-
2
-
-
5644239087
-
Alzheimer disease: Mechanistic understanding predicts novel therapies
-
Selkoe DJ. Alzheimer disease: mechanistic understanding predicts novel therapies. Ann Intern Med 2004; 140: 627-638.
-
(2004)
Ann Intern Med
, vol.140
, pp. 627-638
-
-
Selkoe, D.J.1
-
3
-
-
85031336695
-
Peptydy amyloidu beta w mózgu starczym i w patomechanizmie choroby Alzheimera
-
Strosznajder J.B., Mossakowski J.M. (red.). Upowszechnianie Nauki - Oświata "UN-O", Warszawa
-
Strosznajder J.B., Łałowski M.M. Peptydy amyloidu beta w mózgu starczym i w patomechanizmie choroby Alzheimera. W: Strosznajder J.B., Mossakowski J.M. (red.). Mózg a starzenie. Upowszechnianie Nauki - Oświata "UN-O", Warszawa 2001.
-
(2001)
Mózg a Starzenie
-
-
Strosznajder, J.B.1
Łałowski, M.M.2
-
4
-
-
0037135111
-
The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics
-
DOI 10.1126/science.1072994
-
Hardy J., Selkoe DJ. The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. Science 2002; 297: 353-356. (Pubitemid 34790756)
-
(2002)
Science
, vol.297
, Issue.5580
, pp. 353-356
-
-
Hardy, J.1
Selkoe, D.J.2
-
5
-
-
0026646605
-
Isolation and quantification of soluble Alzheimer's beta-peptide from biological fluids
-
i wsp.
-
Seubert P., Vigo-Pelfrey C., Esch F. i wsp. Isolation and quantification of soluble Alzheimer's beta-peptide from biological fluids. Nature 1992; 359: 325-327.
-
(1992)
Nature
, vol.359
, pp. 325-327
-
-
Seubert, P.1
Vigo-Pelfrey, C.2
Esch, F.3
-
6
-
-
0027258525
-
The carboxy terminus of the beta amyloid protein is critical for the seeding of amyloid formation: Implications for the pathogenesis of Alzheimer's disease
-
Jarrett J.T., Berger E.P., Lansbury P.T. Jr. The carboxy terminus of the beta amyloid protein is critical for the seeding of amyloid formation: implications for the pathogenesis of Alzheimer's disease. Biochemistry 1993; 32: 4693-4697.
-
(1993)
Biochemistry
, vol.32
, pp. 4693-4697
-
-
Jarrett, J.T.1
Berger, E.P.2
Lansbury Jr., P.T.3
-
7
-
-
0025753852
-
The molecular pathology of Alzheimer's disease
-
Selkoe DJ. The molecular pathology of Alzheimer's disease. Neuron 1991; 6: 487-498.
-
(1991)
Neuron
, vol.6
, pp. 487-498
-
-
Selkoe, D.J.1
-
8
-
-
11544279355
-
1-42 are potent central nervous system neurotoxins
-
DOI 10.1073/pnas.95.11.6448
-
Lambert M.P., Barlow A.K., Chromy B.A. i wsp. Diffusible, nonfibrillar figands derived from Abeta1-42 are potent central nervous system neurotoxins. Proc Natl Acad Sci USA 1998; 95: 6448-6453. (Pubitemid 28249033)
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, Issue.11
, pp. 6448-6453
-
-
Lambert, M.P.1
Barlow, A.K.2
Chromy, B.A.3
Edwards, C.4
Freed, R.5
Liosatos, M.6
Morgan, T.E.7
Rozovsky, I.8
Trommer, B.9
Viola, K.L.10
Wals, P.11
Zhang, C.12
Finch, C.E.13
Krafft, G.A.14
Klein, W.L.15
-
9
-
-
0033570337
-
Protofibrillar intermediates of amyloid beta-protein induce acute electrophysiological changes and progressive neurotoxicity in cortical neurons
-
i wsp.
-
Hartley D.M., Walsh D.M., Ye C.P. i wsp. Protofibrillar intermediates of amyloid beta-protein induce acute electrophysiological changes and progressive neurotoxicity in cortical neurons. J Neurosci 1999; 19: 8876-8884.
-
(1999)
J Neurosci
, vol.19
, pp. 8876-8884
-
-
Hartley, D.M.1
Walsh, D.M.2
Ye, C.P.3
-
10
-
-
33645038471
-
A specific amyloid-beta protein assembly in the brain impairs memory
-
i wsp.
-
Lesné S., Koh M.T., Kotilinek L. i wsp. A specific amyloid-beta protein assembly in the brain impairs memory. Nature 2006; 440: 352-357.
-
(2006)
Nature
, vol.440
, pp. 352-357
-
-
Lesné, S.1
Koh, M.T.2
Kotilinek, L.3
-
11
-
-
33645505550
-
Effects of secreted oligomers of amyloid beta-protein on hippocampal synaptic plasticity: A potent role for trimers
-
i wsp.
-
Townsend M., Shankar G.M., Mehta T. i wsp. Effects of secreted oligomers of amyloid beta-protein on hippocampal synaptic plasticity: a potent role for trimers. J Physiol 2006; 572: 477-492.
-
(2006)
J Physiol
, vol.572
, pp. 477-492
-
-
Townsend, M.1
Shankar, G.M.2
Mehta, T.3
-
12
-
-
0032590054
-
Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease
-
i wsp.
-
McLean C.A., Cherny R.A., Eraser F.W. i wsp. Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease. Ann Neurol 1999; 46: 860-866.
-
(1999)
Ann Neurol
, vol.46
, pp. 860-866
-
-
McLean, C.A.1
Cherny, R.A.2
Eraser, F.W.3
-
13
-
-
34548258322
-
Accelerating amyloid-beta fibrillization reduces oligomer levels and functional deficits in Alzheimer disease mouse models
-
DOI 10.1074/jbc.M701078200
-
Cheng I.H., Scearce-Levie K., Legleiter J. i wsp. Accelerating amyloid-beta fibrillization reduces oligomer levels and functional deficits in Alzheimer disease mouse models. J Biol Chem 2007; 282: 23818-23828. (Pubitemid 47328006)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.33
, pp. 23818-23828
-
-
Cheng, I.H.1
Scearce-Levie, K.2
Legleiter, J.3
Palop, J.J.4
Gerstein, H.5
Bien-Ly, N.6
Puolivali, J.7
Lesne, S.8
Ashe, K.H.9
Muchowski, P.J.10
Mucke, L.11
-
14
-
-
0037041426
-
Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo
-
DOI 10.1038/416535a
-
Walsh D.M., Klyubin I., Fadeeva J.V. i wsp. Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo. Nature 2002; 416: 535-539. (Pubitemid 34288854)
-
(2002)
Nature
, vol.416
, Issue.6880
, pp. 535-539
-
-
Walsh, D.M.1
Klyubin, I.2
Fadeeva, J.V.3
Cullen, W.K.4
Anwyl, R.5
Wolfe, M.S.6
Rowan, M.J.7
Selkoe, D.J.8
-
15
-
-
33947314641
-
Natural oligomers of the Alzheimer amyloid-beta protein induce reversible synapse loss by modulating an NMDA-type glutamate receptor-dependent signaling pathway
-
i wsp.
-
Shankar G.M., Bloodgood B.L., Townsend M. i wsp. Natural oligomers of the Alzheimer amyloid-beta protein induce reversible synapse loss by modulating an NMDA-type glutamate receptor-dependent signaling pathway. J Neurosci 2007; 27: 2866-2875.
-
(2007)
J Neurosci
, vol.27
, pp. 2866-2875
-
-
Shankar, G.M.1
Bloodgood, B.L.2
Townsend, M.3
-
16
-
-
0037015020
-
The Alzheimer's a beta-peptide is deposited at sites of complement activation in pathologic deposits associated with aging and age-related macular degeneration
-
i wsp.
-
Johnson LV, Leitner WE, Rivest A.J. i wsp. The Alzheimer's A beta-peptide is deposited at sites of complement activation in pathologic deposits associated with aging and age-related macular degeneration. Proc Natl Acad Sci USA 2002; 99: 11830-11835.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 11830-11835
-
-
Johnson, L.V.1
Leitner, W.E.2
Rivest, A.J.3
-
17
-
-
0035066332
-
Alzheimer's disease: Genes, proteins, and therapy
-
Selkoe DJ. Alzheimer's disease: genes, proteins, and therapy. Physiol Rev 2001; 81: 741-766.
-
(2001)
Physiol Rev
, vol.81
, pp. 741-766
-
-
Selkoe, D.J.1
-
18
-
-
4944258716
-
The role of inflammation in Alzheimer's disease
-
Tuppo E.E., Arias H.R. The role of inflammation in Alzheimer's disease. Int J Biochem Cell Biol 2005; 37: 289-305.
-
(2005)
Int J Biochem Cell Biol
, vol.37
, pp. 289-305
-
-
Tuppo, E.E.1
Arias, H.R.2
-
19
-
-
0029795517
-
Inflammation, Abeta deposition, and neurofibrillary tangle formation as correlates of Alzheimer's disease neurodegeneration
-
Lue L.F., Brachova L., Civin WH. i wsp. Inflammation, A beta deposition, and neurofibrillary tangle formation as correlates of Alzheimer's disease neurodegeneration. J Neuropathol Exp Neurol 1996; 55: 1083-1088. (Pubitemid 26338020)
-
(1996)
Journal of Neuropathology and Experimental Neurology
, vol.55
, Issue.10
, pp. 1083-1088
-
-
Lue, L.-F.1
Brachova, L.2
Civin, W.H.3
Rogers, J.4
-
20
-
-
0035866060
-
Beta-Amyloid stimulation of microglia and monocytes results in TNFalpha-dependent expression of inducible nitric oxide synthase and neuronal apoptosis
-
i wsp.
-
Combs C.K., Karlo J.C., Kao S-C. i wsp. beta-Amyloid stimulation of microglia and monocytes results in TNFalpha-dependent expression of inducible nitric oxide synthase and neuronal apoptosis. J Neurosci 2001; 21: 1179-1188.
-
(2001)
J Neurosci
, vol.21
, pp. 1179-1188
-
-
Combs, C.K.1
Karlo, J.C.2
Kao, S.-C.3
-
21
-
-
0035695987
-
Gene expression profiling of amyloid beta peptide-stimulated human post-mortem brain microglia
-
DOI 10.1016/S0197-4580(01)00306-2, PII S0197458001003062
-
Walker D.G., Lue L.F., Beach T.G. Gene expression profiling of amyloid beta peptide-stimulated human post-mortem brain microglia. Neurobiol Aging 2001; 22: 957-966. (Pubitemid 34066564)
-
(2001)
Neurobiology of Aging
, vol.22
, Issue.6
, pp. 957-966
-
-
Walker, D.G.1
Lue, L.-F.2
Beach, T.G.3
-
22
-
-
32544456878
-
Glia as a therapeutic target: Selective suppression of human amyloid-beta-induced upregulation of brain proinflammatory cytokine production attenuates neurodegeneration
-
i wsp.
-
Ralay Ranaivo H., Craft J.M., Hu W. i wsp. Glia as a therapeutic target: selective suppression of human amyloid-beta-induced upregulation of brain proinflammatory cytokine production attenuates neurodegeneration. J Neurosci 2006; 26: 662-670.
-
(2006)
J Neurosci
, vol.26
, pp. 662-670
-
-
Ralay Ranaivo, H.1
Craft, J.M.2
Hu, W.3
-
23
-
-
33846538660
-
Synapse Loss and Microglial Activation Precede Tangles in a P301S Tauopathy Mouse Model
-
DOI 10.1016/j.neuron.2007.01.010, PII S089662730700030X
-
Yoshiyama Y., Higuchi M., Zhang B. i wsp. Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model. Neuron 2007; 53: 337-351. (Pubitemid 46161268)
-
(2007)
Neuron
, vol.53
, Issue.3
, pp. 337-351
-
-
Yoshiyama, Y.1
Higuchi, M.2
Zhang, B.3
Huang, S.-M.4
Iwata, N.5
Saido, T.6
Maeda, J.7
Suhara, T.8
Trojanowski, J.Q.9
Lee, V.M.-Y.10
-
24
-
-
0035936004
-
Nonsteroidal antiinflammatory drugs and the risk of Alzheimer's disease
-
in t'Veld B., Ruitenberg A., Hofman A. Nonsteroidal antiinflammatory drugs and the risk of Alzheimer's disease. N Engl J Med 2001; 345: 1515-1521.
-
(2001)
N Engl J Med
, vol.345
, pp. 1515-1521
-
-
T'Veld, B.1
Ruitenberg, A.2
Hofman, A.3
-
25
-
-
0038375640
-
Effect of non-steroidal anti-inflammatory drugs on risk of Alzheimer's disease: Systematic review and meta-analysis of observational studies
-
Etminan M., Gill S., Samii A. Effect of non-steroidal anti-inflammatory drugs on risk of Alzheimer's disease: systematic review and meta-analysis of observational studies. BMJ 2003; 327: 128. (Pubitemid 36876203)
-
(2003)
British Medical Journal
, vol.327
, Issue.7407
, pp. 128-131
-
-
Etminan, M.1
Gill, S.2
Samii, A.3
-
26
-
-
3242803587
-
Nonsteroidal anti-inflammatory drugs for the prevention of Alzheimer's disease: A systematic review
-
DOI 10.1159/000078501
-
Szekely C.A., Thorne J.E., Zandi P.P. i wsp. Nonsteroidal anti-inflammatory drugs for the prevention of Alzheimer's disease: a systematic review. Neuroepidemiology 2004; 23: 159-169. (Pubitemid 38980441)
-
(2004)
Neuroepidemiology
, vol.23
, Issue.4
, pp. 159-169
-
-
Szekely, C.A.1
Thorne, J.E.2
Zandi, P.P.3
Ek, M.4
Messias, E.5
Breitner, J.C.S.6
Goodman, S.N.7
-
28
-
-
0036499224
-
Prostaglandins as modulators of immunity
-
i wsp.
-
Harris S.G., Padilla J., Koumas L. i wsp. Prostaglandins as modulators of immunity. Trends Immunol 2002; 23: 144-150.
-
(2002)
Trends Immunol
, vol.23
, pp. 144-150
-
-
Harris, S.G.1
Padilla, J.2
Koumas, L.3
-
29
-
-
0345861750
-
Synaptic lipid signaling: Significance of polyunsaturated fatty acids and plateled-activating factor
-
Bazan N.G. Synaptic lipid signaling: significance of polyunsaturated fatty acids and plateled-activating factor. J Lipid Res 2003; 44: 2221-2233.
-
(2003)
J Lipid Res
, vol.44
, pp. 2221-2233
-
-
Bazan, N.G.1
-
30
-
-
0030479496
-
Prostaglandin endoperoxide H synthases (cyclooxygenases)-1 and -2
-
Smith W.L., Garavito R.M., DeWitt D.L. Prostaglandin endoperoxide H synthases (cyclooxygenases)-1 and -2. J Biol Chem 1996; 271: 33157-33160.
-
(1996)
J Biol Chem
, vol.271
, pp. 33157-33160
-
-
Smith, W.L.1
Garavito, R.M.2
DeWitt, D.L.3
-
31
-
-
0027293391
-
Expression of mRNA for cyclooxygenase-1 and cyclooxygenase-2 in human tissues
-
O'Neill G.P., Ford-Hutchinson A.W. Expression of mRNA for cyclooxygenase-1 and cyclooxygenase-2 in human tissues. FEBS Lett 1993; 330: 156-160. (Pubitemid 23265121)
-
(1993)
FEBS Letters
, vol.330
, Issue.2
, pp. 156-160
-
-
O'Neill, G.P.1
Ford-Hutchinson, A.W.2
-
32
-
-
77951279168
-
Cyklooksygenazy. I. Rola w odczynie zapalnym
-
Kołaczkowska E. Cyklooksygenazy. I. Rola w odczynie zapalnym. Post Biol Kom 2002; 29: 533-554.
-
(2002)
Post Biol Kom
, vol.29
, pp. 533-554
-
-
Kołaczkowska, E.1
-
33
-
-
0036156424
-
Cyclooxygenase-2 - 10 years later
-
Hinz B., Brune K. Cyclooxygenase-2 - 10 years later. J Pharmacol Exp Ther 2002; 300: 367-375.
-
(2002)
J Pharmacol Exp Ther
, vol.300
, pp. 367-375
-
-
Hinz, B.1
Brune, K.2
-
34
-
-
1842714301
-
Neuroinflammation, COX-2, and ALS - A dual role?
-
Consilvio C., Vincent A.M., Feldman E.L. Neuroinflammation, COX-2, and ALS - a dual role? Exp Neurol 2004; 187: 1-10.
-
(2004)
Exp Neurol
, vol.187
, pp. 1-10
-
-
Consilvio, C.1
Vincent, A.M.2
Feldman, E.L.3
-
35
-
-
25644445318
-
Acetaminophen and the cyclooxygenase-3 puzzle: Sorting out facts, fictions, and uncertainties
-
Kis B., Snipes J.A., Busija D.W. Acetaminophen and the cyclooxygenase-3 puzzle: sorting out facts, fictions, and uncertainties. J Pharmacol Exp Ther 2005; 315: 1-7.
-
(2005)
J Pharmacol Exp Ther
, vol.315
, pp. 1-7
-
-
Kis, B.1
Snipes, J.A.2
Busija, D.W.3
-
36
-
-
4444333049
-
Cyclooxygenase-2 (COX-2) in inflammatory and degenerative brain diseases
-
Minghetti L. Cyclooxygenase-2 (COX-2) in inflammatory and degenerative brain diseases. J Neuropathol Exp Neurol 2004; 63: 901-910. (Pubitemid 39202493)
-
(2004)
Journal of Neuropathology and Experimental Neurology
, vol.63
, Issue.9
, pp. 901-910
-
-
Minghetti, L.1
-
37
-
-
0032725481
-
Cyclooxygenase-1 in human Alzheimer and control brain: Quantitative analysis of expression by microglia and CA3 hippocampal neurons
-
Yermakova A.V., Rollins J., Callahan L.M. i wsp. Cyclooxygenase-1 in human Alzheimer and control brain: quantitative analysis of expression by microglia and CA3 hippocampal neurons. J Neuropathol Exp Neurol 1999; 58: 1135-1146. (Pubitemid 29519837)
-
(1999)
Journal of Neuropathology and Experimental Neurology
, vol.58
, Issue.11
, pp. 1135-1146
-
-
Yermakova, A.V.1
Rollins, J.2
Callahan, L.M.3
Rogers, J.4
O'Banion, M.K.5
-
38
-
-
0014117395
-
Identification of prostaglandins in central nervous tissues of the cat and chicken
-
Horton E.W., Main I.H. Identification of prostaglandins in central nervous tissues of the cat and chicken. Br J Pharmacol Chemother 1967; 30: 582-602.
-
(1967)
Br J Pharmacol Chemother
, vol.30
, pp. 582-602
-
-
Horton, E.W.1
Main, I.H.2
-
39
-
-
0013933124
-
Spontaneous and evoked release of prostaglandins from cerebral cortex of anesthetized cats
-
Ramwell P.W., Shaw J.E. Spontaneous and evoked release of prostaglandins from cerebral cortex of anesthetized cats. Am J Physiol 1966; 211: 125-134.
-
(1966)
Am J Physiol
, vol.211
, pp. 125-134
-
-
Ramwell, P.W.1
Shaw, J.E.2
-
40
-
-
0038391161
-
Deficits in spatial learning and synaptic plasticity induced by the rapid and competitive broad-spectrum cyclooxygenase inhibitor ibuprofen are reversed by increasing endogenous brain-derived neurotrophic factor
-
DOI 10.1046/j.1460-9568.2003.02643.x
-
Shaw K.N., Commins S., O'Mara S.M. Deficits in spatial learning and synaptic plasticity induced by the rapid and competitive broad-spectrum cyclooxygenase inhibitor Ibuprofen are reversed by increasing endogenous brain-derived neurotrophic factor. Eur J Neurosci 2003; 17: 2438-2446. (Pubitemid 36793752)
-
(2003)
European Journal of Neuroscience
, vol.17
, Issue.11
, pp. 2438-2446
-
-
Shaw, K.N.1
Commins, S.2
O'Mara, S.M.3
-
41
-
-
0027290813
-
Expression of a mitogen-inducible cyclooxygenase in brain neurons: Regulation by synaptic activity and glucocorticoids
-
DOI 10.1016/0896-6273(93)90192-T
-
Yamagata K., Andreasson K.I., Kaufmann W.E. i wsp. Expression of a mitogen-inducible cyclooxygenase in brain neurons: regulation by synaptic activity and glucocorticoids. Neuron 1993; 11: 371-386. (Pubitemid 23250354)
-
(1993)
Neuron
, vol.11
, Issue.2
, pp. 371-386
-
-
Yamagata, K.1
Andreasson, K.I.2
Kaufmann, W.E.3
Barnes, C.A.4
Worley, P.F.5
-
42
-
-
0028010036
-
Eicosanoids in synaptic transmission
-
Piomelli D. Eicosanoids in synaptic transmission. Crit Rev Neurobiol 1994; 8: 65-83.
-
(1994)
Crit Rev Neurobiol
, vol.8
, pp. 65-83
-
-
Piomelli, D.1
-
43
-
-
0036082805
-
2 signaling in hippocampal long-term synaptic plasticity
-
Chen C, Magee J.C., Bazan N.G. Cyclooxygenase-2 regulates prostaglandin E-2 signaling in hippocampal long-term synaptic plasticity. J Neurophysiol 2002; 87: 2851-2857. (Pubitemid 34670665)
-
(2002)
Journal of Neurophysiology
, vol.87
, Issue.6
, pp. 2851-2857
-
-
Chen, C.1
Magee, J.C.2
Bazan, N.G.3
-
44
-
-
12544250740
-
Endogenous PGE2 regulates membrane excitability and synaptic transmission in hippocampal CA1 pyramidal neurons
-
Chen C., Bazan N.G. Endogenous PGE2 regulates membrane excitability and synaptic transmission in hippocampal CA1 pyramidal neurons. J Neurophysiol 2005; 93: 929-941.
-
(2005)
J Neurophysiol
, vol.93
, pp. 929-941
-
-
Chen, C.1
Bazan, N.G.2
-
45
-
-
0028969527
-
Different intracellular locations for prostaglandin endoperoxide H synthase-1 and -2
-
i wsp.
-
Morita I., Schindler M., Regier M.K. i wsp. Different intracellular locations for prostaglandin endoperoxide H synthase-1 and -2. J Biol Chem 1995; 270: 10902-10908.
-
(1995)
J Biol Chem
, vol.270
, pp. 10902-10908
-
-
Morita, I.1
Schindler, M.2
Regier, M.K.3
-
46
-
-
13044263122
-
2 receptors
-
DOI 10.1073/pnas.95.26.15792
-
Bhattacharya M., Peri K.G., Almazan G. i wsp. Nuclear localization of prostaglandin E2 receptors. Proc Natl Acad Sci USA 1998; 95: 15792-15797. (Pubitemid 29018779)
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, Issue.26
, pp. 15792-15797
-
-
Bhattacharya, M.1
Peri, K.G.2
Almazan, G.3
Ribeiro-Da-Silva, A.4
Shichi, H.5
Durocher, Y.6
Abramovitz, M.7
Hou, X.8
Varma, D.R.9
Chemtob, S.10
-
47
-
-
0031821321
-
Indomethacin reverses the microglial response to amyloid beta-protein
-
i wsp.
-
Netland E.E., Newton J.L., Majocha L.E. i wsp. Indomethacin reverses the microglial response to amyloid beta-protein. Neurobiol Aging 1998; 19: 201-204.
-
(1998)
Neurobiol Aging
, vol.19
, pp. 201-204
-
-
Netland, E.E.1
Newton, J.L.2
Majocha, L.E.3
-
48
-
-
0031900411
-
Nonsteroidal anti-inflammatory drug use and Alzheimer-type pathology in aging
-
Mackenzie I.R., Munoz D.G. Nonsteroidal anti-inflammatory drug use and Alzheimer-type pathology in aging. Neurology 1998; 50: 986-990.
-
(1998)
Neurology
, vol.50
, pp. 986-990
-
-
Mackenzie, I.R.1
Munoz, D.G.2
-
49
-
-
0035141118
-
Cyclooxygenase expression in microglia and neurons in Alzheimer's disease and control brain
-
i wsp.
-
Hoozemans J.J., Rozemuller A.J., Janssen I. i wsp. Cyclooxygenase expression in microglia and neurons in Alzheimer's disease and control brain. Acta Neuropathol 2001; 101: 2-8.
-
(2001)
Acta Neuropathol
, vol.101
, pp. 2-8
-
-
Hoozemans, J.J.1
Rozemuller, A.J.2
Janssen, I.3
-
50
-
-
0032605115
-
Expression of cyclooxygenase-2 in astrocytes of human brain after global ischemia
-
i wsp.
-
Maślińska D., Woźniak R., Kaliszek A. i wsp. Expression of cyclooxygenase-2 in astrocytes of human brain after global ischemia. Folia Neuropathol 1999; 37: 75-79.
-
(1999)
Folia Neuropathol
, vol.37
, pp. 75-79
-
-
Maślińska, D.1
Woźniak, R.2
Kaliszek, A.3
-
51
-
-
0032969529
-
Expression of COX-2 by normal and reactive astrocytes in the adult rat central nervous system
-
i wsp.
-
Hirst W.D., Young K.A., Newton R. i wsp. Expression of COX-2 by normal and reactive astrocytes in the adult rat central nervous system. Mol Cell Neurosci 1999; 13: 57-68.
-
(1999)
Mol Cell Neurosci
, vol.13
, pp. 57-68
-
-
Hirst, W.D.1
Young, K.A.2
Newton, R.3
-
52
-
-
0032896588
-
Cyclooxygenase-2: Molecular biology, pharmacology, and neurobiology
-
O'Banion M.K. Cyclooxygenase-2: molecular biology, pharmacology, and neurobiology. Crit Rev Neurobiol 1999; 13: 45-82.
-
(1999)
Crit Rev Neurobiol
, vol.13
, pp. 45-82
-
-
O'Banion, M.K.1
-
53
-
-
33646117738
-
Amyloid beta peptide (25-35) activates protein kinase C leading to cyclooxygenase-2 induction and prostaglandin E2 release in primary midbrain astrocytes
-
i wsp.
-
Hüll M., Müksch B., Akundi R.S. i wsp. Amyloid beta peptide (25-35) activates protein kinase C leading to cyclooxygenase-2 induction and prostaglandin E2 release in primary midbrain astrocytes. Neurochem Int 2006; 48: 663-672.
-
(2006)
Neurochem Int
, vol.48
, pp. 663-672
-
-
Hüll, M.1
Müksch, B.2
Akundi, R.S.3
-
54
-
-
0032518514
-
Prostaglandins stimulate calcium-dependent glutamate release in astrocytes
-
i wsp.
-
Bezzi P., Carmignoto G., Pasti L. i wsp. Prostaglandins stimulate calcium-dependent glutamate release in astrocytes. Nature 1998; 391: 281-285.
-
(1998)
Nature
, vol.391
, pp. 281-285
-
-
Bezzi, P.1
Carmignoto, G.2
Pasti, L.3
-
55
-
-
0035970036
-
Reduced susceptibility to ischemic brain injury and N-methyl-D-aspartate- mediated neurotoxicity in cyclooxygenase-2-deficient mice
-
DOI 10.1073/pnas.98.3.1294
-
Iadecola C., Niwa K., Nogawa S. i wsp. Reduced susceptibility to ischemic brain injury and N-methyl-D-aspartate-mediated neurotoxicity in cyclooxygenase-2-deficient mice. Proc Natl Acad Sci U S A 2001; 98: 1294-1299. (Pubitemid 32121226)
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, Issue.3
, pp. 1294-1299
-
-
Iadecola, C.1
Niwa, K.2
Nogawa, S.3
Zhao, X.4
Nagayama, M.5
Araki, E.6
Morham, S.7
Ross, M.E.8
-
56
-
-
0035205852
-
Increased susceptibility to ischemic brain injury in cyclooxygenase-1- deficient mice
-
Iadecola C., Sugimoto K., Niwa K. i wsp. Increased susceptibility to ischemic brain injury in cyclooxygenase-1-deficient mice. J Cereb Blood Flow Metab 2001; 21: 1436-1441. (Pubitemid 33117184)
-
(2001)
Journal of Cerebral Blood Flow and Metabolism
, vol.21
, Issue.12
, pp. 1436-1441
-
-
Iadecola, C.1
Sugimoto, K.2
Niwa, K.3
Kazama, K.4
Ross, M.E.5
-
58
-
-
0035653648
-
Central and peripheral roles of prostaglandins in pain and their interactions with novel neuropeptides nociceptin and nocistatin
-
PII S0168010201002899
-
Ito S., Okuda-Ashitaka E., Minami T. Central and peripheral roles of prostaglandins in pain and their interactions with novel neuropeptides nociceptin and nocistatin. Neurosci Res 2001; 41: 299-332. (Pubitemid 33733750)
-
(2001)
Neuroscience Research
, vol.41
, Issue.4
, pp. 299-332
-
-
Ito, S.1
Okuda-Ashitaka, E.2
Minami, T.3
-
59
-
-
0030787985
-
Involvement of cyclooxygenase-2 in LPS-induced fever and regulation of its mRNA by LPS in the rat brain
-
i wsp.
-
Cao C., Matsumura K., Yamagata K. i wsp. Involvement of cyclooxygenase-2 in LPS-induced fever and regulation of its mRNA by LPS in the rat brain. Am J Physiol 1997; 272: R1712-R1725.
-
(1997)
Am J Physiol
, vol.272
-
-
Cao, C.1
Matsumura, K.2
Yamagata, K.3
-
60
-
-
0035887744
-
Age-dependent cognitive deficits and neuronal apoptosis in cyclooxygenase-2 transgenic mice
-
Andreasson K.I., Savonenko A., Vidensky S. i wsp. Age-dependent cognitive deficits and neuronal apoptosis in cyclooxygenase-2 transgenic mice. J Neurosci 2001; 21: 8198-8209. (Pubitemid 32952775)
-
(2001)
Journal of Neuroscience
, vol.21
, Issue.20
, pp. 8198-8209
-
-
Andreasson, K.I.1
Savonenko, A.2
Vidensky, S.3
Goellner, J.J.4
Zhang, Y.5
Shaffer, A.6
Kaufmann, W.E.7
Worley, P.F.8
Isakson, P.9
Markowska, A.L.10
-
61
-
-
0029811901
-
Arthritis and anti-inflammatory agents as possible protective factors for Alzheimer's disease: A review of 17 epidemiologic studies
-
McGeer P.L., Schulzer M., McGeer E.G. Arthritis and inflammatory agents as possible protective factors for Alzheimer's disease: a review of 17 epidemiological studies. Neurology 1996; 47: 425-432. (Pubitemid 26324038)
-
(1996)
Neurology
, vol.47
, Issue.2
, pp. 425-432
-
-
McGeer, P.L.1
Schulzer, M.2
McGeer, E.G.3
-
62
-
-
0035696257
-
Do NSAIDs prevent Alzheimer's disease? And, if so, why? The epidemiological evidence
-
Zandi P.P., Breitner J.C. Do NSAIDs prevent Alzheimer's disease? And, if so, why? The epidemiological evidence. Neurobiol Aging 2001; 22: 811-817.
-
(2001)
Neurobiol Aging
, vol.22
, pp. 811-817
-
-
Zandi, P.P.1
Breitner, J.C.2
-
63
-
-
0033178889
-
Regional distribution of cyclooxygenase-2 in the hippocampal formation in Alzheimer's disease
-
DOI 10.1002/(SICI)1097-4547(19990801)57:3<295::AID-JNR1>3.0.CO;2-0
-
Ho L., Pieroni C., Winger D. i wsp. Regional distribution of cyclooxygenase-2 in the hippocampal formation in Alzheimer's disease. J Neurosci Res 1999; 57: 295-303. (Pubitemid 29339785)
-
(1999)
Journal of Neuroscience Research
, vol.57
, Issue.3
, pp. 295-303
-
-
Ho, L.1
Pieroni, C.2
Winger, D.3
Purohit, D.P.4
Aisen, P.S.5
Pasinetti, G.M.6
-
64
-
-
0032551633
-
Cyclooxygenase-2 expression is increased in frontal cortex of Alzheimer's disease brain
-
DOI 10.1016/S0306-4522(98)00218-8, PII S0306452298002188
-
Pasinetti G.M., Aisen P.S. Cyclooxygenase-2 expression is increased in frontal cortex of Alzheimer's disease brain. Neuroscience 1998; 87: 319-324. (Pubitemid 28370892)
-
(1998)
Neuroscience
, vol.87
, Issue.2
, pp. 319-324
-
-
Pasinetti, G.M.1
Aisen, P.S.2
-
65
-
-
20444377686
-
Regulation of cyclooxygenase-2 system by interleukin-1beta through mitogen-activated protein kinase signaling pathways: A comparative study of human neuroglioma and neuroblastoma cells
-
Moolwaney A.S., Igwe A.J. Regulation of cyclooxygenase-2 system by interleukin-1beta through mitogen-activated protein kinase signaling pathways: a comparative study of human neuroglioma and neuroblastoma cells. Brain Res Mol Brain Res 2005; 137: 202-212.
-
(2005)
Brain Res Mol Brain Res
, vol.137
, pp. 202-212
-
-
Moolwaney, A.S.1
Igwe, A.J.2
-
66
-
-
19444377638
-
Beta-amyloid-induced apoptosis is associated with cyclooxygenase-2 up-regulation via the mitogen-activated protein kinase-NF-kappaB signaling pathway
-
Jang J.H., Surh Y.J. Beta-amyloid-induced apoptosis is associated with cyclooxygenase-2 up-regulation via the mitogen-activated protein kinase-NF-kappaB signaling pathway. Free Rad Biol Med 2005; 38: 1604-1613.
-
(2005)
Free Rad Biol Med
, vol.38
, pp. 1604-1613
-
-
Jang, J.H.1
Surh, Y.J.2
-
67
-
-
0036323485
-
Cyclin D1 and cyclin e are co-localized with cyclooxygenase 2 (COX-2) in pyramidal neurons in Alzheimer disease temporal cortex
-
i wsp.
-
Hoozemans J.J., Brückner M.K., Rozemuller A.J. i wsp. Cyclin D1 and cyclin E are co-localized with cyclooxygenase 2 (COX-2) in pyramidal neurons in Alzheimer disease temporal cortex. J Neuropathol Exp Neurol 2002; 61: 678-688.
-
(2002)
J Neuropathol Exp Neurol
, vol.61
, pp. 678-688
-
-
Hoozemans, J.J.1
Brückner, M.K.2
Rozemuller, A.J.3
-
68
-
-
0035693794
-
Downregulation of neuronal cyclooxygenase-2 expression in end stage Alzheimer's disease
-
Yermakova A.V., O'Banion M.K. Downregulation of neuronal cyclooxygenase-2 expression in end stage Alzheimer's disease. Neurobiol Aging 2001; 22: 823-836.
-
(2001)
Neurobiol Aging
, vol.22
, pp. 823-836
-
-
Yermakova, A.V.1
O'Banion, M.K.2
-
69
-
-
33644541112
-
Neuroinflammation and regeneration in the early stages of Alzheimer's disease pathology
-
DOI 10.1016/j.ijdevneu.2005.11.001, PII S0736574805001425, Neural Signal Transduction in Health and Disease - Cytokinesd, Mitochondrial Dysfunction and Transport Processes
-
Hoozemans J.J., Veerhuis R., Rozemuller J.M. i wsp. Neuroinflammation and regeneration in the early stages of Alzheimer's disease pathology. Int J Dev Neurosci 2006; 24: 157-165. (Pubitemid 43294622)
-
(2006)
International Journal of Developmental Neuroscience
, vol.24
, Issue.2-3
, pp. 157-165
-
-
Hoozemans, J.J.M.1
Veerhuis, R.2
Rozemuller, J.M.3
Eikelenboom, P.4
-
70
-
-
29644438245
-
2, cognitive decline, and survival in Alzheimer's disease
-
DOI 10.1136/jnnp.2005.063131
-
Combrinck M., Williams J., De Berardinis M.A. i wsp. Levels of CSF prostaglandin E2, cognitive decline and survival in Alzheimer's disease. J Neurol Neurosurg Psychiatry 2006; 77: 85-88. (Pubitemid 43022699)
-
(2006)
Journal of Neurology, Neurosurgery and Psychiatry
, vol.77
, Issue.1
, pp. 85-88
-
-
Combrinck, M.1
Williams, J.2
De Berardinis, M.A.3
Warden, D.4
Puopolo, M.5
Smith, A.D.6
Minghetti, L.7
-
71
-
-
30744441143
-
2 mediates neuronal damage by amyloid-beta or prions which activates microglial cells
-
DOI 10.1016/j.neuropharm.2005.09.008, PII S0028390805003515
-
Bate C., Kempster S., Williams A. Prostaglandin D2 mediates neuronal damage by amyloid-beta or prions which activates microglial cells. Neuropharmacology 2006; 50: 229-237. (Pubitemid 43100008)
-
(2006)
Neuropharmacology
, vol.50
, Issue.2
, pp. 229-237
-
-
Bate, C.1
Kempster, S.2
Williams, A.3
-
72
-
-
17444410014
-
Microglial EP2 as a new target to increase amyloid beta phagocytosis and decrease amyloid beta-induced damage to neurons
-
i wsp.
-
Shie F.S., Montine K.S., Breyer R.M. i wsp. Microglial EP2 as a new target to increase amyloid beta phagocytosis and decrease amyloid beta-induced damage to neurons. Brain Pathol 2005; 15: 134-138.
-
(2005)
Brain Pathol
, vol.15
, pp. 134-138
-
-
Shie, F.S.1
Montine, K.S.2
Breyer, R.M.3
-
73
-
-
0034803271
-
Cyclooxygenase-2 stimulates production of amyloid beta-peptide in neuroblastoma X glioma hybrid NG108-15 cells
-
DOI 10.1006/bbrc.2001.4357
-
Kadoyama K., Takahashi Y., Higashida H. i wsp. Cyclooxygenase-2 stimulates production of amyloid beta-peptide in neuroblastoma x glioma hybrid NG108-15 cells. Biochem Biophys Res Commun 2001; 281: 483-490. (Pubitemid 32928181)
-
(2001)
Biochemical and Biophysical Research Communications
, vol.281
, Issue.2
, pp. 483-490
-
-
Kadoyama, K.1
Takahashi, Y.2
Higashida, H.3
Tanabe, T.4
Yoshimoto, T.5
-
74
-
-
9144219644
-
Cyclooxygenase (COX)-2 and COX-1 Potentiate beta-Amyloid Peptide Generation through Mechanisms That Involve gamma-Secretase Activity
-
DOI 10.1074/jbc.M307699200
-
Qin W., Ho L., Pompl P.N. i wsp. Cyclooxygenase (COX)-2 and COX-1 potentiate beta-amyloid peptide generation through mechanisms that involve gamma-secretase activity. J Biol Chem 2003; 278: 50970-50977. (Pubitemid 38020330)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.51
, pp. 50970-50977
-
-
Qin, W.1
Ho, L.2
Pompl, P.N.3
Peng, Y.4
Zhao, Z.5
Xiang, Z.6
Robakis, N.K.7
Shioi, J.8
Suh, J.9
Pasinetti, G.M.10
-
75
-
-
0036424134
-
Cyclooxygenase-2 promotes amyloid plaque deposition in a mouse model of Alzheimer's disease neuropathology
-
Xiang Z., Ho L., Yemul S. i wsp. Cyclooxygenase-2 promotes amyloid plaque deposition in a mouse model of Alzheimer's disease neuropathology. Gene Expr 2002; 10: 271-278. (Pubitemid 35315389)
-
(2002)
Gene Expression
, vol.10
, Issue.5-6
, pp. 271-278
-
-
Xiang, Z.1
Ho, L.2
Yemul, S.3
Zhao, Z.4
Pompl, P.5
Kelley, K.6
Dang, A.7
Qing, W.8
Teplow, D.9
Pasinetti, G.M.10
-
76
-
-
33746433950
-
Cycloxygenase-2 activity promotes cognitive deficits but not increased amyloid burden in a model of Alzheimer's disease in a sex-dimorphic pattern
-
DOI 10.1016/j.neuroscience.2006.05.001, PII S030645220600621X
-
Melnikova T., Savonenko A., Wang Q. i wsp. Cyclooxygenase-2 activity promotes cognitive deficits but not increased amyloid burden in a model of Alzheimer's disease in a sex-dimorphic pattern. Neuroscience 2006; 141: 1149-1162. (Pubitemid 44128685)
-
(2006)
Neuroscience
, vol.141
, Issue.3
, pp. 1149-1162
-
-
Melnikova, T.1
Savonenko, A.2
Wang, Q.3
Liang, X.4
Hand, T.5
Wu, L.6
Kaufmann, W.E.7
Vehmas, A.8
Andreasson, K.I.9
-
77
-
-
0036227488
-
Cyclooxygenase (COX)-2 and cell cycle activity in a transgenic mouse model of Alzheimer's disease neuropathology
-
DOI 10.1016/S0197-4580(01)00282-2, PII S0197458001002822
-
Xiang Z., Ho L., Valdellon J. i wsp. Cyclooxygenase (COX)-2 and cell cycle activity in a transgenic mouse model of Alzheimer's disease neuropathology. Neurobiol Aging 2002; 23: 327-334. (Pubitemid 34312015)
-
(2002)
Neurobiology of Aging
, vol.23
, Issue.3
, pp. 327-334
-
-
Xiang, Z.1
Ho, L.2
Valdellon, J.3
Borchelt, D.4
Kelley, K.5
Spielman, L.6
Aisen, P.S.7
Pasinetti, G.M.8
-
78
-
-
26444548179
-
Differential effects of COX inhibitors against beta-amyloid-induced neurotoxicity in human neuroblastoma cells
-
DOI 10.1016/j.neuint.2005.06.012, PII S0197018605001853
-
Ferrera P., Arias C. Differential effects of COX inhibitors against beta-amyloid-induced neurotoxicity in human neuroblastoma cells. Neurochem Int 2005; 47: 589-596. (Pubitemid 41437904)
-
(2005)
Neurochemistry International
, vol.47
, Issue.8
, pp. 589-596
-
-
Ferrera, P.1
Arias, C.2
-
79
-
-
0037323054
-
2 pathway in production of reactive oxygen species in Alzheimer's disease
-
DOI 10.1023/A:1022389503105
-
Andersen J.M., Myhre O., Fonnum F. Discussion of the role of the extracellular signal-regulated kinase-phospholipase A2 pathway in production of reactive oxygen species in Alzheimer's disease. Neurochem Res 2003; 28: 319-326. (Pubitemid 36207355)
-
(2003)
Neurochemical Research
, vol.28
, Issue.2
, pp. 319-326
-
-
Andersen, J.M.1
Myhre, O.2
Fonnum, F.3
-
80
-
-
0035013564
-
Brain oxidative stress in animal models of accelerated aging and the age-related neurodegenerative disorders, Alzheimer's disease and Huntington's disease
-
Butterfield D.A., Howard B.J., LaFontaine M.A. Brain oxidative stress in animal models of accelerated aging and the age-related neurodegenerative disorders, Alzheimer's disease and Huntington's disease. Curr Med Chem 2001; 8: 815-828.
-
(2001)
Curr Med Chem
, vol.8
, pp. 815-828
-
-
Butterfield, D.A.1
Howard, B.J.2
LaFontaine, M.A.3
-
81
-
-
2442433807
-
Peroxidase Activity of Cyclooxygenase-2 (COX-2) cross-links beta-amyloid (Abeta) and generates Abeta-COX-2 hetero-oligomers that are increased in Alzheimer's disease
-
i wsp.
-
Nagano S., Huang X., Moir R.D. i wsp. Peroxidase Activity of Cyclooxygenase-2 (COX-2) cross-links beta-amyloid (Abeta) and generates Abeta-COX-2 hetero-oligomers that are increased in Alzheimer's disease. J Biol Chem 2004; 279: 14673-14678.
-
(2004)
J Biol Chem
, vol.279
, pp. 14673-14678
-
-
Nagano, S.1
Huang, X.2
Moir, R.D.3
-
82
-
-
17444365094
-
Cyclooxygenase-dependent lipid-modification of brain proteins
-
i wsp.
-
Boutaud O., Andreasson K.I., Zagol-Ikapitte I. i wsp. Cyclooxygenase-dependent lipid-modification of brain proteins. Brain Pathol 2005; 15: 139-142.
-
(2005)
Brain Pathol
, vol.15
, pp. 139-142
-
-
Boutaud, O.1
Andreasson, K.I.2
Zagol-Ikapitte, I.3
-
83
-
-
23844500606
-
Prostaglandin H (2)-derived adducts of proteins correlate with Alzheimer's disease severity
-
i wsp.
-
Zagol-Ikapitte I., Masterson T.S., Amarnath V. i wsp. Prostaglandin H (2)-derived adducts of proteins correlate with Alzheimer's disease severity. J Neurochem 2005; 94: 1140-1145.
-
(2005)
J Neurochem
, vol.94
, pp. 1140-1145
-
-
Zagol-Ikapitte, I.1
Masterson, T.S.2
Amarnath, V.3
-
84
-
-
0034923671
-
Neuronal apoptosis at the G1/S cell cycle checkpoint
-
Liu D.X., Greene L.A. Neuronal apoptosis at the G1/S cell cycle checkpoint. Cell Tissue Res 2001; 305: 217-228.
-
(2001)
Cell Tissue Res
, vol.305
, pp. 217-228
-
-
Liu, D.X.1
Greene, L.A.2
-
85
-
-
0036231413
-
Role of cyclooxygenase-2 in neuronal cell cycle activity and glutamate-mediated excitotoxicity
-
Mirjany M., Ho L., Pasinetti M.G. Role of cyclooxygenase-2 in neuronal cell cycle activity and glutamate-mediated excitotoxicity. J Pharmacol Exp Ther 2002; 301: 494-499.
-
(2002)
J Pharmacol Exp Ther
, vol.301
, pp. 494-499
-
-
Mirjany, M.1
Ho, L.2
Pasinetti, M.G.3
-
86
-
-
0031661968
-
The cell division cycle and the pathophysiology of Alzheimer's disease
-
Nagy Z., Esiri M.M., Smith A.D. The cell division cycle and the pathophysiology of Alzheimer's disease. Neuroscience 1998; 87: 731-739.
-
(1998)
Neuroscience
, vol.87
, pp. 731-739
-
-
Nagy, Z.1
Esiri, M.M.2
Smith, A.D.3
-
87
-
-
1842576590
-
Neuronal COX-2 expression and phosphorylation of pRb precede p38 MAPK activation and neurofibrillary changes in AD temporal cortex
-
i wsp.
-
Hoozemans J.J., Veerhuis R., Rozemuller A.J. i wsp. Neuronal COX-2 expression and phosphorylation of pRb precede p38 MAPK activation and neurofibrillary changes in AD temporal cortex. Neurobiol Dis 2004; 15: 492-499.
-
(2004)
Neurobiol Dis
, vol.15
, pp. 492-499
-
-
Hoozemans, J.J.1
Veerhuis, R.2
Rozemuller, A.J.3
-
88
-
-
0030000385
-
The role of anti-inflammatory drugs in the prevention and treatment of Alzheimer's disease
-
Breitner J.C. The role of anti-inflammatory drugs in the prevention and treatment of Alzheimer's disease. Annu Rev Med 1996; 47: 401-411.
-
(1996)
Annu Rev Med
, vol.47
, pp. 401-411
-
-
Breitner, J.C.1
-
89
-
-
0038268656
-
Non-steroidal anti-inflammatory drugs and cyclooxygenase in Alzheimer's disease
-
i wsp.
-
Hoozemans J.J., Veerhuis R., Rozemuller A.J. i wsp. Non-steroidal anti-inflammatory drugs and cyclooxygenase in Alzheimer's disease. Curr Drug Targets 2003; 4: 461-468.
-
(2003)
Curr Drug Targets
, vol.4
, pp. 461-468
-
-
Hoozemans, J.J.1
Veerhuis, R.2
Rozemuller, A.J.3
-
90
-
-
0038064189
-
Pharmacologic agents associated with a preventive effect on Alzheimer's disease: A review of the epidemiologic evidence
-
i wsp.
-
in t'Veld B.A., Launer L.J., Breteler M.M. i wsp. Pharmacologic agents associated with a preventive effect on Alzheimer's disease: a review of the epidemiologic evidence. Epidemiol Rev 2002; 24: 248-268.
-
(2002)
Epidemiol Rev
, vol.24
, pp. 248-268
-
-
T'Veld, B.A.1
Launer, L.J.2
Breteler, M.M.3
-
91
-
-
0038375640
-
Effect of non-steroidal anti-inflammatory drugs on risk of Alzheimer's disease: Systematic review and meta-analysis of observational studies
-
Etminan M., Gill S., Samii A. Effect of non-steroidal anti-inflammatory drugs on risk of Alzheimer's disease: systematic review and meta-analysis of observational studies. BMJ 2003; 327: 128.
-
(2003)
BMJ
, vol.327
, pp. 128
-
-
Etminan, M.1
Gill, S.2
Samii, A.3
-
92
-
-
0025332027
-
Antiinflammatory drugs and Alzheimer's disease
-
i wsp.
-
McGeer P.L., McGeer E., Rogers J. i wsp. Antiinflammatory drugs and Alzheimer's disease. Lancet 1990; 335: 1037.
-
(1990)
Lancet
, vol.335
, pp. 1037
-
-
McGeer, P.L.1
McGeer, E.2
Rogers, J.3
-
93
-
-
0036812560
-
From epidemiology to therapeutic trials with anti-inflammatory drugs in Alzheimer's disease: The role of NSAIDs and cyclooxygenase in beta-amyloidosis and clinical dementia
-
Pasinetti G.M. From epidemiology to therapeutic trials with anti-inflammatory drugs in Alzheimer's disease: the role of NSAIDs and cyclooxygenase in beta-amyloidosis and clinical dementia. J Alzheimers Dis 2002; 4: 435-445.
-
(2002)
J Alzheimers Dis
, vol.4
, pp. 435-445
-
-
Pasinetti, G.M.1
-
94
-
-
0029021217
-
Do nonsteroidal anti-inflammatory drugs decrease the risk for Alzheimer's disease? The Rotterdam study
-
i wsp.
-
Andersen K., Launer L.J., Ott A. i wsp. Do nonsteroidal anti-inflammatory drugs decrease the risk for Alzheimer's disease? The Rotterdam study. Neurology 1995; 45: 1441-1445.
-
(1995)
Neurology
, vol.45
, pp. 1441-1445
-
-
Andersen, K.1
Launer, L.J.2
Ott, A.3
-
95
-
-
0035696167
-
Postmortem studies of the effect of anti-inflammatory drugs on Alzheimer-type pathology and associated inflammation
-
Mackenzie I.R. Postmortem studies of the effect of anti-inflammatory drugs on Alzheimer-type pathology and associated inflammation. Neurobiol Aging 2001; 22: 819-822.
-
(2001)
Neurobiol Aging
, vol.22
, pp. 819-822
-
-
Mackenzie, I.R.1
-
96
-
-
0035829592
-
A subset of NSAIDs lower amyloidogenic Abeta42 independently of cyclooxygenase activity
-
i wsp.
-
Weggen S., Eriksen J.L., Das P. i wsp. A subset of NSAIDs lower amyloidogenic Abeta42 independently of cyclooxygenase activity. Nature 2001; 414: 212-216.
-
(2001)
Nature
, vol.414
, pp. 212-216
-
-
Weggen, S.1
Eriksen, J.L.2
Das, P.3
-
97
-
-
85047691727
-
NSAIDs and enantiomers of flurbiprofen target gamma-secretase and lower Abeta42 in vivo
-
i wsp.
-
Eriksen J.L., Sagi S.A., Smith T.E. i wsp. NSAIDs and enantiomers of flurbiprofen target gamma-secretase and lower Abeta42 in vivo. J Clin Invest 2003; 112: 440-449.
-
(2003)
J Clin Invest
, vol.112
, pp. 440-449
-
-
Eriksen, J.L.1
Sagi, S.A.2
Smith, T.E.3
-
98
-
-
0041876229
-
Evidence that non-steroidal anti-inflammatory drugs decrease amyloid beta42 production by direct modulation of gamma-secretase activity
-
i wsp.
-
Weggen S., Eriksen J.L., Sagi S.A. i wsp. Evidence that non-steroidal anti-inflammatory drugs decrease amyloid beta42 production by direct modulation of gamma-secretase activity. J Biol Chem 2003; 278: 31831-31837.
-
(2003)
J Biol Chem
, vol.278
, pp. 31831-31837
-
-
Weggen, S.1
Eriksen, J.L.2
Sagi, S.A.3
-
99
-
-
0242609178
-
Nonsteroidal anti-inflammatory drugs and peroxisome proliferator- activated receptor-gamma agonists modulate immunostimulated processing of amyloid precursor protein through regulation of beta-secretase
-
i wsp.
-
Sastre M., Dewachter I., Landreth G.E. i wsp. Nonsteroidal anti-inflammatory drugs and peroxisome proliferator-activated receptor-gamma agonists modulate immunostimulated processing of amyloid precursor protein through regulation of beta-secretase. J Neurosci 2003; 23: 9796-9804.
-
(2003)
J Neurosci
, vol.23
, pp. 9796-9804
-
-
Sastre, M.1
Dewachter, I.2
Landreth, G.E.3
-
100
-
-
27144513779
-
Non-steroidal anti-inflammatory drugs have anti-amyloidogenic effects for Alzheimer's beta-amyloid fibrils in vitro
-
i wsp.
-
Hirohata M., Ono K., Naiki H. i wsp. Non-steroidal anti-inflammatory drugs have anti-amyloidogenic effects for Alzheimer's beta-amyloid fibrils in vitro. Neuropharmacology 2005; 49: 1088-1099.
-
(2005)
Neuropharmacology
, vol.49
, pp. 1088-1099
-
-
Hirohata, M.1
Ono, K.2
Naiki, H.3
-
101
-
-
0031013395
-
Peroxisome proliferator-activated receptors alpha and gamma are activated by indomethacin and other nonsteroidal anti-inflammatory drugs
-
i wsp.
-
Lehmann J.M., Lenhard J.M., Oliver B.B. i wsp. Peroxisome proliferator-activated receptors alpha and gamma are activated by indomethacin and other nonsteroidal anti-inflammatory drugs. J Biol Chem 1997; 272: 3406-3410.
-
(1997)
J Biol Chem
, vol.272
, pp. 3406-3410
-
-
Lehmann, J.M.1
Lenhard, J.M.2
Oliver, B.B.3
-
102
-
-
0034813586
-
Regulation of beta-amyloid stimulated proinflammatory responses by peroxisome proliferators-activated receptor alpha
-
i wsp.
-
Combs C.K., Bates P., Karlo J.C. i wsp. Regulation of beta-amyloid stimulated proinflammatory responses by peroxisome proliferators-activated receptor alpha. Neurochem Int 2001; 39: 449-457.
-
(2001)
Neurochem Int
, vol.39
, pp. 449-457
-
-
Combs, C.K.1
Bates, P.2
Karlo, J.C.3
-
103
-
-
0028896679
-
Nonsteroidal anti-inflammatory drugs in Alzheimer's disease
-
i wsp.
-
Rich J.B., Rastrusson D.X., Folstein M.F. i wsp. Nonsteroidal anti-inflammatory drugs in Alzheimer's disease. Neurology 1995; 45: 51-55.
-
(1995)
Neurology
, vol.45
, pp. 51-55
-
-
Rich, J.B.1
Rastrusson, D.X.2
Folstein, M.F.3
-
104
-
-
0027268393
-
Clinical trial of indomethacin in Alzheimer's disease
-
i wsp.
-
Rogers J., Kirby L.C., Hempelman S.R. i wsp. Clinical trial of indomethacin in Alzheimer's disease. Neurology 1993; 43: 1609-1611.
-
(1993)
Neurology
, vol.43
, pp. 1609-1611
-
-
Rogers, J.1
Kirby, L.C.2
Hempelman, S.R.3
-
105
-
-
0033551547
-
A double-blind, placebo-controlled trial of diclofenac/misoprostol in Alzheimer's disease
-
i wsp.
-
Scharf S., Mander A., Ugoni A. i wsp. A double-blind, placebo-controlled trial of diclofenac/misoprostol in Alzheimer's disease. Neurology 1999; 53: 197-201.
-
(1999)
Neurology
, vol.53
, pp. 197-201
-
-
Scharf, S.1
Mander, A.2
Ugoni, A.3
-
106
-
-
33749484294
-
Efficacy and safety of MPC-7869 (R-flurbiprofen), a selective Abeta42-lowering agent, in Alzheimer's disease (AD): Results of a 12-month phase 2 trial and i-year follow-on study
-
i wsp.
-
Wilcock G.K., Black S.E., Haworth J. i wsp. Efficacy and safety of MPC-7869 (R-flurbiprofen), a selective Abeta42-lowering agent, in Alzheimer's disease (AD): Results of a 12-month phase 2 trial and i-year follow-on study. Alzheimers Dement 2006; 2: S81-S82.
-
(2006)
Alzheimers Dement
, vol.2
-
-
Wilcock, G.K.1
Black, S.E.2
Haworth, J.3
-
107
-
-
0037638809
-
Effects of rofecoxib or naproxen vs placebo on Alzheimer disease progression: A randomized controlled trial
-
i wsp.
-
Aisen P.S., Schafer K.A., Grundman M. i wsp. Effects of rofecoxib or naproxen vs placebo on Alzheimer disease progression: a randomized controlled trial. JAMA 2003; 289: 2819-2826.
-
(2003)
JAMA
, vol.289
, pp. 2819-2826
-
-
Aisen, P.S.1
Schafer, K.A.2
Grundman, M.3
-
108
-
-
33845803191
-
Long-term efficacy and safety of celecoxib in Alzheimer's disease
-
i wsp.
-
Soininen H., West C., Robbins J. i wsp. Long-term efficacy and safety of celecoxib in Alzheimer's disease. Dement Geriatr Cogn Disord 2007; 23: 8-21.
-
(2007)
Dement Geriatr Cogn Disord
, vol.23
, pp. 8-21
-
-
Soininen, H.1
West, C.2
Robbins, J.3
-
109
-
-
0034620538
-
A randomized controlled trial of prednisone in Alzheimer's disease
-
i wsp.
-
Aisen P.S., Davis K.L., Berg J.D. i wsp. A randomized controlled trial of prednisone in Alzheimer's disease. Neurology 2000; 54: 588-593.
-
(2000)
Neurology
, vol.54
, pp. 588-593
-
-
Aisen, P.S.1
Davis, K.L.2
Berg, J.D.3
-
110
-
-
32044463387
-
Coxibs and Alzheimer's disease: Should they stay or should they go
-
Firuzi O., Praticò D. Coxibs and Alzheimer's disease: should they stay or should they go. Ann Neurol 2006; 59: 219-228.
-
(2006)
Ann Neurol
, vol.59
, pp. 219-228
-
-
Firuzi, O.1
Praticò, D.2
-
111
-
-
32944466122
-
Is there a future for cyclooxygenase inhibitors in Alzheimer's disease?
-
i wsp.
-
Ho L., Qin W., Stetka B.S. i wsp. Is there a future for cyclooxygenase inhibitors in Alzheimer's disease? CNS Drugs 2006; 20: 85-98.
-
(2006)
CNS Drugs
, vol.20
, pp. 85-98
-
-
Ho, L.1
Qin, W.2
Stetka, B.S.3
-
112
-
-
33845702374
-
Risk of cardiovascular events in patients receiving celecoxib: A meta-analysis of randomized clinical trials
-
i wsp.
-
White W.B., West C.R., Borer J.S. i wsp. Risk of cardiovascular events in patients receiving celecoxib: a meta-analysis of randomized clinical trials. Am J Cardiol 2007; 99: 91-98.
-
(2007)
Am J Cardiol
, vol.99
, pp. 91-98
-
-
White, W.B.1
West, C.R.2
Borer, J.S.3
-
113
-
-
33845865385
-
Cardiovascular events in clinical trials involving over 41,000 patients evaluating the cyclooxygenase-2 inhibitor celecoxib
-
i wsp.
-
White W.B., Borer J.S., Gorelick P.B. i wsp. Cardiovascular events in clinical trials involving over 41,000 patients evaluating the cyclooxygenase-2 inhibitor celecoxib. Ann Rheum Dis 2006; 65: 411-417.
-
(2006)
Ann Rheum Dis
, vol.65
, pp. 411-417
-
-
White, W.B.1
Borer, J.S.2
Gorelick, P.B.3
-
114
-
-
33751378367
-
Do selective COX-2 inhibitors increase the risk of cerebrovascular events? A meta-analysis of randomized controlled trials
-
Chen L.C., Ashcroft D.M. Do selective COX-2 inhibitors increase the risk of cerebrovascular events? A meta-analysis of randomized controlled trials. J Clin Pharm Ther 2006; 31: 565-576.
-
(2006)
J Clin Pharm Ther
, vol.31
, pp. 565-576
-
-
Chen, L.C.1
Ashcroft, D.M.2
-
115
-
-
33745921486
-
Meta-analysis: Cardiovascular events associated with nonsteroidal anti-inflammatory drugs
-
i wsp.
-
Salpeter S.R., Gregor P., Ormiston T.M. i wsp. Meta-analysis: cardiovascular events associated with nonsteroidal anti-inflammatory drugs. Am J Med 2006; 119: 552-559.
-
(2006)
Am J Med
, vol.119
, pp. 552-559
-
-
Salpeter, S.R.1
Gregor, P.2
Ormiston, T.M.3
-
116
-
-
0037067048
-
Peripheral infection evokes exaggerated sickness behaviour in pre-clinical murine prion disease
-
Combrinck M.I., Perry V.H., Cunningham C. Peripheral infection evokes exaggerated sickness behaviour in pre-clinical murine prion disease. Neuroscience 2002; 112: 7-11.
-
(2002)
Neuroscience
, vol.112
, pp. 7-11
-
-
Combrinck, M.I.1
Perry, V.H.2
Cunningham, C.3
-
117
-
-
0038354036
-
Systemic infection, interleukin 1beta, and cognitive decline in Alzheimer's disease
-
i wsp.
-
Holmes C., El-Okl M., Williams A.L. i wsp. Systemic infection, interleukin 1beta, and cognitive decline in Alzheimer's disease. J Neurol Neurosurg Psychiatry 2003; 74: 788-789.
-
(2003)
J Neurol Neurosurg Psychiatry
, vol.74
, pp. 788-789
-
-
Holmes, C.1
El-Okl, M.2
Williams, A.L.3
-
118
-
-
34250784090
-
Inhibitor of cyclooxygenase-2 protects against amyloid beta peptide-evoked memory impairment in mice
-
Cakała M., Malik A.R., Strosznajder J.B. Inhibitor of cyclooxygenase-2 protects against amyloid beta peptide-evoked memory impairment in mice. Pharmacol Rep 2007; 59: 164-172.
-
(2007)
Pharmacol Rep
, vol.59
, pp. 164-172
-
-
Cakała, M.1
Malik, A.R.2
Strosznajder, J.B.3
-
119
-
-
32244432739
-
Prostaglandin E2 EP1 receptors: Downstream effectors of COX-2 neurotoxicity
-
i wsp.
-
Kawano T., Anrather J., Zhou P. i wsp. Prostaglandin E2 EP1 receptors: downstream effectors of COX-2 neurotoxicity. Nat Med 2006; 12: 225-229.
-
(2006)
Nat Med
, vol.12
, pp. 225-229
-
-
Kawano, T.1
Anrather, J.2
Zhou, P.3
-
120
-
-
36349029592
-
Involvement of prostaglandin E2 in production of amyloid-beta peptides both in vitro and in vivo
-
i wsp.
-
Hoshino T, Nakaya T, Homan T. i wsp. Involvement of prostaglandin E2 in production of amyloid-beta peptides both in vitro and in vivo. J Biol Chem 2007; 282: 32676-32688.
-
(2007)
J Biol Chem
, vol.282
, pp. 32676-32688
-
-
Hoshino, T.1
Nakaya, T.2
Homan, T.3
-
121
-
-
39749188810
-
Cyclooxygenase-2 inhibition improves amyloid-beta-mediated suppression of memory and synaptic plasticity
-
i wsp.
-
Kotilinek L.A., Westerman M.A., Wang Q. i wsp. Cyclooxygenase-2 inhibition improves amyloid-beta-mediated suppression of memory and synaptic plasticity. Brain 2008; 131: 651-664.
-
(2008)
Brain
, vol.131
, pp. 651-664
-
-
Kotilinek, L.A.1
Westerman, M.A.2
Wang, Q.3
|