-
1
-
-
34248159338
-
Protein stress and stress proteins: Implications in aging and disease
-
Söti, C.; Csermely, P. Protein stress and stress proteins: implications in aging and disease. J. Biosci., 2007, 328(3), 511-515.
-
(2007)
J. Biosci
, vol.328
, Issue.3
, pp. 511-515
-
-
Söti, C.1
Csermely, P.2
-
2
-
-
34447498553
-
Stress-induced rearrangements of cellular networks: Consequences for protection and drug design
-
Szalay, M.S.; Kovács, I.A.; Korcsmáros, T.; Böde, C.; Csermely, P. Stress-induced rearrangements of cellular networks: Consequences for protection and drug design FEBS Lett., 2007, 581(19), 3675-3680.
-
(2007)
FEBS Lett
, vol.581
, Issue.19
, pp. 3675-3680
-
-
Szalay, M.S.1
Kovács, I.A.2
Korcsmáros, T.3
Böde, C.4
Csermely, P.5
-
3
-
-
0036198149
-
Multiple stressors in Caenorhabditis elegans induce stress hormesis and extended longevity
-
Cypser, J.R.; Johnson, T.E. Multiple stressors in Caenorhabditis elegans induce stress hormesis and extended longevity. Gerontol. A Biol. Sci. Med. Sci., 2002, 57(3), B109-114.
-
(2002)
Gerontol. A Biol. Sci. Med. Sci
, vol.57
, Issue.3
-
-
Cypser, J.R.1
Johnson, T.E.2
-
4
-
-
33745469011
-
The failure of dose-response models to predict low dose effects: A major challenge for biomedical, toxicological and aging research
-
Calabrese, E.J. The failure of dose-response models to predict low dose effects: a major challenge for biomedical, toxicological and aging research. Biogerontology, 2006, 7(2), 119-122.
-
(2006)
Biogerontology
, vol.7
, Issue.2
, pp. 119-122
-
-
Calabrese, E.J.1
-
5
-
-
63049110712
-
Psychological and metabolic stress: A recipe for accelerated cellular aging?
-
Epel, E.S. Psychological and metabolic stress: a recipe for accelerated cellular aging? Hormones, 2009, 8(1), 7-22.
-
(2009)
Hormones
, vol.8
, Issue.1
, pp. 7-22
-
-
Epel, E.S.1
-
6
-
-
64949099855
-
Protein homeostasis and aging: Taking care of proteins from the cradle to the grave
-
Morimoto, R.I.; Cuervo, A.M. Protein homeostasis and aging: taking care of proteins from the cradle to the grave. J. Gerontol. A Biol. Sci. Med. Sci., 2009, 63A(2), 167-170.
-
(2009)
J. Gerontol. A Biol. Sci. Med. Sci
, vol.63 A
, Issue.2
, pp. 167-170
-
-
Morimoto, R.I.1
Cuervo, A.M.2
-
7
-
-
44849094781
-
Proteotoxic stress and inducible chaperone networks in neurodegenerative disease and aging
-
Morimoto, R.I. Proteotoxic stress and inducible chaperone networks in neurodegenerative disease and aging. Genes Dev., 2008, 22(11), 1427-1438.
-
(2008)
Genes Dev
, vol.22
, Issue.11
, pp. 1427-1438
-
-
Morimoto, R.I.1
-
8
-
-
15044351289
-
Molecular chaperones as regulatory elements of cellular networks
-
Söti, C.; Pal, C.; Papp, B.; Csermely, P. Molecular chaperones as regulatory elements of cellular networks. Curr. Opin. Cell Biol., 2005, 17(2), 210-215.
-
(2005)
Curr. Opin. Cell Biol
, vol.17
, Issue.2
, pp. 210-215
-
-
Söti, C.1
Pal, C.2
Papp, B.3
Csermely, P.4
-
9
-
-
33845564533
-
Aging cellular networks: Chaperones as major participants
-
Söti, C.; Csermely, P. Aging cellular networks: chaperones as major participants. Exp. Gerontol., 2007, 42(1-2), 113-119.
-
(2007)
Exp. Gerontol
, vol.42
, Issue.1-2
, pp. 113-119
-
-
Söti, C.1
Csermely, P.2
-
10
-
-
42949165604
-
Chaperones as integrators of cellular networks: Changes of cellular integrity in stress and diseases
-
Palotai, R.; Szalay, M.S.; Csermely, P. Chaperones as integrators of cellular networks: changes of cellular integrity in stress and diseases. IUBMB Life, 2008, 60(1), 10-18.
-
(2008)
IUBMB Life
, vol.60
, Issue.1
, pp. 10-18
-
-
Palotai, R.1
Szalay, M.S.2
Csermely, P.3
-
11
-
-
0037040541
-
Molecular chaperones in the cytosol: From nascent chain to folded protein
-
Hartl, F.U.; Hayer-Hartl, M. Molecular chaperones in the cytosol: from nascent chain to folded protein. Science, 2002, 295(5561), 1852-1858.
-
(2002)
Science
, vol.295
, Issue.5561
, pp. 1852-1858
-
-
Hartl, F.U.1
Hayer-Hartl, M.2
-
12
-
-
11444271010
-
Chaperone-assisted folding of newly synthesized proteins in the cytosol
-
Deuerling, E.; Bukau, B. Chaperone-assisted folding of newly synthesized proteins in the cytosol. Crit. Rev. Biochem. Mol. Biol., 2004, 39(5-6), 261-277.
-
(2004)
Crit. Rev. Biochem. Mol. Biol
, vol.39
, Issue.5-6
, pp. 261-277
-
-
Deuerling, E.1
Bukau, B.2
-
13
-
-
33646127577
-
Molecular chaperones and protein quality control
-
Bukau, B.; Weissman, J.; Horwich, A. Molecular chaperones and protein quality control. Cell, 2006, 125(3), 443-451.
-
(2006)
Cell
, vol.125
, Issue.3
, pp. 443-451
-
-
Bukau, B.1
Weissman, J.2
Horwich, A.3
-
14
-
-
34250899722
-
Signal integration in the endoplasmic reticulum unfolded protein response
-
Ron, D.; Walter, P. Signal integration in the endoplasmic reticulum unfolded protein response. Nat. Rev. Mol. Cell Biol., 2007, 8(7), 519-529.
-
(2007)
Nat. Rev. Mol. Cell Biol
, vol.8
, Issue.7
, pp. 519-529
-
-
Ron, D.1
Walter, P.2
-
15
-
-
0032535245
-
Regulation of the heat shock transcriptional response: Cross talk between a family of heat shock factors, molecular chaperones, and negative regulators
-
Morimoto, R.I. Regulation of the heat shock transcriptional response: cross talk between a family of heat shock factors, molecular chaperones, and negative regulators. Genes. Dev., 1998, 12(24), 3788-3796.
-
(1998)
Genes. Dev
, vol.12
, Issue.24
, pp. 3788-3796
-
-
Morimoto, R.I.1
-
16
-
-
33645324024
-
RNA-mediated response to heat shock in mammalian cells
-
Shamovsky, I.; Ivannikov, M.; Kandel, E.S.; Gershon, D.; Nudler, E. RNA-mediated response to heat shock in mammalian cells. Nature, 2006, 440(7083), 556-560.
-
(2006)
Nature
, vol.440
, Issue.7083
, pp. 556-560
-
-
Shamovsky, I.1
Ivannikov, M.2
Kandel, E.S.3
Gershon, D.4
Nudler, E.5
-
17
-
-
43249125196
-
New insights into the mechanism of heat shock response activation
-
Shamovsky, I.; Nudler, E. New insights into the mechanism of heat shock response activation. Cell. Mol. Life Sci., 2008, 65(6), 855-861.
-
(2008)
Cell. Mol. Life Sci
, vol.65
, Issue.6
, pp. 855-861
-
-
Shamovsky, I.1
Nudler, E.2
-
18
-
-
17744372861
-
Roles of the heat shock transcription factors in regulation of the heat shock response and beyond
-
Pirkkala, L.; Nykänen, P.; Sistonen, L. Roles of the heat shock transcription factors in regulation of the heat shock response and beyond. FASEB J., 2001, 15(7), 1118-1131.
-
(2001)
FASEB J
, vol.15
, Issue.7
, pp. 1118-1131
-
-
Pirkkala, L.1
Nykänen, P.2
Sistonen, L.3
-
19
-
-
0027461364
-
Activation of heat shock gene transcription by heat shock factor 1 involves oligomerization, acquisition of DNA-binding activity, and nuclear localization and can occur in the absence of stress
-
Sarge, K.D.; Murphy, S.P.; Morimoto, R.I. Activation of heat shock gene transcription by heat shock factor 1 involves oligomerization, acquisition of DNA-binding activity, and nuclear localization and can occur in the absence of stress. Mol. Cell. Biol., 1993, 13(3), 1392-1407.
-
(1993)
Mol. Cell. Biol
, vol.13
, Issue.3
, pp. 1392-1407
-
-
Sarge, K.D.1
Murphy, S.P.2
Morimoto, R.I.3
-
20
-
-
0033536006
-
Rapid and reversible relocalization of heat shock factor 1 within seconds to nuclear stress granules
-
Jolly, C.; Usson, Y.; Morimoto, R.I. Rapid and reversible relocalization of heat shock factor 1 within seconds to nuclear stress granules. Proc. Natl. Acad. Sci. USA, 1999, 96(12), 6769-6774.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, Issue.12
, pp. 6769-6774
-
-
Jolly, C.1
Usson, Y.2
Morimoto, R.I.3
-
21
-
-
0033015180
-
A novel hnRNP protein (HAP/SAF-B) enters a subset of hnRNP complexes and relocates in nuclear granules in response to heat shock
-
Weighardt, F.; Cobianchi, F.; Cartegni, L.; Chiodi, I.; Villa, A.; Riva, S.; Biamonti, G. A novel hnRNP protein (HAP/SAF-B) enters a subset of hnRNP complexes and relocates in nuclear granules in response to heat shock. J. Cell. Sci., 1999, 112 (Pt 10), 1465-1476.
-
(1999)
J. Cell. Sci
, vol.112
, Issue.PART 10
, pp. 1465-1476
-
-
Weighardt, F.1
Cobianchi, F.2
Cartegni, L.3
Chiodi, I.4
Villa, A.5
Riva, S.6
Biamonti, G.7
-
22
-
-
0035192625
-
Stress-induced nuclear bodies are sites of accumulation of pre-mRNA processing factors
-
Denegri, M.; Chiodi, I.; Corioni, M.; Cobianchi, F.; Riva, S.; Biamonti, G. Stress-induced nuclear bodies are sites of accumulation of pre-mRNA processing factors. Mol. Biol. Cell., 2001, 12(11), 3502-3514.
-
(2001)
Mol. Biol. Cell
, vol.12
, Issue.11
, pp. 3502-3514
-
-
Denegri, M.1
Chiodi, I.2
Corioni, M.3
Cobianchi, F.4
Riva, S.5
Biamonti, G.6
-
23
-
-
0036021375
-
Genetic analysis of tissue aging in Caenorhabditis elegans: A role for heat-shock factor and bacterial proliferation
-
Garigan, D.; Hsu, A.L.; Fraser, A.G.; Kamath, R.S.; Ahringer, J.; Kenyon, C. Genetic analysis of tissue aging in Caenorhabditis elegans: a role for heat-shock factor and bacterial proliferation. Genetics, 2002, 161(3), 1101-1112.
-
(2002)
Genetics
, vol.161
, Issue.3
, pp. 1101-1112
-
-
Garigan, D.1
Hsu, A.L.2
Fraser, A.G.3
Kamath, R.S.4
Ahringer, J.5
Kenyon, C.6
-
24
-
-
0038701745
-
Regulation of aging and age-related disease by DAF-16 and heat-shock factor
-
Hsu, A.L.; Murphy, C.T.; Kenyon, C. Regulation of aging and age-related disease by DAF-16 and heat-shock factor. Science, 2003, 300(5622), 1142-1145.
-
(2003)
Science
, vol.300
, Issue.5622
, pp. 1142-1145
-
-
Hsu, A.L.1
Murphy, C.T.2
Kenyon, C.3
-
25
-
-
0033229880
-
HSF1 is required for extraembryonic development, postnatal growth and protection during inflammatory responses in mice
-
Xiao, X.; Zuo, X.; Davis, A.A.; McMillan, D.R.; Curry, B.B.; Richardson, J.A.; Benjamin, I.J. HSF1 is required for extraembryonic development, postnatal growth and protection during inflammatory responses in mice. EMBO J., 1999, 18(21), 5943-5952.
-
(1999)
EMBO J
, vol.18
, Issue.21
, pp. 5943-5952
-
-
Xiao, X.1
Zuo, X.2
Davis, A.A.3
McMillan, D.R.4
Curry, B.B.5
Richardson, J.A.6
Benjamin, I.J.7
-
26
-
-
23044445756
-
A stress-sensitive reporter predicts longevity in isogenic populations of Caenorhabditis elegans
-
Rea, S.L.; Wu, D.; Cypser, J.R.; Vaupel, J.W.; Johnson, T.E. A stress-sensitive reporter predicts longevity in isogenic populations of Caenorhabditis elegans. Nat. Genet., 2005, 37(8), 894-898.
-
(2005)
Nat. Genet
, vol.37
, Issue.8
, pp. 894-898
-
-
Rea, S.L.1
Wu, D.2
Cypser, J.R.3
Vaupel, J.W.4
Johnson, T.E.5
-
27
-
-
67650757278
-
Expression of hsp22 and hsp70 transgenes is partially predictive of drosophila survival under normal and stress conditions
-
Yang, J.; Tower, J. Expression of hsp22 and hsp70 transgenes is partially predictive of drosophila survival under normal and stress conditions. J. Gerontol. A Biol. Sci. Med. Sci., 2009, 64(8), 828-838.
-
(2009)
J. Gerontol. A Biol. Sci. Med. Sci
, vol.64
, Issue.8
, pp. 828-838
-
-
Yang, J.1
Tower, J.2
-
28
-
-
25144459980
-
The metabolic syndrome- a new worldwide definition
-
Alberti, K.G.; Zimmet, P.; Shaw, J. The metabolic syndrome- a new worldwide definition. Lancet, 2005, 366(9491), 1059-1062.
-
(2005)
Lancet
, vol.366
, Issue.9491
, pp. 1059-1062
-
-
Alberti, K.G.1
Zimmet, P.2
Shaw, J.3
-
29
-
-
33845881411
-
Mechanisms linking obesity to insulin resistance and type 2 diabetes
-
Kahn, S.E.; Hull, R.L.; Utzschneider, K.M. Mechanisms linking obesity to insulin resistance and type 2 diabetes. Nature, 2006, 444(7121), 840-846.
-
(2006)
Nature
, vol.444
, Issue.7121
, pp. 840-846
-
-
Kahn, S.E.1
Hull, R.L.2
Utzschneider, K.M.3
-
30
-
-
36749055907
-
Effect of glycation on alpha-crystallin structure and chaperone-like function
-
Kumar, P.A.; Kumar, M.S.; Reddy, G.B. Effect of glycation on alpha-crystallin structure and chaperone-like function. Biochem. J., 2007, 408(2), 251-258.
-
(2007)
Biochem. J
, vol.408
, Issue.2
, pp. 251-258
-
-
Kumar, P.A.1
Kumar, M.S.2
Reddy, G.B.3
-
31
-
-
34047179973
-
Ubiquitinated-protein aggregates form in pancreatic beta-cells during diabetes-induced oxidative stress and are regulated by autophagy
-
Kaniuk, N.A.; Kiraly, M.; Bates, H.; Vranic, M.; Volchuk, A.; Brumell, J.H. Ubiquitinated-protein aggregates form in pancreatic beta-cells during diabetes-induced oxidative stress and are regulated by autophagy. Diabetes, 2007, 56(4), 930-939.
-
(2007)
Diabetes
, vol.56
, Issue.4
, pp. 930-939
-
-
Kaniuk, N.A.1
Kiraly, M.2
Bates, H.3
Vranic, M.4
Volchuk, A.5
Brumell, J.H.6
-
32
-
-
66149106728
-
Tissue-specific regulation and expression of heat shock proteins in type 2 diabetic monkeys
-
Kavanagh, K.; Zhang, L.; Wagner, J.D. Tissue-specific regulation and expression of heat shock proteins in type 2 diabetic monkeys. Cell Stress Chaperones, 2009, 14(3), 291-299.
-
(2009)
Cell Stress Chaperones
, vol.14
, Issue.3
, pp. 291-299
-
-
Kavanagh, K.1
Zhang, L.2
Wagner, J.D.3
-
33
-
-
0036227062
-
Decreased expression of heat shock protein 72 in skeletal muscle of patients with type 2 diabetes correlates with insulin resistance
-
Kurucz, I.; Morva, A.; Vaag, A.; Eriksson, K.F.; Huang, X.; Groop, L.; Koranyi, L. Decreased expression of heat shock protein 72 in skeletal muscle of patients with type 2 diabetes correlates with insulin resistance. Diabetes, 2002, 51(4), 1102-1109.
-
(2002)
Diabetes
, vol.51
, Issue.4
, pp. 1102-1109
-
-
Kurucz, I.1
Morva, A.2
Vaag, A.3
Eriksson, K.F.4
Huang, X.5
Groop, L.6
Koranyi, L.7
-
34
-
-
63849147182
-
Heat shock proteins in diabetes and wound healing
-
Atalay, M.; Oksala, N.; Lappalainen, J.; Laaksonen, D.E.; Sen, C.K.; Roy, S. Heat shock proteins in diabetes and wound healing. Curr. Protein. Pept. Sci., 2009, 10(1), 85-95.
-
(2009)
Curr. Protein. Pept. Sci
, vol.10
, Issue.1
, pp. 85-95
-
-
Atalay, M.1
Oksala, N.2
Lappalainen, J.3
Laaksonen, D.E.4
Sen, C.K.5
Roy, S.6
-
35
-
-
64049105985
-
Inflammation, heat shock proteins, and type 2 diabetes
-
Hooper, P.L.; Hooper, P.L. Inflammation, heat shock proteins, and type 2 diabetes. Cell Stress Chaperones, 2009, 14(2), 113-115.
-
(2009)
Cell Stress Chaperones
, vol.14
, Issue.2
, pp. 113-115
-
-
Hooper, P.L.1
Hooper, P.L.2
-
36
-
-
0036090023
-
Invited review: Interplay between molecular chaperones and signaling pathways in survival of heat shock
-
Gabai, V.L.; Sherman, M.Y. Invited review: Interplay between molecular chaperones and signaling pathways in survival of heat shock. J. Appl. Physiol., 2002, 92(4), 1743-1748.
-
(2002)
J. Appl. Physiol
, vol.92
, Issue.4
, pp. 1743-1748
-
-
Gabai, V.L.1
Sherman, M.Y.2
-
37
-
-
58349084660
-
High glucose-induced IKK-Hsp-90 interaction contributes to endothelial dysfunction
-
Mohan, S.; Konopinski, R.; Yan, B.; Centonze, V.E.; Natarajan, M. High glucose-induced IKK-Hsp-90 interaction contributes to endothelial dysfunction. Am. J. Physiol. Cell Physiol., 2009, 296(1), C182-192.
-
(2009)
Am. J. Physiol. Cell Physiol
, vol.296
, Issue.1
-
-
Mohan, S.1
Konopinski, R.2
Yan, B.3
Centonze, V.E.4
Natarajan, M.5
-
38
-
-
34248223712
-
Protein kinase A-dependent translocation of Hsp90 alpha impairs endothelial nitric-oxide synthase activity in high glucose and diabetes
-
Lei, H.; Venkatakrishnan, A.; Yu, S.; Kazlauskas, A. Protein kinase A-dependent translocation of Hsp90 alpha impairs endothelial nitric-oxide synthase activity in high glucose and diabetes. J. Biol. Chem., 2007, 282(13), 9364-9371.
-
(2007)
J. Biol. Chem
, vol.282
, Issue.13
, pp. 9364-9371
-
-
Lei, H.1
Venkatakrishnan, A.2
Yu, S.3
Kazlauskas, A.4
-
39
-
-
33644747421
-
Activation of the AMP-activated kinase by antidiabetes drug metformin stimulates nitric oxide synthesis in vivo by promoting the association of heat shock protein 90 and endothelial nitric oxide synthase
-
Davis, B.J.; Xie, Z.; Viollet, B.; Zou, M.H. Activation of the AMP-activated kinase by antidiabetes drug metformin stimulates nitric oxide synthesis in vivo by promoting the association of heat shock protein 90 and endothelial nitric oxide synthase. Diabetes, 2006, 55(2), 496-505.
-
(2006)
Diabetes
, vol.55
, Issue.2
, pp. 496-505
-
-
Davis, B.J.1
Xie, Z.2
Viollet, B.3
Zou, M.H.4
-
40
-
-
66249092436
-
Berberine prevents hyperglycemia-induced endothelial injury and enhances vasodilatation via adenosine monophosphate-activated protein kinase and endothelial nitric oxide synthase
-
Wang, Y.; Huang, Y.; Lam, K.S.; Li, Y.; Wong, W.T.; Ye, H.; Lau, C.W.; Vanhoutte, P.M.; Xu, A. Berberine prevents hyperglycemia-induced endothelial injury and enhances vasodilatation via adenosine monophosphate-activated protein kinase and endothelial nitric oxide synthase. Cardiovasc. Res., 2009, 82(3), 484-492.
-
(2009)
Cardiovasc. Res
, vol.82
, Issue.3
, pp. 484-492
-
-
Wang, Y.1
Huang, Y.2
Lam, K.S.3
Li, Y.4
Wong, W.T.5
Ye, H.6
Lau, C.W.7
Vanhoutte, P.M.8
Xu, A.9
-
41
-
-
62749130586
-
Heat treatment improves glucose tolerance and prevents skeletal muscle insulin resistance in rats fed a high-fat diet
-
Gupte, A.A.; Bomhoff, G.L.; Swerdlow, R.H.; Geiger, P.C. Heat treatment improves glucose tolerance and prevents skeletal muscle insulin resistance in rats fed a high-fat diet. Diabetes, 2009, 58(3), 567-578.
-
(2009)
Diabetes
, vol.58
, Issue.3
, pp. 567-578
-
-
Gupte, A.A.1
Bomhoff, G.L.2
Swerdlow, R.H.3
Geiger, P.C.4
-
42
-
-
0036291435
-
Effect of BRX-220 against peripheral neuropathy and insulin resistance in diabetic rat models
-
Kurthy, M.; Mogyorosi, T.; Nagy, K.; Kukorelli, T.; Jednakovits, A.; Talosi, L.; Biro, K. Effect of BRX-220 against peripheral neuropathy and insulin resistance in diabetic rat models. Ann. N Y. Acad. Sci., 2002, 967, 482-489.
-
(2002)
Ann. N Y. Acad. Sci
, vol.967
, pp. 482-489
-
-
Kurthy, M.1
Mogyorosi, T.2
Nagy, K.3
Kukorelli, T.4
Jednakovits, A.5
Talosi, L.6
Biro, K.7
-
43
-
-
40349096251
-
HSP72 protects against obesity-induced insulin resistance
-
Chung, J.; Nguyen, A.K.; Henstridge, D.C.; Holmes, A.G.; Chan, M.H.; Mesa, J.L.; Lancaster, G.I.; Southgate, R.J.; Bruce, C.R.; Duffy, S.J.; Horvath, I.; Mestril, R.; Watt, M.J.; Hooper, P.L.; Kingwell, B.A.; Vigh, L.; Hevener, A.; Febbraio, M.A. HSP72 protects against obesity-induced insulin resistance. Proc. Natl. Acad. Sci. USA, 2008, 105(5), 1739-1744.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, Issue.5
, pp. 1739-1744
-
-
Chung, J.1
Nguyen, A.K.2
Henstridge, D.C.3
Holmes, A.G.4
Chan, M.H.5
Mesa, J.L.6
Lancaster, G.I.7
Southgate, R.J.8
Bruce, C.R.9
Duffy, S.J.10
Horvath, I.11
Mestril, R.12
Watt, M.J.13
Hooper, P.L.14
Kingwell, B.A.15
Vigh, L.16
Hevener, A.17
Febbraio, M.A.18
-
44
-
-
67949109687
-
Improvement of insulin sensitivity by a novel drug, BGP-15, in insulin-resistant patients: A proof of concept randomized double-blind clinical trial
-
Literáti-Nagy, B.; Kulcsár, E.; Literáti-Nagy, Z.; Buday, B.; Péterfai, E.; Horváth, T.; Tory, K.; Kolonics, A.; Fleming, A.; Mandl, J.; Korányi, L. Improvement of insulin sensitivity by a novel drug, BGP-15, in insulin-resistant patients: a proof of concept randomized double-blind clinical trial. Horm. Metab. Res., 2009, 41(5), 374-380.
-
(2009)
Horm. Metab. Res
, vol.41
, Issue.5
, pp. 374-380
-
-
Literáti-Nagy, B.1
Kulcsár, E.2
Literáti-Nagy, Z.3
Buday, B.4
Péterfai, E.5
Horváth, T.6
Tory, K.7
Kolonics, A.8
Fleming, A.9
Mandl, J.10
Korányi, L.11
-
45
-
-
34848926209
-
Diverse cellular functions of the Hsp90 molecular chaperone uncovered using systems approaches
-
McClellan, A.J.; Xia, Y.; Deutschbauer, A.M.; Davis, R.W.; Gerstein, M.; Frydman, J. Diverse cellular functions of the Hsp90 molecular chaperone uncovered using systems approaches. Cell, 2007, 131(1), 121-135.
-
(2007)
Cell
, vol.131
, Issue.1
, pp. 121-135
-
-
McClellan, A.J.1
Xia, Y.2
Deutschbauer, A.M.3
Davis, R.W.4
Gerstein, M.5
Frydman, J.6
-
46
-
-
0031549576
-
Seminars in medicine of the Beth Israel Deaconess Medical Center. Caloric intake and aging
-
Weindruch, R.; Sohal, R.S. Seminars in medicine of the Beth Israel Deaconess Medical Center. Caloric intake and aging. N. Engl. J. Med., 1997, 337(14), 986-994.
-
(1997)
N. Engl. J. Med
, vol.337
, Issue.14
, pp. 986-994
-
-
Weindruch, R.1
Sohal, R.S.2
-
47
-
-
22744445281
-
Overview of caloric restriction and ageing
-
Masoro, E.J. Overview of caloric restriction and ageing. Mech. Ageing Dev., 2005, 126(9), 913-922.
-
(2005)
Mech. Ageing Dev
, vol.126
, Issue.9
, pp. 913-922
-
-
Masoro, E.J.1
-
48
-
-
0027154719
-
Expression of heat shock protein 70 is altered by age and diet at the level of transcription
-
Heydari, A.R.; Wu, B.; Takahashi, R.; Strong, R.; Richardson, A. Expression of heat shock protein 70 is altered by age and diet at the level of transcription. Mol. Cell. Biol., 1993, 13(5), 2909-1918.
-
(1993)
Mol. Cell. Biol
, vol.13
, Issue.5
, pp. 2909-1918
-
-
Heydari, A.R.1
Wu, B.2
Takahashi, R.3
Strong, R.4
Richardson, A.5
-
49
-
-
0029870841
-
Effect of caloric restriction on the expression of heat shock protein 70 and the activation of heat shock transcription factor 1
-
Heydari, A.R.; You, S.; Takahashi, R.; Gutsmann, A.; Sarge, K.D.; Richardson, A. Effect of caloric restriction on the expression of heat shock protein 70 and the activation of heat shock transcription factor 1. Dev. Genet., 1996, 18(2), 114-124.
-
(1996)
Dev. Genet
, vol.18
, Issue.2
, pp. 114-124
-
-
Heydari, A.R.1
You, S.2
Takahashi, R.3
Gutsmann, A.4
Sarge, K.D.5
Richardson, A.6
-
50
-
-
0033976575
-
Caloric restriction improves thermotolerance and reduces hyperthermia-induced cellular damage in old rats
-
Hall, D.M.; Oberley, T.D.; Moseley, P.M.; Buettner, G.R.; Oberley, L.W.; Weindruch, R.; Kregel, K.C. Caloric restriction improves thermotolerance and reduces hyperthermia-induced cellular damage in old rats. FASEB J., 2000, 14(1),78-86.
-
(2000)
FASEB J
, vol.14
, Issue.1
, pp. 78-86
-
-
Hall, D.M.1
Oberley, T.D.2
Moseley, P.M.3
Buettner, G.R.4
Oberley, L.W.5
Weindruch, R.6
Kregel, K.C.7
-
51
-
-
0029872930
-
Caloric restriction increases the expression of heat shock protein in the gut
-
Ehrenfried, J.A.; Evers, B.M.; Chu, K.U.; Townsend, C.M.Jr.; Thompson, J.C. Caloric restriction increases the expression of heat shock protein in the gut. Ann. Surg., 1996, 223(5), 592-599.
-
(1996)
Ann. Surg
, vol.223
, Issue.5
, pp. 592-599
-
-
Ehrenfried, J.A.1
Evers, B.M.2
Chu, K.U.3
Townsend Jr, C.M.4
Thompson, J.C.5
-
52
-
-
12344335611
-
Life long calorie restriction increases heat shock proteins and proteasome activity in soleus muscles of Fisher 344 rats
-
Selsby, J.T.; Judge, A.R.; Yimlamai, T.; Leeuwenburgh, C.; Dodd S.L. Life long calorie restriction increases heat shock proteins and proteasome activity in soleus muscles of Fisher 344 rats. Exp. Gerontol., 2005, 40(1-2), 37-42.
-
(2005)
Exp. Gerontol
, vol.40
, Issue.1-2
, pp. 37-42
-
-
Selsby, J.T.1
Judge, A.R.2
Yimlamai, T.3
Leeuwenburgh, C.4
Dodd, S.L.5
-
53
-
-
23044439886
-
Preservation of heat stress induced myocardial hsp 72 in aged animals following caloric restriction
-
Frier, B.; Locke, M. Preservation of heat stress induced myocardial hsp 72 in aged animals following caloric restriction. Exp. Gerontol., 2005, 40(7), 615-617.
-
(2005)
Exp. Gerontol
, vol.40
, Issue.7
, pp. 615-617
-
-
Frier, B.1
Locke, M.2
-
54
-
-
33745840820
-
Effects of aging and antiaging caloric restrictions on carbonyl and heat shock protein levels and expression
-
Colotti, C.; Cavallini, G.; Vitale, R.L.; Donati, A.; Maltinti, M.; Del Ry, S.; Bergamini, E.; Giannessi, D. Effects of aging and antiaging caloric restrictions on carbonyl and heat shock protein levels and expression. Biogerontology, 2005, 6(6), 397-406.
-
(2005)
Biogerontology
, vol.6
, Issue.6
, pp. 397-406
-
-
Colotti, C.1
Cavallini, G.2
Vitale, R.L.3
Donati, A.4
Maltinti, M.5
Del Ry, S.6
Bergamini, E.7
Giannessi, D.8
-
55
-
-
63549138319
-
Molecular architecture of myelinated peripheral nerves is supported by calorie restriction with aging
-
Rangaraju, S.; Hankins, D.; Madorsky, I.; Madorsky, E.; Lee, W.H.; Carter, C.S.; Leeuwenburgh, C.; Notterpek, L. Molecular architecture of myelinated peripheral nerves is supported by calorie restriction with aging. Aging Cell, 2009, 8(2), 178-191.
-
(2009)
Aging Cell
, vol.8
, Issue.2
, pp. 178-191
-
-
Rangaraju, S.1
Hankins, D.2
Madorsky, I.3
Madorsky, E.4
Lee, W.H.5
Carter, C.S.6
Leeuwenburgh, C.7
Notterpek, L.8
-
56
-
-
52449135100
-
-
Allard, J.S.; Heilbronn, L.K.; Smith, C.; Hunt, N.D.; Ingram, D.K.; Ravussin, E.; Pennington CALERIE Team; de Cabo, R. In vitro cellular adaptations of indicators of longevity in response to treatment with serum collected from humans on calorie restricted diets. PLoS One, 2008, 3(9),e3211.
-
Allard, J.S.; Heilbronn, L.K.; Smith, C.; Hunt, N.D.; Ingram, D.K.; Ravussin, E.; Pennington CALERIE Team; de Cabo, R. In vitro cellular adaptations of indicators of longevity in response to treatment with serum collected from humans on calorie restricted diets. PLoS One, 2008, 3(9),e3211.
-
-
-
-
57
-
-
0035845492
-
Genomic profiling of short- and long-term caloric restriction effects in the liver of aging mice
-
Cao, S.X.; Dhahbi, J.M.; Mote, P.L.; Spindler, S.R. Genomic profiling of short- and long-term caloric restriction effects in the liver of aging mice. Proc. Natl. Acad. Sci. USA, 2001, 98(19), 10630-10635.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, Issue.19
, pp. 10630-10635
-
-
Cao, S.X.1
Dhahbi, J.M.2
Mote, P.L.3
Spindler, S.R.4
-
58
-
-
0035942222
-
Influences of aging and caloric restriction on the transcriptional profile of skeletal muscle from rhesus monkeys
-
Kayo, T.; Allison, D.B.; Weindruch, R.; Prolla, T.A. Influences of aging and caloric restriction on the transcriptional profile of skeletal muscle from rhesus monkeys. Proc. Natl. Acad. Sci. USA, 2001, 98(9), 5093-5098.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, Issue.9
, pp. 5093-5098
-
-
Kayo, T.1
Allison, D.B.2
Weindruch, R.3
Prolla, T.A.4
-
59
-
-
0037418339
-
Dietary restriction normalizes glucose metabolism and BDNF levels, slows disease progression, and increases survival in huntingtin mutant mice
-
Duan, W.; Guo, Z.; Jiang, H.; Ware, M.; Li. X.J.; Mattson, M.P. Dietary restriction normalizes glucose metabolism and BDNF levels, slows disease progression, and increases survival in huntingtin mutant mice. Proc. Natl. Acad. Sci. USA, 2003, 100(5), 2911-2916.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, Issue.5
, pp. 2911-2916
-
-
Duan, W.1
Guo, Z.2
Jiang, H.3
Ware, M.4
Li, X.J.5
Mattson, M.P.6
-
60
-
-
43449138491
-
Dietary restriction suppresses proteotoxicity and enhances longevity by an hsf-1-dependent mechanism in Caenorhabditis elegans
-
Steinkraus, K.A.; Smith, E.D.; Davis, C.; Carr, D.; Pendergrass, W.R.; Sutphin, G.L.; Kennedy, B.K.; Kaeberlein, M. Dietary restriction suppresses proteotoxicity and enhances longevity by an hsf-1-dependent mechanism in Caenorhabditis elegans. Aging Cell, 2008, 7(3), 394-404.
-
(2008)
Aging Cell
, vol.7
, Issue.3
, pp. 394-404
-
-
Steinkraus, K.A.1
Smith, E.D.2
Davis, C.3
Carr, D.4
Pendergrass, W.R.5
Sutphin, G.L.6
Kennedy, B.K.7
Kaeberlein, M.8
-
61
-
-
0033168080
-
2-Deoxy-D-glucose protects hippocampal neurons against excitotoxic and oxidative injury: Evidence for the involvement of stress proteins
-
Lee, J.; Bruce-Keller, A.J.; Kruman, Y.; Chan, S.L.; Mattson, M.P. 2-Deoxy-D-glucose protects hippocampal neurons against excitotoxic and oxidative injury: evidence for the involvement of stress proteins. J. Neurosci. Res., 1999, 57(1), 48-61.
-
(1999)
J. Neurosci. Res
, vol.57
, Issue.1
, pp. 48-61
-
-
Lee, J.1
Bruce-Keller, A.J.2
Kruman, Y.3
Chan, S.L.4
Mattson, M.P.5
-
62
-
-
0033766916
-
In vivo 2-deoxyglucose administration preserves glucose and glutamate transport and mitochondrial function in cortical synaptic terminals after exposure to amyloid betapeptide and iron: Evidence for a stress response
-
Guo, Z.H.; Mattson, M.P. In vivo 2-deoxyglucose administration preserves glucose and glutamate transport and mitochondrial function in cortical synaptic terminals after exposure to amyloid betapeptide and iron: evidence for a stress response. Exp. Neurol., 2000, 166(1), 173-179.
-
(2000)
Exp. Neurol
, vol.166
, Issue.1
, pp. 173-179
-
-
Guo, Z.H.1
Mattson, M.P.2
-
63
-
-
4444315286
-
Repression of thermotolerance in Dunning R3327 prostate carcinoma cells by 2-deoxy-glucose
-
Roigas, J.; Jensen, C.A.; Wallen, E.S.; Loening, S.A.; Wharton, W.; Moseley, P.L. Repression of thermotolerance in Dunning R3327 prostate carcinoma cells by 2-deoxy-glucose. Int. J. Hyperthermia, 2004, 20(6),557-566.
-
(2004)
Int. J. Hyperthermia
, vol.20
, Issue.6
, pp. 557-566
-
-
Roigas, J.1
Jensen, C.A.2
Wallen, E.S.3
Loening, S.A.4
Wharton, W.5
Moseley, P.L.6
-
64
-
-
50949096364
-
Calorie restriction and aging: The ultimate "cleansing diet
-
Cuervo, A.M. Calorie restriction and aging: the ultimate "cleansing diet". J. Gerontol. A Biol. Sci. Med. Sci., 2008, 63(6), 547-549.
-
(2008)
J. Gerontol. A Biol. Sci. Med. Sci
, vol.63
, Issue.6
, pp. 547-549
-
-
Cuervo, A.M.1
-
65
-
-
50949086260
-
Effect of aging and anti-aging caloric restriction on the endocrine regulation of rat liver autophagy
-
Donati, A.; Recchia, G.; Cavallini, G.; Bergamini E. Effect of aging and anti-aging caloric restriction on the endocrine regulation of rat liver autophagy. J. Gerontol. A Biol. Sci. Med. Sci., 2008, 63(6), 550-555.
-
(2008)
J. Gerontol. A Biol. Sci. Med. Sci
, vol.63
, Issue.6
, pp. 550-555
-
-
Donati, A.1
Recchia, G.2
Cavallini, G.3
Bergamini, E.4
-
66
-
-
40149105890
-
A role for autophagy in the extension of lifespan by dietary restriction in C. elegans
-
Hansen, M.; Chandra, A.; Mitic, L.L.; Onken, B.; Driscoll, M.; Kenyon, C. A role for autophagy in the extension of lifespan by dietary restriction in C. elegans. PLoS Genet., 2008, 4(2), e24.
-
(2008)
PLoS Genet
, vol.4
, Issue.2
-
-
Hansen, M.1
Chandra, A.2
Mitic, L.L.3
Onken, B.4
Driscoll, M.5
Kenyon, C.6
-
67
-
-
41449102024
-
Longevity pathways converge on autophagy genes to regulate life span in Caenorhabditis elegans
-
Tóth, M.L.; Sigmond, T.; Borsos, E.; Barna, J.; Erdélyi, P.; Takács-Vellai, K.; Orosz, L.; Kovács, A.L.; Csikós, G.; Sass, M.; Vellai, T. Longevity pathways converge on autophagy genes to regulate life span in Caenorhabditis elegans. Autophagy, 2008, 4(3), 330-338.
-
(2008)
Autophagy
, vol.4
, Issue.3
, pp. 330-338
-
-
Tóth, M.L.1
Sigmond, T.2
Borsos, E.3
Barna, J.4
Erdélyi, P.5
Takács-Vellai, K.6
Orosz, L.7
Kovács, A.L.8
Csikós, G.9
Sass, M.10
Vellai, T.11
-
68
-
-
0037470501
-
The endocrine regulation of aging by insulin-like signals
-
Tatar, M.; Bartke, A.; Antebi, A. The endocrine regulation of aging by insulin-like signals. Science, 2003, 299(5611), 1346-1351.
-
(2003)
Science
, vol.299
, Issue.5611
, pp. 1346-1351
-
-
Tatar, M.1
Bartke, A.2
Antebi, A.3
-
69
-
-
13944269223
-
The plasticity of aging: Insights from long-lived mutants
-
Kenyon, C. The plasticity of aging: insights from long-lived mutants. Cell, 2005, 120(4), 449-460.
-
(2005)
Cell
, vol.120
, Issue.4
, pp. 449-460
-
-
Kenyon, C.1
-
70
-
-
0742323000
-
Regulation of longevity in Caenorhabditis elegans by heat shock factor and molecular chaperones
-
Morley, J.F.; Morimoto, R.I. Regulation of longevity in Caenorhabditis elegans by heat shock factor and molecular chaperones. Mol. Biol. Cell., 2004, 15(2), 657-664.
-
(2004)
Mol. Biol. Cell
, vol.15
, Issue.2
, pp. 657-664
-
-
Morley, J.F.1
Morimoto, R.I.2
-
71
-
-
0036678146
-
The threshold for polyglutamine-expansion protein aggregation and cellular toxicity is dynamic and influenced by aging in Caenorhabditis elegans
-
Morley, J.F.; Brignull, H.R.; Weyers, J.J.; Morimoto, R.I. The threshold for polyglutamine-expansion protein aggregation and cellular toxicity is dynamic and influenced by aging in Caenorhabditis elegans. Proc. Natl. Acad. Sci. USA, 2002, 99(16), 10417-10422.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, Issue.16
, pp. 10417-10422
-
-
Morley, J.F.1
Brignull, H.R.2
Weyers, J.J.3
Morimoto, R.I.4
-
72
-
-
34848850156
-
An AMPK-FOXO pathway mediates longevity induced by a novel method of dietary restriction in C. elegans
-
Greer, E.L.; Dowlatshahi, D.; Banko, M.R.; Villen, J.; Hoang, K.; Blanchard, D.; Gygi, S.P.; Brunet, A. An AMPK-FOXO pathway mediates longevity induced by a novel method of dietary restriction in C. elegans. Curr. Biol., 2007, 17(19), 1646-1656.
-
(2007)
Curr. Biol
, vol.17
, Issue.19
, pp. 1646-1656
-
-
Greer, E.L.1
Dowlatshahi, D.2
Banko, M.R.3
Villen, J.4
Hoang, K.5
Blanchard, D.6
Gygi, S.P.7
Brunet, A.8
-
73
-
-
63549108476
-
Different dietary restriction regimens extend lifespan by both independent and overlapping genetic pathways in C. elegans
-
Greer, E. L.; Brunet, A. Different dietary restriction regimens extend lifespan by both independent and overlapping genetic pathways in C. elegans. Aging Cell, 2009, 8(2), 113-127.
-
(2009)
Aging Cell
, vol.8
, Issue.2
, pp. 113-127
-
-
Greer, E.L.1
Brunet, A.2
-
74
-
-
33751407431
-
The longevity effect of dietary restriction in Caenorhabditis elegans
-
Houthoofd, K.; Vanfleteren, J.R. The longevity effect of dietary restriction in Caenorhabditis elegans. Exp. Gerontol., 2006, 41(10), 1026-1031.
-
(2006)
Exp. Gerontol
, vol.41
, Issue.10
, pp. 1026-1031
-
-
Houthoofd, K.1
Vanfleteren, J.R.2
-
75
-
-
0032573178
-
The genetics of caloric restriction in Caenorhabditis elegans
-
Lakowski, B.; Hekimi, S. The genetics of caloric restriction in Caenorhabditis elegans. Proc. Natl. Acad. Sci. USA, 1998, 95(22), 13091-13096.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, Issue.22
, pp. 13091-13096
-
-
Lakowski, B.1
Hekimi, S.2
-
76
-
-
34249888736
-
PHA-4/Foxa mediates diet-restriction-induced longevity of C. elegans
-
Panowski, S.H.; Wolff, S.; Aguilaniu, H.; Durieux, J.; Dillin, A. PHA-4/Foxa mediates diet-restriction-induced longevity of C. elegans. Nature, 2007, 447(7144), 550-555.
-
(2007)
Nature
, vol.447
, Issue.7144
, pp. 550-555
-
-
Panowski, S.H.1
Wolff, S.2
Aguilaniu, H.3
Durieux, J.4
Dillin, A.5
-
77
-
-
34249891333
-
Two neurons mediate diet-restriction-induced longevity in C. elegans
-
Bishop, N.A.; Guarente, L. Two neurons mediate diet-restriction-induced longevity in C. elegans. Nature, 2007, 447(7144), 545-549.
-
(2007)
Nature
, vol.447
, Issue.7144
, pp. 545-549
-
-
Bishop, N.A.1
Guarente, L.2
-
78
-
-
40549146580
-
Role of dFOXO in lifespan extension by dietary restriction in Drosophila melanogaster: Not required, but its activity modulates the response
-
Giannakou, M.E.; Goss, M.; Partridge, L. Role of dFOXO in lifespan extension by dietary restriction in Drosophila melanogaster: not required, but its activity modulates the response. Aging Cell, 2008, 7(2), 187-198.
-
(2008)
Aging Cell
, vol.7
, Issue.2
, pp. 187-198
-
-
Giannakou, M.E.1
Goss, M.2
Partridge, L.3
-
79
-
-
44349145008
-
Dietary restriction of Caenorhabditis elegans by axenic culture reflects nutritional requirement for constituents provided by metabolically active microbes
-
Lenaerts, I.; Walker, G.A.; Van Hoorebeke, L.; Gems, D.; Vanfleteren J.R. Dietary restriction of Caenorhabditis elegans by axenic culture reflects nutritional requirement for constituents provided by metabolically active microbes. J. Gerontol. A. Biol. Sci. Med. Sci., 2008, 63(3), 242-252.
-
(2008)
J. Gerontol. A. Biol. Sci. Med. Sci
, vol.63
, Issue.3
, pp. 242-252
-
-
Lenaerts, I.1
Walker, G.A.2
Van Hoorebeke, L.3
Gems, D.4
Vanfleteren, J.R.5
-
80
-
-
33751250243
-
Lifespan extension in Caenorhabditis elegans by complete removal of food
-
Kaeberlein, T.L.; Smith, E.D.; Tsuchiya, M.; Welton, K.L.; Thomas, J.H.; Fields, S.; Kennedy, B.K.; Kaeberlein, M. Lifespan extension in Caenorhabditis elegans by complete removal of food. Aging Cell, 2006, 5(6), 487-494.
-
(2006)
Aging Cell
, vol.5
, Issue.6
, pp. 487-494
-
-
Kaeberlein, T.L.1
Smith, E.D.2
Tsuchiya, M.3
Welton, K.L.4
Thomas, J.H.5
Fields, S.6
Kennedy, B.K.7
Kaeberlein, M.8
-
81
-
-
33751203889
-
Dietary deprivation extends lifespan in Caenorhabditis elegans
-
Lee, G.D.; Wilson, M.A.; Zhu, M.; Wolkow, C.A.; de Cabo, R.; Ingram, D.K.; Zou, S. Dietary deprivation extends lifespan in Caenorhabditis elegans. Aging Cell, 2006, 5(6), 515-524.
-
(2006)
Aging Cell
, vol.5
, Issue.6
, pp. 515-524
-
-
Lee, G.D.1
Wilson, M.A.2
Zhu, M.3
Wolkow, C.A.4
de Cabo, R.5
Ingram, D.K.6
Zou, S.7
-
82
-
-
44649170501
-
Age- and calorie-independent life span extension from dietary restriction by bacterial deprivation in Caenorhabditis elegans
-
Smith, E.D.; Kaeberlein, T.L.; Lydum, B.T.; Sager, J.; Welton, K.L.; Kennedy, B.K.; Kaeberlein, M. Age- and calorie-independent life span extension from dietary restriction by bacterial deprivation in Caenorhabditis elegans. BMC Dev. Biol., 2008, 8, 49.
-
(2008)
BMC Dev. Biol
, vol.8
, pp. 49
-
-
Smith, E.D.1
Kaeberlein, T.L.2
Lydum, B.T.3
Sager, J.4
Welton, K.L.5
Kennedy, B.K.6
Kaeberlein, M.7
-
83
-
-
33846423520
-
Lifespan extension by conditions that inhibit translation in Caenorhabditis elegans
-
Hansen, M.; Taubert, S.; Crawford, D.; Libina, N.; Lee, S.J.; Kenyon, C. Lifespan extension by conditions that inhibit translation in Caenorhabditis elegans. Aging Cell, 2007, 6(1), 95-110.
-
(2007)
Aging Cell
, vol.6
, Issue.1
, pp. 95-110
-
-
Hansen, M.1
Taubert, S.2
Crawford, D.3
Libina, N.4
Lee, S.J.5
Kenyon, C.6
-
84
-
-
33847199335
-
eIF4E function in somatic cells modulates ageing in Caenorhabditis elegans
-
Syntichaki, P.; Troulinaki, K,; Tavernarakis, N. eIF4E function in somatic cells modulates ageing in Caenorhabditis elegans. Nature, 2007, 445(7130), 922-926.
-
(2007)
Nature
, vol.445
, Issue.7130
, pp. 922-926
-
-
Syntichaki, P.1
Troulinaki, K.2
Tavernarakis, N.3
-
85
-
-
2942598422
-
Genome-wide analysis of the biology of stress responses through heat shock transcription factor
-
Hahn, J.S.; Hu, Z.; Thiele, D.J.; Iyer, V.R. Genome-wide analysis of the biology of stress responses through heat shock transcription factor. Mol. Cell. Biol., 2004, 24(12), 5249-5256.
-
(2004)
Mol. Cell. Biol
, vol.24
, Issue.12
, pp. 5249-5256
-
-
Hahn, J.S.1
Hu, Z.2
Thiele, D.J.3
Iyer, V.R.4
-
86
-
-
34548658230
-
Heat shock factor 1 is a powerful multifaceted modifier of carcinogenesis
-
Dai, C.; Whitesell, L.; Rogers, A.B.; Lindquist, S. Heat shock factor 1 is a powerful multifaceted modifier of carcinogenesis. Cell, 2007, 130(6), 1005-1018.
-
(2007)
Cell
, vol.130
, Issue.6
, pp. 1005-1018
-
-
Dai, C.1
Whitesell, L.2
Rogers, A.B.3
Lindquist, S.4
-
87
-
-
0141719702
-
Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan
-
Howitz, K.T.; Bitterman, K.J.; Cohen, H.Y.; Lamming, D.W.; Lavu, S.; Wood, J.G.; Zipkin, R.E.; Chung, P.; Kisielewski, A.; Zhang, L.L.; Scherer, B.; Sinclair, D.A. Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan. Nature, 2003, 425(6954), 191-196.
-
(2003)
Nature
, vol.425
, Issue.6954
, pp. 191-196
-
-
Howitz, K.T.1
Bitterman, K.J.2
Cohen, H.Y.3
Lamming, D.W.4
Lavu, S.5
Wood, J.G.6
Zipkin, R.E.7
Chung, P.8
Kisielewski, A.9
Zhang, L.L.10
Scherer, B.11
Sinclair, D.A.12
-
88
-
-
3943071801
-
Sirtuin activators mimic caloric restriction and delay ageing in metazoans
-
Wood, J.G.; Rogina, B.; Lavu, S.; Howitz, K.; Helfand, S.L.; Tatar, M.; Sinclair, D.A. Sirtuin activators mimic caloric restriction and delay ageing in metazoans. Nature, 2004, 430(7000), 686-689.
-
(2004)
Nature
, vol.430
, Issue.7000
, pp. 686-689
-
-
Wood, J.G.1
Rogina, B.2
Lavu, S.3
Howitz, K.4
Helfand, S.L.5
Tatar, M.6
Sinclair, D.A.7
-
89
-
-
33751072349
-
Resveratrol improves health and survival of mice on a high-calorie diet
-
Baur, J.A.; Pearson, K.J.; Price, N.L.; Jamieson, H.A.; Lerin, C.; Kalra, A.; Prabhu, V.V.; Allard, J.S.; Lopez-Lluch, G.; Lewis, K.; Pistell, P.J.; Poosala, S.; Becker, K.G.; Boss, O.; Gwinn, D.; Wang, M.; Ramaswamy, S.; Fishbein, K.W.; Spencer, R.G.; Lakatta, E.G.; Le Couteur, D.; Shaw, R.J.; Navas, P.; Puigserver, P.; Ingram, D.K.; de Cabo, R.; Sinclair, D.A. Resveratrol improves health and survival of mice on a high-calorie diet. Nature, 2006, 444(7117), 337-342.
-
(2006)
Nature
, vol.444
, Issue.7117
, pp. 337-342
-
-
Baur, J.A.1
Pearson, K.J.2
Price, N.L.3
Jamieson, H.A.4
Lerin, C.5
Kalra, A.6
Prabhu, V.V.7
Allard, J.S.8
Lopez-Lluch, G.9
Lewis, K.10
Pistell, P.J.11
Poosala, S.12
Becker, K.G.13
Boss, O.14
Gwinn, D.15
Wang, M.16
Ramaswamy, S.17
Fishbein, K.W.18
Spencer, R.G.19
Lakatta, E.G.20
Le Couteur, D.21
Shaw, R.J.22
Navas, P.23
Puigserver, P.24
Ingram, D.K.25
de Cabo, R.26
Sinclair, D.A.27
more..
-
90
-
-
33745962138
-
Therapeutic potential of resveratrol: The in vivo evidence
-
Baur, J.A.; Sinclair, D.A. Therapeutic potential of resveratrol: the in vivo evidence. Nat. Rev. Drug Discov., 2006, 5(6), 493-506.
-
(2006)
Nat. Rev. Drug Discov
, vol.5
, Issue.6
, pp. 493-506
-
-
Baur, J.A.1
Sinclair, D.A.2
-
91
-
-
34249750383
-
Evidence for a trade-off between survival and fitness caused by resveratrol treatment of Caenorhabditis elegans
-
Gruber, J.; Tang, S.Y.; Halliwell, B. Evidence for a trade-off between survival and fitness caused by resveratrol treatment of Caenorhabditis elegans. Ann. N. Y. Acad. Sci., 2007, 1100, 530-542.
-
(2007)
Ann. N. Y. Acad. Sci
, vol.1100
, pp. 530-542
-
-
Gruber, J.1
Tang, S.Y.2
Halliwell, B.3
-
92
-
-
34848927457
-
Effects of resveratrol on lifespan in Drosophila melanogaster and Caenorhabditis elegans
-
Bass, T.M.; Weinkove, D.; Houthoofd, K.; Gems, D.; Partridge, L. Effects of resveratrol on lifespan in Drosophila melanogaster and Caenorhabditis elegans. Mech. Ageing Dev., 2007, 128(10), 546-552.
-
(2007)
Mech. Ageing Dev
, vol.128
, Issue.10
, pp. 546-552
-
-
Bass, T.M.1
Weinkove, D.2
Houthoofd, K.3
Gems, D.4
Partridge, L.5
-
93
-
-
48349144852
-
-
Pearson, K.J.; Baur, J.A.; Lewis, K.N.; Peshkin, L.; Price, N.L.; Labinskyy, N.; Swindell, W.R.; Kamara, D.; Minor, R.K.; Perez, E.; Jamieson, H.A.; Zhang, Y.; Dunn, S.R.; Sharma, K.; Pleshko, N.; Woollett, L.A.; Csiszar, A.; Ikeno, Y.; Le Couteur, D.; Elliott, P.J.; Becker, K.G.; Navas, P.; Ingram, D.K.; Wolf, N.S.; Ungvari, Z.; Sinclair, D.A.; de Cabo, R. Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span. Cell Metab., 2008, 8(2), 157-168.
-
Pearson, K.J.; Baur, J.A.; Lewis, K.N.; Peshkin, L.; Price, N.L.; Labinskyy, N.; Swindell, W.R.; Kamara, D.; Minor, R.K.; Perez, E.; Jamieson, H.A.; Zhang, Y.; Dunn, S.R.; Sharma, K.; Pleshko, N.; Woollett, L.A.; Csiszar, A.; Ikeno, Y.; Le Couteur, D.; Elliott, P.J.; Becker, K.G.; Navas, P.; Ingram, D.K.; Wolf, N.S.; Ungvari, Z.; Sinclair, D.A.; de Cabo, R. Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span. Cell Metab., 2008, 8(2), 157-168.
-
-
-
-
94
-
-
27644585190
-
A role for SIR-2.1 regulation of ER stress response genes in determining C. elegans life span
-
Viswanathan, M.; Kim, S.K.; Berdichevsky, A.; Guarente, L. A role for SIR-2.1 regulation of ER stress response genes in determining C. elegans life span. Dev. Cell, 2005, 9(5), 605-615.
-
(2005)
Dev. Cell
, vol.9
, Issue.5
, pp. 605-615
-
-
Viswanathan, M.1
Kim, S.K.2
Berdichevsky, A.3
Guarente, L.4
-
95
-
-
12144290563
-
Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase
-
Brunet, A.; Sweeney, L.B.; Sturgill, J.F.; Chua, K.F.; Greer, P.L.; Lin, Y.; Tran, H.; Ross, S.E.; Mostoslavsky, R.; Cohen, H.Y.; Hu, L.S.; Cheng, H.L.; Jedrychowski, M.P.; Gygi, S.P.; Sinclair, D.A.; Alt, F.W.; Greenberg, M.E. Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase. Science, 2004, 303(5666), 2011-2015.
-
(2004)
Science
, vol.303
, Issue.5666
, pp. 2011-2015
-
-
Brunet, A.1
Sweeney, L.B.2
Sturgill, J.F.3
Chua, K.F.4
Greer, P.L.5
Lin, Y.6
Tran, H.7
Ross, S.E.8
Mostoslavsky, R.9
Cohen, H.Y.10
Hu, L.S.11
Cheng, H.L.12
Jedrychowski, M.P.13
Gygi, S.P.14
Sinclair, D.A.15
Alt, F.W.16
Greenberg, M.E.17
-
96
-
-
3042681042
-
Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-gamma
-
Picard, F.; Kurtev, M.; Chung, N.; Topark-Ngarm, A.; Senawong, T.; Machado De Oliveira, R.; Leid, M.; McBurney, M.W.; Guarente, L. Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-gamma. Nature, 2004, 429(6993), 771-776.
-
(2004)
Nature
, vol.429
, Issue.6993
, pp. 771-776
-
-
Picard, F.1
Kurtev, M.2
Chung, N.3
Topark-Ngarm, A.4
Senawong, T.5
Machado De Oliveira, R.6
Leid, M.7
McBurney, M.W.8
Guarente, L.9
-
97
-
-
18144411313
-
SIRT1 functionally interacts with the metabolic regulator and transcriptional coactivator PGC-1{alpha}
-
Nemoto, S.; Fergusson, M.M.; Finkel, T. SIRT1 functionally interacts with the metabolic regulator and transcriptional coactivator PGC-1{alpha}. J. Biol. Chem., 2005, 280(16), 16456-16460.
-
(2005)
J. Biol. Chem
, vol.280
, Issue.16
, pp. 16456-16460
-
-
Nemoto, S.1
Fergusson, M.M.2
Finkel, T.3
-
98
-
-
0035826271
-
Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans
-
Tissenbaum, H.A.; Guarente, L. Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans. Nature, 2001, 410(6825), 227-230.
-
(2001)
Nature
, vol.410
, Issue.6825
, pp. 227-230
-
-
Tissenbaum, H.A.1
Guarente, L.2
-
99
-
-
52749091816
-
SirT1 gain of function increases energy efficiency and prevents diabetes in mice
-
Banks, A.S.; Kon, N.; Knight, C.; Matsumoto, M.; Gutierrez-Juarez, R.; Rossetti, L.; Gu, W.; Accili, D. SirT1 gain of function increases energy efficiency and prevents diabetes in mice. Cell Metab., 2008, 8(4), 333-341.
-
(2008)
Cell Metab
, vol.8
, Issue.4
, pp. 333-341
-
-
Banks, A.S.1
Kon, N.2
Knight, C.3
Matsumoto, M.4
Gutierrez-Juarez, R.5
Rossetti, L.6
Gu, W.7
Accili, D.8
-
100
-
-
47749128879
-
Sirt1 protects against high-fat diet-induced metabolic damage
-
Pfluger, P.T.; Herranz, D.; Velasco-Miguel, S.; Serrano, M.; Tschop, M.H. Sirt1 protects against high-fat diet-induced metabolic damage. Proc. Natl. Acad. Sci. USA, 2008, 105(28), 9793-9798.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, Issue.28
, pp. 9793-9798
-
-
Pfluger, P.T.1
Herranz, D.2
Velasco-Miguel, S.3
Serrano, M.4
Tschop, M.H.5
-
101
-
-
0034703217
-
Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae
-
Lin, S.J.; Defossez, P.A.; Guarente, L. Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae. Science, 2000, 289(5487), 2126-2128.
-
(2000)
Science
, vol.289
, Issue.5487
, pp. 2126-2128
-
-
Lin, S.J.1
Defossez, P.A.2
Guarente, L.3
-
102
-
-
28244475950
-
Overlapping and distinct functions for a Caenorhabditis elegans SIR2 and DAF-16/FOXO
-
Wang, Y.; Tissenbaum, H.A. Overlapping and distinct functions for a Caenorhabditis elegans SIR2 and DAF-16/FOXO. Mech. Ageing Dev., 2006, 127(1), 48-56.
-
(2006)
Mech. Ageing Dev
, vol.127
, Issue.1
, pp. 48-56
-
-
Wang, Y.1
Tissenbaum, H.A.2
-
103
-
-
45549098657
-
SirT1 regulates energy metabolism and response to caloric restriction in mice
-
Boily, G.; Seifert, E.L.; Bevilacqua, L.; He, X.H.; Sabourin, G.; Estey, C.; Moffat, C.; Crawford, S.; Saliba, S.; Jardine, K.; Xuan, J.; Evans, M.; Harper, M.E.; McBurney, M.W. SirT1 regulates energy metabolism and response to caloric restriction in mice. PLoS ONE, 2008, 3(3), e1759.
-
(2008)
PLoS ONE
, vol.3
, Issue.3
-
-
Boily, G.1
Seifert, E.L.2
Bevilacqua, L.3
He, X.H.4
Sabourin, G.5
Estey, C.6
Moffat, C.7
Crawford, S.8
Saliba, S.9
Jardine, K.10
Xuan, J.11
Evans, M.12
Harper, M.E.13
McBurney, M.W.14
-
104
-
-
16844375290
-
Resveratrol rescues mutant polyglutamine cytotoxicity in nematode and mammalian neurons
-
Parker, J.A.; Arango, M.; Abderrahmane, S.; Lambert, E.; Tourette, C.; Catoire, H.; Neri, C. Resveratrol rescues mutant polyglutamine cytotoxicity in nematode and mammalian neurons. Nat. Genet., 2005, 37(4), 349-350.
-
(2005)
Nat. Genet
, vol.37
, Issue.4
, pp. 349-350
-
-
Parker, J.A.1
Arango, M.2
Abderrahmane, S.3
Lambert, E.4
Tourette, C.5
Catoire, H.6
Neri, C.7
-
105
-
-
34447308268
-
SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis
-
Kim, D.; Nguyen, M.D.; Dobbin, M.M.; Fischer, A.; Sananbenesi, F.; Rodgers, J.T.; Delalle, I.; Baur, J.A.; Sui, G.; Armour, S.M.; Puigserver, P.; Sinclair, D.A.; Tsai, L.H. SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis. EMBO J., 2007, 26(13), 3169-3179.
-
(2007)
EMBO J
, vol.26
, Issue.13
, pp. 3169-3179
-
-
Kim, D.1
Nguyen, M.D.2
Dobbin, M.M.3
Fischer, A.4
Sananbenesi, F.5
Rodgers, J.T.6
Delalle, I.7
Baur, J.A.8
Sui, G.9
Armour, S.M.10
Puigserver, P.11
Sinclair, D.A.12
Tsai, L.H.13
-
106
-
-
36148942866
-
Resveratrol induces the heat-shock response and protects human cells from severe heat stress
-
Putics, Á.; Végh, E.M.; Csermely, P.; Söti, C. Resveratrol induces the heat-shock response and protects human cells from severe heat stress. Antioxid. Redox Signal., 2008, 10(1), 65-75.
-
(2008)
Antioxid. Redox Signal
, vol.10
, Issue.1
, pp. 65-75
-
-
Putics, A.1
Végh, E.M.2
Csermely, P.3
Söti, C.4
-
107
-
-
60749101582
-
Stress-inducible regulation of heat shock factor 1 by the deacetylase SIRT1
-
Westerheide, S.D.; Anckar, J.; Stevens, S.M., Jr.; Sistonen, L.; Morimoto, R.I. Stress-inducible regulation of heat shock factor 1 by the deacetylase SIRT1. Science, 2009, 323(5917), 1063-1066.
-
(2009)
Science
, vol.323
, Issue.5917
, pp. 1063-1066
-
-
Westerheide, S.D.1
Anckar, J.2
Stevens Jr., S.M.3
Sistonen, L.4
Morimoto, R.I.5
|