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Volumn 277, Issue 8, 2010, Pages 1790-1804

Mixed lineage leukemia: Roles in gene expression, hormone signaling and mRNA processing

Author keywords

Epigenetics; Estrogen receptor; Gene expression; Histone methyltransferase; Hormone signaling; Mixed lineage leukemia; MRNA processing; NR box; Nuclear receptor; SET domain

Indexed keywords

ACTIVATING SIGNAL COINTEGRATOR 2 COMPLEX; CELL NUCLEUS RECEPTOR; HISTONE H3; HISTONE METHYLTRANSFERASE; HOX PROTEIN; LIVER X RECEPTOR; MIXED LINEAGE LEUKEMIA PROTEIN; MIXED LINEAGE LEUKEMIA PROTEIN 1; MIXED LINEAGE LEUKEMIA PROTEIN 2; MIXED LINEAGE LEUKEMIA PROTEIN 3; MIXED LINEAGE LEUKEMIA PROTEIN 4; MIXED LINEAGE LEUKEMIA PROTEIN 5; PROTEIN SET1A; PROTEIN SET1B; RETINOIC ACID RECEPTOR; RETINOIC ACID RECEPTOR 2; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR E2F2; TRANSCRIPTION FACTOR E2F3; TRANSCRIPTION FACTOR E2F4; TRANSCRIPTION FACTOR E2F5; TRANSCRIPTION FACTOR HOXA10; TRANSCRIPTION FACTOR HOXA7; TRANSCRIPTION FACTOR HOXA9; TRANSCRIPTION FACTOR HOXC13; UNCLASSIFIED DRUG;

EID: 77950475617     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2010.07606.x     Document Type: Short Survey
Times cited : (114)

References (92)
  • 1
    • 0037154982 scopus 로고    scopus 로고
    • A unified theory of gene expression
    • Orphanides G Reinberg D (2002) A unified theory of gene expression. Cell 108, 439 451.
    • (2002) Cell , vol.108 , pp. 439-451
    • Orphanides, G.1    Reinberg, D.2
  • 2
    • 1042300237 scopus 로고    scopus 로고
    • Histone methylation: Recognizing the methyl mark
    • Bannister AJ Kouzarides T (2004) Histone methylation: recognizing the methyl mark. Methods Enzymol 376, 269 288.
    • (2004) Methods Enzymol , vol.376 , pp. 269-288
    • Bannister, A.J.1    Kouzarides, T.2
  • 3
    • 35848951163 scopus 로고    scopus 로고
    • Covalent modifications of histones during development and disease pathogenesis
    • Bhaumik SR, Smith E Shilatifard A (2007) Covalent modifications of histones during development and disease pathogenesis. Nat Struct Mol Biol 14, 1008 1016.
    • (2007) Nat Struct Mol Biol , vol.14 , pp. 1008-1016
    • Bhaumik, S.R.1    Smith, E.2    Shilatifard, A.3
  • 4
    • 77950462621 scopus 로고    scopus 로고
    • Mixed lineage leukemia: Histone H3 lysine 4 methyltransferases from yeast to human
    • doi
    • Malik S Bhaumik SR (2010) Mixed lineage leukemia: histone H3 lysine 4 methyltransferases from yeast to human. FEBS J doi :.
    • (2010) FEBS J
    • Malik, S.1    Bhaumik, S.R.2
  • 6
    • 44649177124 scopus 로고    scopus 로고
    • Activating signal cointegrator-2 is an essential adaptor to recruit histone H3 lysine 4 methyltransferases MLL3 and MLL4 to the liver X receptors
    • Lee S, Lee J, Lee SK Lee JW (2008) Activating signal cointegrator-2 is an essential adaptor to recruit histone H3 lysine 4 methyltransferases MLL3 and MLL4 to the liver X receptors. Mol Endocrinol 22, 1312 1319.
    • (2008) Mol Endocrinol , vol.22 , pp. 1312-1319
    • Lee, S.1    Lee, J.2    Lee, S.K.3    Lee, J.W.4
  • 7
    • 77950468810 scopus 로고    scopus 로고
    • Mixed lineage leukemia: Roles in human malignancies and potential therapy
    • doi
    • Marschalek R (2010) Mixed lineage leukemia: roles in human malignancies and potential therapy. FEBS J doi :.
    • (2010) FEBS J
    • Marschalek, R.1
  • 9
    • 27744524941 scopus 로고    scopus 로고
    • Targeting MLL-AF4 with short interfering RNAs inhibits clonogenicity and engraftment of t(4;11)-positive human leukemic cells
    • Thomas M, Gessner A, Vornlocher HP, Hadwiger P, Greil J Heidenreich O (2005) Targeting MLL-AF4 with short interfering RNAs inhibits clonogenicity and engraftment of t(4;11)-positive human leukemic cells. Blood 106, 3559 3566.
    • (2005) Blood , vol.106 , pp. 3559-3566
    • Thomas, M.1    Gessner, A.2    Vornlocher, H.P.3    Hadwiger, P.4    Greil, J.5    Heidenreich, O.6
  • 10
    • 33645214191 scopus 로고    scopus 로고
    • The mechanism of hematopoietic progenitor cell immortalization by MLL-ENL
    • Horton SJ Williams O (2006) The mechanism of hematopoietic progenitor cell immortalization by MLL-ENL. Cell Cycle 5, 360 362.
    • (2006) Cell Cycle , vol.5 , pp. 360-362
    • Horton, S.J.1    Williams, O.2
  • 11
    • 4644220954 scopus 로고    scopus 로고
    • MLL: A histone methyltransferase disrupted in leukemia
    • Hess JL (2004) MLL: a histone methyltransferase disrupted in leukemia. Trends Mol Med 10, 500 507.
    • (2004) Trends Mol Med , vol.10 , pp. 500-507
    • Hess, J.L.1
  • 12
    • 39449088247 scopus 로고    scopus 로고
    • Human CpG binding protein interacts with MLL1, MLL2 and hSet1 and regulates Hox gene expression
    • Ansari KI, Mishra BP Mandal SS (2008) Human CpG binding protein interacts with MLL1, MLL2 and hSet1 and regulates Hox gene expression. Biochim Biophys Acta 1779, 66 73.
    • (2008) Biochim Biophys Acta , vol.1779 , pp. 66-73
    • Ansari, K.I.1    Mishra, B.P.2    Mandal, S.S.3
  • 17
    • 0027953771 scopus 로고
    • Hox genes in vertebrate development
    • Krumlauf R (1994) Hox genes in vertebrate development. Cell 78, 191 201.
    • (1994) Cell , vol.78 , pp. 191-201
    • Krumlauf, R.1
  • 18
    • 0032168459 scopus 로고    scopus 로고
    • MLL, a mammalian trithorax-group gene, functions as a transcriptional maintenance factor in morphogenesis
    • Yu BD, Hanson RD, Hess JL, Horning SE Korsmeyer SJ (1998) MLL, a mammalian trithorax-group gene, functions as a transcriptional maintenance factor in morphogenesis. Proc Natl Acad Sci USA 95, 10632 10636.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 10632-10636
    • Yu, B.D.1    Hanson, R.D.2    Hess, J.L.3    Horning, S.E.4    Korsmeyer, S.J.5
  • 19
    • 0028869112 scopus 로고
    • Altered Hox expression and segmental identity in Mll-mutant mice
    • Yu BD, Hess JL, Horning SE, Brown GA Korsmeyer SJ (1995) Altered Hox expression and segmental identity in Mll-mutant mice. Nature 378, 505 508.
    • (1995) Nature , vol.378 , pp. 505-508
    • Yu, B.D.1    Hess, J.L.2    Horning, S.E.3    Brown, G.A.4    Korsmeyer, S.J.5
  • 20
    • 0032126677 scopus 로고    scopus 로고
    • Growth disturbance in fetal liver hematopoiesis of Mll-mutant mice
    • Yagi H, Deguchi K, Aono A, Tani Y, Kishimoto T Komori T (1998) Growth disturbance in fetal liver hematopoiesis of Mll-mutant mice. Blood 92, 108 117.
    • (1998) Blood , vol.92 , pp. 108-117
    • Yagi, H.1    Deguchi, K.2    Aono, A.3    Tani, Y.4    Kishimoto, T.5    Komori, T.6
  • 21
    • 0030954681 scopus 로고    scopus 로고
    • Defects in yolk sac hematopoiesis in Mll-null embryos
    • Hess JL, Yu BD, Li B, Hanson R Korsmeyer SJ (1997) Defects in yolk sac hematopoiesis in Mll-null embryos. Blood 90, 1799 1806.
    • (1997) Blood , vol.90 , pp. 1799-1806
    • Hess, J.L.1    Yu, B.D.2    Li, B.3    Hanson, R.4    Korsmeyer, S.J.5
  • 22
    • 33646230318 scopus 로고    scopus 로고
    • Histone and DNA methylation defects at Hox genes in mice expressing a SET domain-truncated form of Mll
    • Terranova R, Agherbi H, Boned A, Meresse S Djabali M (2006) Histone and DNA methylation defects at Hox genes in mice expressing a SET domain-truncated form of Mll. Proc Natl Acad Sci USA 103, 6629 6634.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 6629-6634
    • Terranova, R.1    Agherbi, H.2    Boned, A.3    Meresse, S.4    Djabali, M.5
  • 23
    • 34548462072 scopus 로고    scopus 로고
    • Unique and independent roles for MLL in adult hematopoietic stem cells and progenitors
    • Jude CD, Climer L, Xu D, Artinger E, Fisher JK Ernst P (2007) Unique and independent roles for MLL in adult hematopoietic stem cells and progenitors. Cell Stem Cell 1, 324 337.
    • (2007) Cell Stem Cell , vol.1 , pp. 324-337
    • Jude, C.D.1    Climer, L.2    Xu, D.3    Artinger, E.4    Fisher, J.K.5    Ernst, P.6
  • 27
    • 0035839952 scopus 로고    scopus 로고
    • Molecular mechanisms of leukemogenesis mediated by MLL fusion proteins
    • Ayton PM Cleary ML (2001) Molecular mechanisms of leukemogenesis mediated by MLL fusion proteins. Oncogene 20, 5695 5707.
    • (2001) Oncogene , vol.20 , pp. 5695-5707
    • Ayton, P.M.1    Cleary, M.L.2
  • 28
    • 0041370095 scopus 로고    scopus 로고
    • Transformation of myeloid progenitors by MLL oncoproteins is dependent on Hoxa7 and Hoxa9
    • Ayton PM Cleary ML (2003) Transformation of myeloid progenitors by MLL oncoproteins is dependent on Hoxa7 and Hoxa9. Genes Dev 17, 2298 2307.
    • (2003) Genes Dev , vol.17 , pp. 2298-2307
    • Ayton, P.M.1    Cleary, M.L.2
  • 29
    • 0037215399 scopus 로고    scopus 로고
    • Proteolytic cleavage of MLL generates a complex of N- and C-terminal fragments that confers protein stability and subnuclear localization
    • Hsieh JJD, Ernst P, Erdjument-Bromage H, Tempst P Korsmeyer SJ (2003) Proteolytic cleavage of MLL generates a complex of N- and C-terminal fragments that confers protein stability and subnuclear localization. Mol Cell Biol 23, 186 194.
    • (2003) Mol Cell Biol , vol.23 , pp. 186-194
    • Hsieh, J.J.D.1    Ernst, P.2    Erdjument-Bromage, H.3    Tempst, P.4    Korsmeyer, S.J.5
  • 31
    • 68949141617 scopus 로고    scopus 로고
    • MLL associates with telomeres and regulates telomeric repeat-containing RNA transcription
    • Caslini C, Connelly JA, Serna A, Broccoli D Hess JL (2009) MLL associates with telomeres and regulates telomeric repeat-containing RNA transcription. Mol Cell Biol 29, 4519 4526.
    • (2009) Mol Cell Biol , vol.29 , pp. 4519-4526
    • Caslini, C.1    Connelly, J.A.2    Serna, A.3    Broccoli, D.4    Hess, J.L.5
  • 32
    • 70349766918 scopus 로고    scopus 로고
    • Ascom controls farnesoid X receptor transactivation through its associated histone H3 lysine 4 methyltransferase activity
    • Kim DH, Lee J, Lee B Lee JW (2009) Ascom controls farnesoid X receptor transactivation through its associated histone H3 lysine 4 methyltransferase activity. Mol Endocrinol 23, 1556 1562.
    • (2009) Mol Endocrinol , vol.23 , pp. 1556-1562
    • Kim, D.H.1    Lee, J.2    Lee, B.3    Lee, J.W.4
  • 37
    • 71949107301 scopus 로고    scopus 로고
    • Global analysis of H3K4 methylation defines MLL family member targets and points to a role for MLL1-mediated H3K4 methylation in the regulation of transcriptional initiation by RNA polymerase II
    • Wang P, Lin C, Smith ER, Guo H, Sanderson BW, Wu M, Gogol M, Alexander T, Seidel C, Wiedemann LM et al. (2009) Global analysis of H3K4 methylation defines MLL family member targets and points to a role for MLL1-mediated H3K4 methylation in the regulation of transcriptional initiation by RNA polymerase II. Mol Cell Biol 29, 6074 6085.
    • (2009) Mol Cell Biol , vol.29 , pp. 6074-6085
    • Wang, P.1    Lin, C.2    Smith, E.R.3    Guo, H.4    Sanderson, B.W.5    Wu, M.6    Gogol, M.7    Alexander, T.8    Seidel, C.9    Wiedemann, L.M.10
  • 39
    • 34250823511 scopus 로고    scopus 로고
    • E2F activation of S phase promoters via association with HCF-1 and the MLL family of histone H3K4 methyltransferases
    • Tyagi S, Chabes AL, Wysocka J Herr W (2007) E2F activation of S phase promoters via association with HCF-1 and the MLL family of histone H3K4 methyltransferases. Mol Cell 27, 107 119.
    • (2007) Mol Cell , vol.27 , pp. 107-119
    • Tyagi, S.1    Chabes, A.L.2    Wysocka, J.3    Herr, W.4
  • 40
    • 61349113967 scopus 로고    scopus 로고
    • Dynamic association of MLL1, H3K4 trimethylation with chromatin and Hox gene expression during the cell cycle
    • Mishra BP, Ansari KI Mandal SS (2009) Dynamic association of MLL1, H3K4 trimethylation with chromatin and Hox gene expression during the cell cycle. FEBS J 276, 1629 1640.
    • (2009) FEBS J , vol.276 , pp. 1629-1640
    • Mishra, B.P.1    Ansari, K.I.2    Mandal, S.S.3
  • 41
    • 66249118002 scopus 로고    scopus 로고
    • Overexpression of human histone methylase MLL1 upon exposure to a food contaminant mycotoxin, deoxynivalenol
    • Ansari KI, Hussain I, Das HK Mandal SS (2009) Overexpression of human histone methylase MLL1 upon exposure to a food contaminant mycotoxin, deoxynivalenol. FEBS J 276, 3299 3307.
    • (2009) FEBS J , vol.276 , pp. 3299-3307
    • Ansari, K.I.1    Hussain, I.2    Das, H.K.3    Mandal, S.S.4
  • 44
    • 17144460311 scopus 로고
    • Effect of estrogen on the blast transformation of lymphocytes and interleukin-2 production in lupus erythematosus
    • Pozsonyi T, Jakab L, Jakab LA, Onody K, Cseh K Kalabay L (1992) Effect of estrogen on the blast transformation of lymphocytes and interleukin-2 production in lupus erythematosus. Orv Hetil 133, 1167 1171.
    • (1992) Orv Hetil , vol.133 , pp. 1167-1171
    • Pozsonyi, T.1    Jakab, L.2    Jakab, L.A.3    Onody, K.4    Cseh, K.5    Kalabay, L.6
  • 45
    • 0035449377 scopus 로고    scopus 로고
    • A homeotic mutation in the trithorax SET domain impedes histone binding
    • Katsani KR, Arredondo JJ, Kal AJ Verrijzer CP (2001) A homeotic mutation in the trithorax SET domain impedes histone binding. Genes Dev 15, 2197 2202.
    • (2001) Genes Dev , vol.15 , pp. 2197-2202
    • Katsani, K.R.1    Arredondo, J.J.2    Kal, A.J.3    Verrijzer, C.P.4
  • 46
    • 69949171492 scopus 로고    scopus 로고
    • On the mechanism of multiple lysine methylation by the human mixed lineage leukemia protein-1 (MLL1) core complex
    • Patel A, Dharmarajan V, Vought VE Cosgrove MS (2009) On the mechanism of multiple lysine methylation by the human mixed lineage leukemia protein-1 (MLL1) core complex. J Biol Chem 284, 24242 24256.
    • (2009) J Biol Chem , vol.284 , pp. 24242-24256
    • Patel, A.1    Dharmarajan, V.2    Vought, V.E.3    Cosgrove, M.S.4
  • 47
    • 0038374526 scopus 로고    scopus 로고
    • Transcriptional elongation by RNA polymerase II and histone methylation
    • DOI 10.1074/jbc.R300014200
    • Gerber M Shilatifard A (2003) Transcriptional elongation by RNA polymerase II and histone methylation. J Biol Chem 278, 26303 26306. (Pubitemid 36876764)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.29 , pp. 26303-26306
    • Gerber, M.1    Shilatifard, A.2
  • 48
    • 0035102477 scopus 로고    scopus 로고
    • MLL and CREB bind cooperatively to the nuclear coactivator CREB-binding protein
    • Ernst P, Wang J, Huang M, Goodman RH Korsmeyer SJ (2001) MLL and CREB bind cooperatively to the nuclear coactivator CREB-binding protein. Mol Cell Biol 21, 2249 2258.
    • (2001) Mol Cell Biol , vol.21 , pp. 2249-2258
    • Ernst, P.1    Wang, J.2    Huang, M.3    Goodman, R.H.4    Korsmeyer, S.J.5
  • 50
    • 0034282527 scopus 로고    scopus 로고
    • Chromatin-related properties of CBP fused to MLL generate a myelodysplastic-like syndrome that evolves into myeloid leukemia
    • Lavau C, Du C, Thirman M Zeleznik-Le N (2000) Chromatin-related properties of CBP fused to MLL generate a myelodysplastic-like syndrome that evolves into myeloid leukemia. EMBO J 19, 4655 4664.
    • (2000) EMBO J , vol.19 , pp. 4655-4664
    • Lavau, C.1    Du, C.2    Thirman, M.3    Zeleznik-Le, N.4
  • 53
    • 0037385212 scopus 로고    scopus 로고
    • Novel SWI/SNF chromatin-remodeling complexes contain a mixed-lineage leukemia chromosomal translocation partner
    • Nie Z, Yan Z, Chen EH, Sechi S, Ling C, Zhou S, Xue Y, Yang D, Murray D, Kanakubo E et al. (2003) Novel SWI/SNF chromatin-remodeling complexes contain a mixed-lineage leukemia chromosomal translocation partner. Mol Cell Biol 23, 2942 2952.
    • (2003) Mol Cell Biol , vol.23 , pp. 2942-2952
    • Nie, Z.1    Yan, Z.2    Chen, E.H.3    Sechi, S.4    Ling, C.5    Zhou, S.6    Xue, Y.7    Yang, D.8    Murray, D.9    Kanakubo, E.10
  • 56
    • 0038780088 scopus 로고    scopus 로고
    • MLL AT-hook sequence is strongly conserved in infant acute leukemia with or without MLL gene rearrangement
    • Macrini CM, Pombo-de-Oliveira MS, Ford AM Alves G (2003) MLL AT-hook sequence is strongly conserved in infant acute leukemia with or without MLL gene rearrangement. Leukemia 17, 1432 1433.
    • (2003) Leukemia , vol.17 , pp. 1432-1433
    • MacRini, C.M.1    Pombo-De-Oliveira, M.S.2    Ford, A.M.3    Alves, G.4
  • 57
    • 0031972784 scopus 로고    scopus 로고
    • The oncogenic capacity of HRX-ENL requires the transcriptional transactivation activity of ENL and the DNA binding motifs of HRX
    • Slany RK, Lavau C Cleary ML (1998) The oncogenic capacity of HRX-ENL requires the transcriptional transactivation activity of ENL and the DNA binding motifs of HRX. Mol Cell Biol 18, 122 129.
    • (1998) Mol Cell Biol , vol.18 , pp. 122-129
    • Slany, R.K.1    Lavau, C.2    Cleary, M.L.3
  • 58
    • 67650770689 scopus 로고    scopus 로고
    • The molecular biology of mixed lineage leukemia
    • Slany RK (2009) The molecular biology of mixed lineage leukemia. Haematologica 94, 984 993.
    • (2009) Haematologica , vol.94 , pp. 984-993
    • Slany, R.K.1
  • 59
    • 8644278033 scopus 로고    scopus 로고
    • Binding to nonmethylated CpG DNA is essential for target recognition, transactivation, and myeloid transformation by an MLL oncoprotein
    • Ayton PM, Chen EH Cleary ML (2004) Binding to nonmethylated CpG DNA is essential for target recognition, transactivation, and myeloid transformation by an MLL oncoprotein. Mol Cell Biol 24, 10470 10478.
    • (2004) Mol Cell Biol , vol.24 , pp. 10470-10478
    • Ayton, P.M.1    Chen, E.H.2    Cleary, M.L.3
  • 61
    • 45849088067 scopus 로고    scopus 로고
    • A MENage a Trois in leukemia
    • Roudaia L Speck NA (2008) A MENage a Trois in leukemia. Cancer Cell 14, 3 5.
    • (2008) Cancer Cell , vol.14 , pp. 3-5
    • Roudaia, L.1    Speck, N.A.2
  • 62
    • 77950501203 scopus 로고    scopus 로고
    • Mixed lineage leukemia: A structure-function perspective of the MLL1 protein
    • doi
    • Cosgrove MS Patel A (2010) Mixed lineage leukemia: a structure-function perspective of the MLL1 protein. FEBS J doi :.
    • (2010) FEBS J
    • Cosgrove, M.S.1    Patel, A.2
  • 64
    • 14744303696 scopus 로고    scopus 로고
    • Expanding functional diversity of the coactivators
    • Lonard DM O'Malley BW (2005) Expanding functional diversity of the coactivators. Trends Biochem Sci 30, 126 132.
    • (2005) Trends Biochem Sci , vol.30 , pp. 126-132
    • Lonard, D.M.1    O'Malley, B.W.2
  • 67
    • 66649100278 scopus 로고    scopus 로고
    • Crucial roles for interactions between MLL3/4 and INI1 in nuclear receptor transactivation
    • Lee S, Kim DH, Goo YH, Lee YC, Lee SK Lee JW (2009) Crucial roles for interactions between MLL3/4 and INI1 in nuclear receptor transactivation. Mol Endocrinol 23, 610 619.
    • (2009) Mol Endocrinol , vol.23 , pp. 610-619
    • Lee, S.1    Kim, D.H.2    Goo, Y.H.3    Lee, Y.C.4    Lee, S.K.5    Lee, J.W.6
  • 68
    • 34548252291 scopus 로고    scopus 로고
    • Nuclear receptor coregulators: Judges, juries, and executioners of cellular regulation
    • Lonard DM O'Malley BW (2007) Nuclear receptor coregulators: judges, juries, and executioners of cellular regulation. Mol Cell 27, 691 700.
    • (2007) Mol Cell , vol.27 , pp. 691-700
    • Lonard, D.M.1    O'Malley, B.W.2
  • 69
    • 47749116006 scopus 로고    scopus 로고
    • Nuclear receptors and coregulators in inflammation and cancer
    • Lee JS, Kim KI Baek SH (2008) Nuclear receptors and coregulators in inflammation and cancer. Cancer Lett 267, 189 196.
    • (2008) Cancer Lett , vol.267 , pp. 189-196
    • Lee, J.S.1    Kim, K.I.2    Baek, S.H.3
  • 70
    • 33744903415 scopus 로고    scopus 로고
    • Identification of the MLL2 complex as a coactivator for estrogen receptor alpha
    • Mo R, Rao SM Zhu YJ (2006) Identification of the MLL2 complex as a coactivator for estrogen receptor alpha. J Biol Chem 281, 15714 15720.
    • (2006) J Biol Chem , vol.281 , pp. 15714-15720
    • Mo, R.1    Rao, S.M.2    Zhu, Y.J.3
  • 71
    • 66849100568 scopus 로고    scopus 로고
    • Multiple endocrine neoplasia type 1: A chromatin writer's block
    • Dreijerink KM, Lips CJ Timmers HT (2009) Multiple endocrine neoplasia type 1: a chromatin writer's block. J Intern Med 266, 53 59.
    • (2009) J Intern Med , vol.266 , pp. 53-59
    • Dreijerink, K.M.1    Lips, C.J.2    Timmers, H.T.3
  • 72
    • 66649120472 scopus 로고    scopus 로고
    • A tumor suppressive coactivator complex of p53 containing ASC-2 and histone H3-lysine-4 methyltransferase MLL3 or its paralogue MLL4
    • Lee J, Kim DH, Lee S, Yang QH, Lee DK, Lee SK, Roeder RG Lee JW (2009) A tumor suppressive coactivator complex of p53 containing ASC-2 and histone H3-lysine-4 methyltransferase MLL3 or its paralogue MLL4. Proc Natl Acad Sci USA 106, 8513 8518.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 8513-8518
    • Lee, J.1    Kim, D.H.2    Lee, S.3    Yang, Q.H.4    Lee, D.K.5    Lee, S.K.6    Roeder, R.G.7    Lee, J.W.8
  • 73
    • 58049206724 scopus 로고    scopus 로고
    • Targeted inactivation of MLL3 histone H3-Lys-4 methyltransferase activity in the mouse reveals vital roles for MLL3 in adipogenesis
    • Lee J, Saha PK, Yang QH, Lee S, Park JY, Suh Y, Lee SK, Chan L, Roeder RG Lee JW (2008) Targeted inactivation of MLL3 histone H3-Lys-4 methyltransferase activity in the mouse reveals vital roles for MLL3 in adipogenesis. Proc Natl Acad Sci USA 105, 19229 19234.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 19229-19234
    • Lee, J.1    Saha, P.K.2    Yang, Q.H.3    Lee, S.4    Park, J.Y.5    Suh, Y.6    Lee, S.K.7    Chan, L.8    Roeder, R.G.9    Lee, J.W.10
  • 77
    • 33847068858 scopus 로고    scopus 로고
    • Posterior Hox gene expression and differential androgen regulation in the developing and adult rat prostate lobes
    • Huang L, Pu Y, Hepps D, Danielpour D Prins GS (2007) Posterior Hox gene expression and differential androgen regulation in the developing and adult rat prostate lobes. Endocrinology 148, 1235 1245.
    • (2007) Endocrinology , vol.148 , pp. 1235-1245
    • Huang, L.1    Pu, Y.2    Hepps, D.3    Danielpour, D.4    Prins, G.S.5
  • 79
    • 0033304625 scopus 로고    scopus 로고
    • Hoxa-10 regulates uterine stromal cell responsiveness to progesterone during implantation and decidualization in the mouse
    • Lim H, Ma L, Ma WG, Maas RL Dey SK (1999) Hoxa-10 regulates uterine stromal cell responsiveness to progesterone during implantation and decidualization in the mouse. Mol Endocrinol 13, 1005 1017.
    • (1999) Mol Endocrinol , vol.13 , pp. 1005-1017
    • Lim, H.1    Ma, L.2    Ma, W.G.3    Maas, R.L.4    Dey, S.K.5
  • 80
    • 0032523915 scopus 로고    scopus 로고
    • Abdominal B (AbdB) Hoxa genes: Regulation in adult uterus by estrogen and progesterone and repression in Mullerian duct by the synthetic estrogen diethylstilbestrol (DES)
    • Ma L, Benson GV, Lim H, Dey SK Maas RL (1998) Abdominal B (AbdB) Hoxa genes: regulation in adult uterus by estrogen and progesterone and repression in Mullerian duct by the synthetic estrogen diethylstilbestrol (DES). Dev Biol 197, 141 154.
    • (1998) Dev Biol , vol.197 , pp. 141-154
    • Ma, L.1    Benson, G.V.2    Lim, H.3    Dey, S.K.4    Maas, R.L.5
  • 81
    • 0038074197 scopus 로고    scopus 로고
    • Hoxb13 is required for normal differentiation and secretory function of the ventral prostate
    • Economides KD Capecchi MR (2003) Hoxb13 is required for normal differentiation and secretory function of the ventral prostate. Development 130, 2061 2069.
    • (2003) Development , vol.130 , pp. 2061-2069
    • Economides, K.D.1    Capecchi, M.R.2
  • 82
    • 0033775120 scopus 로고    scopus 로고
    • Differential mammary morphogenesis along the anteroposterior axis in Hoxc6 gene targeted mice
    • Garcia-Gasca A Spyropoulos DD (2000) Differential mammary morphogenesis along the anteroposterior axis in Hoxc6 gene targeted mice. Dev Dyn 219, 261 276.
    • (2000) Dev Dyn , vol.219 , pp. 261-276
    • Garcia-Gasca, A.1    Spyropoulos, D.D.2
  • 83
    • 0034094901 scopus 로고    scopus 로고
    • In utero diethylstilbestrol (DES) exposure alters Hox gene expression in the developing Mullerian system
    • Block K, Kardana A, Igarashi P Taylor HS (2000) In utero diethylstilbestrol (DES) exposure alters Hox gene expression in the developing Mullerian system. FASEB J 14, 1101 1108.
    • (2000) FASEB J , vol.14 , pp. 1101-1108
    • Block, K.1    Kardana, A.2    Igarashi, P.3    Taylor, H.S.4
  • 84
    • 71949085489 scopus 로고    scopus 로고
    • MLL histone methylases in estrogen-dependent regulation of HOXC13
    • Ansari KI, Kasiri S, Hussain I Mandal SS (2009) MLL histone methylases in estrogen-dependent regulation of HOXC13. FEBS J 276, 7400 7411.
    • (2009) FEBS J , vol.276 , pp. 7400-7411
    • Ansari, K.I.1    Kasiri, S.2    Hussain, I.3    Mandal, S.S.4
  • 87
    • 2342465953 scopus 로고    scopus 로고
    • Recent highlights of RNA-polymerase-II-mediated transcription
    • Sims RJ III., Mandal SS Reinberg D (2004) Recent highlights of RNA-polymerase-II-mediated transcription. Curr Opin Cell Biol 16, 263 271.
    • (2004) Curr Opin Cell Biol , vol.16 , pp. 263-271
    • Sims, III.R.J.1    Mandal, S.S.2    Reinberg, D.3
  • 88
    • 29644433964 scopus 로고    scopus 로고
    • Human but not yeast CHD1 binds directly and selectively to histone H3 methylated at lysine 4 via its tandem chromodomains
    • Sims RJ III., Chen CF, Santos-Rosa H, Kouzarides T, Patel SS Reinberg D (2005) Human but not yeast CHD1 binds directly and selectively to histone H3 methylated at lysine 4 via its tandem chromodomains. J Biol Chem 280, 41789 41792.
    • (2005) J Biol Chem , vol.280 , pp. 41789-41792
    • Sims, III.R.J.1    Chen, C.F.2    Santos-Rosa, H.3    Kouzarides, T.4    Patel, S.S.5    Reinberg, D.6
  • 91
    • 13244253805 scopus 로고    scopus 로고
    • Steroid hormone receptor coactivation and alternative RNA splicing by U2AF65-related proteins CAPERalpha and CAPERbeta
    • Dowhan DH, Hong EP, Auboeuf D, Dennis AP, Wilson MM, Berget SM O'Malley BW (2005) Steroid hormone receptor coactivation and alternative RNA splicing by U2AF65-related proteins CAPERalpha and CAPERbeta. Mol Cell 17, 429 439.
    • (2005) Mol Cell , vol.17 , pp. 429-439
    • Dowhan, D.H.1    Hong, E.P.2    Auboeuf, D.3    Dennis, A.P.4    Wilson, M.M.5    Berget, S.M.6    O'Malley, B.W.7
  • 92
    • 20744451863 scopus 로고    scopus 로고
    • A subset of nuclear receptor coregulators act as coupling proteins during synthesis and maturation of RNA transcripts
    • Auboeuf D, Dowhan DH, Dutertre M, Martin N, Berget SM O'Malley BW (2005) A subset of nuclear receptor coregulators act as coupling proteins during synthesis and maturation of RNA transcripts. Mol Cell Biol 25, 5307 5316.
    • (2005) Mol Cell Biol , vol.25 , pp. 5307-5316
    • Auboeuf, D.1    Dowhan, D.H.2    Dutertre, M.3    Martin, N.4    Berget, S.M.5    O'Malley, B.W.6


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