The failure of dose-response models to predict low dose effects: A major challenge for biomedical, toxicological and aging research

Biogerontology

Volumn 7, Issue 2, 2006, Pages 119-122

  Calabrese, Edward J ^a  

^a UNIVERSITY OF MASSACHUSETTS   (United States)

Author keywords

Anti aging; Biogerontology; Biphasic; Dose response; History of science; Homeopathy; Hormesis; Risk assessment; Stress; Threshold

Indexed keywords

DRUG;

AGING; ARTICLE; BIOLOGICAL MODEL; BIOMEDICINE; BIOSTATISTICS; COMPARATIVE TOXICOLOGY; DOSE RESPONSE; DRUG MEGADOSE; DRUG SURVEILLANCE PROGRAM; GERONTOLOGICAL RESEARCH; HEALTH HAZARD; HISTORY OF MEDICINE; HOMEOPATHY; HORMESIS; INTERMETHOD COMPARISON; LOW DRUG DOSE; PHARMACOLOGICAL PARAMETERS; PREDICTION; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RISK ASSESSMENT;

AGING; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; HISTORY, 19TH CENTURY; HISTORY, 20TH CENTURY; HUMANS; MODELS, BIOLOGICAL; PHARMACOLOGY; PREDICTIVE VALUE OF TESTS; TOXICOLOGY;

EID: 33745469011     PISSN: 13895729     EISSN: 15736768     Source Type: Journal    
DOI: 10.1007/s10522-006-0005-z     Document Type: Article

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