhu X. 2003a. Blockade of inflammation and airway hyperresponsiveness in immune-sensitized mice by dominant-negative phosphoinositide 3-kinase-TAT. J Exp Med 198:1573-1582.
-
(2003)
J Exp Med
, vol.198
, pp. 1573-1582
-
-
Myou, S.1
Leff, A.R.2
Myo, S.3
Boetticher, E.4
Tong, J.5
Meliton, A.Y.6
Liu, J.7
Munoz, N.M.8
Zhu, X.9
-
43
-
-
0141992835
-
Blockade of airway inflammation and hyperresponsiveness by HIV-TAT-dominant negative Ras
-
Myou S, Zhu X, Myo S, Boetticher E, Meliton AY, Liu J, Munoz NM, Leff AR. 2003b. Blockade of airway inflammation and hyperresponsiveness by HIV-TAT-dominant negative Ras. J Immunol 171:4379-4384.
-
(2003)
J Immunol
, vol.171
, pp. 4379-4384
-
-
Myou, S.1
Zhu, X.2
Myo, S.3
Boetticher, E.4
Meliton, A.Y.5
Liu, J.6
Munoz, N.M.7
Leff, A.R.8
-
44
-
-
0031759170
-
Transduction of full-length TAT fusion proteins into mammalian cells: TAT-p27Kip1 induces cell migration
-
Nagahara H, Vocero-Akbani AM, Snyder EL, Ho A, Latham DG, Lissy NA, Becker-Hapak M, Ezhevsky SA, Dowdy SF. 1998. Transduction of full-length TAT fusion proteins into mammalian cells: TAT-p27Kip1 induces cell migration. Nat Med 4:1449-1452.
-
(1998)
Nat Med
, vol.4
, pp. 1449-1452
-
-
Nagahara, H.1
Vocero-Akbani, A.M.2
Snyder, E.L.3
Ho, A.4
Latham, D.G.5
Lissy, N.A.6
Becker-Hapak, M.7
Ezhevsky, S.A.8
Dowdy, S.F.9
-
45
-
-
10344221003
-
Cellular uptake of arginine-rich peptides: Roles for macropinocytosis and actin rearrangement
-
Nakase I, Niwa M, Takeuchi T, Sonomura K, Kawabata N, Koike Y, Takehashi M, Tanaka S, Ueda K, Simpson JC, Jones AT, Sugiura Y, Futaki S. 2004. Cellular uptake of arginine-rich peptides: roles for macropinocytosis and actin rearrangement. Mol Ther 10:1011-1022.
-
(2004)
Mol Ther
, vol.10
, pp. 1011-1022
-
-
Nakase, I.1
Niwa, M.2
Takeuchi, T.3
Sonomura, K.4
Kawabata, N.5
Koike, Y.6
Takehashi, M.7
Tanaka, S.8
Ueda, K.9
Simpson, J.C.10
Jones, A.T.11
Sugiura, Y.12
Futaki, S.13
-
46
-
-
33846223900
-
Interaction of arginine-rich peptides with membrane-associated proteoglycans is crucial for induction of actin organization and macropinocytosis
-
Nakase I, Tadokoro A, Kawabata N, Takeuchi T, Katoh H, Hiramoto K, Negishi M, Nomizu M, Sugiura Y, Futaki S. 2007. Interaction of arginine-rich peptides with membrane-associated proteoglycans is crucial for induction of actin organization and macropinocytosis. Biochemistry 46:492-501.
-
(2007)
Biochemistry
, vol.46
, pp. 492-501
-
-
Nakase, I.1
Tadokoro, A.2
Kawabata, N.3
Takeuchi, T.4
Katoh, H.5
Hiramoto, K.6
Negishi, M.7
Nomizu, M.8
Sugiura, Y.9
Futaki, S.10
-
47
-
-
38949188925
-
Methodological and cellular aspects that govern the internalization mechanisms of arginine-rich cell-penetrating peptides
-
Nakase I, Takeuchi T, Tanaka G, Futaki S. 2008. Methodological and cellular aspects that govern the internalization mechanisms of arginine-rich cell-penetrating peptides. Adv Drug Deliv Rev 60:598-607.
-
(2008)
Adv Drug Deliv Rev
, vol.60
, pp. 598-607
-
-
Nakase, I.1
Takeuchi, T.2
Tanaka, G.3
Futaki, S.4
-
48
-
-
0036669511
-
Cellular import mediated by nuclear localization signal Peptide sequences
-
Ragin AD, Morgan RA, Chmielewski J. 2002. Cellular import mediated by nuclear localization signal Peptide sequences. Chem Biol 9:943-948.
-
(2002)
Chem Biol
, vol.9
, pp. 943-948
-
-
Ragin, A.D.1
Morgan, R.A.2
Chmielewski, J.3
-
49
-
-
41149128339
-
TAT-mediated delivery of LAD restores pyruvate dehydrogenase complex activity in the mitochondria of patients with LAD deficiency
-
Rapoport M, Saada A, Elpeleg O, Lorberboum-Galski H. 2008. TAT-mediated delivery of LAD restores pyruvate dehydrogenase complex activity in the mitochondria of patients with LAD deficiency. Mol Ther 16:691-697.
-
(2008)
Mol Ther
, vol.16
, pp. 691-697
-
-
Rapoport, M.1
Saada, A.2
Elpeleg, O.3
Lorberboum-Galski, H.4
-
50
-
-
67649086303
-
TAT-based drug delivery system - New directions in protein delivery for new hopes?
-
Rapoport M, Lorberboum-Galski H. 2009. TAT-based drug delivery system - new directions in protein delivery for new hopes? Expert Opin Drug Deliv 6:453-463.
-
(2009)
Expert Opin Drug Deliv
, vol.6
, pp. 453-463
-
-
Rapoport, M.1
Lorberboum-Galski, H.2
-
51
-
-
0026709480
-
The effects of a non-competitive NMDA receptor antagonist, MK-801, on behavioral hyperalgesia and dorsal horn neuronal activity in rats with unilateral inflammation
-
Ren K, Hylden JL, Williams GM, Ruda MA, Dubner R. 1992. The effects of a non-competitive NMDA receptor antagonist, MK-801, on behavioral hyperalgesia and dorsal horn neuronal activity in rats with unilateral inflammation. Pain 50:331-344.
-
(1992)
Pain
, vol.50
, pp. 331-344
-
-
Ren, K.1
Hylden, J.L.2
Williams, G.M.3
Ruda, M.A.4
Dubner, R.5
-
52
-
-
0346460957
-
Cell-penetrating peptides. A reevaluation of the mechanism of cellular uptake
-
Richard JP, Melikov K, Vives E, Ramos C, Verbeure B, Gait MJ, Chernomordik LV, Lebleu B. 2003. Cell-penetrating peptides. A reevaluation of the mechanism of cellular uptake. J Biol Chem 278:585-590.
-
(2003)
J Biol Chem
, vol.278
, pp. 585-590
-
-
Richard, J.P.1
Melikov, K.2
Vives, E.3
Ramos, C.4
Verbeure, B.5
Gait, M.J.6
Chernomordik, L.V.7
Lebleu, B.8
-
53
-
-
17644386231
-
Cellular uptake of unconjugated TAT peptide involves clathrin-dependent endocytosis and heparan sulfate receptors
-
Richard JP, Melikov K, Brooks H, Prevot P, Lebleu B, Chernomordik LV. 2005. Cellular uptake of unconjugated TAT peptide involves clathrin-dependent endocytosis and heparan sulfate receptors. J Biol Chem 280:15300-15306.
-
(2005)
J Biol Chem
, vol.280
, pp. 15300-15306
-
-
Richard, J.P.1
Melikov, K.2
Brooks, H.3
Prevot, P.4
Lebleu, B.5
Chernomordik, L.V.6
-
54
-
-
0033678653
-
Conjugation of arginine oligomers to cyclosporin a facilitates topical delivery and inhibition of inflammation
-
Rothbard JB, Garlington S, Lin Q, Kirschberg T, Kreider E, McGrane PL, Wender PA, Khavari PA. 2000. Conjugation of arginine oligomers to cyclosporin A facilitates topical delivery and inhibition of inflammation. Nat Med 6:1253-1257.
-
(2000)
Nat Med
, vol.6
, pp. 1253-1257
-
-
Rothbard, J.B.1
Garlington, S.2
Lin, Q.3
Kirschberg, T.4
Kreider, E.5
McGrane, P.L.6
Wender, P.A.7
Khavari, P.A.8
-
55
-
-
3543051871
-
Role of membrane potential and hydrogen bonding in the mechanism of translocation of guanidinium-rich peptides into cells
-
Rothbard JB, Jessop TC, Lewis RS, Murray BA, Wender PA. 2004. Role of membrane potential and hydrogen bonding in the mechanism of translocation of guanidinium-rich peptides into cells. J Am Chem Soc 126:9506-9507.
-
(2004)
J Am Chem Soc
, vol.126
, pp. 9506-9507
-
-
Rothbard, J.B.1
Jessop, T.C.2
Lewis, R.S.3
Murray, B.A.4
Wender, P.A.5
-
56
-
-
12344275753
-
Direct observation of anion-mediated translocation of fluorescent oligoarginine carriers into and across bulk liquid and anionic bilayer membranes
-
Sakai N, Takeuchi T, Futaki S, Matile S. 2005. Direct observation of anion-mediated translocation of fluorescent oligoarginine carriers into and across bulk liquid and anionic bilayer membranes. Chembiochem 6:114-122.
-
(2005)
Chembiochem
, vol.6
, pp. 114-122
-
-
Sakai, N.1
Takeuchi, T.2
Futaki, S.3
Matile, S.4
-
57
-
-
0034141430
-
In vivo protein transduction: Intracellular delivery of biologically active proteins, compounds and DNA
-
Schwarze SR, Dowdy SF. 2000. In vivo protein transduction: intracellular delivery of biologically active proteins, compounds and DNA. Trends Pharmacol Sci 21:45-48.
-
(2000)
Trends Pharmacol Sci
, vol.21
, pp. 45-48
-
-
Schwarze, S.R.1
Dowdy, S.F.2
-
58
-
-
0033520487
-
In vivo protein transduction: Delivery of a biologically active protein into the mouse
-
Schwarze SR, Ho A, Vocero-Akbani A, Dowdy SF. 1999. In vivo protein transduction: delivery of a biologically active protein into the mouse. Science 285:1569-1572.
-
(1999)
Science
, vol.285
, pp. 1569-1572
-
-
Schwarze, S.R.1
Ho, A.2
Vocero-Akbani, A.3
Dowdy, S.F.4
-
59
-
-
12344263736
-
Recent advances in the use of protein transduction domains for the delivery of peptides, proteins and nucleic acids in vivo
-
Snyder EL, Dowdy SF. 2005. Recent advances in the use of protein transduction domains for the delivery of peptides, proteins and nucleic acids in vivo. Expert Opin Drug Deliv 2:43-51.
-
(2005)
Expert Opin Drug Deliv
, vol.2
, pp. 43-51
-
-
Snyder, E.L.1
Dowdy, S.F.2
-
60
-
-
0037169486
-
Possible existence of common internalization mechanisms among arginine-rich peptides
-
Suzuki T, Futaki S, Niwa M, Tanaka S, Ueda K, Sugiura Y. 2002. Possible existence of common internalization mechanisms among arginine-rich peptides. J Biol Chem 277:2437-2443.
-
(2002)
J Biol Chem
, vol.277
, pp. 2437-2443
-
-
Suzuki, T.1
Futaki, S.2
Niwa, M.3
Tanaka, S.4
Ueda, K.5
Sugiura, Y.6
-
61
-
-
42549129801
-
Effect of disrupting N-methyl-D-aspartate receptor-postsynaptic density protein-95 interactions on the threshold for halothane anesthesia in mice
-
Tao F, Johns RA. 2008. Effect of disrupting N-methyl-D-aspartate receptor-postsynaptic density protein-95 interactions on the threshold for halothane anesthesia in mice. Anesthesiology 108:882-887.
-
(2008)
Anesthesiology
, vol.108
, pp. 882-887
-
-
Tao, F.1
Johns, R.A.2
-
62
-
-
54949094321
-
Cell-permeable peptide Tat-PSD-95 PDZ2 inhibits chronic inflammatory pain behaviors in mice
-
Tao F, Su Q, Johns RA. 2008. Cell-permeable peptide Tat-PSD-95 PDZ2 inhibits chronic inflammatory pain behaviors in mice. Mol Ther 16:1776-1782.
-
(2008)
Mol Ther
, vol.16
, pp. 1776-1782
-
-
Tao, F.1
Su, Q.2
Johns, R.A.3
-
63
-
-
0035968929
-
Knockdown of PSD-95/SAP90 delays the development of neuropathic pain in rats
-
Tao F, Tao YX, Gonzalez JA, Fang M, Mao P, Johns RA. 2001. Knockdown of PSD-95/SAP90 delays the development of neuropathic pain in rats. NeuroReport 12:3251-3255.
-
(2001)
NeuroReport
, vol.12
, pp. 3251-3255
-
-
Tao, F.1
Tao, Y.X.2
Gonzalez, J.A.3
Fang, M.4
Mao, P.5
Johns, R.A.6
-
64
-
-
0037475139
-
Role of postsynaptic density protein-95 in the maintenance of peripheral nerve injury-induced neuropathic pain in rats
-
Tao F, Tao YX, Mao P, Johns RA. 2003. Role of postsynaptic density protein-95 in the maintenance of peripheral nerve injury-induced neuropathic pain in rats. Neuroscience 117:731-739.
-
(2003)
Neuroscience
, vol.117
, pp. 731-739
-
-
Tao, F.1
Tao, Y.X.2
Mao, P.3
Johns, R.A.4
-
65
-
-
0034128690
-
Expression of PSD-95/SAP90 is critical for N-methyl-D-aspartate receptor-mediated thermal hyperalgesia in the spinal cord
-
Tao YX, Huang YZ, Mei L, Johns RA. 2000. Expression of PSD-95/SAP90 is critical for N-methyl-D-aspartate receptor-mediated thermal hyperalgesia in the spinal cord. Neuroscience 98:201-206.
-
(2000)
Neuroscience
, vol.98
, pp. 201-206
-
-
Tao, Y.X.1
Huang, Y.Z.2
Mei, L.3
Johns, R.A.4
-
66
-
-
50849144942
-
Cell penetrating peptide-modified pharmaceutical nanocarriers for intracellular drug and gene delivery
-
Torchilin VP. 2008a. Cell penetrating peptide-modified pharmaceutical nanocarriers for intracellular drug and gene delivery. Biopolymers 90:604-610.
-
(2008)
Biopolymers
, vol.90
, pp. 604-610
-
-
Torchilin, V.P.1
-
67
-
-
38949192863
-
Tat peptide-mediated intracellular delivery of pharmaceutical nanocarriers
-
Torchilin VP. 2008b. Tat peptide-mediated intracellular delivery of pharmaceutical nanocarriers. Adv Drug Deliv Rev 60:548-558.
-
(2008)
Adv Drug Deliv Rev
, vol.60
, pp. 548-558
-
-
Torchilin, V.P.1
-
68
-
-
0035902477
-
TAT peptide on the surface of liposomes affords their efficient intracellular delivery even at low temperature and in the presence of metabolic inhibitors
-
Torchilin VP, Rammohan R, Weissig V, Levchenko TS. 2001. TAT peptide on the surface of liposomes affords their efficient intracellular delivery even at low temperature and in the presence of metabolic inhibitors. Proc Natl Acad Sci USA 98:8786-8791.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 8786-8791
-
-
Torchilin, V.P.1
Rammohan, R.2
Weissig, V.3
Levchenko, T.S.4
-
69
-
-
0037452668
-
Cell transfection in vitro and in vivo with nontoxic TAT peptide-liposome-DNA complexes
-
Torchilin VP, Levchenko TS, Rammohan R, Volodina N, Papahadjopoulos- Sternberg B, D'Souza GG. 2003. Cell transfection in vitro and in vivo with nontoxic TAT peptide-liposome-DNA complexes. Proc Natl Acad Sci USA 100:1972-1977.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 1972-1977
-
-
Torchilin, V.P.1
Levchenko, T.S.2
Rammohan, R.3
Volodina, N.4
Papahadjopoulos-Sternberg, B.5
D'Souza, G.G.6
-
70
-
-
33748648777
-
Cargo-dependent mode of uptake and bioavailability of TAT-containing proteins and peptides in living cells
-
Tunnemann G, Martin RM, Haupt S, Patsch C, Edenhofer F, Cardoso MC. 2006. Cargo-dependent mode of uptake and bioavailability of TAT-containing proteins and peptides in living cells. FASEB J 20:1775-1784.
-
(2006)
FASEB J
, vol.20
, pp. 1775-1784
-
-
Tunnemann, G.1
Martin, R.M.2
Haupt, S.3
Patsch, C.4
Edenhofer, F.5
Cardoso, M.C.6
-
71
-
-
0030904245
-
A truncated HIV-1 Tat protein basic domain rapidly translocates through the plasma membrane and accumulates in the cell nucleus
-
Vives E, Brodin P, Lebleu B. 1997. A truncated HIV-1 Tat protein basic domain rapidly translocates through the plasma membrane and accumulates in the cell nucleus. J Biol Chem 272:16010-16017.
-
(1997)
J Biol Chem
, vol.272
, pp. 16010-16017
-
-
Vives, E.1
Brodin, P.2
Lebleu, B.3
-
73
-
-
2342595835
-
Transducible TAT-HA fusogenic peptide enhances escape of TAT-fusion proteins after lipid raft macropinocytosis
-
Wadia JS, Stan RV, Dowdy SF. 2004. Transducible TAT-HA fusogenic peptide enhances escape of TAT-fusion proteins after lipid raft macropinocytosis. Nat Med 10:310-315.
-
(2004)
Nat Med
, vol.10
, pp. 310-315
-
-
Wadia, J.S.1
Stan, R.V.2
Dowdy, S.F.3
-
74
-
-
0035144105
-
Genetic enhancement of inflammatory pain by forebrain NR2B overexpression
-
Wei F, Wang GD, Kerchner GA, Kim SJ, Xu HM, Chen ZF, Zhuo M. 2001. Genetic enhancement of inflammatory pain by forebrain NR2B overexpression. Nat Neurosci 4:164-169.
-
(2001)
Nat Neurosci
, vol.4
, pp. 164-169
-
-
Wei, F.1
Wang, G.D.2
Kerchner, G.A.3
Kim, S.J.4
Xu, H.M.5
Chen, Z.F.6
Zhuo, M.7
-
75
-
-
0034700141
-
The design, synthesis, and evaluation of molecules that enable or enhance cellular uptake: Peptoid molecular transporters
-
Wender PA, Mitchell DJ, Pattabiraman K, Pelkey ET, Steinman L, Rothbard JB. 2000. The design, synthesis, and evaluation of molecules that enable or enhance cellular uptake: peptoid molecular transporters. Proc Natl Acad Sci USA 97:13003-13008.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 13003-13008
-
-
Wender, P.A.1
Mitchell, D.J.2
Pattabiraman, K.3
Pelkey, E.T.4
Steinman, L.5
Rothbard, J.B.6
-
76
-
-
45849113975
-
Organelle-targeted delivery of biological macromolecules using the protein transduction domain: Potential applications for Peptide aptamer delivery into the nucleus
-
Yoshikawa T, Sugita T, Mukai Y, Yamanada N, Nagano K, Nabeshi H, Yoshioka Y, Nakagawa S, Abe Y, Kamada H, Tsunoda S, Tsutsumi Y. 2008. Organelle-targeted delivery of biological macromolecules using the protein transduction domain: potential applications for Peptide aptamer delivery into the nucleus. J Mol Biol 380:777-782.
-
(2008)
J Mol Biol
, vol.380
, pp. 777-782
-
-
Yoshikawa, T.1
Sugita, T.2
Mukai, Y.3
Yamanada, N.4
Nagano, K.5
Nabeshi, H.6
Yoshioka, Y.7
Nakagawa, S.8
Abe, Y.9
Kamada, H.10
Tsunoda, S.11
Tsutsumi, Y.12
-
77
-
-
38449084627
-
Cellular uptake and lysosomal delivery of galactocerebrosidase tagged with the HIV Tat protein transduction domain
-
Zhang XY, Dinh A, Cronin J, Li SC, Reiser J. 2008. Cellular uptake and lysosomal delivery of galactocerebrosidase tagged with the HIV Tat protein transduction domain. J Neurochem 104:1055-1064.
-
(2008)
J Neurochem
, vol.104
, pp. 1055-1064
-
-
Zhang, X.Y.1
Dinh, A.2
Cronin, J.3
Li, S.C.4
Reiser, J.5
-
78
-
-
55249113736
-
TAT-mediated intracellular delivery of NPM-derived peptide induces apoptosis in leukemic cells and suppresses leukemogenesis in mice
-
Zhou Y, Du W, Koretsky T, Bagby GC, Pang Q. 2008. TAT-mediated intracellular delivery of NPM-derived peptide induces apoptosis in leukemic cells and suppresses leukemogenesis in mice. Blood 112:2474-2483.
-
(2008)
Blood
, vol.112
, pp. 2474-2483
-
-
Zhou, Y.1
Du, W.2
Koretsky, T.3
Bagby, G.C.4
Pang, Q.5
-
79
-
-
0346688716
-
Interaction of the Protein Transduction Domain of HIV-1 TAT with Heparan Sulfate: Binding Mechanism and Thermodynamic Parameters
-
Ziegler A, Seelig J. 2004. Interaction of the protein transduction domain of HIV-1 TAT with heparan sulfate: binding mechanism and thermodynamic parameters. Biophys J 86:254-263. (Pubitemid 38067453)
-
(2004)
Biophysical Journal
, vol.86
, Issue.1
, pp. 254-263
-
-
Ziegler, A.1
Seelig, J.2
|