Bone response to in vivo mechanical loading in two breeds of mice

Calcified Tissue International

Volumn 63, Issue 5, 1998, Pages 442-449

  Akhter, M P ^a   Cullen, D M ^a   Pedersen, E A ^a   Kimmel, D B ^a   Recker, R R ^a  

^a CREIGHTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

External loading; Four point bending; In vivo strain; Tibia

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE DENSITY; CONTROLLED STUDY; FEMALE; IN VIVO STUDY; LOADING TEST; MECHANICAL STRESS; MOUSE; MOUSE STRAIN; NONHUMAN; PERIOSTEUM; PRIORITY JOURNAL; TIBIA; YOUNG MODULUS;

ANALYSIS OF VARIANCE; ANIMALS; BONE DENSITY; BONE MARROW; FIBULA; HINDLIMB; MICE; MICE, INBRED C3H; MICE, INBRED C57BL; RATS; SPECIES SPECIFICITY; TIBIA; WEIGHT-BEARING;

EID: 0031688655     PISSN: 0171967X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002239900554     Document Type: Article

References (61)

1. Libanati CR, Schulz EE, Shook JE, Bock M, Baylink DJ (1992) Hip mineral density in females with a recent hip fracture. J Clin Endocrinol Metab 74:351-356
2. Kroger H, Huopio J, Honkanen R, Tuppurainen M, Puntila E, Alhava E, Saarikoski S (1995) Prediction of fracture risk using axial bone mineral density in a perimenopausal population: a prospective study. J Bone Miner Res 10:302-306
3. Hui SL, Slemenda CW, Johnston CC Jr (1989) Baseline measurement of bone mass predicts fracture in white women. Ann Int Med 111:355-361
4. Gärdsell P, Johnell O, Nilsson BE (1989) Predicting fractures in women by using forearm bone densitometry. Calcif Tissue Int 45:235-242
5. Ross PD, Wasnich RD, Vogel JM (1988) Detection of prefracture spinal osteoporosis using bone mineral absorptiometry. J Bone Miner Res 3:1-11
6. Gärdsell P, Johnsell O, Nilsson BE (1991) The predictive value of bone loss for fragility fractures in women: a longitudinal study over fifteen years. Calcif Tissue Int 49:90-94
7. Black DM, Cummings SR, Genant HK, Nevitt MC, Palermo L, Browner W (1992) Axial and appendicular bone density predict fractures in older women. J Bone Miner Res 7:633-638
8. Slemenda CW, Christian JC, Reed T, Reister TK, Williams CJ, Johnston CC Jr (1992) Long-term bone loss in men: effects of genetic and environmental factors. Ann Intern Med 117:286-291
9. Slemenda CW, Christian JC, Williams CJ, Norton JA, Johnston CC (1991) Genetic determinants of bone mass in adult women: a reevaluation of the twin model and the potential importance of gene interaction on heritability estimates. J Bone Miner Res 6:561-567
10. Kelly PJ, Twomey L, Sambrook PN, Eisman JA (1990) Sex differences in peak adult bone mineral density. J Bone Miner Res 5:1169-1175
11. Matkovic V, Fontana D, Tominac C, Goel P, Chesnut CH III (1990) Factors that influence peak bone mass formation: a study of calcium balance and the inheritance of bone mass in adolescent females. Am J Clin Nutr 52:878-888
12. Liel Y, Edwards J, Shary J, Spicer KM, Gordon L, Bell NH (1988) The effects of race and body habitus on bone mineral density of the radius, hip, and spine in premenopausal women. J Clin Endocrinol Metab 66:1247-1250
13. McCormick DP, Ponder SW, Fawcett HD, Palmer JL (1991) Spinal bone mineral density in 335 normal and obese children and adolescents: evidence for ethnic and sex differences. J Bone Miner Res 6:507-525
14. Clark PJ (1955) The heritability of certain anthropometric characteristics as ascertained from measurements of twins. Am J Hum Genet 8:49-54
15. Dequeker J, Nijs J, Verstraeten A, Geusens P, Gevers G (1987) Genetic determinants of bone mineral content at the spine and radius: a twin study. Bone 8:207-209
16. Smith DM, Nance WE, Ke WK, Christian JC, Johnston CC (1973) Genetic factors in determining bone mass. J Clin Invest 52:2800-2808
17. Pocock NA, Eisman JA. Hopper JL, Yeates MG, Sambrook PN, Ebert S (1991) Genetic determinants of bone mass in adults: a twin study. J Clin Invest 80:706-710
18. Seeman E, Hopper JL, Bach LA, Cooper ME, Parkinson E, McKay J, Jerums G (1989) Reduced bone mass in daughters of women with osteoporosis. N Engl J Med 320:554-558
19. Evans RA, Marel GM, Lancaster EK, Kos S, Evans M, Wong SYP (1988) Bone mass is low in relatives of osteoporotic patients. Ann Intern Med 109:870-873
20. Tylavsky FA, Bortz AD, Hancock RL, Anderson JJB (1989) Familial resemblance of radial bone mass between premenopausal mothers and their college-age daughters. Calcif Tissue Int 45:265-272
21. Cooper GS, Umbach DM (1996) Are vitamin D receptor polymorphisms associated with bone mineral density? A metaanalysis. J Bone Miner Res 11:1850-1855
22. Dalsky GP, Stocke KS, Ehsani AA, Slatopolsky E, Lee WC, Birge SJ (1988) Weight-bearing exercise training and lumbar bone mineral content in postmenopausal women. Ann Intern Med 108:824-828
23. Snow-Harter C, Bouxsein ML, Lewis BT, Carter DR, Marcus R (1992) Effects of resistance and endurance exercise on bone mineral status of young women: a randomized exercise intervention trial. J Bone Miner Res 7:761-769
24. Goodship AE, Lanyon LE, McFie H (1979) Functional adaptation of bone to increased stress. J Bone Jt Surg 61B:539-546
25. Burr DB, Schaffler MB, Yang KH, Wu DD, Lukoschek M, Kandzari D, Sivaneri N, Blaha JD, Radin EL (1989) Skeletal change in response to altered strain environments: Is woven bone a response to elevated strain? Bone 10:215-221
26. Lanyon LE, Goodship AE, Pye CJ, MacFie JH (1982) Mechanically adaptive bone remodelling. J Biomech 15:141-154
27. Rubin CT, Lanyon LE (1984) Regulation of bone formation by applied dynamic loads. J Bone Jt Surg 66A:397-402
28. Rubin CT, Lanyon LE (1985) Regulation of bone mass by mechanical strain magnitude. Calcif Tissue Int 37:411-417
29. O'Connor JA, Lanyon LE, MacFie H (1982) The influence of strain rate on adaptive bone remodelling. J Biomech 15:767-781
30. Churches AE, Howlett CR (1982) Functional adaptation of bone in response to sinusoidally varying controlled compressive loading of the ovine metacarpus. Clin Orthop Rel Res 168:265-280
31. Chambers TJ, Evans M, Gardner TN, Turner-Smith A, Chow JWM (1993) Induction of bone formation in rat tail vertebrae by mechanical loading. Bone Miner 20:167-178
32. Seireg A, Kempke W (1969) Behavior of in vivo bone under cyclic loading. ASME Pub BHF-8:2-7
33. Turner CH, Akhter MP, Raab DM, Kimmel DB, Recker RR (1991) A non-invasive, in vivo model for studying strain adaptive bone modeling. Bone 12:73-79
34. Raab-Cullen DM, Akhter MP, Kimmel DB, Recker RR (1994) Bone response to alternate day mechanical loading of the rat tibia. J Bone Miner Res 9:203-212
35. Raab-Cullen DM, Akhter MP, Kimmel DB, Recker RR (1994) Periosteal bone formation is stimulated by externally induced bending strains. J Bone Miner Res 9:1143-1152
36. Akhter MP,. Raab DM, Turner CH, Kimmel DB, Recker RR (1992) Characterization of in vivo strain application during external loadine. J Biomech 12:1241-1246
37. Turner CH, Forwood MR, Rho JY, Yoshikawa T (1994) Mechanical loading thresholds for lamellar and woven bone formation. J Bone Miner Res 9:87-97
38. Torrance AG, Mosley JR, Suswillo RF, Lanyon LE (1994) Noninvasive loading of the rat ulna in vivo induces a strain-related modeling response uncomplicated by trauma or periosteal pressure. Calcif Tissue Int 54:241-247
39. Beamer WG, Donahue LR, Rosen CJ, Baylink DJ (1996) Genetic variability in adult bone density among inbred strains of mice. J Bone Miner Res 18:397-403
40. Dimai H, Linkhart T, Linkhart S, Beamer W, Donahue L, Rosen C, Farley J, Baylink D (1997) Bone formation may contribute to peak bone density differences between two inbred strains of mice. Am Soc Bone Miner Res 19th annual meeting (abstract F597), Cincinnati, OH
41. Rosen CJ, Dimai HP, Vereault D, Donahue LR, Beamer WG, Farley J, Linkhart T, Linkhart S, Mohan S, Baylink DJ (1997) Circulating and skeletal insulin-like growth factor-I (IGF-I) concentrations in two inbred strains of mice with different bone mineral densities. Bone 21(3)217-223
42. Chen C, Noland KA, Kalu DN (1997) Strain differences in bone density, calcium absorption and intestinal calcium transport between C3H/HeJ and C57BL/6J mice. Am Soc Bone Miner Res 19th annual meeting (abstract F594), Cincinnati, OH
43. Chen C, Kalu DN (1997) Strain differences in bone calcium absorption, serum 1,25 (OH)-2D and serum parathyroid hormone in response to dietry calcium restriction in C3H/HeJ and C57BL/6J mice. Am Soc Bone Miner Res 19th annual meeting (abstract 68). Cincinnati, OH
44. Kodama Y, Sheng M, Dimai H, Farley J, Wegedal J, Malpe R, Kutilek S, Beamer W, Donahue L, Rosen C, Baylink D (1997) Genetic regulation of the effect of immobilization to cause endosteal bone loss. Am Soc Bone Miner Res 19th annual meeting (abstract F597), Cincinnati, OH
45. Sinha YN, Salocks CB, Vanlerlaan WP (1975) Prolactin and growth hormone levels in different inbred strains of mice: patterns in association with estrous cycle, time of day and perphenazine stimulation. Endocrinology 97:1112-1122
46. Baron R, Vignery A, Neff L, Silverglate A, Santa Maria A (1983) Processing of undecalcified bone specimens for bone histomorphometry. In: Recker RR (ed) Bone histomorphometry: techniques and interpretation, CRC, Boca Raton, Florida) pp 13-35
47. Gies AA, Carter DR (1982) Experimental determination of whole long bone sectional properties. J Biomech 22:297-304
48. Burstein AH, Reilly DT, Martens M (1976) Aging of bone tissue: mechanical properties. J Bone Joint Surg 58A:82-86
49. Cochran GVB (1972) Implantation of strain gages on bone in vivo. J Biomech 5:119-123
50. Keller TS, Spengler DM (1982) In vivo strain gage implantation in rats. J Biomech 15:911-917
51. Keller TS, Spengler DM (1989) Regulation of bone stress and strain in the immature and mature rat femur. J Biomech 22: 1115-1127
52. Altschuler RA, Dolan DF, Ptok M, Gholizadeh G, Bonadio J, Hawkins JE (1991) An evaluation of otopathology in the MOV-13 transgenic mutant mouse. Ann N Y Acad Sci 630: 249-252
53. Bonadio J, Saunders TL, Tsai E, Goldstein SA, Morris-Wiman J, Brinkley L, Dolan DF, Altschuler RA, Hawkins JE Jr, Bateman JF, (1990) Transgenic mouse model of the mild dominant form of osteogenesis imperfecta. Proc Natl Acad Sci USA 87:7145-7147
54. Cassella JP, Pereira R, Khillan JS, Prockop DJ, Garrington N, Ali SY (1994) An ultrastructural, microanalytical, and spectroscopic study of bone from a transgenic mouse with a COLA1.A1 pro-Alpha-1 mutation. Bone 15:611-619
55. Shuldiner AR (1996) Transgenic animals. N Engl J Med 334: 653-655
56. Poli V, Balena R, Fattori E, Markatos A, Yamamoto M, Tanaka H, Ciliberto G, Rodan GA, Costantini F (1994) Interleukin-6-deficient mice are protected from bone loss caused by estrogen depletion. EMBO J 13:1189-1196
57. Mikic B, van der Meulen MC, Kingsley DM, Carter-DR (1995) Long bone geometry and strength in adult BMP-5-deficient mice. Bone 16:445-454
58. Koretsky AP (1992) Investigation of cell physiology in the animal using transgenic technology. Am J Physiol 262:C261-C275
59. Ducy P, Desbois C, Boyce B, Pinero G, Story B, Dunstan C, Smith E, Bonadio J, Goldstein S, Gundberg C, Bradley A, Karsenty G (1996) Increased bone formation in osteocalcin-deficient mice. Nature 382:448-452
60. Majzoub JA, Muglia LJ (1996) Molecular medicine: knockout mice. N Engl J Med 334:906-907
61. Marks SC, Lane PW (1976) Osteopetrosis, a new recessive skeletal mutation on chromosome 12 of the mouse. J Heredity 67:11-18