A novel mechanism for polychlorinated biphenyl-induced decrease in serum thyroxine level in rats

Drug Metabolism and Disposition

Volumn 35, Issue 10, 2007, Pages 1949-1955

  Kato, Yoshihisa ^a   Ikushiro, Shin Ichi ^b   Takiguchi, Rie ^c   Haraguchi, Koichi ^d   Koga, Nobuyuki ^e   Uchida, Shinya ^c   Sakaki, Toshiyuki ^b   Yamada, Shizuo ^c   Kanno, Jun ^f   Degawa, Masakuni ^c  

^a TOKUSHIMA BUNRI UNIVERSITY   (Japan)

^b TOYAMA PREFECTURAL UNIVERSITY   (Japan)

^c UNIVERSITY OF SHIZUOKA   (Japan)

^d DAIICHI UNIVERSITY OF PHARMACY   (Japan)

^e NAKAMURA GAKUEN UNIVERSITY   (Japan)

^f NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCURONOSYLTRANSFERASE; IODINE 125; POLYCHLORINATED BIPHENYL; THYROTROPIN; THYROXINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG CLEARANCE; ENZYME ACTIVITY; FREE THYROXINE INDEX; GUNN RAT; LIVER LEVEL; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; STATISTICAL SIGNIFICANCE; STRAIN DIFFERENCE; THYROTROPIN BLOOD LEVEL; THYROXINE BLOOD LEVEL; TISSUE DISTRIBUTION; WISTAR RAT;

ANIMALS; BLOOD PROTEINS; ENVIRONMENTAL POLLUTANTS; GLUCURONOSYLTRANSFERASE; LIVER; MICROSOMES, LIVER; ORGAN SIZE; POLYCHLORINATED BIPHENYLS; PROTEIN BINDING; RATS; RATS, WISTAR; THYROXINE; TISSUE DISTRIBUTION; TRIIODOTHYRONINE;

RATTUS; RATTUS NORVEGICUS;

EID: 34748818295     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.107.017327     Document Type: Article

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