Mitochondrial organization and motility probed by two-photon microscopy in cultured mouse brainstem neurons

Experimental Cell Research

Volumn 303, Issue 1, 2005, Pages 114-127

  Müller, Michael ^a   Mironov, Sergej L ^a   Ivannikov, Maxim V ^a   Schmidt, Jörg ^a   Richter, Diethelm W ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

Author keywords

cAMP; Microfilaments; Microtubules; Mitochondrial interaction; Mitochondrial potential; Protein phosphorylation

Indexed keywords

CALYCULIN A; COLCHICINE; CYCLIC AMP; FORSKOLIN; ISOBUTYLMETHYLXANTHINE; NOCODAZOLE; RHODAMINE;

ANIMAL CELL; ARTICLE; BRAIN MITOCHONDRION; BRAIN STEM; CELL DISRUPTION; CELL INTERACTION; CELL MEMBRANE DEPOLARIZATION; CELL MOTILITY; CONTROLLED STUDY; CYTOSKELETON; CYTOSOL; DENDRITE; DEPOLYMERIZATION; ENZYME INHIBITION; FLUORESCENCE MICROSCOPY; IMMOBILIZED CELL; MICROTUBULE; MOLECULAR DYNAMICS; MOUSE; NERVE CELL CULTURE; NONHUMAN; PERIKARYON; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RESPIRATION CENTER;

EID: 9644290768     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yexcr.2004.09.025     Document Type: Article

References (52)

1. P. Mitchell Coupling of phosphorylation to electron and hydrogen transfer by a chemiosmotic type of mechanism Nature 191 1961 144 148
2. D.G. Nicholls The regulation of extramitochondrial free calcium ion concentration by rat liver mitochondria Biochem. J. 176 1978 463 474
3. M.R. Duchen Contributions of mitochondria to animal physiology: from homeostatic sensor to calcium signalling and cell death J. Physiol. (Lond.) 516 1999 1 17
4. D.G. Nicholls, and S.L. Budd Mitochondria and neuronal survival Physiol. Rev. 80 2000 315 360
5. A.H. Schapira, M. Gu, J.W. Taanman, S.J. Tabrizi, T. Seaton, M. Cleeter, and J.M. Cooper Mitochondria in the etiology and pathogenesis of Parkinson's disease Ann. Neurol. 44 1998 S89 S98
6. J. Kong, and Z. Xu Massive mitochondrial degeneration in motor neurons triggers the onset of amyotrophic lateral sclerosis in mice expressing a mutant SOD1 J. Neurosci. 18 1998 3241 3250
7. D.R. Green, and J.C. Reed Mitochondria and apoptosis Science 281 1998 1309 1312
8. A.A. Amchenkova, L.E. Bakeeva, Y.S. Chentsov, V.P. Skulachev, and D.B. Zorov Coupling membranes as energy-transmitting cables. I. Filamentous mitochondria in fibroblasts and mitochondrial clusters in cardiomyocytes J. Cell Biol. 107 1988 481 495
9. V.N. Dedov, and B.D. Roufogalis Organization of mitochondria in living sensory neurons FEBS Lett. 456 1999 171 174
10. V.P. Skulachev Mitochondrial filaments and clusters as intracellular power-transmitting cables Trends Biochem. Sci. 26 2001 23 29
11. M.R. Lewis, and W.H. Lewis Mitochondria (and other cytoplasmic structures) in tissue cultures Am. J. Anat. 17 1914 339 401
12. L.E. Bakeeva, Y.S. Chentsov, and V.P. Skulachev Mitochondrial framework (reticulum mitochondriale) in rat diaphragm muscle Biochim. Biophys. Acta 501 1978 349 369
13. T.J. Collins, M.J. Berridge, P. Lipp, and M.D. Bootman Mitochondria are morphologically and functionally heterogenous within cells EMBO J. 21 2002 1616 1627
14. L.A. Ligon, and O. Steward Movement of mitochondria in the axons and dendrites of cultured hippocampal neurons J. Comp. Neurol. 427 2002 340 350
15. G.L. Rintoul, A.J. Filiano, J.B. Brocard, G.J. Kress, and I.J. Reynolds Glutamate decreases mitochondrial size and movement in primary forebrain neurons J. Neurosci. 23 2003 7881 7888
16. 2+ release: an intimate connection Trends Biochem. Sci. 25 2000 215 221
17. V.N. Dedov, G.C. Cox, and B.D. Roufogalis Visualisation of mitochondria in living neurons with single- and two-photon fluorescence laser microscopy Micron 32 2001 653 660
18. M. Müller, S.L. Mironov, J. Schmidt, and D.W. Richter Mitochondrial organization and motility probed by twin-photon microscopy in cultured murine brainstem neurons FASEB J. 16 2002 A464 [Abstracts]
19. M. Müller, S.L. Mironov, J. Schmidt, and D.W. Richter Mitochondrial organization and motility in neurons depends on microtubule integrity and the status of protein phosphorylation Soc. Neurosci. Abstr. 2002 742.11
20. M. Müller, S.L. Mironov, J. Schmidt, and D.W. Richter Mitochondrial network organization and motility in mouse respiratory neurons Eur. J. Physiol. 445 Suppl. 1 2003 [P 04-2]
21. R.K. Emaus, R. Grunwald, and J.J. Lemasters Rhodamine 123 as a probe of transmembrane potential in isolated rat-liver mitochondria: spectral and metabolic properties Biochim. Biophys. Acta 850 1986 436 448
22. M. Müller, J. Schmidt, S.L. Mironov, and D.W. Richter Construction and performance of a custom-built two-photon laser scanning system J. Phys. D: Appl. Phys. 36 2003 1747 1757
23. J.F. Buckman, and I.J. Reynolds Spontaneous changes in mitochondrial membrane potential in cultured neurons J. Neurosci. 21 2001 5054 5065
24. S.L. Mironov, and D.W. Richter Oscillations and hypoxic changes of mitochondrial variables in neurons of the brainstem respiratory centre of mice J. Physiol. (Lond.) 533 2001 227 236
25. O. Vergun, T.V. Votyakova, and I.J. Reynolds Spontaneous changes in mitochondrial membrane potential in single isolated brain mitochondria Biophys. J. 85 2003 3358 3366
26. J. Bereiter-Hahn Behavior of mitochondria in the living cell Int. Rev. Cytol. 122 1990 1 63
27. E.K. Rowinsky, L.A. Cazenave, and R.C. Donehower Taxol: a novel investigational antimicrotubule agent J. Natl. Cancer Inst. 82 1990 1247 1259
28. K.D. Lee, and P.J. Hollenbeck Phosphorylation of kinesin in vivo correlates with organelle association and neurite outgrowth J. Biol. Chem. 270 1995 5600 5605
29. R. Sato-Yoshitake, H. Yorifuji, M. Inagaki, and N. Hirokawa The phosphorylation of kinesin regulates its binding to synaptic vesicles J. Biol. Chem. 267 1992 23930 23936
30. C. Bialojan, and A. Takai Inhibitory effect of a marine-sponge toxin, okadaic acid, on protein phosphatases Biochem. J. 256 1988 283 290
31. A.H. Walsh, A. Cheng, and R.E. Honkanen Fostriecin, an antitumor antibiotic with inhibitory activity against serine/threonine protein phosphatases types 1 (PP1) and 2A (PP2A), is highly selective for PP2A FEBS Lett. 416 1997 230 234
32. E.H. Ball, and S.J. Singer Mitochondria are associated with microtubules and not with intermediate filaments in cultured fibroblasts Proc. Natl. Acad. Sci. U. S. A. 79 1982 123 126
33. A. Egner, S. Jakobs, and S.W. Hell Fast 100-nm resolution three-dimensional microscope reveals structural plasticity of mitochondria in live yeast Proc. Natl. Acad. Sci. U. S. A. 99 2002 3370 3375
34. K.G. Hales, and M.T. Fuller Developmentally regulated mitochondrial fusion mediated by a conserved, novel, predicted GTPase Cell 90 1997 121 129
35. M.P. Yaffe The cutting edge of mitochondrial fusion Nat. Cell Biol. 5 2003 497 499
36. S. Meeusen, J.M. McCaffery, and J. Nunnari Mitochondrial fusion intermediates revealed in vitro Science 305 2004 1747 1752
37. H. Sesaki, and R.E. Jensen Ugo1p links the Fzo1p and Mgm1p GTPases for mitochondrial fusion J. Biol. Chem. 279 2004 28298 28303
38. Y. Mattenberger, D.I. James, and J.-C. Martinou Fusion of mitochondria in mammalian cells is dependent on the mitochondrial inner membrane potential and independent of microtubules or actin FEBS Lett. 538 2003 53 59
39. L.A. Ligon, and O. Steward Role of microtubules and actin filaments in the movement of mitochondria in the axons and dendrites of cultured hippocampal neurons J. Comp. Neurol. 427 2000 351 361
40. M.H. Heggeness, M. Simon, and S.J. Singer Association of mitochondria with microtubules in cultured cells Proc. Natl. Acad. Sci. U. S. A. 75 1978 3863 3866
41. J.F. Leterrier, D.A. Rusakov, B.D. Nelson, and M. Linden Interactions between brain mitochondria and cytoskeleton: evidence for specialized outer membrane domains involved in the association of cytoskeleton-associated proteins to mitochondria in situ and in vitro Microsc. Res. Tech. 27 1994 233 261
42. R.L. Morris, and P.J. Hollenbeck Axonal transport of mitochondria along microtubules and F-actin in living vertebrate neurons J. Cell Biol. 131 1995 1315 1326
43. D. Margineantu, R.A. Capaldi, and A.H. Marcus Dynamics of the mitochondrial reticulum in live cells using Fourier imaging correlation spectroscopy and digital video microscopy Biophys. J. 79 2000 1833 1849
44. R.D. Vale, and R.J. Fletterick The design plan of kinesin motors Annu. Rev. Cell Dev. Biol. 13 1997 745 777
45. S. Brady, and R. Lasek Axonal transport: a cell-biological method for studying proteins that associate with the cytoskeleton Methods Cell Biol. 25 1982 365 398
46. K. De Vos, F. Severin, F. Van Herreweghe, K. Vancompernolle, V. Goossens, A. Hyman, and J. Grooten Tumor necrosis factor induces hyperphosphorylation of kinesin light chain and inhibits kinesin-mediated transport of mitochondria J. Cell Biol. 149 2000 1207 1214
47. F. Ichas, L.S. Jouaville, and J.P. Mazat Mitochondria are excitable organelles capable of generating and conveying electrical and calcium signals Cell 89 1997 1145 1153
48. R.K. Orkand, J.G. Nicholls, and S.W. Kuffler Effects of nerve impulses on the membrane potential of glial cells in the central nervous system of amphibia J. Neurophysiol. 29 1966 788 806
49. L.S. Jouaville, F. Ichas, E.L. Holmuhamedov, P. Camacho, and J.D. Lechleiter Synchronization of calcium waves by mitochondrial substrates in Xenopus laevis oocytes Nature 377 1995 438 441
50. G. Csordás, A.P. Thomas, and G. Hajnóczky Quasi-synaptic calcium, signal transmission between endoplasmic reticulum and mitochondria EMBO J. 18 1999 96 108
51. A. Boveris, and B. Chance The mitochondrial generation of hydrogen peroxide. General properties and effect of hyperbaric oxygen Biochem. J. 134 1973 707 716
52. W. Dröge Free radicals in the physiological control of cell function Physiol. Rev. 82 2002 47 95