메뉴 건너뛰기




Volumn 117, Issue 15, 2004, Pages 3379-3388

CD9-mediated activation of the p46 Shc isoform leads to apoptosis in cancer cells

Author keywords

Apoptosis; Cancer cells; CD9; Shc; Tetraspanin

Indexed keywords

CASPASE 3; CD9 ANTIGEN; ISOPROTEIN; LIPOCORTIN 5; MITOGEN ACTIVATED PROTEIN KINASE P38; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY ALB6; PROTEIN P46; PROTEIN SHC; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

EID: 4344659148     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.01201     Document Type: Review
Times cited : (50)

References (51)
  • 1
    • 0033556356 scopus 로고    scopus 로고
    • A role for MAPK/ERK in sympathetic neuron survival: Protection against a p53-dependent, JNK-independent induction of apoptosis by cytosine arabinoside
    • Anderson, C. N. G. and Tolkovsky, A. M. (1999). A role for MAPK/ERK in sympathetic neuron survival: protection against a p53-dependent, JNK-independent induction of apoptosis by cytosine arabinoside. J. Neurosci. 19, 664-673.
    • (1999) J. Neurosci. , vol.19 , pp. 664-673
    • Anderson, C.N.G.1    Tolkovsky, A.M.2
  • 3
    • 0032428331 scopus 로고    scopus 로고
    • Modulation of life and death by the TNF receptor superfamily
    • Baker, S. J. and Reddy, E. P. (1998). Modulation of life and death by the TNF receptor superfamily. Oncogene 17, 3261-3270.
    • (1998) Oncogene , vol.17 , pp. 3261-3270
    • Baker, S.J.1    Reddy, E.P.2
  • 4
    • 0033950479 scopus 로고    scopus 로고
    • The tetraspanin CD9 associates with the integrin alpha6beta4 in cultured human epidermal keratinocytes and is involved in cell motility
    • Baudoux, B., Castanares-Zapatero, D., Leclercq-Smekens, M., Berna, N. and Poumay, Y. (2000). The tetraspanin CD9 associates with the integrin alpha6beta4 in cultured human epidermal keratinocytes and is involved in cell motility. Eur. J. Cell Biol. 79, 41-51.
    • (2000) Eur. J. Cell Biol. , vol.79 , pp. 41-51
    • Baudoux, B.1    Castanares-Zapatero, D.2    Leclercq-Smekens, M.3    Berna, N.4    Poumay, Y.5
  • 5
    • 0035207920 scopus 로고    scopus 로고
    • Complexes of tetraspanins with integrins: More than meets the eye
    • Berditchevski, F. (2001). Complexes of tetraspanins with integrins: more than meets the eye. J. Cell Sci. 114, 4143-4151.
    • (2001) J. Cell Sci. , vol.114 , pp. 4143-4151
    • Berditchevski, F.1
  • 6
    • 0033606802 scopus 로고    scopus 로고
    • Characterization of integrin-tetraspanin adhesion complexes: Role of tetraspanins in integrin signaling
    • Berditchevski, F. and Odintsova, E. (1999). Characterization of integrin-tetraspanin adhesion complexes: role of tetraspanins in integrin signaling. J. Cell Biol. 146, 477-492.
    • (1999) J. Cell Biol. , vol.146 , pp. 477-492
    • Berditchevski, F.1    Odintsova, E.2
  • 7
    • 0030062129 scopus 로고    scopus 로고
    • Characterization of novel complexes on the cell surface between integrins and proteins with 4 transmembrane domains (TM4 proteins)
    • Berditchevski, F., Zutter, M. M, and Hemler, M. E. (1996). Characterization of novel complexes on the cell surface between integrins and proteins with 4 transmembrane domains (TM4 proteins). Mol. Biol. Cell 7, 193-207.
    • (1996) Mol. Biol. Cell , vol.7 , pp. 193-207
    • Berditchevski, F.1    Zutter, M.M.2    Hemler, M.E.3
  • 9
    • 0020609758 scopus 로고
    • Characterization of platelet aggregation induced by the monoclonal antibody ALB6 (acute lymphoblastic leukemia antigen p24). Inhibition of aggregation by ALB6 Fab
    • Boucheix, C., Soria, C., Mirshahi, M., Soria, J., Perrot, J. Y., Fournier, N., Billard, M. and Rosenfeld, C. (1983). Characterization of platelet aggregation induced by the monoclonal antibody ALB6 (acute lymphoblastic leukemia antigen p24). Inhibition of aggregation by ALB6 Fab. FEBS Lett. 16, 289-295.
    • (1983) FEBS Lett. , vol.16 , pp. 289-295
    • Boucheix, C.1    Soria, C.2    Mirshahi, M.3    Soria, J.4    Perrot, J.Y.5    Fournier, N.6    Billard, M.7    Rosenfeld, C.8
  • 11
    • 0030834148 scopus 로고    scopus 로고
    • Differential display cloning identifies motility-related protein (MRP1/CD9) as highly expressed in primary compared to metastatic human colon carcinoma cells
    • Cajot, J. F., Sordat, I., Silvestre, T. and Sordat, B. (1997). Differential display cloning identifies motility-related protein (MRP1/CD9) as highly expressed in primary compared to metastatic human colon carcinoma cells. Cancer Res. 57, 2593-2597.
    • (1997) Cancer Res. , vol.57 , pp. 2593-2597
    • Cajot, J.F.1    Sordat, I.2    Silvestre, T.3    Sordat, B.4
  • 12
    • 0028329953 scopus 로고
    • JNK1: A protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain
    • Derijard, B., Hibi, M., Wu, I. H., Barrett, T., Su, B., Deng, T., Karin, M. and Davis, R. J. (1994). JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain. Cell 76, 1025-1037.
    • (1994) Cell , vol.76 , pp. 1025-1037
    • Derijard, B.1    Hibi, M.2    Wu, I.H.3    Barrett, T.4    Su, B.5    Deng, T.6    Karin, M.7    Davis, R.J.8
  • 13
    • 0032793067 scopus 로고    scopus 로고
    • B-Raf inhibits programmed cell death downstream of cytochrome c release from mitochondria by activating the MEK/Erk pathway
    • Erhardt, P., Schremser, E. J. and Cooper, G. M. (1999). B-Raf inhibits programmed cell death downstream of cytochrome c release from mitochondria by activating the MEK/Erk pathway. Mol. Cell. Biol. 19, 5308-5315.
    • (1999) Mol. Cell Biol. , vol.19 , pp. 5308-5315
    • Erhardt, P.1    Schremser, E.J.2    Cooper, G.M.3
  • 14
    • 0030899807 scopus 로고    scopus 로고
    • Tyrosine phosphorylation sites at amino acid 239 and 240 of Shc are involved in epidermal growth factor-induced mitogenic signaling that is distinct from Ras/mitogen-activated protein kinase activation
    • Gotoh, N., Toyoda, M. and Shibuya, M. (1997). Tyrosine phosphorylation sites at amino acid 239 and 240 of Shc are involved in epidermal growth factor-induced mitogenic signaling that is distinct from Ras/mitogen-activated protein kinase activation. Mol. Cell. Biol. 17, 1824-1831.
    • (1997) Mol. Cell Biol. , vol.17 , pp. 1824-1831
    • Gotoh, N.1    Toyoda, M.2    Shibuya, M.3
  • 15
    • 0027936755 scopus 로고
    • A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells
    • Han, J., Lee, J. D., Bibbs, L. and Ulevitch, R. J. (1994). A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells. Science 265, 808-811.
    • (1994) Science , vol.265 , pp. 808-811
    • Han, J.1    Lee, J.D.2    Bibbs, L.3    Ulevitch, R.J.4
  • 16
    • 0344708475 scopus 로고    scopus 로고
    • Tetraspanin proteins mediate cellular penetration, invasion, and fusion events and define a novel type of membrane microdomain
    • Hemler, M. E. (2003). Tetraspanin proteins mediate cellular penetration, invasion, and fusion events and define a novel type of membrane microdomain. Annu. Rev. Cell Dev. Biol. 19, 397-422.
    • (2003) Annu. Rev. Cell Dev. Biol. , vol.19 , pp. 397-422
    • Hemler, M.E.1
  • 17
    • 0021996405 scopus 로고
    • A monoclonal anti-human platelet antibody: A new platelet aggregating substance
    • Higashihara, M., Maeda, H., Shibata, Y., Kume, S. and Ohashi, T. (1985). A monoclonal anti-human platelet antibody: a new platelet aggregating substance. Blood 65, 382-391.
    • (1985) Blood , vol.65 , pp. 382-391
    • Higashihara, M.1    Maeda, H.2    Shibata, Y.3    Kume, S.4    Ohashi, T.5
  • 18
    • 0028963636 scopus 로고
    • The membrane protein CD9/DRAP 27 potentiates the juxtacrine growth factor activity of the membrane-anchored heparin-binding EGF-like growth factor
    • Higashiyama, S., Iwamoto, R., Goishi, K., Raab, G., Taniguchi, N., Klagsbrun, M. and Mekada, E. (1995). The membrane protein CD9/DRAP 27 potentiates the juxtacrine growth factor activity of the membrane-anchored heparin-binding EGF-like growth factor. J. Cell Biol. 128, 929-938.
    • (1995) J. Cell Biol. , vol.128 , pp. 929-938
    • Higashiyama, S.1    Iwamoto, R.2    Goishi, K.3    Raab, G.4    Taniguchi, N.5    Klagsbrun, M.6    Mekada, E.7
  • 19
    • 0030974057 scopus 로고    scopus 로고
    • Possible role of coexpression of CD9 with membrane-anchored heparin-binding EGF-like growth factor and amphiregulin in cultured human keratinocyte growth
    • Inui, S., Higashiyama, S., Hashimoto, K., Higashiyama, M., Yoshikawa, K. and Taniguchi, N. (1997). Possible role of coexpression of CD9 with membrane-anchored heparin-binding EGF-like growth factor and amphiregulin in cultured human keratinocyte growth. J. Cell Physiol. 171, 291-298.
    • (1997) J. Cell Physiol. , vol.171 , pp. 291-298
    • Inui, S.1    Higashiyama, S.2    Hashimoto, K.3    Higashiyama, M.4    Yoshikawa, K.5    Taniguchi, N.6
  • 20
    • 0030452494 scopus 로고    scopus 로고
    • Functional significance of CD9 association with beta 1 integrins in human epidermal keratinocytes
    • Jones, P. H., Bishop, L. A. and Watt, F. M. (1996). Functional significance of CD9 association with beta 1 integrins in human epidermal keratinocytes. Cell Adhes. Commun. 4, 297-305.
    • (1996) Cell Adhes. Commun. , vol.4 , pp. 297-305
    • Jones, P.H.1    Bishop, L.A.2    Watt, F.M.3
  • 21
    • 0026451026 scopus 로고
    • Monoclonal antibody AG-1 initiates platelet activation by a pathway dependent on glycoprotein IIb-IIIa and extracellular calcium
    • Kroll, M. H., Mendelsohn, M. E., Miller, J. L., Ballen, K. K., Hrbolich, J. K. and Schafer, A. I. (1992). Monoclonal antibody AG-1 initiates platelet activation by a pathway dependent on glycoprotein IIb-IIIa and extracellular calcium. Biochim. Biophys. Acta 1137, 248-256.
    • (1992) Biochim. Biophys. Acta , vol.1137 , pp. 248-256
    • Kroll, M.H.1    Mendelsohn, M.E.2    Miller, J.L.3    Ballen, K.K.4    Hrbolich, J.K.5    Schafer, A.I.6
  • 23
    • 0030947554 scopus 로고    scopus 로고
    • The tetraspanin superfamily: Molecular facilitators
    • Maecker, H. T., Todd, S. C. and Levy, S. (1997). The tetraspanin superfamily: molecular facilitators. FASEB J. 11, 428-442.
    • (1997) FASEB J. , vol.11 , pp. 428-442
    • Maecker, H.T.1    Todd, S.C.2    Levy, S.3
  • 28
    • 0030892234 scopus 로고    scopus 로고
    • Apoptosis by death factor
    • Nagata, S. (1997). Apoptosis by death factor. Cell 88, 355-365.
    • (1997) Cell , vol.88 , pp. 355-365
    • Nagata, S.1
  • 29
    • 0033178564 scopus 로고    scopus 로고
    • Requirement of activation of JNK and p38 for environmental stress-induced erythroid differentiation and apoptosis and of inhibition of ERK for apoptosis
    • Nagata, Y. and Todokoro, K. (1999). Requirement of activation of JNK and p38 for environmental stress-induced erythroid differentiation and apoptosis and of inhibition of ERK for apoptosis. Blood 94, 853-863.
    • (1999) Blood , vol.94 , pp. 853-863
    • Nagata, Y.1    Todokoro, K.2
  • 30
    • 0021996269 scopus 로고
    • Expression of the platelet-common acute lymphoblastic leukaemia associated antigen on normal eosinophils
    • Ohto, H., Shibata, Y., Takeuchi, A., Chen, R. F. and Maeda, H. (1985). Expression of the platelet-common acute lymphoblastic leukaemia associated antigen on normal eosinophils. Scand. J. Haematol. 34, 281-287.
    • (1985) Scand. J. Haematol. , vol.34 , pp. 281-287
    • Ohto, H.1    Shibata, Y.2    Takeuchi, A.3    Chen, R.F.4    Maeda, H.5
  • 31
    • 0030783255 scopus 로고    scopus 로고
    • The 66-kDa Shc isoform is a negative regulator of the epidermal growth factor-stimulated mitogen-activated protein kinase pathway
    • Okada, S., Kao, A. W., Ceresa, B. P., Blaikie, P., Margolis, B. and Pessin, J. E. (1997). The 66-kDa Shc isoform is a negative regulator of the epidermal growth factor-stimulated mitogen-activated protein kinase pathway. J. Biol. Chem. 272, 28042-28049.
    • (1997) J. Biol. Chem. , vol.272 , pp. 28042-28049
    • Okada, S.1    Kao, A.W.2    Ceresa, B.P.3    Blaikie, P.4    Margolis, B.5    Pessin, J.E.6
  • 32
    • 0033563253 scopus 로고    scopus 로고
    • Motility inhibition and apoptosis are induced by metastasis-suppressing gene product CD82 and its analogue CD9, with concurrent glycosylation
    • Ono, M., Hanada, K., Witheres, D. A. and Hakomori, S. (1999). Motility inhibition and apoptosis are induced by metastasis-suppressing gene product CD82 and its analogue CD9, with concurrent glycosylation. Cancer Res. 59, 2335-2339.
    • (1999) Cancer Res. , vol.59 , pp. 2335-2339
    • Ono, M.1    Hanada, K.2    Witheres, D.A.3    Hakomori, S.4
  • 36
    • 0026678172 scopus 로고
    • Association of the Shc and Grb2/Sem5 SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinase
    • Rozakis-Adcock, M., McGlade, J., Mbamalu, G., Pelicci, G., Daly, R., Li, W., Batzer, A., Thomas, S., Brugge, J., Pelicci, P. G. et al. (1992). Association of the Shc and Grb2/Sem5 SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinase. Nature 360, 689-692.
    • (1992) Nature , vol.360 , pp. 689-692
    • Rozakis-Adcock, M.1    McGlade, J.2    Mbamalu, G.3    Pelicci, G.4    Daly, R.5    Li, W.6    Batzer, A.7    Thomas, S.8    Brugge, J.9    Pelicci, P.G.10
  • 37
    • 10244261559 scopus 로고    scopus 로고
    • CD9, CD63, CD81, and CD82 are components of a surface tetraspan network connected to HLA-DR and VLA integrins
    • Rubinstein, E., le Naour, F., Lagaudriere-Gesbert, C., Billard, M., Conjeaud, H. and Boucheix, C. (1996). CD9, CD63, CD81, and CD82 are components of a surface tetraspan network connected to HLA-DR and VLA integrins. Eur. J. Immunol. 26, 2657-2665.
    • (1996) Eur. J. Immunol. , vol.26 , pp. 2657-2665
    • Rubinstein, E.1    le Naour, F.2    Lagaudriere-Gesbert, C.3    Billard, M.4    Conjeaud, H.5    Boucheix, C.6
  • 38
    • 0025992433 scopus 로고
    • Evidence that the signal-initiating membrane protein CD9 is associated with small GTP-binding proteins
    • Seehafer, J. G. and Shaw, A. R. (1991). Evidence that the signal-initiating membrane protein CD9 is associated with small GTP-binding proteins. Biochem. Biophys. Res. Commun. 179, 401-406.
    • (1991) Biochem. Biophys. Res. Commun. , vol.179 , pp. 401-406
    • Seehafer, J.G.1    Shaw, A.R.2
  • 39
    • 0028843757 scopus 로고
    • Ectopic expression of human and feline CD9 in a human B cell line confers β1 integrin-dependent motility on fibronectin and laminin substrates and enhanced tyrosine phosphorylation
    • Shaw, A. R., Domanska, A., Mak, A., Ginichrist, A., Dobler, K., Visser, L., Poppema, S., Fliegel, L., Letarte, M. and Willett, B. J. (1995). Ectopic expression of human and feline CD9 in a human B cell line confers β1 integrin-dependent motility on fibronectin and laminin substrates and enhanced tyrosine phosphorylation. J. Biol. Chem. 270, 24092-24099.
    • (1995) J. Biol. Chem. , vol.270 , pp. 24092-24099
    • Shaw, A.R.1    Domanska, A.2    Mak, A.3    Ginichrist, A.4    Dobler, K.5    Visser, L.6    Poppema, S.7    Fliegel, L.8    Letarte, M.9    Willett, B.J.10
  • 40
    • 0034614938 scopus 로고    scopus 로고
    • The tetraspanin CD9 associates with transmembrane TGF-alpha and regulates TGF-alpha-induced EGF receptor activation and cell proliferation
    • Shi, W., Fan, H., Shum, L. and Derynck, R. (2000). The tetraspanin CD9 associates with transmembrane TGF-alpha and regulates TGF-alpha-induced EGF receptor activation and cell proliferation. J. Cell Biol. 148, 591-602.
    • (2000) J. Cell Biol. , vol.148 , pp. 591-602
    • Shi, W.1    Fan, H.2    Shum, L.3    Derynck, R.4
  • 43
    • 0033598128 scopus 로고    scopus 로고
    • Role of transmembrane 4 superfamily (TM4SF) proteins CD9 and CD81 in muscle cell fusion and myotube maintenance
    • Tachibana, I. and Hemler, M. E. (1999). Role of transmembrane 4 superfamily (TM4SF) proteins CD9 and CD81 in muscle cell fusion and myotube maintenance. J. Cell Biol. 146, 893-904.
    • (1999) J. Cell Biol. , vol.146 , pp. 893-904
    • Tachibana, I.1    Hemler, M.E.2
  • 45
    • 0033021104 scopus 로고    scopus 로고
    • Motility-related protein (MRP-1/CD9) and KAI1/CD82 expression inversely correlate with lymph node metastasis in oesophageal squamous cell carcinoma
    • Uchida, S., Shimada, Y., Watanabe, G., Li, Z. G., Hong, T., Miyake, M. and Imamura, M. (1999). Motility-related protein (MRP-1/CD9) and KAI1/CD82 expression inversely correlate with lymph node metastasis in oesophageal squamous cell carcinoma. Br. J. Cancer 79, 1168-1173.
    • (1999) Br. J. Cancer , vol.79 , pp. 1168-1173
    • Uchida, S.1    Shimada, Y.2    Watanabe, G.3    Li, Z.G.4    Hong, T.5    Miyake, M.6    Imamura, M.7
  • 46
    • 0032527705 scopus 로고    scopus 로고
    • The cellular response to oxidative stress: Influences of mitogen-activated protein kinase signaling pathways on cell survival
    • Wang, X., Martindale, J. L., Liu, Y. and Holbrook, N. J. (1998). The cellular response to oxidative stress: influences of mitogen-activated protein kinase signaling pathways on cell survival. Biochem. J. 333, 291-300.
    • (1998) Biochem. J. , vol.333 , pp. 291-300
    • Wang, X.1    Martindale, J.L.2    Liu, Y.3    Holbrook, N.J.4
  • 47
    • 0030584077 scopus 로고    scopus 로고
    • The adaptor protein Shc couples a class of integrins to the control of cell cycle progression
    • Wary, K. K., Mainiero, F., Isakoff, S. J., Marcantonio, E. E. and Giancotti, F. G. (1996). The adaptor protein Shc couples a class of integrins to the control of cell cycle progression. Cell 87, 733-743.
    • (1996) Cell , vol.87 , pp. 733-743
    • Wary, K.K.1    Mainiero, F.2    Isakoff, S.J.3    Marcantonio, E.E.4    Giancotti, F.G.5
  • 48
    • 0032549670 scopus 로고    scopus 로고
    • Caspase-dependent cleavage of signaling proteins during apoptosis. A turn-off mechanism for anti-apoptotic signals
    • Widmann, C., Gibson, S. and Johnson, G. L. (1998). Caspase-dependent cleavage of signaling proteins during apoptosis. A turn-off mechanism for anti-apoptotic signals. J. Biol. Chem. 273, 7141-7147.
    • (1998) J. Biol. Chem. , vol.273 , pp. 7141-7147
    • Widmann, C.1    Gibson, S.2    Johnson, G.L.3
  • 49
    • 0028880006 scopus 로고
    • Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis
    • Xia, Z., Dickens, M., Raingeaud, J., Davis, R. J. and Greenberg, M. E. (1995). Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis. Science 270, 1326-1331.
    • (1995) Science , vol.270 , pp. 1326-1331
    • Xia, Z.1    Dickens, M.2    Raingeaud, J.3    Davis, R.J.4    Greenberg, M.E.5
  • 50
    • 0032482216 scopus 로고    scopus 로고
    • Regulation of endothelial cell motility by complexes of tetraspan molecules CD81/TATP-1 and CD151/PETA-3 with α3β1 integrin localized at endothelial lateral junctions
    • Yáñez-Mó, M., Alfranca, A., Cabañas, C., Marazuela, M., Tejedor, R., Ursa, A., Ashman, L. K., de Landá zuri, M. O. and Sanchez-Madrid, F. (1998). Regulation of endothelial cell motility by complexes of tetraspan molecules CD81/TATP-1 and CD151/PETA-3 with α3β1 integrin localized at endothelial lateral junctions. J. Cell Biol. 141, 791-804.
    • (1998) J. Cell Biol. , vol.141 , pp. 791-804
    • Yáñez-Mó, M.1    Alfranca, A.2    Cabañas, C.3    Marazuela, M.4    Tejedor, R.5    Ursa, A.6    Ashman, L.K.7    de Landázuri, M.O.8    Sanchez-Madrid, F.9
  • 51
    • 0027167768 scopus 로고
    • Anti-CD9 monoclonal antibody elicits staurosporine inhibitable phosphatidylinositol 4, 5-bisphosphate hydrolysis, phosphatidylinositol 3,4-bisphosphate synthesis, and protein-tyrosine phosphorylation in human platelets
    • Yatomi, Y., Ozaki, Y., Satoh, K. and Kume, S. (1993). Anti-CD9 monoclonal antibody elicits staurosporine inhibitable phosphatidylinositol 4, 5-bisphosphate hydrolysis, phosphatidylinositol 3,4-bisphosphate synthesis, and protein-tyrosine phosphorylation in human platelets. FEBS Lett. 322, 285-290.
    • (1993) FEBS Lett. , vol.322 , pp. 285-290
    • Yatomi, Y.1    Ozaki, Y.2    Satoh, K.3    Kume, S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.