Rationale for hypertonic saline therapy for cystic fibrosis lung disease

Seminars in Respiratory and Critical Care Medicine

Volumn 28, Issue 3, 2007, Pages 295-302

  Tarran, Robert ^a   Donaldson, Scott ^a   Boucher, Richard C ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

Cystic fibrosis; Cystic fibrosis transmembrane conductance regulator (CFTCR) gene; Hypertonic saline; Osmotic gradient; Sodium and calcium channel

Indexed keywords

AMILORIDE; CHLORIDE CHANNEL; SODIUM CHLORIDE; TRANSMEMBRANE CONDUCTANCE REGULATOR;

CHLORIDE TRANSPORT; CYSTIC FIBROSIS; GENE MUTATION; HUMAN; LUNG DISEASE; LUNG FUNCTION; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; QUALITY OF LIFE; REHYDRATION; RESPIRATORY EPITHELIUM; REVIEW; SODIUM TRANSPORT;

ADMINISTRATION, INHALATION; AEROSOLS; BIOLOGICAL TRANSPORT, ACTIVE; CELL MEMBRANE PERMEABILITY; CYSTIC FIBROSIS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; EPITHELIAL SODIUM CHANNEL; HUMANS; MODELS, BIOLOGICAL; MUCOCILIARY CLEARANCE; RESPIRATORY MUCOSA; SALINE SOLUTION, HYPERTONIC;

EID: 34250887562     PISSN: 10693424     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2007-981650     Document Type: Review

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