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Volumn 1, Issue 1, 2009, Pages 73-88

Systems analysis of bone

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL; BONE; FRACTURE; GENETIC VARIABILITY; GENETICS; HUMAN; MOUSE; OSTEOPOROSIS; PHYSIOLOGY; QUANTITATIVE TRAIT LOCUS; REVIEW; RISK FACTOR; SYSTEMS BIOLOGY;

EID: 77951252508     PISSN: 19395094     EISSN: 1939005X     Source Type: Journal    
DOI: 10.1002/wsbm.15     Document Type: Review
Times cited : (39)

References (154)
  • 3
    • 0034285013 scopus 로고    scopus 로고
    • The osteoblast: a sophisticated fibroblast under central surveillance
    • Ducy P, Schinke T, Karsenty G. The osteoblast: a sophisticated fibroblast under central surveillance. Science 2000, 289:1501-1504.
    • (2000) Science , vol.289 , pp. 1501-1504
    • Ducy, P.1    Schinke, T.2    Karsenty, G.3
  • 4
    • 0034284970 scopus 로고    scopus 로고
    • Bone resorption by osteoclasts
    • Teitelbaum SL. Bone resorption by osteoclasts. Science 2000, 289:1504-1508.
    • (2000) Science , vol.289 , pp. 1504-1508
    • Teitelbaum, S.L.1
  • 5
    • 0031672985 scopus 로고    scopus 로고
    • Family history and risk of osteoporotic fracture. Study of Osteoporotic Fractures Research Group
    • Fox KM, Cummings SR, Powell-Threets K, Stone K. Family history and risk of osteoporotic fracture. Study of Osteoporotic Fractures Research Group. Osteoporos Int 1998, 8:557-562.
    • (1998) Osteoporos Int , vol.8 , pp. 557-562
    • Fox, K.M.1    Cummings, S.R.2    Powell-Threets, K.3    Stone, K.4
  • 6
    • 0023514137 scopus 로고
    • Genetic determinants of bone mineral content at the spine and radius: a twin study
    • Dequeker J, Nijs J, Verstraeten A, Geusens P, Gevers G. Genetic determinants of bone mineral content at the spine and radius: a twin study. Bone 1987, 8:207-209.
    • (1987) Bone , vol.8 , pp. 207-209
    • Dequeker, J.1    Nijs, J.2    Verstraeten, A.3    Geusens, P.4    Gevers, G.5
  • 7
    • 0028834048 scopus 로고
    • Environmental and genetic factors affecting bone mass. Similarity of bone density among members of healthy families
    • Jouanny P, Guillemin F, Kuntz C, Jeandel C, Pourel J. Environmental and genetic factors affecting bone mass. Similarity of bone density among members of healthy families. Arthritis Rheum 1995, 38:61-67.
    • (1995) Arthritis Rheum , vol.38 , pp. 61-67
    • Jouanny, P.1    Guillemin, F.2    Kuntz, C.3    Jeandel, C.4    Pourel, J.5
  • 8
    • 0035193086 scopus 로고    scopus 로고
    • Familial resemblance of bone mineral density between females 18 years and older and their mothers
    • Picard D, Imbach A, Couturier M, Lepage R, Picard M. Familial resemblance of bone mineral density between females 18 years and older and their mothers. Can J Public Health 2001, 92:353-358.
    • (2001) Can J Public Health , vol.92 , pp. 353-358
    • Picard, D.1    Imbach, A.2    Couturier, M.3    Lepage, R.4    Picard, M.5
  • 10
    • 0025812532 scopus 로고
    • Genetic determinants of bone mass in adult women: a reevaluation of the twin model and the potential importance of gene interaction on heritability estimates
    • Slemenda CW, Christian JC, Williams CJ, Norton JA, Johnston CC Jr. Genetic determinants of bone mass in adult women: a reevaluation of the twin model and the potential importance of gene interaction on heritability estimates. J Bone Miner Res 1991, 6:561-567.
    • (1991) J Bone Miner Res , vol.6 , pp. 561-567
    • Slemenda, C.W.1    Christian, J.C.2    Williams, C.J.3    Norton, J.A.4    Johnston C.C., Jr.5
  • 11
    • 0024440244 scopus 로고
    • Familial resemblance of radial bone mass between premenopausal mothers and their college-age daughters
    • Tylavsky FA, Bortz AD, Hancock RL, Anderson JJ. Familial resemblance of radial bone mass between premenopausal mothers and their college-age daughters. Calcif Tissue Int 1989, 45:265-272.
    • (1989) Calcif Tissue Int , vol.45 , pp. 265-272
    • Tylavsky, F.A.1    Bortz, A.D.2    Hancock, R.L.3    Anderson, J.J.4
  • 13
    • 0028866916 scopus 로고
    • Segregation analysis and variance components analysis of bone mineral density in healthy families
    • Gueguen R, Jouanny P, Guillemin F, Kuntz C, Pourel J, et al. Segregation analysis and variance components analysis of bone mineral density in healthy families. J Bone Miner Res 1995, 10:2017-2022.
    • (1995) J Bone Miner Res , vol.10 , pp. 2017-2022
    • Gueguen, R.1    Jouanny, P.2    Guillemin, F.3    Kuntz, C.4    Pourel, J.5
  • 14
    • 0031300572 scopus 로고    scopus 로고
    • Family correlations of metacarpal bones-heritable (h2) and environmental (c2) components of total phenotypic variation
    • Skaric-Juric T, Rudan P. Family correlations of metacarpal bones-heritable (h2) and environmental (c2) components of total phenotypic variation. Coll Antropol 1997, 21:447-459.
    • (1997) Coll Antropol , vol.21 , pp. 447-459
    • Skaric-Juric, T.1    Rudan, P.2
  • 15
    • 9744236728 scopus 로고    scopus 로고
    • The estimation of the heritability of anthropometric measurements
    • Chatterjee S, Das N, Chatterjee P. The estimation of the heritability of anthropometric measurements. Appl Human Sci 1999, 18:1-7.
    • (1999) Appl Human Sci , vol.18 , pp. 1-7
    • Chatterjee, S.1    Das, N.2    Chatterjee, P.3
  • 17
    • 0032940465 scopus 로고    scopus 로고
    • Familial resemblance of bone mineral density (BMD) and calcaneal ultrasound attenuation: the BMD in mothers and daughters study
    • Danielson ME, Cauley JA, Baker CE, Newman AB, Dorman JS, et al. Familial resemblance of bone mineral density (BMD) and calcaneal ultrasound attenuation: the BMD in mothers and daughters study. J Bone Miner Res 1999, 14:102-110.
    • (1999) J Bone Miner Res , vol.14 , pp. 102-110
    • Danielson, M.E.1    Cauley, J.A.2    Baker, C.E.3    Newman, A.B.4    Dorman, J.S.5
  • 19
    • 0345832223 scopus 로고    scopus 로고
    • Evidence for a major gene underlying bone size variation in the Chinese
    • Liu PY, Qin YJ, Recker RR, Deng HW. Evidence for a major gene underlying bone size variation in the Chinese. Am J Hum Biol 2004, 16:68-77.
    • (2004) Am J Hum Biol , vol.16 , pp. 68-77
    • Liu, P.Y.1    Qin, Y.J.2    Recker, R.R.3    Deng, H.W.4
  • 20
    • 0037291877 scopus 로고    scopus 로고
    • Quantitative genetic study of radiographic hand bone size and geometry
    • Livshits G, Yakovenko K, Kobyliansky E. Quantitative genetic study of radiographic hand bone size and geometry. Bone 2003, 32:191-198.
    • (2003) Bone , vol.32 , pp. 191-198
    • Livshits, G.1    Yakovenko, K.2    Kobyliansky, E.3
  • 22
    • 0025550302 scopus 로고
    • Chronological changes in genetic variance and heritability of anthropometric characteristics among Chinese twin infants
    • Chen CJ, Yu MW, Wang CJ, Tong SL, Tien M, et al. Chronological changes in genetic variance and heritability of anthropometric characteristics among Chinese twin infants. Acta Genet Med Gemellol (Roma) 1990, 39:479-484.
    • (1990) Acta Genet Med Gemellol (Roma) , vol.39 , pp. 479-484
    • Chen, C.J.1    Yu, M.W.2    Wang, C.J.3    Tong, S.L.4    Tien, M.5
  • 24
    • 0029880429 scopus 로고    scopus 로고
    • Do genetic factors explain associations between muscle strength, lean mass, and bone density? A twin study
    • Seeman E, Hopper JL, Young NR, Formica C, Goss P, et al. Do genetic factors explain associations between muscle strength, lean mass, and bone density? A twin study. Am J Physiol 1996, 270:E320-E327.
    • (1996) Am J Physiol , vol.270
    • Seeman, E.1    Hopper, J.L.2    Young, N.R.3    Formica, C.4    Goss, P.5
  • 26
    • 0027175806 scopus 로고
    • Basic biomechanical measurements of bone: a tutorial
    • Turner CH, Burr DB. Basic biomechanical measurements of bone: a tutorial. Bone 1993, 14:595-608.
    • (1993) Bone , vol.14 , pp. 595-608
    • Turner, C.H.1    Burr, D.B.2
  • 29
    • 84985407437 scopus 로고
    • The thickness of the walls of tubular bones
    • Currey JD, Alexander RM. The thickness of the walls of tubular bones. J Zool 1985, 206:453-468.
    • (1985) J Zool , vol.206 , pp. 453-468
    • Currey, J.D.1    Alexander, R.M.2
  • 30
    • 0018772959 scopus 로고
    • Mechanical properties of bone tissues with greatly differing functions
    • Currey JD. Mechanical properties of bone tissues with greatly differing functions. J Biomech 1979, 12:313-319.
    • (1979) J Biomech , vol.12 , pp. 313-319
    • Currey, J.D.1
  • 31
    • 0030453290 scopus 로고    scopus 로고
    • Ontogenetic and anatomic variation in mineralization of the wing skeleton of theMexican free-tailed bat, Tadarida brasiliensis
    • Papadimitriou HM, Swartz SM, Kunz TH. Ontogenetic and anatomic variation in mineralization of the wing skeleton of theMexican free-tailed bat, Tadarida brasiliensis. J Zool 1996, 240:411-426.
    • (1996) J Zool , vol.240 , pp. 411-426
    • Papadimitriou, H.M.1    Swartz, S.M.2    Kunz, T.H.3
  • 32
    • 0037146578 scopus 로고    scopus 로고
    • Finding genes that underlie complex traits
    • Glazier AM, Nadeau JH, Aitman TJ. Finding genes that underlie complex traits. Science 2002, 298:2345-2349.
    • (2002) Science , vol.298 , pp. 2345-2349
    • Glazier, A.M.1    Nadeau, J.H.2    Aitman, T.J.3
  • 33
    • 17844411239 scopus 로고    scopus 로고
    • Genetic approaches to studying common diseases and complex traits
    • Hirschhorn JN. Genetic approaches to studying common diseases and complex traits. Pediatr Res 2005, 57:74R-77R.
    • (2005) Pediatr Res , vol.57
    • Hirschhorn, J.N.1
  • 34
    • 0029068641 scopus 로고
    • Genetic dissection of inflammatory responses
    • Nadeau JH, Arbuckle LD, Skamene E. Genetic dissection of inflammatory responses. J Inflamm 1995, 45:27-48.
    • (1995) J Inflamm , vol.45 , pp. 27-48
    • Nadeau, J.H.1    Arbuckle, L.D.2    Skamene, E.3
  • 35
    • 0035188787 scopus 로고    scopus 로고
    • Defining the genetics of osteoporosis: using the mouse to understand man
    • Rosen CJ, Beamer WG, Donahue LR. Defining the genetics of osteoporosis: using the mouse to understand man. Osteoporos Int 2001, 12:803-810.
    • (2001) Osteoporos Int , vol.12 , pp. 803-810
    • Rosen, C.J.1    Beamer, W.G.2    Donahue, L.R.3
  • 36
    • 13144265739 scopus 로고    scopus 로고
    • Genome-wide association studies: theoretical and practical concerns
    • Wang WY, Barratt BJ, Clayton DG, Todd JA. Genome-wide association studies: theoretical and practical concerns. Nat Rev Genet 2005, 6:109-118.
    • (2005) Nat Rev Genet , vol.6 , pp. 109-118
    • Wang, W.Y.1    Barratt, B.J.2    Clayton, D.G.3    Todd, J.A.4
  • 37
    • 0036138175 scopus 로고    scopus 로고
    • A mutation in the LDL receptorrelated protein 5 gene results in the autosomal dominant high-bone-mass trait
    • Little RD, Carulli JP, Del Mastro RG, Dupuis J, Osborne M, et al. A mutation in the LDL receptorrelated protein 5 gene results in the autosomal dominant high-bone-mass trait. Am J Hum Genet 2002, 70:11-19.
    • (2002) Am J Hum Genet , vol.70 , pp. 11-19
    • Little, R.D.1    Carulli, J.P.2    Del Mastro, R.G.3    Dupuis, J.4    Osborne, M.5
  • 38
    • 9144272249 scopus 로고    scopus 로고
    • Regulation of bone mass in mice by the lipoxygenase gene Alox15
    • Klein RF, Allard J, Avnur Z, Nikolcheva T, Rotstein D, et al. Regulation of bone mass in mice by the lipoxygenase gene Alox15. Science 2004, 303:229-232.
    • (2004) Science , vol.303 , pp. 229-232
    • Klein, R.F.1    Allard, J.2    Avnur, Z.3    Nikolcheva, T.4    Rotstein, D.5
  • 39
    • 34248172950 scopus 로고    scopus 로고
    • Identification of mouse Duffy antigen receptor for chemokines (Darc) as a BMD QTL gene
    • Edderkaoui B, Baylink DJ, Beamer WG, Wergedal JE, Porte R, et al. Identification of mouse Duffy antigen receptor for chemokines (Darc) as a BMD QTL gene. Genome Res 2007, 17:577-585.
    • (2007) Genome Res , vol.17 , pp. 577-585
    • Edderkaoui, B.1    Baylink, D.J.2    Beamer, W.G.3    Wergedal, J.E.4    Porte, R.5
  • 41
    • 0029880186 scopus 로고    scopus 로고
    • Genetic variability in adult bone density among inbred strains of mice
    • Beamer WG, Donahue LR, Rosen CJ, Baylink DJ. Genetic variability in adult bone density among inbred strains of mice. Bone 1996, 18:397-403.
    • (1996) Bone , vol.18 , pp. 397-403
    • Beamer, W.G.1    Donahue, L.R.2    Rosen, C.J.3    Baylink, D.J.4
  • 42
    • 0029922240 scopus 로고    scopus 로고
    • The heritability of bone mineral density, ultrasound of the calcaneus and hip axis length: a study of postmenopausal twins
    • Arden NK, Baker J, Hogg C, Baan K, Spector TD. The heritability of bone mineral density, ultrasound of the calcaneus and hip axis length: a study of postmenopausal twins. J Bone Miner Res 1996, 11:530-534.
    • (1996) J Bone Miner Res , vol.11 , pp. 530-534
    • Arden, N.K.1    Baker, J.2    Hogg, C.3    Baan, K.4    Spector, T.D.5
  • 43
  • 44
    • 0034968388 scopus 로고    scopus 로고
    • Quantitative trait loci for femoral and lumbar vertebral bone mineral density in C57BL/6J and C3H/HeJ inbred strains of mice
    • Beamer WG, Shultz KL, Donahue LR, Churchill GA, Sen S, et al. Quantitative trait loci for femoral and lumbar vertebral bone mineral density in C57BL/6J and C3H/HeJ inbred strains of mice. J Bone Miner Res 2001, 16:1195-1206.
    • (2001) J Bone Miner Res , vol.16 , pp. 1195-1206
    • Beamer, W.G.1    Shultz, K.L.2    Donahue, L.R.3    Churchill, G.A.4    Sen, S.5
  • 45
    • 0034021980 scopus 로고    scopus 로고
    • Chromosomal mapping of osteopenia-associated quantitative trait loci using closely related mouse strains
    • BenesH, Weinstein RS, Zheng W, Thaden JJ, Jilka RL, et al.Chromosomal mapping of osteopenia-associated quantitative trait loci using closely related mouse strains. J Bone Miner Res 2000, 15:626-633.
    • (2000) J Bone Miner Res , vol.15 , pp. 626-633
    • Benes, H.1    Weinstein, R.S.2    Zheng, W.3    Thaden, J.J.4    Jilka, R.L.5
  • 46
    • 0036129838 scopus 로고    scopus 로고
    • Generation of a new congenic mouse strain to test the relationships among serum insulin-like growth factor I, bone mineral density, and skeletal morphology in vivo
    • Bouxsein ML, Rosen CJ, Turner CH, Ackert CL, Shultz KL, et al. Generation of a new congenic mouse strain to test the relationships among serum insulin-like growth factor I, bone mineral density, and skeletal morphology in vivo. J Bone Miner Res 2002, 17:570-579.
    • (2002) J Bone Miner Res , vol.17 , pp. 570-579
    • Bouxsein, M.L.1    Rosen, C.J.2    Turner, C.H.3    Ackert, C.L.4    Shultz, K.L.5
  • 47
    • 0345876776 scopus 로고    scopus 로고
    • Genetic loci determining bone density in mice with diet-induced atherosclerosis
    • Drake TA, Schadt E, Hannani K, Kabo JM, Krass K, et al. Genetic loci determining bone density in mice with diet-induced atherosclerosis. Physiol Genomics 2001, 5:205-215.
    • (2001) Physiol Genomics , vol.5 , pp. 205-215
    • Drake, T.A.1    Schadt, E.2    Hannani, K.3    Kabo, J.M.4    Krass, K.5
  • 48
    • 21244473273 scopus 로고    scopus 로고
    • Fine mapping of a QTL region with large effects on growth and fatness on mouse chromosome 2
    • Jerez-Timaure NC, Eisen EJ, Pomp D. Fine mapping of a QTL region with large effects on growth and fatness on mouse chromosome 2. Physiol Genomics 2005, 21:411-422.
    • (2005) Physiol Genomics , vol.21 , pp. 411-422
    • Jerez-Timaure, N.C.1    Eisen, E.J.2    Pomp, D.3
  • 50
    • 0036786235 scopus 로고    scopus 로고
    • Mapping quantitative trait loci that influence femoral cross-sectional area in mice
    • Klein RF, Turner RJ, Skinner LD, Vartanian KA, Serang M, et al. Mapping quantitative trait loci that influence femoral cross-sectional area in mice. J Bone Miner Res 2002, 17:1752-1760.
    • (2002) J Bone Miner Res , vol.17 , pp. 1752-1760
    • Klein, R.F.1    Turner, R.J.2    Skinner, L.D.3    Vartanian, K.A.4    Serang, M.5
  • 51
    • 0142179020 scopus 로고    scopus 로고
    • Genetic effects for femoral biomechanics, structure, and density in C57BL/6J and C3H/HeJ inbred mouse strains
    • Koller DL, Schriefer J, Sun Q, Shultz KL, Donahue LR, et al. Genetic effects for femoral biomechanics, structure, and density in C57BL/6J and C3H/HeJ inbred mouse strains. J Bone Miner Res 2003, 18:1758-1765.
    • (2003) J Bone Miner Res , vol.18 , pp. 1758-1765
    • Koller, D.L.1    Schriefer, J.2    Sun, Q.3    Shultz, K.L.4    Donahue, L.R.5
  • 52
    • 0036252133 scopus 로고    scopus 로고
    • Genetic dissection of femur breaking strength in a large population (MRL/MpJ x SJL/J) of F2 Mice: single QTL effects, epistasis, and pleiotropy
    • Li X, Masinde G, Gu W, Wergedal J, Mohan S, et al. Genetic dissection of femur breaking strength in a large population (MRL/MpJ x SJL/J) of F2 Mice: single QTL effects, epistasis, and pleiotropy. Genomics 2002, 79:734-740.
    • (2002) Genomics , vol.79 , pp. 734-740
    • Li, X.1    Masinde, G.2    Gu, W.3    Wergedal, J.4    Mohan, S.5
  • 53
    • 0042665656 scopus 로고    scopus 로고
    • Quantitative trait loci for bone density in mice: the genes determining total skeletal density and femur density show little overlap in F2 mice
    • Masinde GL, Li X, Gu W, Wergedal J, Mohan S, et al. Quantitative trait loci for bone density in mice: the genes determining total skeletal density and femur density show little overlap in F2 mice. Calcif Tissue Int 2002, 71:421-428.
    • (2002) Calcif Tissue Int , vol.71 , pp. 421-428
    • Masinde, G.L.1    Li, X.2    Gu, W.3    Wergedal, J.4    Mohan, S.5
  • 54
    • 35348850141 scopus 로고    scopus 로고
    • Chemical mutagenesis induced two high bone density mouse mutants map to a concordant distal chromosome 4 locus
    • Mohan S, Chest V, Chadwick RB, Wergedal JE, Srivastava AK. Chemical mutagenesis induced two high bone density mouse mutants map to a concordant distal chromosome 4 locus. Bone 2007, 41:860-868.
    • (2007) Bone , vol.41 , pp. 860-868
    • Mohan, S.1    Chest, V.2    Chadwick, R.B.3    Wergedal, J.E.4    Srivastava, A.K.5
  • 55
    • 0034778448 scopus 로고    scopus 로고
    • Gender specificity in the genetic determinants of peak bone mass
    • Orwoll ES, Belknap JK, Klein RF. Gender specificity in the genetic determinants of peak bone mass. J Bone Miner Res 2001, 16:1962-1971.
    • (2001) J Bone Miner Res , vol.16 , pp. 1962-1971
    • Orwoll, E.S.1    Belknap, J.K.2    Klein, R.F.3
  • 56
    • 10744230944 scopus 로고    scopus 로고
    • Congenic mice reveal sex-specific genetic regulation of femoral structure and strength
    • Turner CH, Sun Q, Schriefer J, Pitner N, Price R, et al. Congenic mice reveal sex-specific genetic regulation of femoral structure and strength. Calcif Tissue Int 2003, 73:297-303.
    • (2003) Calcif Tissue Int , vol.73 , pp. 297-303
    • Turner, C.H.1    Sun, Q.2    Schriefer, J.3    Pitner, N.4    Price, R.5
  • 57
    • 33847174964 scopus 로고    scopus 로고
    • Detecting novel bone density and bone size quantitative trait loci using a cross of MRL/MpJ and CAST/EiJ inbred mice
    • Yu H, Mohan S, Edderkaoui B, Masinde GL, Davidson HM, et al. Detecting novel bone density and bone size quantitative trait loci using a cross of MRL/MpJ and CAST/EiJ inbred mice. Calcif Tissue Int 2007, 80:103-110.
    • (2007) Calcif Tissue Int , vol.80 , pp. 103-110
    • Yu, H.1    Mohan, S.2    Edderkaoui, B.3    Masinde, G.L.4    Davidson, H.M.5
  • 58
    • 34547582376 scopus 로고    scopus 로고
    • Genetic regulation of femoral bone mineral density: complexity of sex effect in chromosome 1 revealed by congenic sublines of mice
    • Edderkaoui B, Baylink DJ, Beamer WG, Shultz KL, Wergedal JE, et al. Genetic regulation of femoral bone mineral density: complexity of sex effect in chromosome 1 revealed by congenic sublines of mice. Bone 2007, 41:340-345.
    • (2007) Bone , vol.41 , pp. 340-345
    • Edderkaoui, B.1    Baylink, D.J.2    Beamer, W.G.3    Shultz, K.L.4    Wergedal, J.E.5
  • 59
    • 34548057008 scopus 로고    scopus 로고
    • Genetic dissection of mouse distal chromosome 1 reveals three linked BMD QTLs with sex-dependent regulation of bone phenotypes
    • Beamer WG, Shultz KL, Ackert-Bicknell CL, Horton LG, Delahunty KM, et al. Genetic dissection of mouse distal chromosome 1 reveals three linked BMD QTLs with sex-dependent regulation of bone phenotypes. J Bone Miner Res 2007, 22:1187-1196.
    • (2007) J Bone Miner Res , vol.22 , pp. 1187-1196
    • Beamer, W.G.1    Shultz, K.L.2    Ackert-Bicknell, C.L.3    Horton, L.G.4    Delahunty, K.M.5
  • 61
    • 0034925448 scopus 로고    scopus 로고
    • Genetic loci influencing natural variations in femoral bone morphometry in mice
    • Drake TA, Hannani K, Kabo JM, Villa V, Krass K, et al. Genetic loci influencing natural variations in femoral bone morphometry in mice. J Orthop Res 2001, 19:511-517.
    • (2001) J Orthop Res , vol.19 , pp. 511-517
    • Drake, T.A.1    Hannani, K.2    Kabo, J.M.3    Villa, V.4    Krass, K.5
  • 63
    • 17644406476 scopus 로고    scopus 로고
    • Quantitative trait loci analysis of structural and material skeletal phenotypes in C57BL/6J and DBA/2 second-generation and recombinant inbred mice
    • Lang DH, Sharkey NA, Mack HA, Vogler GP, Vandenbergh DJ, et al. Quantitative trait loci analysis of structural and material skeletal phenotypes in C57BL/6J and DBA/2 second-generation and recombinant inbred mice. J Bone Miner Res 2005, 20:88-99.
    • (2005) J Bone Miner Res , vol.20 , pp. 88-99
    • Lang, D.H.1    Sharkey, N.A.2    Mack, H.A.3    Vogler, G.P.4    Vandenbergh, D.J.5
  • 64
    • 0037315858 scopus 로고    scopus 로고
    • Evidence for a skeletal mechanosensitivity gene on mouse chromosome 4
    • Robling AG, Li J, Shultz KL, BeamerWG, Turner CH. Evidence for a skeletal mechanosensitivity gene on mouse chromosome 4. FASEB J 2003, 17:324-326.
    • (2003) FASEB J , vol.17 , pp. 324-326
    • Robling, A.G.1    Li, J.2    Shultz, K.L.3    Beamer, W.G.4    Turner, C.H.5
  • 65
    • 0011983514 scopus 로고    scopus 로고
    • Identification of peak bone mass QTL in a spontaneously osteoporotic mouse strain
    • Shimizu M, Higuchi K, Bennett B, Xia C, Tsuboyama T, et al. Identification of peak bone mass QTL in a spontaneously osteoporotic mouse strain. Mamm Genome 1999, 10:81-87.
    • (1999) Mamm Genome , vol.10 , pp. 81-87
    • Shimizu, M.1    Higuchi, K.2    Bennett, B.3    Xia, C.4    Tsuboyama, T.5
  • 66
    • 0242607246 scopus 로고    scopus 로고
    • Quantitative trait loci for femoral size and shape in a genetically heterogeneous mouse population
    • Volkman SK, Galecki AT, Burke DT, Paczas MR, Moalli MR, et al. Quantitative trait loci for femoral size and shape in a genetically heterogeneous mouse population. J Bone Miner Res 2003, 18:1497-1505.
    • (2003) J Bone Miner Res , vol.18 , pp. 1497-1505
    • Volkman, S.K.1    Galecki, A.T.2    Burke, D.T.3    Paczas, M.R.4    Moalli, M.R.5
  • 68
    • 0033233166 scopus 로고    scopus 로고
    • Growing C57Bl/6 mice increase whole bone mechanical properties by increasing geometric and material properties
    • BrodtMD, Ellis CB, SilvaMJ. Growing C57Bl/6 mice increase whole bone mechanical properties by increasing geometric and material properties. J Bone Miner Res 1999, 14:2159-2166.
    • (1999) J Bone Miner Res , vol.14 , pp. 2159-2166
    • Brodt, M.D.1    Ellis, C.B.2    Silva, M.J.3
  • 69
    • 16644381419 scopus 로고    scopus 로고
    • Quantitative trait loci that modulate femoral mechanical properties in a genetically heterogeneous mouse population
    • Volkman SK, Galecki AT, Burke DT, Miller RA, Goldstein SA. Quantitative trait loci that modulate femoral mechanical properties in a genetically heterogeneous mouse population. J Bone Miner Res 2004, 19:1497-1505.
    • (2004) J Bone Miner Res , vol.19 , pp. 1497-1505
    • Volkman, S.K.1    Galecki, A.T.2    Burke, D.T.3    Miller, R.A.4    Goldstein, S.A.5
  • 70
    • 34250700440 scopus 로고    scopus 로고
    • Quantitative trait loci that determine mouse tibial nanoindentation properties in an F2 population derived from C57BL/6J x C3H/HeJ
    • Jiao Y, Chiu H, Fan Z, Jiao F, Eckstein EC, et al. Quantitative trait loci that determine mouse tibial nanoindentation properties in an F2 population derived from C57BL/6J x C3H/HeJ. Calcif Tissue Int 2007, 80:383-390.
    • (2007) Calcif Tissue Int , vol.80 , pp. 383-390
    • Jiao, Y.1    Chiu, H.2    Fan, Z.3    Jiao, F.4    Eckstein, E.C.5
  • 73
    • 0036676971 scopus 로고    scopus 로고
    • Genetic predisposition to low bone mass is paralleled by an enhanced sensitivity to signals anabolic to the skeleton
    • Judex S, Donahue LR, Rubin C. Genetic predisposition to low bone mass is paralleled by an enhanced sensitivity to signals anabolic to the skeleton. FASEB J 2002, 16:1280-1282.
    • (2002) FASEB J , vol.16 , pp. 1280-1282
    • Judex, S.1    Donahue, L.R.2    Rubin, C.3
  • 74
    • 34347252968 scopus 로고    scopus 로고
    • Novel loci regulating bone anabolic response to loading: expression QTL analysis in C57BL/6JXC3H/HeJ mice cross
    • Kesavan C, Baylink DJ, Kapoor S, Mohan S. Novel loci regulating bone anabolic response to loading: expression QTL analysis in C57BL/6JXC3H/HeJ mice cross. Bone 2007, 41:223-230.
    • (2007) Bone , vol.41 , pp. 223-230
    • Kesavan, C.1    Baylink, D.J.2    Kapoor, S.3    Mohan, S.4
  • 75
    • 0034807638 scopus 로고    scopus 로고
    • Bone brittleness varies with genetic background in A/J and C57BL/6J inbred mice
    • Jepsen KJ, Pennington DE, Lee YL, Warman M, Nadeau J. Bone brittleness varies with genetic background in A/J and C57BL/6J inbred mice. J Bone Miner Res 2001, 16:1854-1862.
    • (2001) J Bone Miner Res , vol.16 , pp. 1854-1862
    • Jepsen, K.J.1    Pennington, D.E.2    Lee, Y.L.3    Warman, M.4    Nadeau, J.5
  • 77
    • 33746158977 scopus 로고    scopus 로고
    • Developmental integration and the evolution of pleiotropy
    • Cheverud JM. Developmental integration and the evolution of pleiotropy. Am Zool 1996, 36:44-50.
    • (1996) Am Zool , vol.36 , pp. 44-50
    • Cheverud, J.M.1
  • 78
    • 0142184057 scopus 로고    scopus 로고
    • Pleiotropic effects on mandibular morphology I. Developmental morphological integration and differential dominance
    • Ehrich TH, Vaughn TT, Koreishi SF, Linsey RB, Pletscher LS, et al. Pleiotropic effects on mandibular morphology I. Developmental morphological integration and differential dominance. J Exp Zoolog B Mol Dev Evol 2003, 296:58-79.
    • (2003) J Exp Zoolog B Mol Dev Evol , vol.296 , pp. 58-79
    • Ehrich, T.H.1    Vaughn, T.T.2    Koreishi, S.F.3    Linsey, R.B.4    Pletscher, L.S.5
  • 79
    • 0022636594 scopus 로고
    • Genes that affect morphogenesis of the murine mandible: recombinant-inbred strain analysis
    • Bailey DW. Genes that affect morphogenesis of the murine mandible: recombinant-inbred strain analysis. J Hered 1986, 77:17-25.
    • (1986) J Hered , vol.77 , pp. 17-25
    • Bailey, D.W.1
  • 80
    • 0001618604 scopus 로고
    • Phenotypic, genetic, and environmental morphological integration in the cranium
    • Cheverud JM. Phenotypic, genetic, and environmental morphological integration in the cranium. Evolution 1982, 36:499-516.
    • (1982) Evolution , vol.36 , pp. 499-516
    • Cheverud, J.M.1
  • 81
    • 0141564962 scopus 로고    scopus 로고
    • Developmental integration in a complex morphological structure: how distinct are the modules in the mouse mandible?
    • Klingenberg CP, Mebus K, Auffray JC. Developmental integration in a complex morphological structure: how distinct are the modules in the mouse mandible? Evol Dev 2003, 5:522-531.
    • (2003) Evol Dev , vol.5 , pp. 522-531
    • Klingenberg, C.P.1    Mebus, K.2    Auffray, J.C.3
  • 82
    • 7244232837 scopus 로고    scopus 로고
    • Pleiotropic effects on mandibular morphology II: differential epistasis and genetic variation in morphological integration
    • Cheverud JM, Ehrich TH, Vaughn TT, Koreishi SF, Linsey RB, et al. Pleiotropic effects on mandibular morphology II: differential epistasis and genetic variation in morphological integration. J Exp Zoolog B Mol Dev Evol 2004, 302:424-435.
    • (2004) J Exp Zoolog B Mol Dev Evol , vol.302 , pp. 424-435
    • Cheverud, J.M.1    Ehrich, T.H.2    Vaughn, T.T.3    Koreishi, S.F.4    Linsey, R.B.5
  • 83
    • 0033832152 scopus 로고    scopus 로고
    • Is the genotypephenotype map modular? A statistical approach using mouse quantitative trait loci data
    • Mezey JG, Cheverud JM, Wagner GP. Is the genotypephenotype map modular? A statistical approach using mouse quantitative trait loci data. Genetics 2000, 156:305-311.
    • (2000) Genetics , vol.156 , pp. 305-311
    • Mezey, J.G.1    Cheverud, J.M.2    Wagner, G.P.3
  • 84
    • 2442588743 scopus 로고    scopus 로고
    • Integration and modularity of quantitative trait locus effects on geometric shape in the mouse mandible
    • Klingenberg CP, Leamy LJ, Cheverud JM. Integration and modularity of quantitative trait locus effects on geometric shape in the mouse mandible. Genetics 2004, 166:1909-1921.
    • (2004) Genetics , vol.166 , pp. 1909-1921
    • Klingenberg, C.P.1    Leamy, L.J.2    Cheverud, J.M.3
  • 86
    • 27644549928 scopus 로고    scopus 로고
    • Integrating genotypic and expression data in a segregating mouse population to identify 5-lipoxygenase as a susceptibility gene for obesity and bone traits
    • MehrabianM, Allayee H, Stockton J, Lum PY, Drake TA, et al. Integrating genotypic and expression data in a segregating mouse population to identify 5-lipoxygenase as a susceptibility gene for obesity and bone traits. Nat Genet 2005, 37:1224-1233.
    • (2005) Nat Genet , vol.37 , pp. 1224-1233
    • Mehrabian, M.1    Allayee, H.2    Stockton, J.3    Lum, P.Y.4    Drake, T.A.5
  • 87
    • 0023492075 scopus 로고
    • Bone "mass" and the "mechanostat": a proposal
    • Frost HM. Bone "mass" and the "mechanostat": a proposal. Anat Rec 1987, 219:1-9.
    • (1987) Anat Rec , vol.219 , pp. 1-9
    • Frost, H.M.1
  • 88
    • 0021215715 scopus 로고
    • Dynamic strain similarity in vertebrates; an alternative to allometric limb bone scaling
    • Rubin CT, Lanyon LE. Dynamic strain similarity in vertebrates; an alternative to allometric limb bone scaling. J Theor Biol 1984, 107:321-327.
    • (1984) J Theor Biol , vol.107 , pp. 321-327
    • Rubin, C.T.1    Lanyon, L.E.2
  • 89
    • 0031770558 scopus 로고    scopus 로고
    • Mechanotransduction and functional response of the skeleton to physical stress: the mechanisms and mechanics of bone adaptation
    • Turner CH, Pavalko FM. Mechanotransduction and functional response of the skeleton to physical stress: the mechanisms and mechanics of bone adaptation. J Orthop Sci 1998, 3:346-355.
    • (1998) J Orthop Sci , vol.3 , pp. 346-355
    • Turner, C.H.1    Pavalko, F.M.2
  • 90
    • 5344246622 scopus 로고    scopus 로고
    • Sexual dimorphism of the femoral neck during the adolescent growth spurt: a structural analysis
    • Forwood MR, Bailey DA, Beck TJ, Mirwald RL, Baxter-Jones AD, et al. Sexual dimorphism of the femoral neck during the adolescent growth spurt: a structural analysis. Bone 2004, 35:973-981.
    • (2004) Bone , vol.35 , pp. 973-981
    • Forwood, M.R.1    Bailey, D.A.2    Beck, T.J.3    Mirwald, R.L.4    Baxter-Jones, A.D.5
  • 92
    • 0029855957 scopus 로고    scopus 로고
    • Body mass is the primary determinant of midfemoral bone acquisition during adolescent growth
    • Moro M, van der Meulen MC, Kiratli BJ, Marcus R, Bachrach LK, et al. Body mass is the primary determinant of midfemoral bone acquisition during adolescent growth. Bone 1996, 19:519-526.
    • (1996) Bone , vol.19 , pp. 519-526
    • Moro, M.1    van der Meulen, M.C.2    Kiratli, B.J.3    Marcus, R.4    Bachrach, L.K.5
  • 93
    • 33645235979 scopus 로고    scopus 로고
    • Who's afraid of the big bad Wolff? "Wolff's law" and bone functional adaptation
    • Ruff C, Holt B, Trinkaus E. Who's afraid of the big bad Wolff? "Wolff's law" and bone functional adaptation. Am J Phys Anthropol 2006, 129:484-498.
    • (2006) Am J Phys Anthropol , vol.129 , pp. 484-498
    • Ruff, C.1    Holt, B.2    Trinkaus, E.3
  • 94
    • 0030220576 scopus 로고    scopus 로고
    • Adaptation to differential loading: comparison of growth-related changes in cross-sectional properties of the human femur and humerus
    • Sumner DR, Andriacchi TP. Adaptation to differential loading: comparison of growth-related changes in cross-sectional properties of the human femur and humerus. Bone 1996, 19:121-126.
    • (1996) Bone , vol.19 , pp. 121-126
    • Sumner, D.R.1    Andriacchi, T.P.2
  • 96
    • 0034071062 scopus 로고    scopus 로고
    • Body size, body shape, and long bone strength in modern humans
    • Ruff CB. Body size, body shape, and long bone strength in modern humans. J Hum Evol 2000, 38:269-290.
    • (2000) J Hum Evol , vol.38 , pp. 269-290
    • Ruff, C.B.1
  • 97
    • 0034903537 scopus 로고    scopus 로고
    • Linking structural variability in long bone diaphyses to habitual behaviors: foragers from the southern African Later Stone Age and the Andaman Islands
    • Stock J, Pfeiffer S. Linking structural variability in long bone diaphyses to habitual behaviors: foragers from the southern African Later Stone Age and the Andaman Islands. Am J Phys Anthropol 2001, 115:337-348.
    • (2001) Am J Phys Anthropol , vol.115 , pp. 337-348
    • Stock, J.1    Pfeiffer, S.2
  • 98
    • 0033809726 scopus 로고    scopus 로고
    • Heterogeneity in the growth of the axial and appendicular skeleton in boys: implications for the pathogenesis of bone fragility in men
    • Bradney M, Karlsson MK, Duan Y, Stuckey S, Bass S, et al. Heterogeneity in the growth of the axial and appendicular skeleton in boys: implications for the pathogenesis of bone fragility in men. J Bone Miner Res 2000, 15:1871-1878.
    • (2000) J Bone Miner Res , vol.15 , pp. 1871-1878
    • Bradney, M.1    Karlsson, M.K.2    Duan, Y.3    Stuckey, S.4    Bass, S.5
  • 99
    • 0041331736 scopus 로고    scopus 로고
    • Growth in bone strength, body size, and muscle size in a juvenile longitudinal sample
    • Ruff C. Growth in bone strength, body size, and muscle size in a juvenile longitudinal sample. Bone 2003, 33:317-329.
    • (2003) Bone , vol.33 , pp. 317-329
    • Ruff, C.1
  • 100
    • 0030918078 scopus 로고    scopus 로고
    • Differential effect of gender on the sizes of the bones in the axial and appendicular skeletons
    • Gilsanz V, Kovanlikaya A, Costin G, Roe TF, Sayre J, et al. Differential effect of gender on the sizes of the bones in the axial and appendicular skeletons. J Clin Endocrinol Metab 1997, 82:1603-1607.
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 1603-1607
    • Gilsanz, V.1    Kovanlikaya, A.2    Costin, G.3    Roe, T.F.4    Sayre, J.5
  • 101
    • 0034977508 scopus 로고    scopus 로고
    • Does body size account for gender differences in femur bone density and geometry?
    • Looker AC, Beck TJ, Orwoll ES. Does body size account for gender differences in femur bone density and geometry? J Bone Miner Res 2001, 16:1291-1299.
    • (2001) J Bone Miner Res , vol.16 , pp. 1291-1299
    • Looker, A.C.1    Beck, T.J.2    Orwoll, E.S.3
  • 102
    • 34548430612 scopus 로고    scopus 로고
    • Genetic randomization reveals functional relationships among morphologic and tissuequality traits that contribute to bone strength and fragility
    • Jepsen KJ, Hu B, Tommasini SM, Courtland H-W, Price C, et al. Genetic randomization reveals functional relationships among morphologic and tissuequality traits that contribute to bone strength and fragility. Mamm Genome 2007, 18:492-507.
    • (2007) Mamm Genome , vol.18 , pp. 492-507
    • Jepsen, K.J.1    Hu, B.2    Tommasini, S.M.3    Courtland, H.-W.4    Price, C.5
  • 103
    • 34548585426 scopus 로고    scopus 로고
    • Construction of the femoral neck during growth determines its strength in old age
    • Zebaze RM, Jones A, Knackstedt M, Maalouf G, Seeman E. Construction of the femoral neck during growth determines its strength in old age. J Bone Miner Res 2007, 22:1055-1061.
    • (2007) J Bone Miner Res , vol.22 , pp. 1055-1061
    • Zebaze, R.M.1    Jones, A.2    Knackstedt, M.3    Maalouf, G.4    Seeman, E.5
  • 104
    • 0029924054 scopus 로고    scopus 로고
    • Dual-energy X-ray absorptiometry derived structural geometry for stress fracture prediction in male U.S. Marine Corps recruits
    • Beck TJ, Ruff CB, Mourtada FA, Shaffer RA, Maxwell-Williams K, et al. Dual-energy X-ray absorptiometry derived structural geometry for stress fracture prediction in male U.S. Marine Corps recruits. J Bone Miner Res 1996, 11:645-653.
    • (1996) J Bone Miner Res , vol.11 , pp. 645-653
    • Beck, T.J.1    Ruff, C.B.2    Mourtada, F.A.3    Shaffer, R.A.4    Maxwell-Williams, K.5
  • 105
    • 0033835154 scopus 로고    scopus 로고
    • Stress fracture in military recruits: gender differences in muscle and bone susceptibility factors
    • Beck TJ, Ruff CB, Shaffer RA, Betsinger K, Trone DW, et al. Stress fracture in military recruits: gender differences in muscle and bone susceptibility factors. Bone 2000, 27:437-444.
    • (2000) Bone , vol.27 , pp. 437-444
    • Beck, T.J.1    Ruff, C.B.2    Shaffer, R.A.3    Betsinger, K.4    Trone, D.W.5
  • 106
    • 0032873006 scopus 로고    scopus 로고
    • Ground reaction forces, bone characteristics, and tibial stress fracture in male runners
    • Crossley K, Bennell KL, Wrigley T, Oakes BW. Ground reaction forces, bone characteristics, and tibial stress fracture in male runners. Med Sci Sports Exerc 1999, 31:1088-1093.
    • (1999) Med Sci Sports Exerc , vol.31 , pp. 1088-1093
    • Crossley, K.1    Bennell, K.L.2    Wrigley, T.3    Oakes, B.W.4
  • 107
    • 0032848694 scopus 로고    scopus 로고
    • Vertebral bone mass, size, and volumetric density in women with spinal fractures
    • Duan Y, Parfitt A, Seeman E. Vertebral bone mass, size, and volumetric density in women with spinal fractures. J Bone Miner Res 1999, 14:1796-1802.
    • (1999) J Bone Miner Res , vol.14 , pp. 1796-1802
    • Duan, Y.1    Parfitt, A.2    Seeman, E.3
  • 109
    • 0028946274 scopus 로고
    • Vertebral size in elderly women with osteoporosis. Mechanical implications and relationship to fractures
    • Gilsanz V, Loro ML, Roe TF, Sayre J, Gilsanz R, et al. Vertebral size in elderly women with osteoporosis. Mechanical implications and relationship to fractures. J Clin Invest 1995, 95:2332-2337.
    • (1995) J Clin Invest , vol.95 , pp. 2332-2337
    • Gilsanz, V.1    Loro, M.L.2    Roe, T.F.3    Sayre, J.4    Gilsanz, R.5
  • 110
    • 33644985446 scopus 로고    scopus 로고
    • Low width of tubular bones is associated with increased risk of fragility fracture in elderly men-the MINOS study
    • Szulc P, Munoz F, Duboeuf F, Marchand F, Delmas PD. Low width of tubular bones is associated with increased risk of fragility fracture in elderly men-the MINOS study. Bone 2006, 38:595-602.
    • (2006) Bone , vol.38 , pp. 595-602
    • Szulc, P.1    Munoz, F.2    Duboeuf, F.3    Marchand, F.4    Delmas, P.D.5
  • 112
    • 0033795537 scopus 로고    scopus 로고
    • Structural and cellular changes during bone growth in healthy children
    • Parfitt AM, Travers R, Rauch F, Glorieux FH. Structural and cellular changes during bone growth in healthy children. Bone 2000, 27:487-494.
    • (2000) Bone , vol.27 , pp. 487-494
    • Parfitt, A.M.1    Travers, R.2    Rauch, F.3    Glorieux, F.H.4
  • 113
    • 0142241146 scopus 로고    scopus 로고
    • Structural and biomechanical basis of sexual dimorphism in femoral neck fragility has its origins in growth and aging
    • Duan Y, Beck TJ, Wang XF, Seeman E. Structural and biomechanical basis of sexual dimorphism in femoral neck fragility has its origins in growth and aging. J Bone Miner Res 2003, 18:1766-1774.
    • (2003) J Bone Miner Res , vol.18 , pp. 1766-1774
    • Duan, Y.1    Beck, T.J.2    Wang, X.F.3    Seeman, E.4
  • 114
    • 0035139604 scopus 로고    scopus 로고
    • Postnatal and pubertal skeletal changes contribute predominantly to the differences in peak bone density between C3H/HeJ and C57BL/6J mice
    • Richman C, Kutilek S, Miyakoshi N, Srivastava AK, Beamer WG, et al. Postnatal and pubertal skeletal changes contribute predominantly to the differences in peak bone density between C3H/HeJ and C57BL/6J mice. J Bone Miner Res 2001, 16:386-397.
    • (2001) J Bone Miner Res , vol.16 , pp. 386-397
    • Richman, C.1    Kutilek, S.2    Miyakoshi, N.3    Srivastava, A.K.4    Beamer, W.G.5
  • 115
    • 0034782841 scopus 로고    scopus 로고
    • Postmenopausal osteoporosis as a failure of bone's adaptation to functional loading: a hypothesis
    • Lanyon L, Skerry T. Postmenopausal osteoporosis as a failure of bone's adaptation to functional loading: a hypothesis. J Bone Miner Res 2001, 16:1937-1947.
    • (2001) J Bone Miner Res , vol.16 , pp. 1937-1947
    • Lanyon, L.1    Skerry, T.2
  • 116
    • 0037214288 scopus 로고    scopus 로고
    • The structural and hormonal basis of sex differences in peak appendicular bone strength in rats
    • Kim BT, Mosekilde L, Duan Y, Zhang XZ, Tornvig L, et al. The structural and hormonal basis of sex differences in peak appendicular bone strength in rats. J Bone Miner Res 2003, 18:150-155.
    • (2003) J Bone Miner Res , vol.18 , pp. 150-155
    • Kim, B.T.1    Mosekilde, L.2    Duan, Y.3    Zhang, X.Z.4    Tornvig, L.5
  • 117
    • 0026671788 scopus 로고
    • Mechanism of action of estrogen on intramembranous bone formation: regulation of osteoblast differentiation and activity
    • Turner RT, Backup P, Sherman PJ, Hill E, Evans GL, et al. Mechanism of action of estrogen on intramembranous bone formation: regulation of osteoblast differentiation and activity. Endocrinology 1992, 131:883-889.
    • (1992) Endocrinology , vol.131 , pp. 883-889
    • Turner, R.T.1    Backup, P.2    Sherman, P.J.3    Hill, E.4    Evans, G.L.5
  • 118
    • 0031788257 scopus 로고    scopus 로고
    • Moderate exercise during growth in prepubertal boys: changes in bone mass, size, volumetric density, and bone strength: a controlled prospective study
    • BradneyM, Pearce G, Naughton G, Sullivan C, Bass S, et al.Moderate exercise during growth in prepubertal boys: changes in bone mass, size, volumetric density, and bone strength: a controlled prospective study. J Bone Miner Res 1998, 13:1814-1821.
    • (1998) J Bone Miner Res , vol.13 , pp. 1814-1821
    • Bradney, M.1    Pearce, G.2    Naughton, G.3    Sullivan, C.4    Bass, S.5
  • 119
    • 0242456211 scopus 로고    scopus 로고
    • A comparison of bone geometry and cortical density at the mid-femur between prepuberty and young adulthood using magnetic resonance imaging
    • Hogler W, Blimkie CJ, Cowell CT, Kemp AF, Briody J, et al. A comparison of bone geometry and cortical density at the mid-femur between prepuberty and young adulthood using magnetic resonance imaging. Bone 2003, 33:771-778.
    • (2003) Bone , vol.33 , pp. 771-778
    • Hogler, W.1    Blimkie, C.J.2    Cowell, C.T.3    Kemp, A.F.4    Briody, J.5
  • 120
    • 0029360709 scopus 로고
    • Hindlimb suspension diminishes femoral crosssectional growth in the rat
    • van der Meulen MC, Morey-Holton ER, Carter DR. Hindlimb suspension diminishes femoral crosssectional growth in the rat. J Orthop Res 1995, 13:700-707.
    • (1995) J Orthop Res , vol.13 , pp. 700-707
    • van der Meulen, M.C.1    Morey-Holton, E.R.2    Carter, D.R.3
  • 122
    • 4444236062 scopus 로고    scopus 로고
    • Osteoblast-like cells from estrogen receptor alpha knockout mice have deficient responses to mechanical strain
    • Jessop HL, Suswillo RF, Rawlinson SC, Zaman G, Lee K, et al. Osteoblast-like cells from estrogen receptor alpha knockout mice have deficient responses to mechanical strain. J Bone Miner Res 2004, 19:938-946.
    • (2004) J Bone Miner Res , vol.19 , pp. 938-946
    • Jessop, H.L.1    Suswillo, R.F.2    Rawlinson, S.C.3    Zaman, G.4    Lee, K.5
  • 123
    • 0042265549 scopus 로고    scopus 로고
    • Endocrinology: bone adaptation requires oestrogen receptor-alpha
    • Lee K, Jessop H, Suswillo R, Zaman G, Lanyon L. Endocrinology: bone adaptation requires oestrogen receptor-alpha. Nature 2003, 424:389.
    • (2003) Nature , vol.424 , pp. 389
    • Lee, K.1    Jessop, H.2    Suswillo, R.3    Zaman, G.4    Lanyon, L.5
  • 124
    • 0030625938 scopus 로고    scopus 로고
    • Diaphyseal bone growth and adaptation: models and data
    • van der Meulen MC. Diaphyseal bone growth and adaptation: models and data. Stud Health Technol Inform 1997, 40:17-23.
    • (1997) Stud Health Technol Inform , vol.40 , pp. 17-23
    • van der Meulen, M.C.1
  • 126
    • 0032831348 scopus 로고    scopus 로고
    • Histomorphometric studies show that bone formation and bone mineral apposition rates are greater in C3H/HeJ (high-density) than C57BL/6J (low-density) mice during growth
    • Sheng MH, Baylink DJ, Beamer WG, Donahue LR, Rosen CJ, et al. Histomorphometric studies show that bone formation and bone mineral apposition rates are greater in C3H/HeJ (high-density) than C57BL/6J (low-density) mice during growth. Bone 1999, 25:421-429.
    • (1999) Bone , vol.25 , pp. 421-429
    • Sheng, M.H.1    Baylink, D.J.2    Beamer, W.G.3    Donahue, L.R.4    Rosen, C.J.5
  • 127
    • 0002864926 scopus 로고
    • On the nature of size factors
    • Wright S. On the nature of size factors. Genetics 1918, 3:367-374.
    • (1918) Genetics , vol.3 , pp. 367-374
    • Wright, S.1
  • 128
    • 0027026744 scopus 로고
    • Functional determinants of bone structure: beyond Wolff's law of bone transformation
    • Turner CH. Functional determinants of bone structure: beyond Wolff's law of bone transformation. Bone 1992, 13:403-409.
    • (1992) Bone , vol.13 , pp. 403-409
    • Turner, C.H.1
  • 129
    • 0036179760 scopus 로고    scopus 로고
    • Noninvasive loading of the murine tibia: an in vivo model for the study of mechanotransduction
    • Gross TS, Srinivasan S, Liu CC, Clemens TL, Bain SD. Noninvasive loading of the murine tibia: an in vivo model for the study of mechanotransduction. J Bone Miner Res 2002, 17:493-501.
    • (2002) J Bone Miner Res , vol.17 , pp. 493-501
    • Gross, T.S.1    Srinivasan, S.2    Liu, C.C.3    Clemens, T.L.4    Bain, S.D.5
  • 130
    • 0032452531 scopus 로고    scopus 로고
    • Association between insulin-like growth factor I and bone mineral density in older women and men: the Framingham Heart Study
    • Langlois JA, Rosen CJ, Visser M, Hannan MT, Harris T, et al. Association between insulin-like growth factor I and bone mineral density in older women and men: the Framingham Heart Study. J Clin Endocrinol Metab 1998, 83:4257-4262.
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 4257-4262
    • Langlois, J.A.1    Rosen, C.J.2    Visser, M.3    Hannan, M.T.4    Harris, T.5
  • 131
    • 0034635778 scopus 로고    scopus 로고
    • Low serum IGF-1 and occurrence of osteoporotic fractures in postmenopausal women
    • Garnero P, Sornay-Rendu E, Delmas PD. Low serum IGF-1 and occurrence of osteoporotic fractures in postmenopausal women. Lancet 2000, 355:898-899.
    • (2000) Lancet , vol.355 , pp. 898-899
    • Garnero, P.1    Sornay-Rendu, E.2    Delmas, P.D.3
  • 132
    • 0033805176 scopus 로고    scopus 로고
    • Mapping quantitative trait loci for serum insulin-like growth factor-1 levels inmice
    • Rosen CJ, Churchill GA, Donahue LR, Shultz KL, Burgess JK, et al. Mapping quantitative trait loci for serum insulin-like growth factor-1 levels inmice. Bone 2000, 27:521-528.
    • (2000) Bone , vol.27 , pp. 521-528
    • Rosen, C.J.1    Churchill, G.A.2    Donahue, L.R.3    Shultz, K.L.4    Burgess, J.K.5
  • 134
    • 0025220361 scopus 로고
    • The presence of classical insulin-like growth factor (IGF) type-I and -II receptors on mouse osteoblasts: autocrine/paracrine growth effect of IGFs?
    • Slootweg MC, Hoogerbrugge CM, de Poorter TL, Duursma SA, van Buul-Offers SC. The presence of classical insulin-like growth factor (IGF) type-I and -II receptors on mouse osteoblasts: autocrine/paracrine growth effect of IGFs? J Endocrinol 1990, 125:271-277.
    • (1990) J Endocrinol , vol.125 , pp. 271-277
    • Slootweg, M.C.1    Hoogerbrugge, C.M.2    de Poorter, T.L.3    Duursma, S.A.4    van Buul-Offers, S.C.5
  • 135
    • 0026787044 scopus 로고
    • Insulin-like growth factor-I supports formation and activation of osteoclasts
    • Mochizuki H, Hakeda Y, Wakatsuki N, Usui N, Akashi S, et al. Insulin-like growth factor-I supports formation and activation of osteoclasts. Endocrinology 1992, 131:1075-1080.
    • (1992) Endocrinology , vol.131 , pp. 1075-1080
    • Mochizuki, H.1    Hakeda, Y.2    Wakatsuki, N.3    Usui, N.4    Akashi, S.5
  • 137
    • 18544384875 scopus 로고    scopus 로고
    • IGF-I regulates osteoprotegerin (OPG) and receptor activator of nuclear factor-kappaB ligand in vitro and OPG in vivo
    • Rubin J, Ackert-Bicknell CL, Zhu L, Fan X, Murphy TC, et al. IGF-I regulates osteoprotegerin (OPG) and receptor activator of nuclear factor-kappaB ligand in vitro and OPG in vivo. J Clin Endocrinol Metab 2002, 87:4273-4279.
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 4273-4279
    • Rubin, J.1    Ackert-Bicknell, C.L.2    Zhu, L.3    Fan, X.4    Murphy, T.C.5
  • 138
    • 0033346805 scopus 로고    scopus 로고
    • Serum levels of insulin-like growth factor I and the density, volume, and cross-sectional area of cortical bone in children
    • Mora S, Pitukcheewanont P, Nelson JC, Gilsanz V. Serum levels of insulin-like growth factor I and the density, volume, and cross-sectional area of cortical bone in children. J Clin Endocrinol Metab 1999, 84:2780-2783.
    • (1999) J Clin Endocrinol Metab , vol.84 , pp. 2780-2783
    • Mora, S.1    Pitukcheewanont, P.2    Nelson, J.C.3    Gilsanz, V.4
  • 139
    • 34447326675 scopus 로고    scopus 로고
    • Genes in context: probing the genetics of fracture resistance
    • Sharkey NA, Lang DH. Genes in context: probing the genetics of fracture resistance. Exerc Sport Sci Rev 2007, 35:86-96.
    • (2007) Exerc Sport Sci Rev , vol.35 , pp. 86-96
    • Sharkey, N.A.1    Lang, D.H.2
  • 141
    • 0034864131 scopus 로고    scopus 로고
    • The developing bone: slave or master of its cells and molecules?
    • Rauch F, Schoenau E. The developing bone: slave or master of its cells and molecules? Pediatr Res 2001, 50:309-314.
    • (2001) Pediatr Res , vol.50 , pp. 309-314
    • Rauch, F.1    Schoenau, E.2
  • 142
    • 38549178032 scopus 로고    scopus 로고
    • Biological co-adaptation of morphological and composition traits contributes to mechanical functionality and skeletal fragility
    • Tommasini SM, Nasser P, Hu B, Jepsen KJ. Biological co-adaptation of morphological and composition traits contributes to mechanical functionality and skeletal fragility. J Bone Miner Res 2008, 23:236-246.
    • (2008) J Bone Miner Res , vol.23 , pp. 236-246
    • Tommasini, S.M.1    Nasser, P.2    Hu, B.3    Jepsen, K.J.4
  • 143
    • 0034896953 scopus 로고    scopus 로고
    • Understanding bone strength: size isn't everything
    • van derMeulenMC, Jepsen KJ, Mikic B. Understanding bone strength: size isn't everything. Bone 2001, 29:101-104.
    • (2001) Bone , vol.29 , pp. 101-104
    • van derMeulen, M.C.1    Jepsen, K.J.2    Mikic, B.3
  • 144
    • 34548488479 scopus 로고    scopus 로고
    • Bivariate linkage study of proximal hip geometry and body size indices: the Framingham study
    • Karasik D, Dupuis J, Cupples LA, Beck TJ, Mahaney MC, et al. Bivariate linkage study of proximal hip geometry and body size indices: the Framingham study. Calcif Tissue Int 2007, 81:162-173.
    • (2007) Calcif Tissue Int , vol.81 , pp. 162-173
    • Karasik, D.1    Dupuis, J.2    Cupples, L.A.3    Beck, T.J.4    Mahaney, M.C.5
  • 145
    • 17744375161 scopus 로고    scopus 로고
    • Genome screen for quantitative trait loci underlying normal variation in femoral structure
    • Koller DL, Liu G, Econs MJ, Hui SL, Morin PA, et al. Genome screen for quantitative trait loci underlying normal variation in femoral structure. J Bone Miner Res 2001, 16:985-991.
    • (2001) J Bone Miner Res , vol.16 , pp. 985-991
    • Koller, D.L.1    Liu, G.2    Econs, M.J.3    Hui, S.L.4    Morin, P.A.5
  • 146
    • 0035014333 scopus 로고    scopus 로고
    • The contribution of reduced peak accrual of bone and age-related bone loss to osteoporosis at the spine and hip: insights from the daughters of women with vertebral or hip fractures
    • Tabensky A, Duan Y, Edmonds J, Seeman E. The contribution of reduced peak accrual of bone and age-related bone loss to osteoporosis at the spine and hip: insights from the daughters of women with vertebral or hip fractures. J Bone Miner Res 2001, 16:1101-1107.
    • (2001) J Bone Miner Res , vol.16 , pp. 1101-1107
    • Tabensky, A.1    Duan, Y.2    Edmonds, J.3    Seeman, E.4
  • 147
    • 84942948140 scopus 로고
    • Postmenopausal osteoporosis: its clinical features
    • Albright F, Smith PH, Richardson AM. Postmenopausal osteoporosis: its clinical features. JAMA 1941, 116:2465-2474.
    • (1941) JAMA , vol.116 , pp. 2465-2474
    • Albright, F.1    Smith, P.H.2    Richardson, A.M.3
  • 148
    • 0021272903 scopus 로고
    • Bone mineral status in childhood accidental fractures
    • Chan GM, Hess M, Hollis J, Book LS. Bone mineral status in childhood accidental fractures. Am J Dis Child 1984, 138:569-570.
    • (1984) Am J Dis Child , vol.138 , pp. 569-570
    • Chan, G.M.1    Hess, M.2    Hollis, J.3    Book, L.S.4
  • 149
    • 0035192279 scopus 로고    scopus 로고
    • The biomechanical basis of vertebral body fragility in men and women
    • Duan Y, Seeman E, Turner CH. The biomechanical basis of vertebral body fragility in men and women. J Bone Miner Res 2001, 16:2276-2283.
    • (2001) J Bone Miner Res , vol.16 , pp. 2276-2283
    • Duan, Y.1    Seeman, E.2    Turner, C.H.3
  • 150
    • 0035200417 scopus 로고    scopus 로고
    • Can metacarpal cortical area predict the occurrence of hip fracture in women and men over 3 decades of follow-up? Results from the Framingham Osteoporosis Study
    • Kiel DP, Hannan MT, Broe KE, Felson DT, Cupples LA. Can metacarpal cortical area predict the occurrence of hip fracture in women and men over 3 decades of follow-up? Results from the Framingham Osteoporosis Study. J Bone Miner Res 2001, 16:2260-2266.
    • (2001) J Bone Miner Res , vol.16 , pp. 2260-2266
    • Kiel, D.P.1    Hannan, M.T.2    Broe, K.E.3    Felson, D.T.4    Cupples, L.A.5
  • 151
    • 0020616202 scopus 로고
    • Bone mineral content in children with fractures
    • Landin L, Nilsson BE. Bone mineral content in children with fractures. Clin Orthop Relat Res 1983, 178:292-296.
    • (1983) Clin Orthop Relat Res , vol.178 , pp. 292-296
    • Landin, L.1    Nilsson, B.E.2
  • 152
    • 0024892136 scopus 로고
    • The area moment of inertia of the tibia: a risk factor for stress fractures
    • Milgrom C, Giladi M, Simkin A, Rand N, Kedem R, et al. The area moment of inertia of the tibia: a risk factor for stress fractures. J Biomech 1989, 22:1243-1248.
    • (1989) J Biomech , vol.22 , pp. 1243-1248
    • Milgrom, C.1    Giladi, M.2    Simkin, A.3    Rand, N.4    Kedem, R.5
  • 153
    • 0031942290 scopus 로고    scopus 로고
    • Bone mineral density and bone size in men with primary osteoporosis and vertebral fractures
    • Vega E, Ghiringhelli G, Mautalen C, Rey Valzacchi G, Scaglia H, et al. Bone mineral density and bone size in men with primary osteoporosis and vertebral fractures. Calcif Tissue Int 1998, 62:465-469.
    • (1998) Calcif Tissue Int , vol.62 , pp. 465-469
    • Vega, E.1    Ghiringhelli, G.2    Mautalen, C.3    Rey Valzacchi, G.4    Scaglia, H.5
  • 154
    • 0141742300 scopus 로고    scopus 로고
    • Pleiotropy, homeostasis, and functional networks based on assays of cardiovascular traits in genetically randomized populations
    • Nadeau JH, Burrage LC, Restivo J, Pao YH, Churchill G, et al. Pleiotropy, homeostasis, and functional networks based on assays of cardiovascular traits in genetically randomized populations. Genome Res 2003, 13:2082-2091.
    • (2003) Genome Res , vol.13 , pp. 2082-2091
    • Nadeau, J.H.1    Burrage, L.C.2    Restivo, J.3    Pao, Y.H.4    Churchill, G.5


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