RECQL5 helicase: Connections to DNA recombination and RNA polymerase II transcription

DNA Repair

Volumn 9, Issue 3, 2010, Pages 345-353

  Aygün, Ozan ^a   Svejstrup, Jesper Q ^a  

^a IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

HELICASE; RECQL5 HELICASE; RNA POLYMERASE II; UNCLASSIFIED DRUG;

CHROMATIN; DNA RECOMBINATION; DNA TRANSCRIPTION; GENETIC CODE; GENETIC TRANSCRIPTION; GENOMIC INSTABILITY; HUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; REVIEW;

ANIMALS; DNA; GENOMIC INSTABILITY; HUMANS; RECOMBINATION, GENETIC; RECQ HELICASES; RNA POLYMERASE II; TRANSCRIPTION, GENETIC;

EUKARYOTA;

EID: 76749143650     PISSN: 15687864     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.dnarep.2009.12.008     Document Type: Review

References (72)

1. Kitao S., et al. Cloning of two new human helicase genes of the RecQ family: biological significance of multiple species in higher eukaryotes. Genomics 54 (1998) 443-452
2. Shimamoto A., Nishikawa K., Kitao S., and Furuichi Y. Human RecQ5beta, a large isomer of RecQ5 DNA helicase, localizes in the nucleoplasm and interacts with topoisomerases 3alpha and 3beta. Nucleic Acids Res 28 (2000) 1647-1655
3. Kawabe T., et al. Differential regulation of human RecQ family helicases in cell transformation and cell cycle. Oncogene 19 (2000) 4764-4772
4. Garcia P.L., Liu Y., Jiricny J., West S.C., and Janscak P. Human RECQ5beta, a protein with DNA helicase and strand-annealing activities in a single polypeptide. EMBO J 23 (2004) 2882-2891
5. Ren H., et al. The zinc-binding motif of human RECQ5beta suppresses the intrinsic strand-annealing activity of its DExH helicase domain and is essential for the helicase activity of the enzyme. Biochem J 412 (2008) 425-433
6. Wang W., et al. Functional relation among RecQ family helicases RecQL1, RecQL5, and BLM in cell growth and sister chromatid exchange formation. Mol Cell Biol 23 (2003) 3527-3535
7. Jeong Y.S., et al. Deficiency of Caenorhabditis elegans RecQ5 homologue reduces life span and increases sensitivity to ionizing radiation. DNA Repair (Amst) 2 (2003) 1309-1319
8. Nakayama M., Kawasaki K., Matsumoto K., and Shibata T. The possible roles of the DNA helicase and C-terminal domains in RECQ5/QE: complementation study in yeast. DNA Repair (Amst) 3 (2004) 369-378
9. Hu Y., et al. Recql5 and Blm RecQ DNA helicases have nonredundant roles in suppressing crossovers. Mol Cell Biol 25 (2005) 3431-3442
10. Nakayama M., et al. Relationships of Drosophila melanogaster RECQ5/QE to cell-cycle progression and DNA damage. FEBS Lett 580 (2006) 6938-6942
11. Hu Y., et al. RECQL5/Recql5 helicase regulates homologous recombination and suppresses tumor formation via disruption of Rad51 presynaptic filaments. Genes Dev 21 (2007) 3073-3084
12. Nakayama M., et al. Loss of RecQ5 leads to spontaneous mitotic defects and chromosomal aberrations in Drosophila melanogaster. DNA Repair (Amst) 8 (2009) 232-241
13. Barber L.J., et al. RTEL1 maintains genomic stability by suppressing homologous recombination. Cell 135 (2008) 261-271
14. Jeong S.M., Kawasaki K., Juni N., and Shibata T. Identification of Drosophila melanogaster RECQE as a member of a new family of RecQ homologues that is preferentially expressed in early embryos. Mol Gen Genet 263 (2000) 183-193
15. Wang W., et al. Possible association of BLM in decreasing DNA double strand breaks during DNA replication. Embo J 19 (2000) 3428-3435
16. Imamura O., et al. Werner and Bloom helicases are involved in DNA repair in a complementary fashion. Oncogene 21 (2002) 954-963
17. Seki M., Otsuki M., Ishii Y., Tada S., and Enomoto T. RecQ family helicases in genome stability: lessons from gene disruption studies in DT40 cells. Cell Cycle 7 (2008) 2472-2478
18. Ohhata T., et al. Cloning, genomic structure and chromosomal localization of the gene encoding mouse DNA helicase RECQL5beta. Gene 280 (2001) 59-66
19. Hu Y., Lu X., Zhou G., Barnes E.L., and Luo G. Recql5 plays an important role in DNA replication and cell survival after camptothecin treatment. Mol Biol Cell 20 (2009) 114-123
20. Aygun O., Svejstrup J., and Liu Y. A RECQ5-RNA polymerase II association identified by targeted proteomic analysis of human chromatin. Proc Natl Acad Sci USA 105 (2008) 8580-8584
21. Branzei D., and Foiani M. RecQ helicases queuing with Srs2 to disrupt Rad51 filaments and suppress recombination. Genes Dev 21 (2007) 3019-3026
22. Bugreev D.V., Yu X., Egelman E.H., and Mazin A.V. Novel pro- and anti-recombination activities of the Bloom's syndrome helicase. Genes Dev 21 (2007) 3085-3094
23. Aygun O., et al. Direct inhibition of RNA polymerase II transcription by RECQL5. J Biol Chem (2009)
24. Izumikawa K., et al. Association of human DNA helicase RecQ5beta with RNA polymerase II and its possible role in transcription. Biochem J 413 (2008) 505-516
25. Bohr V.A. Rising from the RecQ-age: the role of human RecQ helicases in genome maintenance. Trends Biochem Sci 33 (2008) 609-620
26. Kanagaraj R., Saydam N., Garcia P.L., Zheng L., and Janscak P. Human RECQ5beta helicase promotes strand exchange on synthetic DNA structures resembling a stalled replication fork. Nucleic Acids Res 34 (2006) 5217-5231
27. Svejstrup J.Q. The RNA polymerase II transcription cycle: cycling through chromatin. Biochim Biophys Acta 1677 (2004) 64-73
28. Orphanides G., and Reinberg D. A unified theory of gene expression. Cell 108 (2002) 439-451
29. Dvir A., Conaway J.W., and Conaway R.C. Mechanism of transcription initiation and promoter escape by RNA polymerase II. Curr Opin Genet Dev 11 (2001) 209-214
30. Jiang Y.W., et al. Mammalian mediator of transcriptional regulation and its possible role as an end-point of signal transduction pathways. Proc Natl Acad Sci USA 95 (1998) 8538-8543
31. Myers L.C., and Kornberg R.D. Mediator of transcriptional regulation. Annu Rev Biochem 69 (2000) 729-749
32. Conaway R.C., Sato S., Tomomori-Sato C., Yao T., and Conaway J.W. The mammalian Mediator complex and its role in transcriptional regulation. Trends Biochem Sci 30 (2005) 250-255
33. Malik S., and Roeder R.G. Dynamic regulation of pol II transcription by the mammalian Mediator complex. Trends Biochem Sci 30 (2005) 256-263
34. Roeder R.G. Transcriptional regulation and the role of diverse coactivators in animal cells. FEBS Lett 579 (2005) 909-915
35. Shilatifard A., Conaway R.C., and Conaway J.W. The RNA polymerase II elongation complex. Annu Rev Biochem 72 (2003) 693-715
36. Sims R.J., 3RD R., Belotserkovskaya D., and Reinberg. Elongation by RNA polymerase II: the short and long of it. Genes Dev 18 (2004) 2437-2468
37. Core L.J., and Lis J.T. Transcription regulation through promoter-proximal pausing of RNA polymerase II. Science 319 (2008) 1791-1792
38. Saunders A., Core L.J., and Lis J.T. Breaking barriers to transcription elongation. Nat Rev Mol Cell Biol 7 (2006) 557-567
39. Phatnani H.P., and Greenleaf A.L. Phosphorylation and functions of the RNA polymerase II CTD. Genes Dev 20 (2006) 2922-2936
40. Buratowski S. The CTD code. Nat Struct Biol 10 (2003) 679-680
41. Svejstrup J.Q. Mechanisms of transcription-coupled DNA repair. Nat Rev Mol Cell Biol 3 (2002) 21-29
42. Svejstrup J.Q. Contending with transcriptional arrest during RNAPII transcript elongation. Trends Biochem Sci 32 (2007) 165-171
43. Svejstrup J.Q. Chromatin elongation factors. Curr Opin Genet Dev 12 (2002) 156-161
44. Kizer K.O., et al. A novel domain in Set2 mediates RNA polymerase II interaction and couples histone H3 K36 methylation with transcript elongation. Mol Cell Biol 25 (2005) 3305-3316
45. Carty S.M., and Greenleaf A.L. Hyperphosphorylated C-terminal repeat domain-associating proteins in the nuclear proteome link transcription to DNA/chromatin modification and RNA processing. Mol Cell Proteomics 1 (2002) 598-610
46. Li J., Moazed D., and Gygi S.P. Association of the histone methyltransferase Set2 with RNA polymerase II plays a role in transcription elongation. J Biol Chem 277 (2002) 49383-49388
47. Krogan N.J., et al. Methylation of histone H3 by Set2 in Saccharomyces cerevisiae is linked to transcriptional elongation by RNA polymerase II. Mol Cell Biol 23 (2003) 4207-4218
48. Li B., Howe L., Anderson S., Yates J.R., 3RD J.L., and Workman. The Set2 histone methyltransferase functions through the phosphorylated carboxyl-terminal domain of RNA polymerase II. J Biol Chem 278 (2003) 8897-8903
49. Li M., et al. Solution structure of the Set2-Rpb1 interacting domain of human Set2 and its interaction with the hyperphosphorylated C-terminal domain of Rpb1. Proc Natl Acad Sci USA 102 (2005) 17636-17641
50. Vojnic E., Simon B., Strahl B.D., Sattler M., and Cramer P. Structure and carboxyl-terminal domain (CTD) binding of the Set2 SRI domain that couples histone H3 Lys36 methylation to transcription. J Biol Chem 281 (2006) 13-15
51. Saxe D., Datta A., and Jinks-Robertson S. Stimulation of mitotic recombination events by high levels of RNA polymerase II transcription in yeast. Mol Cell Biol 20 (2000) 5404-5414
52. Bratty J., Ferbeyre G., Molinaro C., and Cedergren R. Stimulation of mitotic recombination upon transcription from the yeast GAL1 promoter but not from other RNA polymerase I, II and III promoters. Curr Genet 30 (1996) 381-388
53. Nevo-Caspi Y., and Kupiec M. Transcriptional induction of Ty recombination in yeast. Proc Natl Acad Sci USA 91 (1994) 12711-12715
54. Nickoloff J.A. Transcription enhances intrachromosomal homologous recombination in mammalian cells. Mol Cell Biol 12 (1992) 5311-5318
55. Grimm C., Schaer P., Munz P., and Kohli J. The strong ADH1 promoter stimulates mitotic and meiotic recombination at the ADE6 gene of Schizosaccharomyces pombe. Mol Cell Biol 11 (1991) 289-298
56. Thomas B.J., and Rothstein R. Elevated recombination rates in transcriptionally active DNA. Cell 56 (1989) 619-630
57. Aguilera A. The connection between transcription and genomic instability. EMBO J 21 (2002) 195-201
58. Piruat J.I., and Aguilera A. A novel yeast gene, THO2, is involved in RNA pol II transcription and provides new evidence for transcriptional elongation-associated recombination. EMBO J 17 (1998) 4859-4872
59. Jimeno S., Rondon A.G., Luna R., and Aguilera A. The yeast THO complex and mRNA export factors link RNA metabolism with transcription and genome instability. EMBO J 21 (2002) 3526-3535
60. Huertas P., and Aguilera A. Cotranscriptionally formed DNA:RNA hybrids mediate transcription elongation impairment and transcription-associated recombination. Mol Cell 12 (2003) 711-721
61. Prado F., and Aguilera A. Impairment of replication fork progression mediates RNA polII transcription-associated recombination. EMBO J 24 (2005) 1267-1276
62. Gottipati P., Cassel T.N., Savolainen L., and Helleday T. Transcription-associated recombination is dependent on replication in Mammalian cells. Mol Cell Biol 28 (2008) 154-164
63. Ivessa A.S., et al. The Saccharomyces cerevisiae helicase Rrm3p facilitates replication past nonhistone protein-DNA complexes. Mol Cell 12 (2003) 1525-1536
64. Ivessa A.S., Zhou J.Q., Schulz V.P., Monson E.K., and Zakian V.A. Saccharomyces Rrm3p, a 5' to 3' DNA helicase that promotes replication fork progression through telomeric and subtelomeric DNA. Genes Dev 16 (2002) 1383-1396
65. Ivessa A.S., Zhou J.Q., and Zakian V.A. The Saccharomyces Pif1p DNA helicase and the highly related Rrm3p have opposite effects on replication fork progression in ribosomal DNA. Cell 100 (2000) 479-489
66. Azvolinsky A., Giresi P.G., Lieb J.D., and Zakian V.A. Highly transcribed RNA polymerase II genes are impediments to replication fork progression in Saccharomyces cerevisiae. Mol Cell 34 (2009) 722-734
67. Gomez-Lazaro M., Fernandez-Gomez F.J., and Jordan J. p53: twenty five years understanding the mechanism of genome protection. J Physiol Biochem 60 (2004) 287-307
68. Schaeffer L., et al. DNA repair helicase: a component of BTF2 (TFIIH) basic transcription factor. Science 260 (1993) 58-63
69. Feaver W.J., et al. Dual roles of a multiprotein complex from S. cerevisiae in transcription and DNA repair. Cell 75 (1993) 1379-1387
70. Svejstrup J.Q., et al. Different forms of TFIIH for transcription and DNA repair: holo-TFIIH and a nucleotide excision repairosome. Cell 80 (1995) 21-28
71. Coin F., et al. Nucleotide excision repair driven by the dissociation of CAK from TFIIH. Mol Cell 31 (2008) 9-20
72. Larkin M.A., et al. Clustal W and Clustal X version 2.0. Bioinformatics 23 (2007) 2947-2948