-
1
-
-
0031897103
-
Prevalence of diabetes, impaired fasting glucose, and impaired glucose tolerance in U.S. adults. The Third National Health and Nutrition Examination Survey, 1988-1994
-
Harris, M.I. et al. Prevalence of diabetes, impaired fasting glucose, and impaired glucose tolerance in U.S. adults. The Third National Health and Nutrition Examination Survey, 1988-1994. Diabetes Care 21, 518-524 (1998).
-
(1998)
Diabetes Care
, vol.21
, pp. 518-524
-
-
Harris, M.I.1
-
2
-
-
0033515429
-
Deconstructing type 2 diabetes
-
Taylor, S.I. Deconstructing type 2 diabetes. Cel1 97, 9-12 (1999).
-
(1999)
Cell
, vol.97
, pp. 9-12
-
-
Taylor, S.I.1
-
3
-
-
0035936763
-
New perspectives into the molecular pathogenesis and treatment of type 2 diabetes
-
Saltiel, A.R. New perspectives into the molecular pathogenesis and treatment of type 2 diabetes. Cell 104, 517-529 (2001).
-
(2001)
Cell
, vol.104
, pp. 517-529
-
-
Saltiel, A.R.1
-
4
-
-
0032797852
-
Regulation of glucose production by the liver
-
Nordlie, R.C., Foster, J.D. & Lange, A.J. Regulation of glucose production by the liver. Annu. Rev. Nutr. 19, 379-406 (1999).
-
(1999)
Annu. Rev. Nutr.
, vol.19
, pp. 379-406
-
-
Nordlie, R.C.1
Foster, J.D.2
Lange, A.J.3
-
5
-
-
0033593461
-
Signaling mechanisms that regulate glucose transport
-
Czech, M.P. & Corvera, S. Signaling mechanisms that regulate glucose transport. J. Biol. Chem. 274, 1865-1868 (1999).
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 1865-1868
-
-
Czech, M.P.1
Corvera, S.2
-
6
-
-
0033779714
-
Free fatty acids and pathogenesis of type 2 diabetes mellitus
-
Bergman, R.N. & Ader, M. Free fatty acids and pathogenesis of type 2 diabetes mellitus. Trends Endocrinol. Metab. 11, 351-356 (2000).
-
(2000)
Trends Endocrinol. Metab.
, vol.11
, pp. 351-356
-
-
Bergman, R.N.1
Ader, M.2
-
7
-
-
0030894850
-
The pancreatic β-cell as a fuel sensor: An electrophysiologist's viewpoint
-
Rorsman, P. The pancreatic β-cell as a fuel sensor: an electrophysiologist's viewpoint. Diabetologia 40, 487-495 (1997).
-
(1997)
Diabetologia
, vol.40
, pp. 487-495
-
-
Rorsman, P.1
-
8
-
-
0025879424
-
Complementary DNA sequencing: Expressed sequence tags and human genome project
-
Adams, M.D. et al. Complementary DNA sequencing: expressed sequence tags and human genome project. Science 252, 1651-1656 (1991).
-
(1991)
Science
, vol.252
, pp. 1651-1656
-
-
Adams, M.D.1
-
9
-
-
0029355897
-
ESTablishing a human transcript map
-
Boguski, M.S. & Schuler, G.D. ESTablishing a human transcript map. Nat. Genet. 10,369-371 (1995).
-
(1995)
Nat. Genet.
, vol.10
, pp. 369-371
-
-
Boguski, M.S.1
Schuler, G.D.2
-
10
-
-
2042437650
-
Initial sequencing and analysis of the human genome
-
Lander, E.S. et al. Initial sequencing and analysis of the human genome. Nature 409, 860-921 (2001).
-
(2001)
Nature
, vol.409
, pp. 860-921
-
-
Lander, E.S.1
-
11
-
-
0035895505
-
The sequence of the human genome
-
Venter, J.C. et al. The sequence of the human genome. Science 291, 1304-1351 (2001).
-
(2001)
Science
, vol.291
, pp. 1304-1351
-
-
Venter, J.C.1
-
12
-
-
0029737070
-
Bone morphogenetic proteins: Multifunctional regulators of vertebrate development
-
Hogan, B.L. Bone morphogenetic proteins: multifunctional regulators of vertebrate development. Genes Dev. 10, 1580-1594 (1996).
-
(1996)
Genes Dev.
, vol.10
, pp. 1580-1594
-
-
Hogan, B.L.1
-
13
-
-
0031743421
-
Profile hidden Markov models
-
Eddy, S.R. Profile hidden Markov models. Bioinformatics, 14, 755-763 (1998).
-
(1998)
Bioinformatics
, vol.14
, pp. 755-763
-
-
Eddy, S.R.1
-
14
-
-
0036294517
-
Human secretory signal peptide description by hidden Markov model and generation of a strong artificial signal peptide for secreted protein expression
-
Barash, S., Wang, W. & Shi, Y. Human secretory signal peptide description by hidden Markov model and generation of a strong artificial signal peptide for secreted protein expression. Biochem. Biophys. Res. Commun. 294, 835-842 (2002).
-
(2002)
Biochem. Biophys. Res. Commun.
, vol.294
, pp. 835-842
-
-
Barash, S.1
Wang, W.2
Shi, Y.3
-
15
-
-
0030614959
-
Identification of prokaryotic and eukaryotic signal peptides and prediction of their cleavage sites
-
Nielsen, H., Engelbrecht, J., Brunak, S. & von Heijne, G. Identification of prokaryotic and eukaryotic signal peptides and prediction of their cleavage sites. Protein Eng. 10, 1-6 (1997).
-
(1997)
Protein Eng.
, vol.10
, pp. 1-6
-
-
Nielsen, H.1
Engelbrecht, J.2
Brunak, S.3
Von Heijne, G.4
-
16
-
-
0028071564
-
The SWISS-PROT protein sequence data bank: Current status
-
Bairoch, A. & Boeckmann, B. The SWISS-PROT protein sequence data bank: current status. Nucleic Acids Res. 22, 3578-3580 (1994).
-
(1994)
Nucleic Acids Res.
, vol.22
, pp. 3578-3580
-
-
Bairoch, A.1
Boeckmann, B.2
-
17
-
-
0026488079
-
Increased rate of gluconeogenesis in type II diabetes mellitus. A 13C nuclear magnetic resonance study
-
Magnusson, I., Rothman, D.L., Katz, L.D., Shulman, R.G. & Shulman, G.I. Increased rate of gluconeogenesis in type II diabetes mellitus. A 13C nuclear magnetic resonance study. J. Clin. Invest. 90, 1323-1327 (1992).
-
(1992)
J. Clin. Invest.
, vol.90
, pp. 1323-1327
-
-
Magnusson, I.1
Rothman, D.L.2
Katz, L.D.3
Shulman, R.G.4
Shulman, G.I.5
-
18
-
-
0035368548
-
Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKB-β)
-
Cho, H. et al. Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKB-β). Science 292, 1728-1731 (2001).
-
(2001)
Science
, vol.292
, pp. 1728-1731
-
-
Cho, H.1
-
19
-
-
0029587224
-
Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B
-
Cross, D.A., Alessi, D.R., Cohen, R, Andjelkovich, M. & Hemmings, B.A. Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B. Nature 378, 785-789 (1995).
-
(1995)
Nature
, vol.378
, pp. 785-789
-
-
Cross, D.A.1
Alessi, D.R.2
Cohen, R.3
Andjelkovich, M.4
Hemmings, B.A.5
-
20
-
-
0034975220
-
The role of lipids in the pathogenesis of muscle insulin resistance and β-cell failure in type II diabetes and obesity
-
Kraegen, E.W., Cooney, G.J., Ye, J.M., Thompson, A.L. & Furler, S.M. The role of lipids in the pathogenesis of muscle insulin resistance and β-cell failure in type II diabetes and obesity. Exp. Clin. Endocrinol. Diabetes 109, S189-S201 (2001).
-
(2001)
Exp. Clin. Endocrinol. Diabetes
, vol.109
-
-
Kraegen, E.W.1
Cooney, G.J.2
Ye, J.M.3
Thompson, A.L.4
Furler, S.M.5
-
21
-
-
0034804703
-
Insulin resistance and its impact on the approach to therapy of type 2 diabetes
-
Laakso, M. Insulin resistance and its impact on the approach to therapy of type 2 diabetes. Int. J. Clin. Pract. (Suppl.) 8-12 (2001).
-
(2001)
Int. J. Clin. Pract. (Suppl.)
, pp. 8-12
-
-
Laakso, M.1
-
22
-
-
0028029797
-
The peroxisome proliferator activated receptor regulates malic enzyme gene expression
-
Castelein, H. et al. The peroxisome proliferator activated receptor regulates malic enzyme gene expression. J. Biol. Chem. 269, 26754-26758 (1994).
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 26754-26758
-
-
Castelein, H.1
-
23
-
-
0025275123
-
Identification of a thyroid hormone response element in the malic enzyme gene
-
Petty, K.J., Desvergne, B., Mitsuhashi, T. & Nikodem, V.M. Identification of a thyroid hormone response element in the malic enzyme gene. J. Biol. Chem. 265, 7395-7400 (1990).
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 7395-7400
-
-
Petty, K.J.1
Desvergne, B.2
Mitsuhashi, T.3
Nikodem, V.M.4
-
24
-
-
0033580999
-
Santisteban, R Insulin-induced early growth response gene (Egr-1) mediates a short term repression of rat malic enzyme gene transcription
-
Barroso, I. & Santisteban, R Insulin-induced early growth response gene (Egr-1) mediates a short term repression of rat malic enzyme gene transcription. J. Biol. Chem. 274, 17997-18004 (1999).
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 17997-18004
-
-
Barroso, I.1
-
25
-
-
0036251153
-
SREBPs: Activators of the complete program of cholesterol and fatty acid synthesis in the liver
-
Horton, J.D., Goldstein, J.L. & Brown, M.S. SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver. J. Clin. Invest. 109, 1125-1131 (2002).
-
(2002)
J. Clin. Invest.
, vol.109
, pp. 1125-1131
-
-
Horton, J.D.1
Goldstein, J.L.2
Brown, M.S.3
-
26
-
-
0035514942
-
Adenovirus-mediated overexpression of sterol regulatory element binding protein-1c mimics insulin effects on hepatic gene expression and glucose homeostasis in diabetic mice
-
Becard, D. et al. Adenovirus-mediated overexpression of sterol regulatory element binding protein-1c mimics insulin effects on hepatic gene expression and glucose homeostasis in diabetic mice. Diabetes 50, 2425-2430 (2001).
-
(2001)
Diabetes
, vol.50
, pp. 2425-2430
-
-
Becard, D.1
-
27
-
-
0033838459
-
Insulin-activated protein kinase Cβ bypasses Ras and stimulates mitogen-activated protein kinase activity and cell proliferation in muscle cells
-
Formisano, P. et al. Insulin-activated protein kinase Cβ bypasses Ras and stimulates mitogen-activated protein kinase activity and cell proliferation in muscle cells. Mol. Cell Blol. 20, 6323-6333 (2000).
-
(2000)
Mol. Cell Blol.
, vol.20
, pp. 6323-6333
-
-
Formisano, P.1
-
28
-
-
0036083619
-
Pro-adipogenic effect of leptin on rat pre-adipocytes in vitro: Activation of MAPK and STAT 3 signaling pathways
-
Machinal-Quelin, F., Dieudonne, M.N., Leneveu, M.C., Pecquery, R. & Giudicelli, Y. Pro-adipogenic effect of leptin on rat pre-adipocytes in vitro: activation of MAPK and STAT3 signaling pathways. Am. J. Physiol. Cell Physiol. 282, C853-C863 (2002).
-
(2002)
Am. J. Physiol. Cell Physiol.
, vol.282
-
-
Machinal-Quelin, F.1
Dieudonne, M.N.2
Leneveu, M.C.3
Pecquery, R.4
Giudicelli, Y.5
-
29
-
-
0036830457
-
Inhibition of adipocyte differentiation by resistin-like molecule? Biochemical characterization of its oligomeric nature
-
Blagoev, B. et al. Inhibition of adipocyte differentiation by resistin-like molecule? Biochemical characterization of its oligomeric nature. J. Biol. Chem. 277, 42011-42016 (2002).
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 42011-42016
-
-
Blagoev, B.1
-
30
-
-
0028882261
-
BMP-7 is an inducer of nephrogenesis, and is also required for eye development and skeletal patterning
-
Luo, G. et al. BMP-7 is an inducer of nephrogenesis, and is also required for eye development and skeletal patterning. Genes Dev. 9, 2808-2820 (1995).
-
(1995)
Genes Dev.
, vol.9
, pp. 2808-2820
-
-
Luo, G.1
-
31
-
-
0029861824
-
Growth differentiation factor-9 is required during early ovarian folliculogenesis
-
Dong, J. et al. Growth differentiation factor-9 is required during early ovarian folliculogenesis. Nature 383, 531-535 (1996).
-
(1996)
Nature
, vol.383
, pp. 531-535
-
-
Dong, J.1
-
32
-
-
0029121286
-
Bone morphogenetic protein-9 binds to liver cells and stimulates proliferation
-
Song, J.J. et al. Bone morphogenetic protein-9 binds to liver cells and stimulates proliferation. Endocrinology 136, 4293-4297 (1995).
-
(1995)
Endocrinology
, vol.136
, pp. 4293-4297
-
-
Song, J.J.1
-
33
-
-
0034674782
-
Bone morphogenetic protein-9. An autocrine/paracrine cytokine in the liver
-
Miller, A.F., Harvey, S.A., Thies, R.S. & Olson, M.S. Bone morphogenetic protein-9. An autocrine/paracrine cytokine in the liver. J. Biol. Chem. 275, 17937-17945 (2000).
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 17937-17945
-
-
Miller, A.F.1
Harvey, S.A.2
Thies, R.S.3
Olson, M.S.4
-
34
-
-
0034127731
-
Use of bone morphogenetic protein-9 gene therapy to induce spinal arthrodesis in the rodent
-
Helm, G.A. et al. Use of bone morphogenetic protein-9 gene therapy to induce spinal arthrodesis in the rodent. J. Neurosurg. 92, 191-196 (2000).
-
(2000)
J. Neurosurg.
, vol.92
, pp. 191-196
-
-
Helm, G.A.1
-
35
-
-
0035159274
-
BMP-2 and BMP-9 promotes chondrogenic differentiation of human multipotential mesenchymal cells and overcomes the inhibitory effect of IL-1
-
Majumdar, M.K., Wang, E. & Morris, E.A. BMP-2 and BMP-9 promotes chondrogenic differentiation of human multipotential mesenchymal cells and overcomes the inhibitory effect of IL-1. J. Cell Physiol. 189, 275-284 (2001).
-
(2001)
J. Cell Physiol.
, vol.189
, pp. 275-284
-
-
Majumdar, M.K.1
Wang, E.2
Morris, E.A.3
-
36
-
-
0035831609
-
Morphologic analysis of BMP-9 gene therapy-induced osteogenesis
-
Varady, P. et al. Morphologic analysis of BMP-9 gene therapy-induced osteogenesis. Hum. Gene Ther. 12, 697-710 (2001).
-
(2001)
Hum. Gene Ther.
, vol.12
, pp. 697-710
-
-
Varady, P.1
-
37
-
-
0032973769
-
Bone morphogenetic protein 9 is a potent synergistic factor for murine hemopoietic progenitor cell generation and colony formation in serum-free cultures
-
Ploemacher, R.E., Engels, L.J., Mayer, A.E., Thies, S. & Neben, S. Bone morphogenetic protein 9 is a potent synergistic factor for murine hemopoietic progenitor cell generation and colony formation in serum-free cultures. Leukemia 13, 428-437 (1999).
-
(1999)
Leukemia
, vol.13
, pp. 428-437
-
-
Ploemacher, R.E.1
Engels, L.J.2
Mayer, A.E.3
Thies, S.4
Neben, S.5
-
38
-
-
0039598632
-
Induction and maintenance of the neuronal cholinergic phenotype In the central nervous system by BMP-9
-
Lopez-Coviella, I., Berse, B., Krauss, R., Thies, R.S. & Blusztajn, J.K. Induction and maintenance of the neuronal cholinergic phenotype In the central nervous system by BMP-9. Science 289, 313-316 (2000).
-
(2000)
Science
, vol.289
, pp. 313-316
-
-
Lopez-Coviella, I.1
Berse, B.2
Krauss, R.3
Thies, R.S.4
Blusztajn, J.K.5
-
39
-
-
77049176008
-
Influence of the liver on uptake of glucose by peripheral tissues
-
Lang, S., Goldstein, M.S. & Levine, R. Influence of the liver on uptake of glucose by peripheral tissues. Am. J. Physiol. 177, 447-450 (1955).
-
(1955)
Am. J. Physiol.
, vol.177
, pp. 447-450
-
-
Lang, S.1
Goldstein, M.S.2
Levine, R.3
-
40
-
-
84909940623
-
An effect of liver extracts on glucose tolerance in rats
-
Mertz, W. & Schwartz, K. An effect of liver extracts on glucose tolerance in rats. Am. J. Physiol. 203, 533-556 (1962).
-
(1962)
Am. J. Physiol.
, vol.203
, pp. 533-556
-
-
Mertz, W.1
Schwartz, K.2
-
41
-
-
0032752551
-
The HISS story overview: A novel hepatic neurohumoral regulation of peripheral insulin sensitivity in health and diabetes
-
Lautt, W.W. The HISS story overview: a novel hepatic neurohumoral regulation of peripheral insulin sensitivity in health and diabetes. Can. J. Physiol. Pharmacol. 77, 553-562 (1999).
-
(1999)
Can. J. Physiol. Pharmacol.
, vol.77
, pp. 553-562
-
-
Lautt, W.W.1
-
42
-
-
0037338366
-
TIP, a T cell factor identified using high-throughput screening approaches increases survival in an acute GVHD model
-
Fiscella, M. et al. TIP, a T cell factor identified using high-throughput screening approaches increases survival in an acute GVHD model. Nat. Biotechnol. 21, 302-307 (2003).
-
(2003)
Nat. Biotechnol.
, vol.21
, pp. 302-307
-
-
Fiscella, M.1
-
43
-
-
0027249595
-
dbEST - Database for "expressed sequence tags"
-
Boguski, M.S., Lowe, T.M. & Tolstoshev, C.M. dbEST - database for "expressed sequence tags". Nat. Genet. 4, 332-333 (1993).
-
(1993)
Nat. Genet.
, vol.4
, pp. 332-333
-
-
Boguski, M.S.1
Lowe, T.M.2
Tolstoshev, C.M.3
-
44
-
-
0034069495
-
Gene ontology: Tool for the unification of biology. The Gene Ontology Consortium
-
Ashburner, M. et al. Gene ontology: tool for the unification of biology. The Gene Ontology Consortium. Nat. Genet. 25, 25-29 (2000).
-
(2000)
Nat. Genet.
, vol.25
, pp. 25-29
-
-
Ashburner, M.1
-
45
-
-
0035162594
-
RefSeq and LocusLink: NCBI gene-centered resources
-
Pruitt, K.D. & Maglott, D.R. RefSeq and LocusLink: NCBI gene-centered resources. Nucleic Acids Res. 29, 137-140 (2001).
-
(2001)
Nucleic Acids Res.
, vol.29
, pp. 137-140
-
-
Pruitt, K.D.1
Maglott, D.R.2
-
46
-
-
0031669205
-
Enzyme-linked immunosorbent assay for measurement of JNK, ERK, and p 38 kinase activities
-
Forrer, P., Tamaskovic, R. & Jaussi, R. Enzyme-linked immunosorbent assay for measurement of JNK, ERK, and p38 kinase activities. Biot. Chem. 379, 1101-1111 (1998).
-
(1998)
Biot. Chem.
, vol.379
, pp. 1101-1111
-
-
Forrer, P.1
Tamaskovic, R.2
Jaussi, R.3
-
47
-
-
0034640401
-
The molecular physiology of hepatic nuclear factor 3 in the regulation of gluconeogenesis
-
Wang, J.C., Stafford, J.M., Scott, D.K., Sutherland, C. & Granner, D.K. The molecular physiology of hepatic nuclear factor 3 in the regulation of gluconeogenesis. J. Biol. Chem. 275, 14717-14721 (2000).
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 14717-14721
-
-
Wang, J.C.1
Stafford, J.M.2
Scott, D.K.3
Sutherland, C.4
Granner, D.K.5
|