Development of TEFs for PCB congeners by using an alternative biomarker - Thyroid hormone levels

Regulatory Toxicology and Pharmacology

Volumn 56, Issue 2, 2010, Pages 225-236

  Yang, Jian Ming ^a   Salmon, Andrew G ^a   Marty, Melanie A ^a  

^a CALIFORNIA ENVIRONMENTAL PROTECTION AGENCY   (United States)

Author keywords

Congener specific; Neurotoxicity; Polychlorinated biphenyls; Risk assessment; Thyroid hormone; Toxic equivalency factor

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; 3,3',4,4',5 PENTACHLOROBIPHENYL; DOPAMINE; ETHOXYRESORUFIN DEETHYLASE; LIVER ENZYME; PCB 118; PCB 153; PCB 28; PCB 77; POLYCHLORINATED BIPHENYL DERIVATIVE; THYROID HORMONE; THYROXINE; UNCLASSIFIED DRUG; BIOLOGICAL MARKER; POLYCHLORINATED BIPHENYL;

ANIMAL EXPERIMENT; ARTICLE; CALCULATION; CONTROLLED STUDY; DOPAMINE BRAIN LEVEL; ENZYME INDUCTION; LIVER TOXICITY; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT; RISK ASSESSMENT; SENSITIVITY ANALYSIS; THYROID HORMONE BLOOD LEVEL; TOXIC EQUIVALENCY FACTOR; TOXICITY TESTING; TOXICOLOGICAL PARAMETERS; ANIMAL; BRAIN; BREAST MILK; CHEMISTRY; COMPARATIVE STUDY; DRUG EFFECTS; GENETICS; HUMAN; LEWIS RAT; LIVER; LONG EVANS RAT; METABOLISM; PROCEDURES; SPECIES DIFFERENCE; SPRAGUE DAWLEY RAT; TOXICITY; TRENDS;

ANIMALS; BIOLOGICAL MARKERS; BRAIN; HUMANS; LIVER; MILK, HUMAN; POLYCHLORINATED BIPHENYLS; RATS; RATS, INBRED LEW; RATS, LONG-EVANS; RATS, SPRAGUE-DAWLEY; SPECIES SPECIFICITY; THYROID HORMONES; TOXICITY TESTS;

EID: 76849109667     PISSN: 02732300     EISSN: 10960295     Source Type: Journal    
DOI: 10.1016/j.yrtph.2009.12.008     Document Type: Article

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