Cellular uptake and lysosomal delivery of galactocerebrosidase tagged with the HIV Tat protein transduction domain

Journal of Neurochemistry

Volumn 104, Issue 4, 2008, Pages 1055-1064

  Zhang, Xian Yang ^a   Dinh, Annie ^a   Cronin, James ^a   Li, Su Chen ^b   Reiser, Jakob ^a  

^a LOUISIANA STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b TULANE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Galactocerebrosidase; Globoid cell leukodystrophy; Lentiviral vectors; Protein transduction; Tat protein transduction domain; Twitcher mouse model

Indexed keywords

GALACTOSYLCERAMIDASE; GALACTOSYLCERAMIDE; SOMATOMEDIN B RECEPTOR; TRANSACTIVATOR PROTEIN;

ANALYTIC METHOD; ANIMAL CELL; ARTICLE; BRAIN CORTEX; CARBOXY TERMINAL SEQUENCE; COMPARATIVE STUDY; CONTROLLED STUDY; ENDOCYTOSIS; FIBROBLAST; GLOBOID CELL LEUKODYSTROPHY; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; INTRACELLULAR TRANSPORT; LYSOSOME; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN TRANSPORT;

AMINO ACID SEQUENCE; ANIMALS; CELLS, CULTURED; CERCOPITHECUS AETHIOPS; COS CELLS; FIBROBLASTS; GALACTOSYLCERAMIDASE; HELA CELLS; HUMANS; LYSOSOMES; MICE; MICE, NEUROLOGIC MUTANTS; MOLECULAR SEQUENCE DATA; PROTEIN STRUCTURE, TERTIARY; TAT GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS; TRANSDUCTION, GENETIC;

HUMAN IMMUNODEFICIENCY VIRUS 1; MURINAE; MUS;

EID: 38449084627     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2007.05030.x     Document Type: Article

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