메뉴 건너뛰기




Volumn 10, Issue 5, 2010, Pages 547-555

Immunoactive effects of cannabinoids: Considerations for the therapeutic use of cannabinoid receptor agonists and antagonists

Author keywords

Cannabinoids; GPCR; Immunosuppression; Metabolic disorders; Neuroimmunology; Signaling

Indexed keywords

1 (2,4 DICHLOROPHENYL) 5 (4 IODOPHENYL) 4 METHYL N (1 PIPERIDYL) 1H PYRAZOLE 3 CARBOXAMIDE; 1 (2,4 DICHLOROPHENYL) 5 (4 IODOPHENYL) 4 METHYL N MORPHOLINO 1H PYRAZOLE 3 CARBOXAMIDE; 1 DEOXY 3 (1,1 DIMETHYLBUTYL) DELTA8 TETRAHYDROCANNABINOL; 2 ARACHIDONOYLGLYCEROL; 2 METHYL 3 (1 NAPHTHOYL) 1 PROPYLINDOLE; 2,3 DIHYDRO 5 METHYL 3 (MORPHOLINOMETHYL) 6 (1 NAPHTHOYL)PYRROLO[1,2,3 DE][1,4]BENZOXAZINE; 3 [2 HYDROXY 4 (1,1 DIMETHYLHEPTYL)PHENYL]CYCLOHEXANOL; 4 (1,1 DIMETHYLHEPTYL) 1',2',3',4',5',6' HEXAHYDRO 2,3' DIHYDROXY 6' (3 HYDROXYPROPYL)BIPHENYL; 4 [4 (1,1 DIMETHYLHEPTYL) 2,6 DIMETHOXYPHENYL] 6,6 DIMETHYLBICYCLO[3.1.1]HEPT 2 EN 2 YLMETHANOL; 4 [6 METHOXY 2 (4 METHOXYPHENYL) 3 BENZOFURANYLCARBONYL]BENZONITRILE; 5 (1,1 DIMETHYLHEPTYL) 2 (3 HYDROXY 7 HYDROXYMETHYLDECAHYDRO 1 NAPHTHYL)PHENOL; 5 (4 CHLORO 3 METHYLPHENYL) 1 (4 METHYLBENZYL) N (1,3,3 TRIMETHYLBICYCLO[2.2.1]HEPTAN 2 YL) 3 PYRAZOLECARBOXAMIDE; 6 IODO 3 (4 METHOXYBENZOYL) 2 METHYL 1 (2 MORPHOLINOETHYL)INDOLE; ANANDAMIDE; AR 171416A; CANNABIDIOL; CANNABINOID; CANNABINOID RECEPTOR AGONIST; CANNABINOID RECEPTOR ANTAGONIST; DEXANABINOL; DOCOSATETRAENOYLETHANOLAMIDE; DRONABINOL; HOMO GAMMA LINOLENOYLETHANOLAMIDE; JWH 139; L 759633; L 759656; METHANANDAMIDE; NOLADIN ETHER; O 1812; O 1821; RIMONABANT; UNCLASSIFIED DRUG; UNINDEXED DRUG;

EID: 77950504056     PISSN: 15675769     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.intimp.2010.02.012     Document Type: Review
Times cited : (42)

References (129)
  • 1
    • 0033847789 scopus 로고    scopus 로고
    • Looking back at Cannabis research
    • Mechoulam R. Looking back at Cannabis research. Curr Pharm Des 6 (2000) 1313-1322
    • (2000) Curr Pharm Des , vol.6 , pp. 1313-1322
    • Mechoulam, R.1
  • 2
    • 0033660254 scopus 로고    scopus 로고
    • A historical overview of chemical research on cannabinoids
    • Mechoulam R., and Hanus L. A historical overview of chemical research on cannabinoids. Chem Phys Lipids 108 (2000) 1-13
    • (2000) Chem Phys Lipids , vol.108 , pp. 1-13
    • Mechoulam, R.1    Hanus, L.2
  • 3
    • 0015221354 scopus 로고
    • The isolation and structure of delta-1-tetrahydrocannabinol and other neutral cannabinoids from hashish
    • Gaoni Y., and Mechoulam R. The isolation and structure of delta-1-tetrahydrocannabinol and other neutral cannabinoids from hashish. J Am Chem Soc 93 (1971) 217-224
    • (1971) J Am Chem Soc , vol.93 , pp. 217-224
    • Gaoni, Y.1    Mechoulam, R.2
  • 4
    • 0025078511 scopus 로고
    • Marijuana receptor gene cloned
    • Marx J. Marijuana receptor gene cloned. Science 249 (1990) 624-626
    • (1990) Science , vol.249 , pp. 624-626
    • Marx, J.1
  • 5
    • 0025325535 scopus 로고
    • Structure of a cannabinoid receptor and functional expression of the cloned cDNA
    • Matsuda L.A., Lolait S.J., Brownstein M.J., Young A.C., and Bonner T.I. Structure of a cannabinoid receptor and functional expression of the cloned cDNA. Nature 346 (1990) 561-564
    • (1990) Nature , vol.346 , pp. 561-564
    • Matsuda, L.A.1    Lolait, S.J.2    Brownstein, M.J.3    Young, A.C.4    Bonner, T.I.5
  • 6
    • 0027515373 scopus 로고
    • Molecular characterization of a peripheral receptor for cannabinoids
    • Munro S., Thomas K.L., and Abu-Shaar M. Molecular characterization of a peripheral receptor for cannabinoids. Nature 365 (1993) 61-65
    • (1993) Nature , vol.365 , pp. 61-65
    • Munro, S.1    Thomas, K.L.2    Abu-Shaar, M.3
  • 7
    • 0028987880 scopus 로고
    • Pharmacology of cannabinoid receptors
    • Howlett A.C. Pharmacology of cannabinoid receptors. Annu Rev Pharmacol Toxicol 35 (1995) 607-634
    • (1995) Annu Rev Pharmacol Toxicol , vol.35 , pp. 607-634
    • Howlett, A.C.1
  • 8
    • 18444376760 scopus 로고    scopus 로고
    • International Union of Pharmacology. XXVII. Classification of cannabinoid receptors
    • Howlett A.C., Barth F., Bonner T.I., Cabral G., Casellas P., Devane W.A., et al. International Union of Pharmacology. XXVII. Classification of cannabinoid receptors. Pharmacol Rev 54 (2002) 161-202
    • (2002) Pharmacol Rev , vol.54 , pp. 161-202
    • Howlett, A.C.1    Barth, F.2    Bonner, T.I.3    Cabral, G.4    Casellas, P.5    Devane, W.A.6
  • 9
    • 33645502759 scopus 로고    scopus 로고
    • The pharmacology of cannabinoid receptors and their ligands: an overview
    • Pertwee R.G. The pharmacology of cannabinoid receptors and their ligands: an overview. Int J Obes (Lond) 30 Suppl 1 (2006) S13-S18
    • (2006) Int J Obes (Lond) , vol.30 , Issue.SUPPL. 1
    • Pertwee, R.G.1
  • 10
    • 0029778985 scopus 로고    scopus 로고
    • Role of cyclic AMP in the actions of cannabinoid receptors
    • Childers S.R., and Deadwyler S.A. Role of cyclic AMP in the actions of cannabinoid receptors. Biochem Pharmacol 52 (1996) 819-827
    • (1996) Biochem Pharmacol , vol.52 , pp. 819-827
    • Childers, S.R.1    Deadwyler, S.A.2
  • 12
    • 63849237026 scopus 로고    scopus 로고
    • Cannabinoid receptors: a brief history and "what's hot"
    • Graham E.S., Ashton J.C., and Glass M. Cannabinoid receptors: a brief history and "what's hot". Front Biosci 14 (2009) 944-957
    • (2009) Front Biosci , vol.14 , pp. 944-957
    • Graham, E.S.1    Ashton, J.C.2    Glass, M.3
  • 14
    • 0032926695 scopus 로고    scopus 로고
    • The effects of cannabinoids on the brain
    • Ameri A. The effects of cannabinoids on the brain. Prog Neurobiol 58 (1999) 315-348
    • (1999) Prog Neurobiol , vol.58 , pp. 315-348
    • Ameri, A.1
  • 15
    • 0033538441 scopus 로고    scopus 로고
    • Cannabinoids, hippocampal function and memory
    • Hampson R.E., and Deadwyler S.A. Cannabinoids, hippocampal function and memory. Life Sci 65 (1999) 715-723
    • (1999) Life Sci , vol.65 , pp. 715-723
    • Hampson, R.E.1    Deadwyler, S.A.2
  • 16
    • 0033545866 scopus 로고    scopus 로고
    • Increased mortality, hypoactivity, and hypoalgesia in cannabinoid CB1 receptor knockout mice
    • Zimmer A., Zimmer A.M., Hohmann A.G., Herkenham M., and Bonner T.I. Increased mortality, hypoactivity, and hypoalgesia in cannabinoid CB1 receptor knockout mice. Proc Natl Acad Sci U S A 96 (1999) 5780-5785
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 5780-5785
    • Zimmer, A.1    Zimmer, A.M.2    Hohmann, A.G.3    Herkenham, M.4    Bonner, T.I.5
  • 17
    • 0032802188 scopus 로고    scopus 로고
    • Pharmacology of cannabinoid receptor ligands
    • Pertwee R.G. Pharmacology of cannabinoid receptor ligands. Curr Med Chem 6 (1999) 635-664
    • (1999) Curr Med Chem , vol.6 , pp. 635-664
    • Pertwee, R.G.1
  • 18
    • 9644302602 scopus 로고    scopus 로고
    • Differential effects of THC- or CBD-rich cannabis extracts on working memory in rats
    • Fadda P., Robinson L., Fratta W., Pertwee R.G., and Riedel G. Differential effects of THC- or CBD-rich cannabis extracts on working memory in rats. Neuropharmacology 47 (2004) 1170-1179
    • (2004) Neuropharmacology , vol.47 , pp. 1170-1179
    • Fadda, P.1    Robinson, L.2    Fratta, W.3    Pertwee, R.G.4    Riedel, G.5
  • 19
    • 0034766553 scopus 로고    scopus 로고
    • Pharmacological actions and therapeutic uses of cannabis and cannabinoids
    • Kumar R.N., Chambers W.A., and Pertwee R.G. Pharmacological actions and therapeutic uses of cannabis and cannabinoids. Anaesthesia 56 (2001) 1059-1068
    • (2001) Anaesthesia , vol.56 , pp. 1059-1068
    • Kumar, R.N.1    Chambers, W.A.2    Pertwee, R.G.3
  • 20
    • 53249093794 scopus 로고    scopus 로고
    • Endocannabinoids, metabolic regulation, and the role of diet
    • Carr T.P., Jesch E.D., and Brown A.W. Endocannabinoids, metabolic regulation, and the role of diet. Nutr Res 28 (2008) 641-650
    • (2008) Nutr Res , vol.28 , pp. 641-650
    • Carr, T.P.1    Jesch, E.D.2    Brown, A.W.3
  • 22
    • 33745506297 scopus 로고    scopus 로고
    • Endocannabinoids and the gastrointestinal tract
    • Massa F., and Monory K. Endocannabinoids and the gastrointestinal tract. J Endocrinol Investig 29 (2006) 47-57
    • (2006) J Endocrinol Investig , vol.29 , pp. 47-57
    • Massa, F.1    Monory, K.2
  • 23
    • 42349083886 scopus 로고    scopus 로고
    • Endocannabinoids, blood pressure and the human heart
    • Sarzani R. Endocannabinoids, blood pressure and the human heart. J Neuroendocrinol 20 Suppl 1 (2008) 58-62
    • (2008) J Neuroendocrinol , vol.20 , Issue.SUPPL. 1 , pp. 58-62
    • Sarzani, R.1
  • 24
    • 36549015066 scopus 로고    scopus 로고
    • The endocannabinoid system and gut-brain signalling
    • Storr M.A., and Sharkey K.A. The endocannabinoid system and gut-brain signalling. Curr Opin Pharmacol 7 (2007) 575-582
    • (2007) Curr Opin Pharmacol , vol.7 , pp. 575-582
    • Storr, M.A.1    Sharkey, K.A.2
  • 25
    • 0033661798 scopus 로고    scopus 로고
    • Cannabinoid receptors and the regulation of immune response
    • Berdyshev E.V. Cannabinoid receptors and the regulation of immune response. Chem Phys Lipids 108 (2000) 169-190
    • (2000) Chem Phys Lipids , vol.108 , pp. 169-190
    • Berdyshev, E.V.1
  • 28
    • 0037441460 scopus 로고    scopus 로고
    • Prospects for cannabinoids as anti-inflammatory agents
    • Zurier R.B. Prospects for cannabinoids as anti-inflammatory agents. J Cell Biochem 88 (2003) 462-466
    • (2003) J Cell Biochem , vol.88 , pp. 462-466
    • Zurier, R.B.1
  • 29
    • 0031732250 scopus 로고    scopus 로고
    • Anandamide synthesis is induced by arachidonate mobilizing agonists in cells of the immune system
    • Pestonjamasp V.K., and Burstein S.H. Anandamide synthesis is induced by arachidonate mobilizing agonists in cells of the immune system. Biochim Biophys Acta 1394 (1998) 249-260
    • (1998) Biochim Biophys Acta , vol.1394 , pp. 249-260
    • Pestonjamasp, V.K.1    Burstein, S.H.2
  • 30
    • 0031031557 scopus 로고    scopus 로고
    • Biosynthesis, uptake, and degradation of anandamide and palmitoylethanolamide in leukocytes
    • Bisogno T., Maurelli S., Melck D., De Petrocellis L., and Di Marzo V. Biosynthesis, uptake, and degradation of anandamide and palmitoylethanolamide in leukocytes. J Biol Chem 272 (1997) 3315-3323
    • (1997) J Biol Chem , vol.272 , pp. 3315-3323
    • Bisogno, T.1    Maurelli, S.2    Melck, D.3    De Petrocellis, L.4    Di Marzo, V.5
  • 31
    • 34250209535 scopus 로고    scopus 로고
    • Attenuation of allergic contact dermatitis through the endocannabinoid system
    • Karsak M., Gaffal E., Date R., Wang-Eckhardt L., Rehnelt J., Petrosino S., et al. Attenuation of allergic contact dermatitis through the endocannabinoid system. Science 316 (2007) 1494-1497
    • (2007) Science , vol.316 , pp. 1494-1497
    • Karsak, M.1    Gaffal, E.2    Date, R.3    Wang-Eckhardt, L.4    Rehnelt, J.5    Petrosino, S.6
  • 32
    • 28544450602 scopus 로고    scopus 로고
    • The endocannabinoid system in the physiology and pathophysiology of the gastrointestinal tract
    • Massa F., Storr M., and Lutz B. The endocannabinoid system in the physiology and pathophysiology of the gastrointestinal tract. J Mol Med 83 (2005) 944-954
    • (2005) J Mol Med , vol.83 , pp. 944-954
    • Massa, F.1    Storr, M.2    Lutz, B.3
  • 34
    • 0034660138 scopus 로고    scopus 로고
    • Delta 9-tetrahydrocannabinol treatment suppresses immunity and early IFN-gamma, IL-12, and IL-12 receptor beta 2 responses to Legionella pneumophila infection
    • Klein T.W., Newton C.A., Nakachi N., and Friedman H. Delta 9-tetrahydrocannabinol treatment suppresses immunity and early IFN-gamma, IL-12, and IL-12 receptor beta 2 responses to Legionella pneumophila infection. J Immunol 164 (2000) 6461-6466
    • (2000) J Immunol , vol.164 , pp. 6461-6466
    • Klein, T.W.1    Newton, C.A.2    Nakachi, N.3    Friedman, H.4
  • 35
    • 0028065110 scopus 로고
    • Secondary immunity to Legionella pneumophila and Th1 activity are suppressed by delta-9-tetrahydrocannabinol injection
    • Newton C.A., Klein T.W., and Friedman H. Secondary immunity to Legionella pneumophila and Th1 activity are suppressed by delta-9-tetrahydrocannabinol injection. Infect Immun 62 (1994) 4015-4020
    • (1994) Infect Immun , vol.62 , pp. 4015-4020
    • Newton, C.A.1    Klein, T.W.2    Friedman, H.3
  • 36
    • 0025914817 scopus 로고
    • Selective inhibition of natural killer but not natural cytotoxic activity in a cloned cell line by delta-9-tetrahydrocannabinol
    • Wang M., Richards A.L., Friedman H., and Djeu J.Y. Selective inhibition of natural killer but not natural cytotoxic activity in a cloned cell line by delta-9-tetrahydrocannabinol. J Leukoc Biol 50 (1991) 192-197
    • (1991) J Leukoc Biol , vol.50 , pp. 192-197
    • Wang, M.1    Richards, A.L.2    Friedman, H.3    Djeu, J.Y.4
  • 37
    • 0015988672 scopus 로고
    • Inhibition of cellular mediated immunity in marihuana smokers
    • Nahas G.G., Suciu-Foca N., Armand J.P., and Morishima A. Inhibition of cellular mediated immunity in marihuana smokers. Science 183 (1974) 419-420
    • (1974) Science , vol.183 , pp. 419-420
    • Nahas, G.G.1    Suciu-Foca, N.2    Armand, J.P.3    Morishima, A.4
  • 38
    • 0016677517 scopus 로고
    • Alterations in the cellular-mediated immune responsiveness of chronic marihuana smokers
    • Petersen B.H., Lemberger L., Graham J., and Dalton B. Alterations in the cellular-mediated immune responsiveness of chronic marihuana smokers. Psychopharmacol Commun 1 (1975) 67-74
    • (1975) Psychopharmacol Commun , vol.1 , pp. 67-74
    • Petersen, B.H.1    Lemberger, L.2    Graham, J.3    Dalton, B.4
  • 39
    • 0028225217 scopus 로고
    • Delta-9-tetrahydrocannabinol treatment results in a suppression of interleukin-2-induced cellular activities in human and murine lymphocytes
    • Trisler K., and Specter S. Delta-9-tetrahydrocannabinol treatment results in a suppression of interleukin-2-induced cellular activities in human and murine lymphocytes. Int J Immunopharmacol 16 (1994) 593-603
    • (1994) Int J Immunopharmacol , vol.16 , pp. 593-603
    • Trisler, K.1    Specter, S.2
  • 40
    • 8444244202 scopus 로고    scopus 로고
    • Effect of cannabinoid ingestion (in the form of bhang) on the immune system of high school and university students
    • El-Gohary M., and Eid M.A. Effect of cannabinoid ingestion (in the form of bhang) on the immune system of high school and university students. Hum Exp Toxicol 23 (2004) 149-156
    • (2004) Hum Exp Toxicol , vol.23 , pp. 149-156
    • El-Gohary, M.1    Eid, M.A.2
  • 41
    • 0035191240 scopus 로고    scopus 로고
    • Differential expression of the CB2 cannabinoid receptor by rodent macrophages and macrophage-like cells in relation to cell activation
    • Carlisle S.J., Marciano-Cabral F., Staab A., Ludwick C., and Cabral G.A. Differential expression of the CB2 cannabinoid receptor by rodent macrophages and macrophage-like cells in relation to cell activation. Int Immunopharmacol 2 (2002) 69-82
    • (2002) Int Immunopharmacol , vol.2 , pp. 69-82
    • Carlisle, S.J.1    Marciano-Cabral, F.2    Staab, A.3    Ludwick, C.4    Cabral, G.A.5
  • 42
    • 22044449933 scopus 로고    scopus 로고
    • Activation of cannabinoid CB2 receptor negatively regulates IL-12p40 production in murine macrophages: role of IL-10 and ERK1/2 kinase signaling
    • Correa F., Mestre L., Docagne F., and Guaza C. Activation of cannabinoid CB2 receptor negatively regulates IL-12p40 production in murine macrophages: role of IL-10 and ERK1/2 kinase signaling. Br J Pharmacol 145 (2005) 441-448
    • (2005) Br J Pharmacol , vol.145 , pp. 441-448
    • Correa, F.1    Mestre, L.2    Docagne, F.3    Guaza, C.4
  • 43
    • 27744493300 scopus 로고    scopus 로고
    • 2-Arachidonoylglycerol, an endogenous cannabinoid receptor ligand, enhances the adhesion of HL-60 cells differentiated into macrophage-like cells and human peripheral blood monocytes
    • Gokoh M., Kishimoto S., Oka S., Metani Y., and Sugiura T. 2-Arachidonoylglycerol, an endogenous cannabinoid receptor ligand, enhances the adhesion of HL-60 cells differentiated into macrophage-like cells and human peripheral blood monocytes. FEBS Lett 579 (2005) 6473-6478
    • (2005) FEBS Lett , vol.579 , pp. 6473-6478
    • Gokoh, M.1    Kishimoto, S.2    Oka, S.3    Metani, Y.4    Sugiura, T.5
  • 44
    • 26844448746 scopus 로고    scopus 로고
    • Modulation of the cannabinoid CB2 receptor in microglial cells in response to inflammatory stimuli
    • Maresz K., Carrier E.J., Ponomarev E.D., Hillard C.J., and Dittel B.N. Modulation of the cannabinoid CB2 receptor in microglial cells in response to inflammatory stimuli. J Neurochem 95 (2005) 437-445
    • (2005) J Neurochem , vol.95 , pp. 437-445
    • Maresz, K.1    Carrier, E.J.2    Ponomarev, E.D.3    Hillard, C.J.4    Dittel, B.N.5
  • 45
    • 0026623545 scopus 로고
    • Delta 9-tetrahydrocannabinol decreases cytotoxic T lymphocyte activity to herpes simplex virus type 1-infected cells
    • Fischer-Stenger K., Updegrove A.W., and Cabral G.A. Delta 9-tetrahydrocannabinol decreases cytotoxic T lymphocyte activity to herpes simplex virus type 1-infected cells. Proc Soc Exp Biol Med 200 (1992) 422-430
    • (1992) Proc Soc Exp Biol Med , vol.200 , pp. 422-430
    • Fischer-Stenger, K.1    Updegrove, A.W.2    Cabral, G.A.3
  • 46
    • 0026516862 scopus 로고
    • Suppressive effect of tetrahydrocannabinol on specific T cell subpopulations in the thymus
    • Pross S., Nakano Y., Smith J., Widen R., Rodriguez A., Newton C., et al. Suppressive effect of tetrahydrocannabinol on specific T cell subpopulations in the thymus. Thymus 19 (1992) 97-104
    • (1992) Thymus , vol.19 , pp. 97-104
    • Pross, S.1    Nakano, Y.2    Smith, J.3    Widen, R.4    Rodriguez, A.5    Newton, C.6
  • 47
    • 33749014963 scopus 로고    scopus 로고
    • Cannabinoid treatment suppresses the T-helper cell-polarizing function of mouse dendritic cells stimulated with Legionella pneumophila infection
    • Lu T., Newton C., Perkins I., Friedman H., and Klein T.W. Cannabinoid treatment suppresses the T-helper cell-polarizing function of mouse dendritic cells stimulated with Legionella pneumophila infection. J Pharmacol Exp Ther 319 (2006) 269-276
    • (2006) J Pharmacol Exp Ther , vol.319 , pp. 269-276
    • Lu, T.1    Newton, C.2    Perkins, I.3    Friedman, H.4    Klein, T.W.5
  • 48
    • 43449130045 scopus 로고    scopus 로고
    • The cannabinoid delta-9-tetrahydrocannabinol mediates inhibition of macrophage chemotaxis to RANTES/CCL5: linkage to the CB2 receptor
    • Raborn E.S., Marciano-Cabral F., Buckley N.E., Martin B.R., and Cabral G.A. The cannabinoid delta-9-tetrahydrocannabinol mediates inhibition of macrophage chemotaxis to RANTES/CCL5: linkage to the CB2 receptor. J Neuroimmune Pharmacol 3 (2008) 117-129
    • (2008) J Neuroimmune Pharmacol , vol.3 , pp. 117-129
    • Raborn, E.S.1    Marciano-Cabral, F.2    Buckley, N.E.3    Martin, B.R.4    Cabral, G.A.5
  • 49
    • 33845811458 scopus 로고    scopus 로고
    • Involvement of cannabinoid CB2 receptors in the IgE-mediated triphasic cutaneous reaction in mice
    • Ueda Y., Miyagawa N., and Wakitani K. Involvement of cannabinoid CB2 receptors in the IgE-mediated triphasic cutaneous reaction in mice. Life Sci 80 (2007) 414-419
    • (2007) Life Sci , vol.80 , pp. 414-419
    • Ueda, Y.1    Miyagawa, N.2    Wakitani, K.3
  • 50
    • 38349099590 scopus 로고    scopus 로고
    • The peripheral cannabinoid receptor knockout mice: an update
    • Buckley N.E. The peripheral cannabinoid receptor knockout mice: an update. Br J Pharmacol 153 (2008) 309-318
    • (2008) Br J Pharmacol , vol.153 , pp. 309-318
    • Buckley, N.E.1
  • 51
    • 0034641936 scopus 로고    scopus 로고
    • Apoptosis in the nervous system
    • Yuan J., and Yankner B.A. Apoptosis in the nervous system. Nature 407 (2000) 802-809
    • (2000) Nature , vol.407 , pp. 802-809
    • Yuan, J.1    Yankner, B.A.2
  • 52
    • 0027273257 scopus 로고
    • Delta-9-Tetrahydrocannabinol (THC) decreases the number of high and intermediate affinity IL-2 receptors of the IL-2 dependent cell line NKB61A2
    • Zhu W., Igarashi T., Qi Z.T., Newton C., Widen R.E., Friedman H., et al. Delta-9-Tetrahydrocannabinol (THC) decreases the number of high and intermediate affinity IL-2 receptors of the IL-2 dependent cell line NKB61A2. Int J Immunopharmacol 15 (1993) 401-408
    • (1993) Int J Immunopharmacol , vol.15 , pp. 401-408
    • Zhu, W.1    Igarashi, T.2    Qi, Z.T.3    Newton, C.4    Widen, R.E.5    Friedman, H.6
  • 53
    • 0032520649 scopus 로고    scopus 로고
    • Regulation of the cAMP cascade, gene expression and immune function by cannabinoid receptors
    • Kaminski N.E. Regulation of the cAMP cascade, gene expression and immune function by cannabinoid receptors. J Neuroimmunol 83 (1998) 124-132
    • (1998) J Neuroimmunol , vol.83 , pp. 124-132
    • Kaminski, N.E.1
  • 54
    • 0028979327 scopus 로고
    • Delta 9-Tetrahydrocannabinol modulates antigen processing by macrophages
    • McCoy K.L., Gainey D., and Cabral G.A. Delta 9-Tetrahydrocannabinol modulates antigen processing by macrophages. J Pharmacol Exp Ther 273 (1995) 1216-1223
    • (1995) J Pharmacol Exp Ther , vol.273 , pp. 1216-1223
    • McCoy, K.L.1    Gainey, D.2    Cabral, G.A.3
  • 56
    • 0034932852 scopus 로고    scopus 로고
    • Effects of the cannabimimetic fatty acid derivatives 2-arachidonoylglycerol, anandamide, palmitoylethanolamide and methanandamide upon IgE-dependent antigen-induced beta-hexosaminidase, serotonin and TNF alpha release from rat RBL-2H3 basophilic leukaemic cells
    • Granberg M., Fowler C.J., and Jacobsson S.O. Effects of the cannabimimetic fatty acid derivatives 2-arachidonoylglycerol, anandamide, palmitoylethanolamide and methanandamide upon IgE-dependent antigen-induced beta-hexosaminidase, serotonin and TNF alpha release from rat RBL-2H3 basophilic leukaemic cells. Naunyn Schmiedebergs Arch Pharmacol 364 (2001) 66-73
    • (2001) Naunyn Schmiedebergs Arch Pharmacol , vol.364 , pp. 66-73
    • Granberg, M.1    Fowler, C.J.2    Jacobsson, S.O.3
  • 57
    • 28944438774 scopus 로고    scopus 로고
    • The cannabinoid CB2 receptor selective agonist JWH133 reduces mast cell oedema in response to compound 48/80 in vivo but not the release of beta-hexosaminidase from skin slices in vitro
    • Jonsson K.O., Persson E., and Fowler C.J. The cannabinoid CB2 receptor selective agonist JWH133 reduces mast cell oedema in response to compound 48/80 in vivo but not the release of beta-hexosaminidase from skin slices in vitro. Life Sci 78 (2006) 598-606
    • (2006) Life Sci , vol.78 , pp. 598-606
    • Jonsson, K.O.1    Persson, E.2    Fowler, C.J.3
  • 58
    • 0037454135 scopus 로고    scopus 로고
    • Effects of cannabinoid receptor agonists on immunologically induced histamine release from rat peritoneal mast cells
    • Lau A.H., and Chow S.S. Effects of cannabinoid receptor agonists on immunologically induced histamine release from rat peritoneal mast cells. Eur J Pharmacol 464 (2003) 229-235
    • (2003) Eur J Pharmacol , vol.464 , pp. 229-235
    • Lau, A.H.1    Chow, S.S.2
  • 60
    • 77950501675 scopus 로고    scopus 로고
    • Anti-inflammatory potential of CB1-mediated cAMP elevation in mast cells
    • Small-Howard A.L., Shimoda L.M., Adra C.N., and Turner H. Anti-inflammatory potential of CB1-mediated cAMP elevation in mast cells. Biochem J 25 (2005) 25
    • (2005) Biochem J , vol.25 , pp. 25
    • Small-Howard, A.L.1    Shimoda, L.M.2    Adra, C.N.3    Turner, H.4
  • 61
    • 0027430992 scopus 로고
    • Structure-activity relationships for cannabinoid receptor-binding and analgesic activity: studies of bicyclic cannabinoid analogs
    • Melvin L.S., Milne G.M., Johnson M.R., Subramaniam B., Wilken G.H., and Howlett A.C. Structure-activity relationships for cannabinoid receptor-binding and analgesic activity: studies of bicyclic cannabinoid analogs. Mol Pharmacol 44 (1993) 1008-1015
    • (1993) Mol Pharmacol , vol.44 , pp. 1008-1015
    • Melvin, L.S.1    Milne, G.M.2    Johnson, M.R.3    Subramaniam, B.4    Wilken, G.H.5    Howlett, A.C.6
  • 62
    • 0033921628 scopus 로고    scopus 로고
    • Cannabinoid receptor ligands: clinical and neuropharmacological considerations, relevant to future drug discovery and development
    • Pertwee R.G. Cannabinoid receptor ligands: clinical and neuropharmacological considerations, relevant to future drug discovery and development. Expert Opin Investig Drugs 9 (2000) 1553-1571
    • (2000) Expert Opin Investig Drugs , vol.9 , pp. 1553-1571
    • Pertwee, R.G.1
  • 63
    • 33749427038 scopus 로고    scopus 로고
    • Combined cannabinoid therapy via an oromucosal spray
    • Perez J. Combined cannabinoid therapy via an oromucosal spray. Drugs Today (Barc) 42 (2006) 495-503
    • (2006) Drugs Today (Barc) , vol.42 , pp. 495-503
    • Perez, J.1
  • 64
    • 33645347973 scopus 로고    scopus 로고
    • Cannabinoids in medicine: a review of their therapeutic potential
    • Ben Amar M. Cannabinoids in medicine: a review of their therapeutic potential. J Ethnopharmacol 105 (2006) 1-25
    • (2006) J Ethnopharmacol , vol.105 , pp. 1-25
    • Ben Amar, M.1
  • 66
    • 0031473751 scopus 로고    scopus 로고
    • Effect of the cannabinoid receptor SPECT agent, AM 281, on hippocampal acetylcholine release from rat brain slices
    • Gifford A.N., Tang Y., Gatley S.J., Volkow N.D., Lan R., and Makriyannis A. Effect of the cannabinoid receptor SPECT agent, AM 281, on hippocampal acetylcholine release from rat brain slices. Neurosci Lett 238 (1997) 84-86
    • (1997) Neurosci Lett , vol.238 , pp. 84-86
    • Gifford, A.N.1    Tang, Y.2    Gatley, S.J.3    Volkow, N.D.4    Lan, R.5    Makriyannis, A.6
  • 68
    • 0028129936 scopus 로고
    • SR141716A, a potent and selective antagonist of the brain cannabinoid receptor
    • Rinaldi-Carmona M., Barth F., Heaulme M., Shire D., Calandra B., Congy C., et al. SR141716A, a potent and selective antagonist of the brain cannabinoid receptor. FEBS Lett 350 (1994) 240-244
    • (1994) FEBS Lett , vol.350 , pp. 240-244
    • Rinaldi-Carmona, M.1    Barth, F.2    Heaulme, M.3    Shire, D.4    Calandra, B.5    Congy, C.6
  • 70
    • 63749088629 scopus 로고    scopus 로고
    • Obesity, the endocannabinoid system, and bias arising from pharmaceutical sponsorship
    • McPartland J.M. Obesity, the endocannabinoid system, and bias arising from pharmaceutical sponsorship. PLoS ONE 4 (2009) e5092
    • (2009) PLoS ONE , vol.4
    • McPartland, J.M.1
  • 71
    • 67650504086 scopus 로고    scopus 로고
    • The psychiatric side-effects of rimonabant
    • Moreira F.A., and Crippa J.A. The psychiatric side-effects of rimonabant. Rev Bras Psiquiatr 31 (2009) 145-153
    • (2009) Rev Bras Psiquiatr , vol.31 , pp. 145-153
    • Moreira, F.A.1    Crippa, J.A.2
  • 72
    • 61649089261 scopus 로고    scopus 로고
    • Central side-effects of therapies based on CB1 cannabinoid receptor agonists and antagonists: focus on anxiety and depression
    • Moreira F.A., Grieb M., and Lutz B. Central side-effects of therapies based on CB1 cannabinoid receptor agonists and antagonists: focus on anxiety and depression. Best Pract Res Clin Endocrinol Metab 23 (2009) 133-144
    • (2009) Best Pract Res Clin Endocrinol Metab , vol.23 , pp. 133-144
    • Moreira, F.A.1    Grieb, M.2    Lutz, B.3
  • 73
    • 0036769551 scopus 로고    scopus 로고
    • SR144528 as inverse agonist of CB2 cannabinoid receptor
    • Rhee M.H., and Kim S.K. SR144528 as inverse agonist of CB2 cannabinoid receptor. J Vet Sci 3 (2002) 179-184
    • (2002) J Vet Sci , vol.3 , pp. 179-184
    • Rhee, M.H.1    Kim, S.K.2
  • 76
    • 0034594905 scopus 로고    scopus 로고
    • Cannabinoids control spasticity and tremor in a multiple sclerosis model
    • Baker D., Pryce G., Croxford J.L., Brown P., Pertwee R.G., Huffman J.W., et al. Cannabinoids control spasticity and tremor in a multiple sclerosis model. Nature 404 (2000) 84-87
    • (2000) Nature , vol.404 , pp. 84-87
    • Baker, D.1    Pryce, G.2    Croxford, J.L.3    Brown, P.4    Pertwee, R.G.5    Huffman, J.W.6
  • 79
    • 67649881952 scopus 로고    scopus 로고
    • Cannabinoid system in neurodegeneration: new perspectives in Alzheimer's disease
    • Campillo N.E., and Paez J.A. Cannabinoid system in neurodegeneration: new perspectives in Alzheimer's disease. Mini Rev Med Chem 9 (2009) 539-559
    • (2009) Mini Rev Med Chem , vol.9 , pp. 539-559
    • Campillo, N.E.1    Paez, J.A.2
  • 81
    • 67651050055 scopus 로고    scopus 로고
    • The endocannabinoid system in neuropathological states
    • Orgado J.M., Fernandez-Ruiz J., and Romero J. The endocannabinoid system in neuropathological states. Int Rev Psychiatry 21 (2009) 172-180
    • (2009) Int Rev Psychiatry , vol.21 , pp. 172-180
    • Orgado, J.M.1    Fernandez-Ruiz, J.2    Romero, J.3
  • 84
    • 70249128716 scopus 로고    scopus 로고
    • Substance misuse and early psychosis
    • Tucker P. Substance misuse and early psychosis. Australas Psychiatry 17 (2009) 291-294
    • (2009) Australas Psychiatry , vol.17 , pp. 291-294
    • Tucker, P.1
  • 86
    • 35948986314 scopus 로고    scopus 로고
    • Genotype effects of CHRNA7, CNR1 and COMT in schizophrenia: interactions with tobacco and cannabis use
    • Zammit S., Spurlock G., Williams H., Norton N., Williams N., O'Donovan M.C., et al. Genotype effects of CHRNA7, CNR1 and COMT in schizophrenia: interactions with tobacco and cannabis use. Br J Psychiatry 191 (2007) 402-407
    • (2007) Br J Psychiatry , vol.191 , pp. 402-407
    • Zammit, S.1    Spurlock, G.2    Williams, H.3    Norton, N.4    Williams, N.5    O'Donovan, M.C.6
  • 87
    • 0035826433 scopus 로고    scopus 로고
    • Association study between cannabinoid receptor gene (CNR1) and pathogenesis and psychotic symptoms of mood disorders
    • Tsai S.J., Wang Y.C., and Hong C.J. Association study between cannabinoid receptor gene (CNR1) and pathogenesis and psychotic symptoms of mood disorders. Am J Med Genet 105 (2001) 219-221
    • (2001) Am J Med Genet , vol.105 , pp. 219-221
    • Tsai, S.J.1    Wang, Y.C.2    Hong, C.J.3
  • 88
    • 0029071194 scopus 로고
    • Cannabinoids modulate voltage sensitive potassium A-current in hippocampal neurons via a cAMP-dependent process
    • Deadwyler S.A., Hampson R.E., Mu J., Whyte A., and Childers S. Cannabinoids modulate voltage sensitive potassium A-current in hippocampal neurons via a cAMP-dependent process. J Pharmacol Exp Ther 273 (1995) 734-743
    • (1995) J Pharmacol Exp Ther , vol.273 , pp. 734-743
    • Deadwyler, S.A.1    Hampson, R.E.2    Mu, J.3    Whyte, A.4    Childers, S.5
  • 90
    • 1642430679 scopus 로고    scopus 로고
    • Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1
    • Electronic publication 2004 Jan 7
    • Jordt S.E., Bautista D.M., Chuang H.H., McKemy D.D., Zygmunt P.M., Hogestatt E.D., et al. Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1. Nature 427 (2004) 260-265 Electronic publication 2004 Jan 7
    • (2004) Nature , vol.427 , pp. 260-265
    • Jordt, S.E.1    Bautista, D.M.2    Chuang, H.H.3    McKemy, D.D.4    Zygmunt, P.M.5    Hogestatt, E.D.6
  • 91
    • 0344873175 scopus 로고    scopus 로고
    • Anandamide and vanilloid TRPV1 receptors
    • Electronic publication 2003 Sep 29
    • Ross R.A. Anandamide and vanilloid TRPV1 receptors. Br J Pharmacol 140 (2003) 790-801 Electronic publication 2003 Sep 29
    • (2003) Br J Pharmacol , vol.140 , pp. 790-801
    • Ross, R.A.1
  • 93
    • 0344505201 scopus 로고    scopus 로고
    • Drugs and immunity: cannabinoids and their role in decreased resistance to infectious disease
    • Cabral G.A., and Dove Pettit D.A. Drugs and immunity: cannabinoids and their role in decreased resistance to infectious disease. J Neuroimmunol 83 (1998) 116-123
    • (1998) J Neuroimmunol , vol.83 , pp. 116-123
    • Cabral, G.A.1    Dove Pettit, D.A.2
  • 94
    • 42349104678 scopus 로고    scopus 로고
    • Cannabinomimetic control of mast cell mediator release: new perspective in chronic inflammation
    • De Filippis D., D'Amico A., and Iuvone T. Cannabinomimetic control of mast cell mediator release: new perspective in chronic inflammation. J Neuroendocrinol 20 Suppl 1 (2008) 20-25
    • (2008) J Neuroendocrinol , vol.20 , Issue.SUPPL. 1 , pp. 20-25
    • De Filippis, D.1    D'Amico, A.2    Iuvone, T.3
  • 96
    • 26044461277 scopus 로고    scopus 로고
    • Endocannabinoids in the regulation of appetite and body weight
    • Kirkham T.C. Endocannabinoids in the regulation of appetite and body weight. Behav Pharmacol 16 (2005) 297-313
    • (2005) Behav Pharmacol , vol.16 , pp. 297-313
    • Kirkham, T.C.1
  • 98
    • 56449095685 scopus 로고    scopus 로고
    • Role of endocannabinoids and their analogues in obesity and eating disorders
    • Gaetani S., Kaye W.H., Cuomo V., and Piomelli D. Role of endocannabinoids and their analogues in obesity and eating disorders. Eat Weight Disord 13 (2008) e42-e48
    • (2008) Eat Weight Disord , vol.13
    • Gaetani, S.1    Kaye, W.H.2    Cuomo, V.3    Piomelli, D.4
  • 99
    • 24944527344 scopus 로고    scopus 로고
    • Cancer cachexia and immunomodulation
    • Myrianthefs P.M., and Batistaki C. Cancer cachexia and immunomodulation. J BUON 10 (2005) 181-188
    • (2005) J BUON , vol.10 , pp. 181-188
    • Myrianthefs, P.M.1    Batistaki, C.2
  • 101
    • 0022481918 scopus 로고
    • Cannabis psychosis
    • Ghodse A.H. Cannabis psychosis. Br J Addict 81 (1986) 473-478
    • (1986) Br J Addict , vol.81 , pp. 473-478
    • Ghodse, A.H.1
  • 102
    • 57049112166 scopus 로고    scopus 로고
    • Cannabis use and the risk of developing a psychotic disorder
    • Hall W., and Degenhardt L. Cannabis use and the risk of developing a psychotic disorder. World Psychiatry 7 (2008) 68-71
    • (2008) World Psychiatry , vol.7 , pp. 68-71
    • Hall, W.1    Degenhardt, L.2
  • 103
    • 44549087417 scopus 로고    scopus 로고
    • Blunted psychotomimetic and amnestic effects of delta-9-tetrahydrocannabinol in frequent users of cannabis
    • D'Souza D.C., Ranganathan M., Braley G., Gueorguieva R., Zimolo Z., Cooper T., et al. Blunted psychotomimetic and amnestic effects of delta-9-tetrahydrocannabinol in frequent users of cannabis. Neuropsychopharmacology 33 (2008) 2505-2516
    • (2008) Neuropsychopharmacology , vol.33 , pp. 2505-2516
    • D'Souza, D.C.1    Ranganathan, M.2    Braley, G.3    Gueorguieva, R.4    Zimolo, Z.5    Cooper, T.6
  • 104
    • 4243057291 scopus 로고    scopus 로고
    • Marijuana-induced transient global amnesia
    • Shukla P.C., and Moore U.B. Marijuana-induced transient global amnesia. South Med J 97 (2004) 782-784
    • (2004) South Med J , vol.97 , pp. 782-784
    • Shukla, P.C.1    Moore, U.B.2
  • 106
    • 37249060841 scopus 로고    scopus 로고
    • Work-related contact urticaria to Cannabis sativa
    • Williams C., Thompstone J., and Wilkinson M. Work-related contact urticaria to Cannabis sativa. Contact Dermat 58 (2008) 62-63
    • (2008) Contact Dermat , vol.58 , pp. 62-63
    • Williams, C.1    Thompstone, J.2    Wilkinson, M.3
  • 107
    • 46049102056 scopus 로고    scopus 로고
    • The adverse effects of cannabinoids: implications for use of medical marijuana
    • Degenhardt L., and Hall W.D. The adverse effects of cannabinoids: implications for use of medical marijuana. Cmaj 178 (2008) 1685-1686
    • (2008) Cmaj , vol.178 , pp. 1685-1686
    • Degenhardt, L.1    Hall, W.D.2
  • 108
    • 39149123169 scopus 로고    scopus 로고
    • Recreational drug toxicity
    • Hill S., and Thomas S.H. Recreational drug toxicity. Clin Med 8 (2008) 99-103
    • (2008) Clin Med , vol.8 , pp. 99-103
    • Hill, S.1    Thomas, S.H.2
  • 109
    • 42249114663 scopus 로고    scopus 로고
    • Long lasting consequences of cannabis exposure in adolescence
    • Rubino T., and Parolaro D. Long lasting consequences of cannabis exposure in adolescence. Mol Cell Endocrinol 286 (2008) S108-S113
    • (2008) Mol Cell Endocrinol , vol.286
    • Rubino, T.1    Parolaro, D.2
  • 110
    • 23844510064 scopus 로고    scopus 로고
    • Smoked marijuana as a cause of lung injury
    • Tashkin D.P. Smoked marijuana as a cause of lung injury. Monaldi Arch Chest Dis 63 (2005) 93-100
    • (2005) Monaldi Arch Chest Dis , vol.63 , pp. 93-100
    • Tashkin, D.P.1
  • 111
    • 0141677644 scopus 로고    scopus 로고
    • Short-term effects of cannabinoids in patients with HIV-1 infection: a randomized, placebo-controlled clinical trial
    • Abrams D.I., Hilton J.F., Leiser R.J., Shade S.B., Elbeik T.A., Aweeka F.T., et al. Short-term effects of cannabinoids in patients with HIV-1 infection: a randomized, placebo-controlled clinical trial. Ann Intern Med 139 (2003) 258-266
    • (2003) Ann Intern Med , vol.139 , pp. 258-266
    • Abrams, D.I.1    Hilton, J.F.2    Leiser, R.J.3    Shade, S.B.4    Elbeik, T.A.5    Aweeka, F.T.6
  • 113
    • 0024344109 scopus 로고
    • No evidence for a role of alcohol or other psychoactive drugs in accelerating immunodeficiency in HIV-1-positive individuals. A report from the Multicenter AIDS Cohort Study
    • Kaslow R.A., Blackwelder W.C., Ostrow D.G., Yerg D., Palenicek J., Coulson A.H., et al. No evidence for a role of alcohol or other psychoactive drugs in accelerating immunodeficiency in HIV-1-positive individuals. A report from the Multicenter AIDS Cohort Study. JAMA 261 (1989) 3424-3429
    • (1989) JAMA , vol.261 , pp. 3424-3429
    • Kaslow, R.A.1    Blackwelder, W.C.2    Ostrow, D.G.3    Yerg, D.4    Palenicek, J.5    Coulson, A.H.6
  • 114
    • 34249036065 scopus 로고    scopus 로고
    • Combined immunomodulating properties of 3, 4-methylenedioxymethamphetamine (MDMA) and cannabis in humans
    • Pacifici R., Zuccaro P., Farre M., Poudevida S., Abanades S., Pichini S., et al. Combined immunomodulating properties of 3, 4-methylenedioxymethamphetamine (MDMA) and cannabis in humans. Addiction 102 (2007) 931-936
    • (2007) Addiction , vol.102 , pp. 931-936
    • Pacifici, R.1    Zuccaro, P.2    Farre, M.3    Poudevida, S.4    Abanades, S.5    Pichini, S.6
  • 116
    • 0021824944 scopus 로고
    • Health consequences of acute and chronic marihuana use
    • Maykut M.O. Health consequences of acute and chronic marihuana use. Prog Neuropsychopharmacol Biol Psychiatry 9 (1985) 209-238
    • (1985) Prog Neuropsychopharmacol Biol Psychiatry , vol.9 , pp. 209-238
    • Maykut, M.O.1
  • 117
  • 118
    • 4644245912 scopus 로고    scopus 로고
    • Immunology of HIV-filling in the details
    • quiz 83
    • Buckland M.S., and Pinching A.J. Immunology of HIV-filling in the details. Int J STD AIDS 15 (2004) 574-582 quiz 83
    • (2004) Int J STD AIDS , vol.15 , pp. 574-582
    • Buckland, M.S.1    Pinching, A.J.2
  • 119
    • 0026653197 scopus 로고
    • Immunological abnormalities in the natural history of HIV infection: mechanisms and clinical relevance
    • Miedema F. Immunological abnormalities in the natural history of HIV infection: mechanisms and clinical relevance. Immunodefic Rev 3 (1992) 173-193
    • (1992) Immunodefic Rev , vol.3 , pp. 173-193
    • Miedema, F.1
  • 120
    • 0025900507 scopus 로고
    • HIV/AIDS pathogenesis and treatment: new twists and turns
    • Pinching A.J. HIV/AIDS pathogenesis and treatment: new twists and turns. Curr Opin Immunol 3 (1991) 537-542
    • (1991) Curr Opin Immunol , vol.3 , pp. 537-542
    • Pinching, A.J.1
  • 121
    • 33644824945 scopus 로고    scopus 로고
    • The cancer cachexia syndrome: a review of metabolic and clinical manifestations
    • Esper D.H., and Harb W.A. The cancer cachexia syndrome: a review of metabolic and clinical manifestations. Nutr Clin Pract 20 (2005) 369-376
    • (2005) Nutr Clin Pract , vol.20 , pp. 369-376
    • Esper, D.H.1    Harb, W.A.2
  • 123
    • 0035666553 scopus 로고    scopus 로고
    • Is obesity an inflammatory condition?
    • Das U.N. Is obesity an inflammatory condition?. Nutrition 17 (2001) 953-966
    • (2001) Nutrition , vol.17 , pp. 953-966
    • Das, U.N.1
  • 124
    • 3242889982 scopus 로고    scopus 로고
    • Systemic low-grade inflammation is related to both circulating and adipose tissue TNFalpha, leptin and IL-6 levels in obese women
    • Maachi M., Pieroni L., Bruckert E., Jardel C., Fellahi S., Hainque B., et al. Systemic low-grade inflammation is related to both circulating and adipose tissue TNFalpha, leptin and IL-6 levels in obese women. Int J Obes Relat Metab Disord 28 (2004) 993-997
    • (2004) Int J Obes Relat Metab Disord , vol.28 , pp. 993-997
    • Maachi, M.1    Pieroni, L.2    Bruckert, E.3    Jardel, C.4    Fellahi, S.5    Hainque, B.6
  • 125
    • 67650218498 scopus 로고    scopus 로고
    • Inflammatory components of adipose tissue as target for treatment of metabolic syndrome
    • Yu R., Kim C.S., and Kang J.H. Inflammatory components of adipose tissue as target for treatment of metabolic syndrome. Forum Nutr 61 (2009) 95-103
    • (2009) Forum Nutr , vol.61 , pp. 95-103
    • Yu, R.1    Kim, C.S.2    Kang, J.H.3
  • 126
    • 34548487258 scopus 로고    scopus 로고
    • The link between the epidemics of obesity and allergic diseases: does obesity induce decreased immune tolerance?
    • Hersoug L.G., and Linneberg A. The link between the epidemics of obesity and allergic diseases: does obesity induce decreased immune tolerance?. Allergy 62 (2007) 1205-1213
    • (2007) Allergy , vol.62 , pp. 1205-1213
    • Hersoug, L.G.1    Linneberg, A.2
  • 127
    • 84884474728 scopus 로고    scopus 로고
    • Pharmacological actions of cannabinoids
    • Pertwee R.G. Pharmacological actions of cannabinoids. Handb Exp Pharmacol (2005) 1-51
    • (2005) Handb Exp Pharmacol , pp. 1-51
    • Pertwee, R.G.1
  • 128
    • 0041842648 scopus 로고    scopus 로고
    • Endogenous interleukin-1 receptor antagonist mediates anti-inflammatory and neuroprotective actions of cannabinoids in neurones and glia
    • Molina-Holgado F., Pinteaux E., Moore J., Molina-Holgado E., Gibson R.M., Guaza C., and Rothwell N.J. Endogenous interleukin-1 receptor antagonist mediates anti-inflammatory and neuroprotective actions of cannabinoids in neurones and glia. J Neurosci 23 (2003) 6470-6474
    • (2003) J Neurosci , vol.23 , pp. 6470-6474
    • Molina-Holgado, F.1    Pinteaux, E.2    Moore, J.3    Molina-Holgado, E.4    Gibson, R.M.5    Guaza, C.6    Rothwell, N.J.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.