Proximity effects in nucleophilic addition reactions to medium-bridged twisted lactams: Remarkably stable tetrahedral intermediates

Journal of the American Chemical Society

Volumn 132, Issue 6, 2010, Pages 2078-2084

  Szostak, Michal ^a   Yao, Lei ^a   Aubé, Jeffrey ^a  

^a UNIVERSITY OF KANSAS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

[CARBONYL; AMIDE BOND; CARBOXYLIC ACID DERIVATIVES; NUCLEOPHILIC ADDITIONS; ORGANOMETALLIC REAGENT; PROXIMITY EFFECTS; TETRAHEDRAL INTERMEDIATES; TWISTED AMIDES;

ADDITION REACTIONS; CARBOXYLIC ACIDS; KETONES; ORGANIC ACIDS; ORGANOMETALLICS; REACTION INTERMEDIATES;

AMIDES;

AMIDE; AMINOKETONE; CARBOXYLIC ACID DERIVATIVE; LACTAM DERIVATIVE; NUCLEOPHILE; ORGANOMETALLIC COMPOUND;

ADDITION REACTION; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMICAL INTERACTION; CHEMICAL REACTION; CHEMICAL STRUCTURE; INFRARED SPECTROSCOPY; SYNTHESIS;

AMIDES; CARBON; KETONES; LACTAMS; MOLECULAR CONFORMATION; NITROGEN; OXYGEN; ROTATION; SPECTROPHOTOMETRY, ULTRAVIOLET; STEREOISOMERISM;

EID: 77249177555     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja909792h     Document Type: Article

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