Chromosomal instability by inefficient Mps1 auto-activation due to a weakened mitotic checkpoint and lagging chromosomes

PLoS ONE

Volumn 3, Issue 6, 2008, Pages

  Jelluma, Nannette ^a   Brenkman, Arjan B ^a   McLeod, Ian ^b   Yates III, John R ^b   Cleveland, Don W ^c   Medema, René H ^a   Kops, Geert J P L ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MONOPOLAR SPINDLE KINASE 1; PROTEIN KINASE; CELL CYCLE PROTEIN; PROTEIN SERINE THREONINE KINASE; TTK PROTEIN, HUMAN;

ANAPHASE; ARTICLE; AUTOPHOSPHORYLATION; CELL VIABILITY; CHROMOSOMAL INSTABILITY; CHROMOSOME SEGREGATION; CONTROLLED STUDY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; MITOSIS; MUTANT; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN MODIFICATION; PROTEIN PHOSPHORYLATION; WILD TYPE; CELL LINE; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; HUMAN CHROMOSOME; PHOSPHORYLATION; PHYSIOLOGY;

CELL CYCLE PROTEINS; CELL LINE; CHROMOSOMAL INSTABILITY; CHROMOSOMES, HUMAN; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; MITOSIS; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES;

EID: 48749132272     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0002415     Document Type: Article

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