Synthesis and molecular docking studies of 1-phenyl-4-glycosyl-dihydropyridines as potent antileishmanial agents

European Journal of Medicinal Chemistry

Volumn 45, Issue 6, 2010, Pages 2381-2388

  Pandey, Vivek Parashar ^a   Bisht, Surendra Singh ^a   Mishra, Mridul ^a   Kumar, Ashutosh ^a   Siddiqi, Mohammad Imran ^a   Verma, Aditya ^a   Mittal, Monika ^a   Sane, Shraddha A ^a   Gupta, Suman ^a   Tripathi, Rama P ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

[No Author keywords available]

Indexed keywords

1 PHENYL 4 GLYCOSYL DIHYDROPYRIDINE DERIVATIVE; 2,6 DIMETHYL 4 (1',2' ORTHO ISOPROPYLIDENE 3' ORTHO METHYL BETA LEVO THREO PENTOFURANOS 4' YL) 1 (4 BROMOPHENYL) 1,4 DIHYDROPYRIDINE 3,5 DICARBOXYLIC ACID DIMETHYL ESTER; 2,6 DIMETHYL 4 (1',2' ORTHO ISOPROPYLIDENE 3' ORTHO METHYL BETA LEVO THREO PENTOFURANOS 4' YL) 1 (4 METHOXYPHENYL) 1,4 DIHYDROPYRIDINE 3,5 DICARBOXYLIC ACID DIMETHYL ESTER; 2,6 DIMETHYL 4 (1',2' ORTHO ISOPROPYLIDENE 3' ORTHO METHYL BETA LEVO THREO PENTOFURANOS 4' YL) 1 (4 METHYLPHENYL) 1,4 DIHYDROPYRIDINE 3,5 DICARBOXYLIC ACID DIMETHYL ESTER; 2,6 DIMETHYL 4 (1',2' ORTHO ISOPROPYLIDENE BETA LEVO THREO PENTOFURANOS 4' YL) 1 (4 CHLOROPHENYL) 1,4 DIHYDROPYRIDINE 3,5 DICARBOXYLIC ACID DIMETHYL ESTER; 2,6 DIMETHYL 4 (3' ORTHO BENZYL 1',2' ORTHO ISOPROPYLIDENE BETA LEVO THREO PENTOFURANOS 4' YL) 1 (4 METHOXYPHENYL) 1,4 DIHYDROPYRIDINE 3,5 DICARBOXYLIC ACID DIMETHYL ESTER; 3 HYDROXYACYL COENZYME A DEHYDROGENASE; ALDEHYDE; ANILINE; ANTILEISHMANIAL AGENT; DICARBOXYLIC ACID; DIHYDROPYRIDINE DERIVATIVE; MILTEFOSINE; PENTAMIDINE; TETRABUTYLAMMONIUM; UNCLASSIFIED DRUG;

AMASTIGOTE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIMICROBIAL ACTIVITY; ARTICLE; CATALYST; CHEMICAL REACTION; CONTROLLED STUDY; DRUG SCREENING; DRUG SELECTIVITY; DRUG SYNTHESIS; FEMALE; GLYCOSYLATION; IN VITRO STUDY; IN VIVO STUDY; LEISHMANIA DONOVANI; MALE; MOLECULAR DOCKING; MOUSE; NONHUMAN; ONE POT SYNTHESIS; PROMASTIGOTE; RAT; TARGET ORGANISM;

ANIMALS; ANTIPROTOZOAL AGENTS; CELL LINE; LEISHMANIA DONOVANI; LIFE CYCLE STAGES; MICE; MODELS, MOLECULAR; MOLECULAR CONFORMATION; OXIDOREDUCTASES; PYRIDINES;

EID: 77950931365     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2010.02.018     Document Type: Article

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