Genotoxic pyrrolizidine alkaloids and pyrrolizidine alkaloid N-oxides - Mechanisms leading to DNA adduct formation and tumorigenicity

Journal of Environmental Science and Health - Part C Environmental Carcinogenesis and Ecotoxicology Reviews

Volumn 19, Issue 2, 2001, Pages 353-385

  Fu, P P ^a   Chou, M W ^a   Xia, Q ^a   Yang, Y C ^a   Yan, J ^a   Doerge, D R ^a   Chan, P C ^b  

^a NATIONAL CENTER FOR TOXICOLOGICAL RESEARCH   (United States)

^b NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

DNA adducts; Human exposure; Mechanism; Pyrrolizidine alkaloids; Tumorigenicity

Indexed keywords

AGRICULTURE; BIOMARKERS; PLANTS (BOTANY); TUMORS;

ALKALOIDS;

DNA;

ALKALOID DERIVATIVE; BIOLOGICAL MARKER; DEHYDRORETRONECINE; OXIDE; PYRROLIZIDINE ALKALOID; RIDDELLIINE N OXIDE; RIDDELLINE; UNCLASSIFIED DRUG;

ARTICLE; CARCINOGENESIS; CARCINOGENICITY; DNA ADDUCT; ENVIRONMENTAL EXPOSURE; GENOTOXICITY; MUTAGENICITY; NONHUMAN; PLANT; TERATOGENICITY;

ANIMALIA;

EID: 0035206839     PISSN: 10590501     EISSN: None     Source Type: Journal    
DOI: 10.1081/GNC-100107580     Document Type: Article

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