Uncoupling proteasome peptidase and ATPase activities results in cytosolic release of an ER polytopic protein

Journal of Cell Science

Volumn 119, Issue 2, 2006, Pages 303-313

  Oberdorf, Jon ^a,b   Carlson, Eric J ^a   Skach, William R ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b PORTLAND VA MEDICAL CENTER   (United States)

Author keywords

CFTR; Cystic fibrosis; ER dislocation; ER associated degradation; p97; Polytopic proteins; Proteasome inhibitors

Indexed keywords

ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATE; PEPTIDASE; PROTEASOME; PROTEASOME INHIBITOR; TRANSMEMBRANE CONDUCTANCE REGULATOR; TRICHLOROACETIC ACID; UNCOUPLING PROTEIN;

ANIMAL CELL; ARTICLE; BETA CHAIN; CELL MEMBRANE; CONTROLLED STUDY; CORRELATION FUNCTION; CYTOSOL; ENDOPLASMIC RETICULUM; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME INHIBITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN SECRETION;

ADENOSINE TRIPHOSPHATASES; ADENOSINE TRIPHOSPHATE; ANIMALS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; ENDOPLASMIC RETICULUM; HEMIN; HUMANS; PEPTIDE FRAGMENTS; PEPTIDE HYDROLASES; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN SUBUNITS; TRICHLOROACETIC ACID; TUMOR NECROSIS FACTOR RECEPTOR-ASSOCIATED PEPTIDES AND PROTEINS;

ANIMALIA;

EID: 32244432065     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.02732     Document Type: Article

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