IL-1: Discoveries, controversies and future directions

European Journal of Immunology

Volumn 40, Issue 3, 2010, Pages 599-606

  Dinarello, Charles A ^a,b  

^a UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Cytokines; Immunotherapy; Innate immunity; TLR

Indexed keywords

CATABOLIN; COMPLEMENTARY DNA; CRYOPYRIN; CYTOKINE; ENDOTOXIN; INFLAMMASOME; INTERLEUKIN 1; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; INTERLEUKIN 2; PROTEIN; PYREXIN; PYROGEN; RECOMBINANT INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; RECOMBINANT INTERLEUKIN 1BETA; RECOMBINANT PROTEIN; TOLL LIKE RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; BONE MARROW TRANSPLANTATION; CLONING; CYTOKINE PRODUCTION; GOUT; HEART INFARCTION; HISTORY OF MEDICINE; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNITY; IMMUNOTHERAPY; INFLAMMATION; INNATE IMMUNITY; JUVENILE RHEUMATOID ARTHRITIS; LEUKOCYTE; MOUSE; MULTIPLE MYELOMA; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PERITONITIS; PRIORITY JOURNAL; RABBIT; REVIEW; RHEUMATOID ARTHRITIS; SEPSIS; STAPHYLOCOCCUS EPIDERMIDIS;

ANIMALS; HISTORY, 20TH CENTURY; HISTORY, 21ST CENTURY; HUMANS; INFLAMMATION; INTERLEUKIN-1;

EID: 77749304035     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201040319     Document Type: Review

References (117)

1. Atkins, E., J. Infect. Dis. 1984. 149: 339-348.
2. Beeson, P. B., J. Clin. Invest. 1948. 27: 524 (abstract).
3. Dinarello, C. A. et al., Proc. Natl. Acad. Sci. USA 1977. 74: 4624-4627.
4. Auron, P. E. et al., Proc. Natl. Acad. Sci. USA 1984. 81: 7907-7911.
5. Ogilvie, A. C. et al., J. Immunol. 1996. 156: 389-394.
6. Tewari, A. et al., Lancet 1990. 336: 712-714.
7. Atkins, E. and Wood Jr, W. B., J. Exp. Med. 1955. 101: 519-528.
8. Murphy, P. A. et al., J. Lab. Clin. Med. 1974. 83: 310-322.
9. Bodel, P. and Atkins, E., N. Engl. J. Med. 1967. 276: 1002-1008.
10. Bodel, P. et al., J. Clin. Invest. 1980. 65: 514-518.
11. Gery, I. and Waksman, B. H., J. Exp. Med. 1972. 136: 143-155.
12. Mier, J. W. and Gallo, R. C., Proc. Natl. Acad. Sci. USA 1980. 77: 6134-6138.
13. Aarden, L., J. Immunol. 1979. 123: 2928-2929.
14. Rosenwasser, L. J. et al., J. Exp. Med. 1979. 150: 709-714.
15. Merriman, C. R. et al., Proc. Soc. Exp. Biol. Med. 1977. 154: 224-227.
16. Dinarello, C. A., N. Engl. J. Med. 1984. 311: 1413-1418.
17. Damais, C. et al., Int. J. Immunopharmacol. 1982. 4: 451-462.
18. Dinarello, C. A. et al., J. Exp. Med. 1974. 139: 1369-1381.
19. Lomedico, P. T. et al., Nature 1984. 312: 458-462.
20. Bendtzen, K. et al., Science 1986. 232: 1545-1547.
21. Okusawa, S. et al., J. Clin. Invest. 1988. 81: 1162-1172.
22. Smith, J. W. et al., N. Engl. J. Med. 1993. 328: 756-761.
23. Sims, J. E. et al., Science 1988. 241: 585-589.
24. Gay, N. J. and Keith, F. J., Nature 1991. 351: 355-356.
25. Ulevitch, R. J. and Tobias, P. S., Curr. Opin. Immunol. 1994. 6: 125-130.
26. Heguy, A. et al., J. Biol. Chem. 1992. 267: 2605-2609.
27. Poltorak, A. et al., Science 1998. 282: 2085-2088.
28. Kirschning, C. J. et al., J. Exp. Med. 1998. 188: 2091-2097.
29. Yang, R. B. et al., Nature 1998. 395: 284-288.
30. O'Neill, L. A., Immunol. Rev. 2008. 226: 10-18.
31. Iwasaki, A. and Medzhitov, R., Science. 2010. 327: 291-295.
32. Lemaitre, B. et al., Cell 1996. 86: 973-983.
33. van der Meer, J. W. M. et al., Proc. Natl. Acad. Sci. USA 1988. 85: 1620-1623.
34. Fleischmann, R. M. et al., Ann. Rheum. Dis. 2006. 65: 1006-1012.
35. Werman, A. et al., Proc. Natl. Acad. Sci. USA 2004. 101: 2434-2439.
36. Chen, C. J. et al., Nat. Med. 2007. 13: 851-856.
37. Cohen, I. et al., Proc. Natl. Acad. Sci. USA 2010. 107: 2574-2579.
38. Carriere, V. et al., Proc. Natl. Acad. Sci. USA 2007. 104: 282-287.
39. Cayrol, C. and Girard, J. P., Proc. Natl. Acad. Sci. USA 2009. 106: 9021-9026.
40. Beck, G. and Habicht, G. S., Proc. Natl. Acad. Sci. USA 1986. 83: 7429-7433.
41. Martinon, F. and Tschopp, J., Cell Death Differ. 2007. 14: 10-22.
42. Dinarello, C. A., Annu. Rev. Immunol. 2009. 27: 519-550.
43. Fantuzzi, G. et al., J. Immunol. 1997. 158: 1818-1824.
44. Coeshott, C. et al., Proc. Natl. Acad. Sci. USA 1999. 96: 6261-6266.
45. Joosten, L. A. et al., Arthritis Rheum. 2009. 60: 3651-3662.
46. Dinarello, C. A. et al., J. Immunol. 1987. 139: 1902-1910.
47. Goldbach-Mansky, R. et al., N. Engl. J. Med. 2006. 355: 581-592.
48. Netea, M. G. et al., Blood 2009. 113: 2324-2335.
49. Okamoto, M. et al., J. Biol. Chem. 2009.
50. Dostert, C. et al., Science 2008. 320: 674-677.
51. Martinon, F., Eur. J. Immunol. 2010. 616-619.
52. Meissner, F. et al., Nat. Immunol. 2008. 9: 866-872.
53. Tassi, S. et al., J. Immunol. 2009. 183: 1456-1462.
54. Hornung, V. et al., Nat. Immunol. 2008. 9: 847-856.
55. van de Veerdonk, F. L. et al., Proc. Natl. Acad. Sci. USA 2010. in press.
56. Nowak, R., Science 1994. 264: 500-501.
57. Bruckdorfer, K. R., Proc. Nutr. Soc. 2008. 67: 214-222.
58. Evans, J., Eye (Lond) 2008. 22: 751-760.
59. Cook, G. P. et al., Eur. J. Immunol. 2010. 631-634.
60. Abbate, A. et al., Am. J. Cardiol. 2010. in press.
61. Larsen, C. M. et al., N. Engl. J. Med. 2007. 356: 1517-1526.
62. Donath, M. Y. et al., Diabetes 2009. 58: A30.
63. Larsen, C. M. et al., Diabetes Care 2009. 32: 1663-1668.
64. Abbate, A. et al., Circulation 2008. 117: 2670-2683.
65. Boni-Schnetzler, M. et al., J. Clin. Endocrinol. Metab. 2008. 93: 4065-4074.
66. Maedler, K. et al., J. Clin. Invest. 2002. 110: 851-860.
67. Krelin, Y. et al., Cancer Res. 2007. 67: 1062-1071.
68. Lust, J. A. et al., Mayo Clin. Proc. 2009. 84: 114-122.
69. Carmi, Y. et al., J. Immunol. 2009. 183: 4705-4714.
70. Sutton, C. et al., J. Exp. Med. 2006. 203: 1685-1691.
71. Cho, M. L. et al., J. Immunol. 2006. 176: 5652-5661.
72. Nakae, S. et al., Proc. Natl. Acad. Sci. USA 2003. 100: 5986-5990.
73. Koenders, M. I. et al., Arthritis Rheum. 2008. 58: 3461-3470.
74. Matsuki, T. et al., Int. Immunol. 2006. 18: 399-407.
75. Chizzolini, C. et al., Blood 2008. 112: 3696-3703.
76. van de Veerdonk, F. L. et al., J. Leuk. Biol. 2010. in press.
77. Schmitz, J. et al., Immunity 2005. 23: 479-490.
78. Verri Jr, W. A. et al., Proc. Natl. Acad. Sci. USA 2008. 105: 2723-2728.
79. Yin, H. et al., Biochem. Biophys. Res. Commun. 2006. 351: 940-946.
80. Blumberg, H. et al., J. Exp. Med. 2007. 204: 2603-2614.
81. Boraschi, D. and Dinarello, C. A., Eur. Cytokine Netw. 2006. 17: 224-252.
82. Novick, D. et al., Immunity 1999. 10: 127-136.
83. Tak, P. P. et al., Eur. J. Drug Metab. Pharmacokinet. 2006. 31: 109-116.
84. Mazodier, K. et al., Blood 2005. 106: 3483-3489.
85. Parikh, C. R. et al., J. Am. Soc. Nephrol. 2010. in press.
86. Sharma, S. et al., J. Immunol. 2008. 180: 5477-5482.
87. Pan, G. et al., Cytokine 2001. 13: 1-7.
88. Kumar, S. et al., Cytokine 2002. 18: 61-71.
89. Bernheim, H. A. and Kluger, M. J., Am. J. Physiol. 1976. 231: 198-203.
90. Murphy, P. A. et al., Ciba Found. Symp. 1971. 59-79.
91. Kampschmidt, R. F. et al., Am. J Physiol. 1973. 224: 530-533.
92. Dayer, J. M. et al., Science 1977. 195: 181-183.
93. Saklatvala, J. and Dingle, J. T., Biochem. Biophys. Res. Commun. 1980. 96: 1225-1231.
94. Dinarello, C. A. et al., J. Immunol. 1981. 127: 2517-2519.
95. Seckinger, P. et al., J. Immunol. 1987. 139: 1546-1549.
96. Eisenberg, S. P. et al., Nature 1990. 343: 341-346.
97. Spriggs, M. K. et al., J. Biol. Chem. 1990. 265: 22499-22505.
98. Greenfeder, S. A. et al., J. Biol. Chem. 1995. 270: 13757-13765.
99. Thornberry, N. A. et al., Nature 1992. 356: 768-774.
100. Taguchi, T. et al., Genomics. 32: 486-488.
101. Medzhitov, R. et al., Nature. 388: 394-397.
102. Hoffman, H. M. et al., Nat. Genet. 2001. 29: 301-305.
103. Agostini, L. et al., Immunity 2004. 20: 319-325.
104. Dinarello, C. A. et al., Blood 1996. 87: 2095-2147.
105. Granowitz, E. V. et al., Cytokine 1992. 4: 353-360.
106. Lebsack, M. E. et al., Arthr. Rheumat. 1993. 36: S39.
107. Opal, S. M. et al., Crit. Care Med. 1997. 25: 1115-1124.
108. Fisher, C. J. J. et al., JAMA 1994. 271: 530-533.
109. Fisher, C. J. J. et al., Crit. Care Med. 1994. 22: 12-21.
110. Bresnihan, B. et al., Arthritis Rheum. 1998. 41: 2196-2204.
111. Hawkins, P. N. et al., N. Engl. J. Med. 2003. 2583: 2584-533.
112. Simon, A. and van der Meer, J. W., Am. J. Physiol. Regul. Integr. Comp. Physiol. 2007. 292: R86-98.
113. Masters, S. L. et al., Annu. Rev. Immunol. 2009. 27: 621-668.
114. Pascual, V. et al., J. Exp. Med. 2005. 201: 1479-1486.
115. Fitzgerald, A. A. et al., Arthritis Rheum. 2005. 52: 1794-1803.
116. So, A. et al., Arthritis Res. Ther. 2007. 9: R28.
117. Lachmann, H. et al., N. Engl. J. Med. 2009. 360: 2416-2425.