Mechanism of transcription initiation and promoter escape by RNA polymerase II

Current Opinion in Genetics and Development

Volumn 11, Issue 2, 2001, Pages 209-214

  Dvir, Arik ^a   Conaway, Joan Weliky ^b   Conaway, Ronald C ^b  

^a OAKLAND UNIVERSITY   (United States)

^b OKLAHOMA MEDICAL RESEARCH FOUNDATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHICKEN OVALBUMIN UPSTREAM PROMOTER TRANSCRIPTION FACTOR; MESSENGER RNA; RNA POLYMERASE II;

CROSS LINKING; CRYSTAL STRUCTURE; ENZYME ACTIVITY; ENZYME STRUCTURE; EUKARYOTE; GENETIC TRANSCRIPTION; MESSENGER RNA SYNTHESIS; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; REVIEW; TRANSCRIPTION INITIATION;

EUKARYOTA; GALLUS GALLUS;

EID: 0035313754     PISSN: 0959437X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0959-437X(00)00181-7     Document Type: Review

References (36)

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4. Architecture of RNA polymerase II and implications for the transcription mechanism
5. Electron crystal structure of an RNA polymerase II transcription elongation complex
6. Two-dimensional crystallography of TFIIB- and IIE-RNA polymerase II complexes: Implications for start site selection and initiation complex formation
7. Reconstitution of the transcription factor TFIIH: Assignment of functions for the three enzymatic subunits, XPB, XPD, and cdk7
8. Control of elongation by RNA polymerase II
9. DNA bending and wrapping around RNA polymerase: A 'revolutionary' model describing transcriptional mechanisms
10. Wrapping of promoter DNA around the RNA polymerase II initiation complex induced by TFIIF
11. Mechanism of promoter melting by the xeroderma pigmentosum complementation group B helicase of transcription factor IIH revealed by protein-DNA photo-cross-linking
12. Mechanism of ATP-dependent promoter melting by transcription factor IIH
13. Trajectory of DNA in the RNA polymerase II transcription preinitiation complex
14. Promoter escape by RNA polymerase II: A role for an ATP cofactor in suppression of arrest by polymerase at promoter-proximal sites
15. Initially transcribed sequences strongly affect the extent of abortive initiation by RNA polymerase II
16. Three transitions in the RNA polymerase II transcription complex during initiation
17. A role for TFIIH in controlling the activity of early RNA polymerase II elongation complexes
18. Promoter escape limits the rate of RNA polymerase II transcription and is enhanced by TFIIE, TFIIH, and ATP on negatively supercoiled DNA
19. Promoter-proximal stalling results from the inability to recruit transcription factor IIH to the transcription complex and is a regulated event
20. A kinetic model for the early steps of RNA synthesis by human RNA polymerase II
21. Dual roles for TFIIF in promoter escape by RNA polymerase II
22. A role for the TFIIH XPB DNA helicase in promoter escape by RNA polymerase II
23. Distinct roles for the helicases of TFIIH in transcript initiation and promoter escape
24. Promoter escape by RNA polymerase II. Formation of an escape competent intermediate is a prerequisite for exit of polymerase from the promoter
25. Repeated tertiary fold of RNA polymerase II and implications for DNA binding
26. RAP74 induces promoter contacts by RNA polymerase II upstream and downstream of a DNA bend centered on the TATA box
27. 1.9 Å resolution refined structure of TBP recognizing the minor groove of TATAAAAG
28. Co-crystal structure of TBP recognizing the minor groove of a TATA element
29. Crystal structure of a yeast TBP/TATA-box complex
30. Solution structure of the C-terminal core domain of human TFIIB: Similarity to cyclin A and interaction with TATA-binding protein
31. Crystal structure of a TFIIB-TBP-TATA-element ternary complex
32. Localization of subunits of transcription factors IIE and IIF immediately upstream of the transcriptional initiation site of the adenovirus major late promoter
33. Structure of the central core domain of TFIIEβ with a novel double-stranded DNA binding surface
34. A cryptic DNA binding domain in the C-terminus of RNA polymerase II general transcription factor RAP30
35. Structural homology between the Rap30 DNA-binding domain and linker histone H5: Implications for preinitiation complex assembly
36. Defective interplay of activators and repressors with TFIIH in Xeroderma Pigmentosum