Age-related changes in cardiac structure and function in Fischer 344 X Brown Norway hybrid rats

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 290, Issue 1, 2006, Pages

  Hacker, Timothy A ^a,d   McKiernan, Susan H ^b   Douglas, Pamela S ^c   Wanagat, Jonathan ^a   Aiken, Judd M ^b  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

^c DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d Medical Science   (United States)

Author keywords

Echocardiography; Hybrid rat

Indexed keywords

ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CORONARY HEMODYNAMICS; ECHOCARDIOGRAPHY; FUNCTIONAL ASSESSMENT; HEART FUNCTION; HEART RATE; HEMODYNAMICS; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RAT STRAIN; TISSUE SECTION; AGING; ANIMAL; BROWN NORWAY RAT; CROSS BREEDING; ELASTICITY; FIBROSIS; FISCHER 344 RAT; HEART; HEART VENTRICLE; HISTOLOGY; PATHOLOGY; PHYSIOLOGY; REFERENCE VALUE;

AGING; ANIMALS; BODY WEIGHT; CROSSES, GENETIC; ECHOCARDIOGRAPHY; ELASTICITY; FIBROSIS; HEART; HEART VENTRICLES; HEMODYNAMIC PROCESSES; MALE; RATS; RATS, INBRED BN; RATS, INBRED F344; REFERENCE VALUES;

EID: 33644814288     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00290.2005     Document Type: Article

References (55)

1. 2 consumption by NO in old Fischer 344 rats. Am J Physiol Heart Circ Physiol 285: H1015-H1022, 2003.
2. Anversa P, Hiler B, Ricci R, Guideri G, and Olivetti G. Myocyte cell loss and myocyte hypertrophy in the aging rat heart. J Am Coll Cardiol 8: 1441-1448, 1986.
3. Anversa P, Palackal T, Sonnenblick EH, Olivetti G, Meggs LG, and Capasso JM. Myocyte cell loss and myocyte cellular hyperplasia in the hypertrophied aging rat heart. Circ Res 67: 871-885, 1990.
4. Anversa P, Puntillo E, Nikitin P, Olivetti G, Capasso JM, and Sonnenblick EH. Effects of age on mechanical and structural properties of myocardium of Fischer 344 rats. Am J Physiol Heart Circ Physiol 256: H1440-H1449, 1989.
5. Arosio B, Perlini S, Calabresi C, Tozzi R, Palladini G, Ferrari AU, Vergani C, and Annoni G. Adenosine A1 and A2A receptor cross-talk during ageing in the rat myocardium. Exp Gerontol 38: 855-861, 2003.
6. Besse S, Assayag P, Delcayre C, Carre F, Cheav SL, Lecarpentier Y, and Swynghedauw B. Normal and hypertrophied senescent rat heart: mechanical and molecular characteristics. Am J Physiol Heart Circ Physiol 265: H183-H190, 1993.
7. Bezerra DG and Mandarim-de-Lacerda CA. Beneficial effect of simvastatin and pravastatin treatment on adverse cardiac remodelling and glomeruli loss in spontaneously hypertensive rats. Clin Sci (Lond) 108: 349-355, 2005.
8. Bing OH, Brooks WW, Robinson KG, Slawsky MT, Hayes JA, Litwin SE, Sen S, and Conrad CH. The spontaneously hypertensive rat as a model of the transition from compensated left ventricular hypertrophy to failure. J Mol Cell Cardiol 27: 383-396, 1995.
9. Boluyt MO, Converso K, Hwang HS, Mikkor A, and Russell MW. Echocardiographic assessment of age-associated changes in systolic and diastolic function of the female F344 rat heart. J Appl Physiol 96: 822-828, 2004.
10. Brown L, Fenning A, Chan V, Lock D, Wilson K, Anderson B, and Brustow D. Echocardiographic assessment of cardiac structure and function in rats. Heart Lung Circ 11: 167-173, 2002.
11. Burlew BS and Weber KT. Cardiac fibrosis as a cause of diastolic dysfunction. Herz 27: 92-98, 2002.
12. Cao Z, Wanagat J, McKiernan SH, and Aiken JM. Mitochondrial DNA deletion mutations are concomitant with ragged red regions of individual, aged muscle fibers: analysis by laser-capture microdissection. Nucleic Acids Res 29: 4502-4508, 2001.
13. Capasso JM, Fitzpatrick D, and Anversa P. Cellular mechanisms of ventricular failure: myocyte kinetics and geometry with age. Am J Physiol Heart Circ Physiol 262: H1770-H1781, 1992.
14. Capasso JM, Palackal T, Olivetti G, and Anversa P. Severe myocardial dysfunction induced by ventricular remodeling in aging rat hearts. Am J Physiol Heart Circ Physiol 259: H1086-H1096, 1990.
15. Chang KC, Peng YI, Dai SH, and Tseng YZ. Age-related changes in pumping mechanical behavior of rat ventricle in terms of systolic elastance and resistance. J Gerontol A Biol Sci Med Sci 55: B440-B447, 2000.
16. Chaves AA, Dech SJ, Nakayama T, Hamlin RL, Bauer JA, and Carnes CA. Age and anesthetic effects on murine electrocardiography. Life Sci 72: 2401-2412, 2003.
17. Devereux RB, Alonso DR, Lutas EM, Gottlieb GJ, Campo E, Sachs I, and Reichek N. Echocardiographic assessment of left ventricular hypertrophy: comparison to necropsy findings. Am J Cardiol 57: 450-458, 1986.
18. Devereux RB and Reichek N. Echocardiographic determination of left ventricular mass in man. Anatomic validation of the method. Circulation 55: 613-618, 1977.
19. Dobson JG Jr, Fray J, Leonard JL, and Pratt RE. Molecular mechanisms of reduced beta-adrenergic signaling in the aged heart as revealed by genomic profiling. Physiol Genomics 15: 142-147, 2003.
20. Fitzsimons DP, Patel JR, and Moss RL. Aging-dependent depression in the kinetics of force development in rat skinned myocardium. Am J Physiol Heart Circ Physiol 276: H1511-H1519, 1999.
21. Forman DE, Cittadini A, Azhar G, Douglas PS, and Wei JY. Cardiac morphology and function in senescent rats: gender-related differences. J Am Coll Cardiol 30: 1872-1877, 1997.
22. Harris SP, Bartley CR, Hacker TA, McDonald KS, Douglas PS, Greaser ML, Powers PA, and Moss RL. Hypertrophic cardiomyopathy in cardiac myosin binding protein-C knockout mice. Circ Res 90: 594-601, 2002.
23. Iemitsu M, Miyauchi T, Maeda S, Tanabe T, Irukayama-Tomobe Y, Goto K, Matsuda M, and Yamaguchi I. Effects of aging and subsequent exercise training on gene expression of endothelin-1 in rat heart. Clin Sci (Lond) 103, Suppl 48: 152S-157S, 2002.
24. Ikeda S, Hamada M, Qu P, Hiasa G, Hashida H, Shigematsu Y, and Hiwada K. Relationship between cardiomyocyte cell death and cardiac function during hypertensive cardiac remodelling in Dahl rats. Clin Sci (Lond) 102: 329-335, 2002.
25. Kelley GR and Herlihy JT. Food restriction alters the age-related decline in cardiac β-adrenergic responsiveness. Mech Ageing Dev 103: 1-12, 1998.
26. Krinke G. The Laboratory Rat. San Diego, CA: Academic, 2000, p. 349.
27. Kujoth GC, Hiona A, Pugh TD, Someya S, Panzer K, Wohlgemuth SE, Hofer T, Seo AY, Sullivan R, Jobling WA, Morrow JD, Van Remmen H, Sedivy JM, Yamasoba T, Tanokura M, Weindruch R, Leeuwenburgh C, and Prolla TA. Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging. Science 309: 481-484, 2005.
28. Kuoppala A, Shiota N, Lindstedt KA, Rysa J, Leskinen HK, Luodonpaa M, Liesmaa I, Ruskoaho H, Kaaja R, Kovanen PT, and Kokkonen JO. Expression of bradykinin receptors in the left ventricles of rats with pressure overload hypertrophy and heart failure. J Hypertens 21: 1729-1736, 2003.
29. Lipman RD, Chrisp CE, Hazzard DG, and Bronson RT. Pathologic characterization of Brown Norway, Brown Norway X Fischer 344, and Fischer 344 X Brown Norway rats with relation to age. J Gerontol A Biol Sci Med Sci 51: B54-B59, 1996.
30. Moises VA, Ferreira RL, Nozawa E, Kanashiro RM, Campos O, Andrade JL, Carvalho AC, and Tucci PJ. Structural and functional characteristics of rat hearts with and without myocardial infarct. Initial experience with Doppler echocardiography. Arq Bras Cardiol 75: 125-136, 2000.
31. Myreng Y and Nitter-Hauge S. Age-dependency of left ventricular filling dynamics and relaxation as assessed by pulsed Doppler echocardiography. Clin Physiol 9: 99-106, 1989.
32. Ono K, Masuyama T, Yamamoto K, Doi R, Sakata Y, Nishikawa N, Mano T, Kuzuya T, Takeda H, and Hori M. Echo Doppler assessment of left ventricular function in rats with hypertensive hypertrophy. J Am Soc Echocardiogr 15: 109-117, 2002.
33. Pacher P, Mabley JG, Liaudet L, Evgenov OV, Marton A, Hasko G, Kollai M, and Szabo C. Left ventricular pressure-volume relationship in a rat model of advanced aging-associated heart failure. Am J Physiol Heart Circ Physiol 287: H2132-H2137, 2004.
34. Pawlush DG, Moore RL, Musch TI, and Davidson WR Jr. Echocardiographic evaluation of size, function, and mass of normal and hypertrophied rat ventricles. J Appl Physiol 74: 2598-2605, 1993.
35. Pelouch V, Dixon IM, Golfman L, Beamish RE, and Dhalla NS. Role of extracellular matrix proteins in heart function. Mol Cell Biochem 129: 101-120, 1993.
36. Raya TE, Gaballa M, Anderson P, and Goldman S. Left ventricular function and remodeling after myocardial infarction in aging rats. Am J Physiol Heart Circ Physiol 273: H2652-H2658, 1997.
37. Reffelmann T and Kloner RA. Transthoracic echocardiography in rats. Evalution of commonly used indices of left ventricular dimensions, contractile performance, and hypertrophy in a genetic model of hypertrophic heart failure (SHHF-Mcc-facp-Rats) compared with Wistar rats during aging. Basic Res Cardiol 98: 275-284, 2003.
38. Romano FD and Dobson JG Jr. Adenosine attenuation of isoproterenol- stimulated adenylyl cyclase activity is enhanced with aging in the adult heart. Life Sci 58: 493-502, 1996.
39. Roth DM, Swaney JS, Dalton ND, Gilpin EA, and Ross J Jr. Impact of anesthesia on cardiac function during echocardiography in mice. Am J Physiol Heart Circ Physiol 282: H2134-H2140, 2002.
40. Schwarz ER, Pollick C, Dow J, Patterson M, Birnbaum Y, and Kloner RA. A small animal model of non-ischemic cardiomyopathy and its evaluation by transthoracic echocardiography. Cardiovasc Res 39: 216-223, 1998.
41. Schwarz ER, Pollick C, Meehan WP, and Kloner RA. Evaluation of cardiac structures and function in small experimental animals: transthoracic, transesophageal, and intraventricular echocardiography to assess contractile function in rat heart. Basic Res Cardiol 93: 477-486, 1998.
42. Shimizu G, Zile MR, Blaustein AS, and Gaasch WH. Left ventricular chamber filling and midwall fiber lengthening in patients with left ventricular hypertrophy: overestimation of fiber velocities by conventional midwall measurements. Circulation 71: 266-272, 1985.
43. Slotwiner DJ, Devereux RB, Schwartz JE, Pickering TG, de Simone G, Ganau A, Saba PS, and Roman MJ. Relation of age to left ventricular function in clinically normal adults. Am J Cardiol 82: 621-626, 1998.
44. Snyder DL, Gayheart-Walsten PA, Rhie S, Wang W, and Roberts J. Effect of age, gender, rat strain, and dietary restriction, on norepinephrine release from cardiac synaptosomes. J Gerontol A Biol Sci Med Sci 53: B33-B41, 1998.
45. Spirito P and Maron BJ. Doppler echocardiography for assessing left ventricular diastolic function. Ann Intern Med 109: 122-126, 1988.
46. Turturro A, Witt WW, Lewis S, Hass BS, Lipman RD, and Hart RW. Growth curves and survival characteristics of the animals used in the Biomarkers of Aging Program. J Gerontol A Biol Sci Med Sci 54: B492-B501, 1999.
47. Vuyk J. Pharmacodynamics in the elderly. Best Pract Res Clin Anaesthesiol 17: 207-218, 2003.
48. Wahr PA, Michele DE, and Metzger JM. Effects of aging on single cardiac myocyte function in Fischer 344 X Brown Norway rats. Am J Physiol Heart Circ Physiol 279: H559-H565, 2000.
49. Wanagat J, Cao Z, Pathare P, and Aiken JM. Mitochondrial DNA deletion mutations colocalize with segmental electron transport system abnormalities, muscle fiber atrophy, fiber splitting, and oxidative damage in sarcopenia. FASEB J 15: 322-332, 2001.
50. Wanagat J, Wolff MR, and Aiken JM. Age-associated changes in function, structure and mitochondrial genetic and enzymatic abnormalities in the Fischer 344 X Brown Norway F(1) hybrid rat heart. J Mol Cell Cardiol 34: 17-28, 2002.
51. Watson LE, Sheth M, Denyer RF, and Dostal DE. Baseline echocardiographic values for adult male rats. J Am Soc Echocardiogr 17: 161-167, 2004.
52. Weber KT and Brilla CG. Pathological hypertrophy and cardiac interstitium. Fibrosis and renin-angiotensin-aldosterone system. Circulation 83: 1849-1865, 1991.
53. Weindruch R and Masoro EJ. Concerns about rodent models for aging research. J Gerontol 46: B87-B88, 1991.
54. Yurenev AP, DeQuattro V, and Devereux RB. Hypertensive heart disease: relationship of silent ischemia to coronary artery disease and left ventricular hypertrophy. Am Heart J 120: 928-933, 1990.
55. Zhang D, Mott JL, Farrar P, Ryerse JS, Chang SW, Stevens M, Denniger G, and Zassenhaus HP. Mitochondrial DNA mutations activate the mitochondrial apoptotic pathway and cause dilated cardiomyopathy. Cardiovasc Res 57: 147-157, 2003.