Pharmacokinetics of IL-18 binding protein in healthy volunteers and subjects with rheumatoid arthritis or plaque psoriasis

European Journal of Drug Metabolism and Pharmacokinetics

Volumn 31, Issue 2, 2006, Pages 109-116

  Tak, Paul P ^a   Bacchi, Marisa ^b   Bertolino, Mauro ^b   Desson, Andrew ^b  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b Serono International SA   (Switzerland)

Author keywords

IL 18 binding protein; Pharmacokinetics; Psoriasis; Rheumatoid arthritis

Indexed keywords

DISEASE MODIFYING ANTIRHEUMATIC DRUG; DOXYCYCLINE; INTERLEUKIN 18 BINDING PROTEIN; PLACEBO; RECOMBINANT PROTEIN;

ABNORMALLY LOW SUBSTRATE CONCENTRATION IN BLOOD; ADULT; AGED; ANXIETY; AREA UNDER THE CURVE; ARTICLE; BREAST DISEASE; BRONCHOPNEUMONIA; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE SEVERITY; DIZZINESS; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; DRUG BLOOD LEVEL; DRUG ERUPTION; DRUG HALF LIFE; DRUG MECHANISM; DRUG SAFETY; DRUG TOLERABILITY; DRUG URINE LEVEL; DYSPNEA; EOSINOPHILIA; FEMALE; GASTROINTESTINAL DISEASE; HEADACHE; HUMAN; HUMAN EXPERIMENT; INFECTION; INFESTATION; INJECTION SITE ERYTHEMA; INJECTION SITE PAIN; INJECTION SITE PRURITUS; INJECTION SITE REACTION; LARYNX PAIN; LYMPHOCYTE COUNT; LYMPHOCYTOPENIA; LYMPHOCYTOSIS; MAJOR CLINICAL STUDY; MALE; MASTALGIA; MEDIASTINUM DISEASE; NAUSEA; NORMAL HUMAN; PHASE 1 CLINICAL TRIAL; PRURITUS; PSORIASIS VULGARIS; RANDOMIZED CONTROLLED TRIAL; RESPIRATORY TRACT DISEASE; RHEUMATOID ARTHRITIS; RHINOPHARYNGITIS; SIDE EFFECT; SKIN DISEASE; SORE THROAT; STEADY STATE; THORAX DISEASE; UNSPECIFIED SIDE EFFECT;

EID: 33746687953     PISSN: 03787966     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF03191127     Document Type: Article

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