Synaptic ultrastructural alterations anticipate the development of neuroaxonal dystrophy in sympathetic ganglia of aged and diabetic mice

Journal of Neuropathology and Experimental Neurology

Volumn 67, Issue 12, 2008, Pages 1166-1186

  Schmidt, Robert E ^a,c   Parvin, Curtis A ^b   Green, Karen G ^a  

^a Laboratory Medicine   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c WASHINGTON UNIVERSITY   (United States)

Author keywords

Aging; Autonomic neuropathy; Dendritic dystrophy; Diabetic neuropathy; Mitochondriopathy; Neuroaxonal dystrophy

Indexed keywords

AGED; AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN MITOCHONDRION; CELL AGGREGATION; CELL SIZE; CELL STRUCTURE; CELL SWELLING; CONTROLLED STUDY; DENDRITE; DISORDERS OF MITOCHONDRIAL FUNCTIONS; FEMALE; INSULIN DEPENDENT DIABETES MELLITUS; MALE; MOLECULAR DYNAMICS; MOUSE; NERVE ENDING; NEUROAXONAL DYSTROPHY; NONHUMAN; PHAGOSOME; PRESYNAPTIC NERVE; PRIORITY JOURNAL; SYMPATHETIC GANGLION; SYNAPSE; SYNAPSE VESICLE; ANIMAL; AUTONOMIC NEUROPATHY; C57BL MOUSE; DIABETIC NEUROPATHY; DISEASE MODEL; EXPERIMENTAL DIABETES MELLITUS; IMAGE CYTOMETRY; INTRACELLULAR MEMBRANE; MITOCHONDRION; MOUSE MUTANT; NERVE DEGENERATION; PATHOLOGY; SYNAPTIC MEMBRANE; SYNAPTOSOME; TRANSMISSION ELECTRON MICROSCOPY; ULTRASTRUCTURE;

AGING; ANIMALS; AUTONOMIC NERVOUS SYSTEM DISEASES; DENDRITES; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC NEUROPATHIES; DISEASE MODELS, ANIMAL; FEMALE; GANGLIA, SYMPATHETIC; IMAGE CYTOMETRY; INTRACELLULAR MEMBRANES; MALE; MICE; MICE, INBRED C57BL; MICE, MUTANT STRAINS; MICROSCOPY, ELECTRON, TRANSMISSION; MITOCHONDRIA; NERVE DEGENERATION; PHAGOSOMES; PRESYNAPTIC TERMINALS; SYNAPSES; SYNAPTIC MEMBRANES;

EID: 58149376487     PISSN: 00223069     EISSN: None     Source Type: Journal    
DOI: 10.1097/NEN.0b013e318190d6db     Document Type: Article

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