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Volumn 5, Issue 4, 2006, Pages 360-362

The mechanism of hematopoietic progenitor cell immortalization by MLL-ENL

Author keywords

Conditional expression; HOX; Leukemia; MLL ENL; Myeloid progenitor

Indexed keywords

CYTOKINE; ELEVEN NINETEEN LEUKEMIA PROTEIN; GRANULOCYTE COLONY STIMULATING FACTOR; HYBRID PROTEIN; MIXED LINEAGE LEUKEMIA PROTEIN; PROTEIN; UNCLASSIFIED DRUG;

EID: 33645214191     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.5.4.2464     Document Type: Short Survey
Times cited : (6)

References (38)
  • 1
    • 0034235115 scopus 로고    scopus 로고
    • Biological and therapeutic aspects of infant leukemia
    • Biondi A, Cimino G, Pieters R, Pui CH. Biological and therapeutic aspects of infant leukemia. Blood 2000; 96:24-33.
    • (2000) Blood , vol.96 , pp. 24-33
    • Biondi, A.1    Cimino, G.2    Pieters, R.3    Pui, C.H.4
  • 2
    • 0026936328 scopus 로고
    • A trithorax-like gene is interrupted by chromosome 11q23 translocations in acute leukaemias
    • Djabali M, Selleri L, Parry P, Bower M, Young BD, Evans GA. A trithorax-like gene is interrupted by chromosome 11q23 translocations in acute leukaemias. Nat Genet 1992; 2:113-8.
    • (1992) Nat Genet , vol.2 , pp. 113-118
    • Djabali, M.1    Selleri, L.2    Parry, P.3    Bower, M.4    Young, B.D.5    Evans, G.A.6
  • 3
    • 0026496887 scopus 로고
    • The t(4;11) chromosome translocation of human acute leukemias fuses the ALL-1 gene, related to Drosophila trithorax, to the AF-4 gene
    • Gu Y, Nakamura T, Alder H, Prasad R, Canaani O, Cimino G, Croce CM, Canaani E. The t(4;11) chromosome translocation of human acute leukemias fuses the ALL-1 gene, related to Drosophila trithorax, to the AF-4 gene. Cell 1992; 71:701-8.
    • (1992) Cell , vol.71 , pp. 701-708
    • Gu, Y.1    Nakamura, T.2    Alder, H.3    Prasad, R.4    Canaani, O.5    Cimino, G.6    Croce, C.M.7    Canaani, E.8
  • 4
    • 0026454451 scopus 로고
    • Involvement of a homolog of Drosophila trithorax by 11q23 chromosomal translocations in acute leukemias
    • Tkachuk DC, Kohler S, Cleary ML. Involvement of a homolog of Drosophila trithorax by 11q23 chromosomal translocations in acute leukemias. Cell 1992; 71:691-700.
    • (1992) Cell , vol.71 , pp. 691-700
    • Tkachuk, D.C.1    Kohler, S.2    Cleary, M.L.3
  • 5
    • 0027536183 scopus 로고
    • Trithorax regulates multiple homeotic genes in the bithorax and Antennapedia complexes and exerts different tissue-specific, parasegment-specific and promoter-specific effects on each
    • Breen TR, Harte PJ. Trithorax regulates multiple homeotic genes in the bithorax and Antennapedia complexes and exerts different tissue-specific, parasegment-specific and promoter-specific effects on each. Development 1993; 117:119-34.
    • (1993) Development , vol.117 , pp. 119-134
    • Breen, T.R.1    Harte, P.J.2
  • 6
    • 0029954818 scopus 로고    scopus 로고
    • The role of HOX homeobox genes in normal and leukemic hematopoiesis
    • Lawrence HJ, Sauvageau G, Humphries RK, Largman C. The role of HOX homeobox genes in normal and leukemic hematopoiesis. Stem Cells 1996; 14:281-91.
    • (1996) Stem Cells , vol.14 , pp. 281-291
    • Lawrence, H.J.1    Sauvageau, G.2    Humphries, R.K.3    Largman, C.4
  • 8
  • 9
    • 0030954681 scopus 로고    scopus 로고
    • Defects in yolk sac hematopoiesis in Mll-null embryos
    • Hess JL, Yu BD, Li B, Hanson R, Korsmeyer SJ. Defects in yolk sac hematopoiesis in Mll-null embryos. Blood 1997; 90:1799-806.
    • (1997) Blood , vol.90 , pp. 1799-1806
    • Hess, J.L.1    Yu, B.D.2    Li, B.3    Hanson, R.4    Korsmeyer, S.J.5
  • 10
    • 0032126677 scopus 로고    scopus 로고
    • Growth disturbance in fetal liver hematopoiesis of Mll-mutant mice
    • Yagi H, Deguchi K, Aono A, Tani Y, Kishimoto T, Komori T. Growth disturbance in fetal liver hematopoiesis of Mll-mutant mice. Blood 1998; 92:108-17.
    • (1998) Blood , vol.92 , pp. 108-117
    • Yagi, H.1    Deguchi, K.2    Aono, A.3    Tani, Y.4    Kishimoto, T.5    Komori, T.6
  • 11
    • 0032168459 scopus 로고    scopus 로고
    • MLL, a mammalian trithorax-group gene, functions as a transcriptional maintenance factor in morphogenesis
    • USA
    • Yu BD, Hanson RD, Hess JL, Horning SE, Korsmeyer SJ. MLL, a mammalian trithorax-group gene, functions as a transcriptional maintenance factor in morphogenesis. Proc Natl Acad Sci USA 1998; 95:10632-6.
    • (1998) Proc Natl Acad Sci , vol.95 , pp. 10632-10636
    • Yu, B.D.1    Hanson, R.D.2    Hess, J.L.3    Horning, S.E.4    Korsmeyer, S.J.5
  • 13
    • 0037071408 scopus 로고    scopus 로고
    • Transcription factor fusions in acute leukemia: Variations on a theme
    • Scandura JM, Boccuni P, Cammenga J, Nimer SD. Transcription factor fusions in acute leukemia: Variations on a theme. Oncogene 2002; 21:3422-44.
    • (2002) Oncogene , vol.21 , pp. 3422-3444
    • Scandura, J.M.1    Boccuni, P.2    Cammenga, J.3    Nimer, S.D.4
  • 14
    • 0030791974 scopus 로고    scopus 로고
    • Immortalization and leukemic transformation of a myelomonocytic precursor by retrovirally transduced HRX-ENL
    • Lavau C, Szilvassy SJ, Slany R, Cleary ML. Immortalization and leukemic transformation of a myelomonocytic precursor by retrovirally transduced HRX-ENL. Embo J 1997; 16:4226-37.
    • (1997) Embo J , vol.16 , pp. 4226-4237
    • Lavau, C.1    Szilvassy, S.J.2    Slany, R.3    Cleary, M.L.4
  • 15
    • 0346100567 scopus 로고    scopus 로고
    • Similar MLL-associated leukemias arising from self-renewing stem cells and short-lived myeloid progenitors
    • Cozzio A, Passegue E, Ayton PM, Karsunky H, Cleary ML, Weissman IL. Similar MLL-associated leukemias arising from self-renewing stem cells and short-lived myeloid progenitors. Genes Dev 2003; 17:3029-35.
    • (2003) Genes Dev , vol.17 , pp. 3029-3035
    • Cozzio, A.1    Passegue, E.2    Ayton, P.M.3    Karsunky, H.4    Cleary, M.L.5    Weissman, I.L.6
  • 16
    • 0037456994 scopus 로고    scopus 로고
    • The oncoprotein MLL-ENL disturbs hematopoietic lineage determination and transforms a biphenotypic lymphoid/myeloid cell
    • Zeisig BB, Garcia-Cuellar MP, Winkler TH, Slany RK. The oncoprotein MLL-ENL disturbs hematopoietic lineage determination and transforms a biphenotypic lymphoid/myeloid cell. Oncogene 2003; 22:1629-37.
    • (2003) Oncogene , vol.22 , pp. 1629-1637
    • Zeisig, B.B.1    Garcia-Cuellar, M.P.2    Winkler, T.H.3    Slany, R.K.4
  • 17
    • 0345582392 scopus 로고    scopus 로고
    • Engineering de novo reciprocal chromosomal translocations associated with Mll to replicate primary events of human cancer
    • Forster A, Pannell R, Drynan LF, McCormack M, Collins EC, Daser A, Rabbitts TH. Engineering de novo reciprocal chromosomal translocations associated with Mll to replicate primary events of human cancer. Cancer Cell 2003; 3:449-58.
    • (2003) Cancer Cell , vol.3 , pp. 449-458
    • Forster, A.1    Pannell, R.2    Drynan, L.F.3    McCormack, M.4    Collins, E.C.5    Daser, A.6    Rabbitts, T.H.7
  • 19
    • 0037732933 scopus 로고    scopus 로고
    • Genome-wide analysis of acute myeloid leukemia with normal karyotype reveals a unique pattern of homeobox gene expression distinct from those with translocation-mediated fusion events
    • Debernardi S, Lillington DM, Chaplin T, Tomlinson S, Amess J, Rohatiner A, Lister TA, Young BD. Genome-wide analysis of acute myeloid leukemia with normal karyotype reveals a unique pattern of homeobox gene expression distinct from those with translocation-mediated fusion events. Genes Chromosomes Cancer 2003; 37:149-58.
    • (2003) Genes Chromosomes Cancer , vol.37 , pp. 149-158
    • Debernardi, S.1    Lillington, D.M.2    Chaplin, T.3    Tomlinson, S.4    Amess, J.5    Rohatiner, A.6    Lister, T.A.7    Young, B.D.8
  • 21
    • 9244257908 scopus 로고    scopus 로고
    • An Mll-dependent Hox program drives hematopoietic progenitor expansion
    • Ernst P, Mabon M, Davidson AJ, Zon LI, Korsmeyer SJ. An Mll-dependent Hox program drives hematopoietic progenitor expansion. Curr Biol 2004; 14:2063-9.
    • (2004) Curr Biol , vol.14 , pp. 2063-2069
    • Ernst, P.1    Mabon, M.2    Davidson, A.J.3    Zon, L.I.4    Korsmeyer, S.J.5
  • 23
    • 0032126633 scopus 로고    scopus 로고
    • Hoxa9 transforms primary bone marrow cells through specific collaboration with Meis1a but not Pbx1b
    • Kroon E, Krosl J, Thorsteinsdottir U, Baban S, Buchberg AM, Sauvageau G. Hoxa9 transforms primary bone marrow cells through specific collaboration with Meis1a but not Pbx1b. Embo J 1998; 17:3714-25.
    • (1998) Embo J , vol.17 , pp. 3714-3725
    • Kroon, E.1    Krosl, J.2    Thorsteinsdottir, U.3    Baban, S.4    Buchberg, A.M.5    Sauvageau, G.6
  • 24
    • 4644220954 scopus 로고    scopus 로고
    • MLL: A histone methyltransferase disrupted in leukemia
    • Hess JL. MLL: A histone methyltransferase disrupted in leukemia. Trends Mol Med 2004; 10:500-7.
    • (2004) Trends Mol Med , vol.10 , pp. 500-507
    • Hess, J.L.1
  • 27
    • 0041370095 scopus 로고    scopus 로고
    • Transformation of myeloid progenitors by MLL oncoproteins is dependent on Hoxa7 and Hoxa9
    • Ayton PM, Cleary ML. Transformation of myeloid progenitors by MLL oncoproteins is dependent on Hoxa7 and Hoxa9. Genes Dev 2003; 17:2298-307.
    • (2003) Genes Dev , vol.17 , pp. 2298-2307
    • Ayton, P.M.1    Cleary, M.L.2
  • 28
    • 0042885909 scopus 로고    scopus 로고
    • Dimerization contributes to oncogenic activation of MLL chimeras in acute leukemias
    • So CW, Lin M, Ayton PM, Chen EH, Cleary ML. Dimerization contributes to oncogenic activation of MLL chimeras in acute leukemias. Cancer Cell 2003; 4:99-110.
    • (2003) Cancer Cell , vol.4 , pp. 99-110
    • So, C.W.1    Lin, M.2    Ayton, P.M.3    Chen, E.H.4    Cleary, M.L.5
  • 32
    • 0036142691 scopus 로고    scopus 로고
    • Differential expression of Hox, Meis1, and Pbx1 genes in primitive cells throughout murine hematopoietic ontogeny
    • Pineault N, Helgason CD, Lawrence HJ, Humphries RK. Differential expression of Hox, Meis1, and Pbx1 genes in primitive cells throughout murine hematopoietic ontogeny. Exp Hematol 2002; 30:49-57.
    • (2002) Exp Hematol , vol.30 , pp. 49-57
    • Pineault, N.1    Helgason, C.D.2    Lawrence, H.J.3    Humphries, R.K.4
  • 33
    • 0035419401 scopus 로고    scopus 로고
    • MLL-ENL causes a reversible and myc-dependent block of myelomonocytic cell differentiation
    • Schreiner S, Birke M, Garcia-Cuellar MP, Zilles O, Greil J, Slany RK. MLL-ENL causes a reversible and myc-dependent block of myelomonocytic cell differentiation. Cancer Res 2001; 61:6480-6.
    • (2001) Cancer Res , vol.61 , pp. 6480-6486
    • Schreiner, S.1    Birke, M.2    Garcia-Cuellar, M.P.3    Zilles, O.4    Greil, J.5    Slany, R.K.6
  • 35
    • 0034000574 scopus 로고    scopus 로고
    • Hoxa9 immortalizes a granulocyte-macrophage colony-stimulating factor-dependent promyelocyte capable of biphenotypic differentiation to neutrophils or macrophages, independent of enforced meis expression
    • Calvo KR, Sykes DB, Pasillas M, Kamps MP. Hoxa9 immortalizes a granulocyte-macrophage colony-stimulating factor-dependent promyelocyte capable of biphenotypic differentiation to neutrophils or macrophages, independent of enforced meis expression. Mol Cell Biol 2000; 20:3274-85.
    • (2000) Mol Cell Biol , vol.20 , pp. 3274-3285
    • Calvo, K.R.1    Sykes, D.B.2    Pasillas, M.3    Kamps, M.P.4
  • 36
    • 0035818522 scopus 로고    scopus 로고
    • Meis1a suppresses differentiation by G-CSF and promotes proliferation by SCF: Potential mechanisms of cooperativity with Hoxa9 in myeloid leukemia
    • USA
    • Calvo KR, Knoepfler PS, Sykes DB, Pasillas MP, Kamps MP. Meis1a suppresses differentiation by G-CSF and promotes proliferation by SCF: Potential mechanisms of cooperativity with Hoxa9 in myeloid leukemia. Proc Natl Acad Sci USA 2001; 98:13120-5.
    • (2001) Proc Natl Acad Sci , vol.98 , pp. 13120-13125
    • Calvo, K.R.1    Knoepfler, P.S.2    Sykes, D.B.3    Pasillas, M.P.4    Kamps, M.P.5
  • 37
    • 22044434682 scopus 로고    scopus 로고
    • Meis1 programs transcription of FLT3 and cancer stem cell character, using a mechanism that requires interaction with Pbx and a novel function of the Meis1 C-terminus
    • Wang GG, Pasillas MP, Kamps MP. Meis1 programs transcription of FLT3 and cancer stem cell character, using a mechanism that requires interaction with Pbx and a novel function of the Meis1 C-terminus. Blood 2005; 106:254-64.
    • (2005) Blood , vol.106 , pp. 254-264
    • Wang, G.G.1    Pasillas, M.P.2    Kamps, M.P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.