Glucose stimulates cholesterol 7 α-hydroxylase gene transcription in human hepatocytes

Journal of Lipid Research

Volumn 51, Issue 4, 2010, Pages 832-842

  Li, Tiangang ^a   Chanda, Dipanjan ^b   Zhang, Yanqiao ^a   SikChoi, Hueng ^b   Chiang, John Y L ^a  

^a NORTHEAST OHIO MEDICAL UNIVERSITY   (United States)

^b Chonnam National University   (South Korea)

Author keywords

AMPK; Bile acid synthesis; Cholestasis; CYP7A1; Epigenetic; Glucose; Nuclear receptors

Indexed keywords

ACETYL COENZYME A; ADENOSINE TRIPHOSPHATE CITRATE LYASE; BILE ACID; CHOLESTEROL 7ALPHA MONOOXYGENASE; GLUCOSE; HEPATOCYTE NUCLEAR FACTOR 4ALPHA; HISTONE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MESSENGER RNA; ADENOSINE TRIPHOSPHATE CITRATE SYNTHASE; DNA BINDING PROTEIN; HEPATOCYTE NUCLEAR FACTOR 4; HNF4A PROTEIN, HUMAN;

ACETYLATION; ARTICLE; BILE ACID SYNTHESIS; CHROMATIN; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INDUCTION; EPIGENETICS; GENETIC TRANSCRIPTION; GLUCOSE METABOLISM; HUMAN; HUMAN CELL; LIVER CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN METHYLATION; REGULATOR GENE; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; CELL CULTURE; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETIC EPIGENESIS; GENETICS; HEPG2 CELL LINE; HYPERGLYCEMIA; METABOLISM; METHYLATION; REPORTER GENE; RNA INTERFERENCE;

ACETYLATION; AMP-ACTIVATED PROTEIN KINASES; ATP CITRATE (PRO-S)-LYASE; BILE ACIDS AND SALTS; CELLS, CULTURED; CHOLESTEROL 7-ALPHA-HYDROXYLASE; DNA-BINDING PROTEINS; EPIGENESIS, GENETIC; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENES, REPORTER; GLUCOSE; HEP G2 CELLS; HEPATOCYTE NUCLEAR FACTOR 4; HEPATOCYTES; HISTONES; HUMANS; HYPERGLYCEMIA; METHYLATION; RNA INTERFERENCE; RNA, MESSENGER;

EID: 77950608917     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M002782     Document Type: Article

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