High-performance liquid chromatography electrospray ionization tandem mass spectrometry for the detection and quantitation of pyrrolizidine alkaloid-derived DNA adducts in vitro and in viwo

Chemical Research in Toxicology

Volumn 23, Issue 3, 2010, Pages 637-652

  Fu, Peter P ^a   Chou, Ming W ^a   Churchwell, Mona ^a   Wang, Yuping ^a   Zhao, Yuewei ^a   Xia, Qingsu ^a   Da Costa, Gonçalo Gamboa ^a   Marques, M Matilde ^b   Beland, Frederick A ^a   Doerge, Daniel R ^a  

^a NATIONAL CENTER FOR TOXICOLOGICAL RESEARCH   (United States)

^b INSTITUTO SUPERIOR TÉCNICO   (Portugal)

Author keywords

[No Author keywords available]

Indexed keywords

6,7 DIHYDRO 7 HYDROXY 1 HYDROXYMETHYL 5H PYRROLIZINE; DEOXYADENOSINE; DEOXYGUANOSINE; MONOCROTALINE; PHOSPHORUS 32; PYRROLIZIDINE ALKALOID; PYRROLIZINE DERIVATIVE; RIDDELLINE; UNCLASSIFIED DRUG;

ACCURACY; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CARCINOGENESIS; CHEMICAL ANALYSIS; CHEMICAL REACTION; DNA ADDUCT; ELECTROSPRAY MASS SPECTROMETRY; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIVER; NONHUMAN; QUANTITATIVE ANALYSIS; RAT; SENSITIVITY AND SPECIFICITY;

ANIMALS; CALIBRATION; CATTLE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DNA; DNA ADDUCTS; FEMALE; LIVER; PYRROLIZIDINE ALKALOIDS; RATS; RATS, INBRED F344; SENSITIVITY AND SPECIFICITY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TANDEM MASS SPECTROMETRY;

RATTUS;

EID: 77949361456     PISSN: 0893228X     EISSN: 15205010     Source Type: Journal    
DOI: 10.1021/tx900402x     Document Type: Article

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