Structural requirements for the interaction of 91 hydroxylated polychlorinated biphenyls with estrogen and thyroid hormone receptors

Toxicological Sciences

Volumn 84, Issue 1, 2005, Pages 49-62

  Arulmozhiraja, Sundaram ^a   Shiraishi, Fujio ^a   Okumura, Tameo ^b   Iida, Mitsuru ^c   Takigami, Hidetaka ^a   Edmonds, John S ^a   Morita, Masatoshi ^a  

^a NATIONAL INSTITUTE FOR ENVIRONMENTAL STUDIES   (Japan)

^b Environ Pollution Control Center   (Japan)

^c OTSUKA PHARMACEUTICAL CO LTD   (Japan)

Author keywords

Chinese hamster ovary cell assay; Estrogenicity; Hydroxylated PCBs; Hydroxylated polychlorinated biphenyls; Structure activity relationships; Thyroid hormone activity; Yeast two hybrid assay

Indexed keywords

CHLORINE; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; HYDROXYL GROUP; LIOTHYRONINE; POLYCHLORINATED BIPHENYL DERIVATIVE; THYROID HORMONE RECEPTOR ALPHA;

ANIMAL CELL; ARTICLE; CELL ASSAY; CHO CELL; CONTROLLED STUDY; ENVIRONMENTAL EXPOSURE; ESTROGEN ACTIVITY; HORMONE ACTION; HUMAN; HYDROGEN BOND; NONHUMAN; POLARIZATION; REPORTER GENE; STRUCTURE ACTIVITY RELATION; THEORETICAL STUDY; TWO HYBRID SYSTEM; YEAST CELL;

ANIMALS; CHO CELLS; CRICETINAE; ESTROGEN RECEPTOR ALPHA; ESTROGENS; HUMANS; HYDROXYLATION; POLYCHLORINATED BIPHENYLS; RECEPTORS, THYROID HORMONE; SACCHAROMYCES CEREVISIAE; STRUCTURE-ACTIVITY RELATIONSHIP; THYROID GLAND;

CRICETINAE; CRICETULUS GRISEUS; MAMMALIA;

EID: 14844290247     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/kfi063     Document Type: Article

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