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Volumn 2, Issue 3, 2009, Pages 149-159

Bile acids in treatment of ocular disease

Author keywords

Apoptosis; Bile acid; Neuroprotection; Retinal degeneration; Tauroursodeoxycholic acid; Traditional Chinese medicine; TUDCA; UDCA; Ursodeoxycholic acid

Indexed keywords

BILE ACID; NEUROPROTECTIVE AGENT; TAUROLITE; TAUROURSODEOXYCHOLIC ACID; UNCLASSIFIED DRUG; URSO FORTE; URSODEOXYCHOLIC ACID;

EID: 76449113179     PISSN: None     EISSN: 19368445     Source Type: Journal    
DOI: 10.1007/s12177-009-9030-x     Document Type: Review
Times cited : (72)

References (100)
  • 2
    • 59349116352 scopus 로고    scopus 로고
    • The use of bear bile as medicine versus tonic
    • Williamson DF and Phipps MJ, editors Seoul: TRAFFIC East Asia
    • Lee Y-J. The use of bear bile as medicine versus tonic. In: Williamson DF and Phipps MJ, editors. Proceedings of the Third International Symposium on the Trade in Bear Parts. Seoul: TRAFFIC East Asia; 1999. p. 122-126
    • (1999) Proceedings of the Third International Symposium on the Trade in Bear Parts , pp. 122-126
    • Lee, Y.-J.1
  • 3
  • 4
    • 76449093836 scopus 로고    scopus 로고
    • A bitter medicine: The use of bear bile in China
    • Williamson DF and Phipps MJ, editors Seoul: TRAFFIC East Asia
    • Gabriel GG.A bitter medicine: the use of bear bile in China. In: Williamson DF and Phipps MJ, editors. Proceedings of the Third International Symposium on the Trade in Bear Parts. Seoul: TRAFFIC East Asia; 1999. p. 116-120.
    • (1999) Proceedings of the Third International Symposium on the Trade in Bear Parts , pp. 116-120
    • Gabriel, G.G.1
  • 5
    • 67349155034 scopus 로고
    • Poaching: Oriental demand for undgam and paws decimates California bears
    • DG Hanson 1983 Poaching: Oriental demand for undgam and paws decimates California bears Audubon 85 127 128
    • (1983) Audubon , vol.85 , pp. 127-128
    • Hanson, D.G.1
  • 7
    • 76449099966 scopus 로고    scopus 로고
    • A galling business
    • 10.2307/4016817
    • J Raloff 2005 A galling business Sci News 168 250 252 10.2307/4016817
    • (2005) Sci News , vol.168 , pp. 250-252
    • Raloff, J.1
  • 10
    • 0343217504 scopus 로고
    • The Asian trade in bears and bear parts: Impacts and conservation recommendations
    • 10.2307/3872697
    • J Mills C Servheen 1994 The Asian trade in bears and bear parts: impacts and conservation recommendations Bears: Their Biology and Management 9 161 167 10.2307/3872697
    • (1994) Bears: Their Biology and Management , vol.9 , pp. 161-167
    • Mills, J.1    Servheen, C.2
  • 11
    • 0033611305 scopus 로고    scopus 로고
    • The continuing importance of bile acids in liver and intestinal disease
    • 10.1001/archinte.159.22.2647 1:STN:280:DC%2BD3c%2FmsVKhtw%3D%3D 10597755
    • AF Hofmann 1999 The continuing importance of bile acids in liver and intestinal disease Arch Intern Med 159 2647 2658 10.1001/archinte.159.22.2647 1:STN:280:DC%2BD3c%2FmsVKhtw%3D%3D 10597755
    • (1999) Arch Intern Med , vol.159 , pp. 2647-2658
    • Hofmann, A.F.1
  • 13
    • 0027482390 scopus 로고
    • Ursodeoxycholic acid in the Ursidae: Biliary bile acids of bears, pandas, and related carnivores
    • 1:CAS:528:DyaK2cXlsFGk 8263415
    • LR Hagey DL Crombie E Espinosa MC Carey H Igimi AF Hofmann 1993 Ursodeoxycholic acid in the Ursidae: biliary bile acids of bears, pandas, and related carnivores J Lipid Res 34 1911 1917 1:CAS:528:DyaK2cXlsFGk 8263415
    • (1993) J Lipid Res , vol.34 , pp. 1911-1917
    • Hagey, L.R.1    Crombie, D.L.2    Espinosa, E.3    Carey, M.C.4    Igimi, H.5    Hofmann, A.F.6
  • 15
    • 0022004055 scopus 로고
    • Studies of bile lipids and bile acids of wild North American black bears in Nova Scotia, showing a high content of ursodeoxycholic acid
    • DOI 10.1016/0022-4804(85)90024-1
    • AC MacDonald CN Williams 1985 Studies of bile lipids and bile acids of wild North American black bears in Nova Scotia, showing a high content of ursodeoxycholic acid J Surg Res 38 173 179 10.1016/0022-4804(85)90024-1 1:CAS:528:DyaL2MXhtFSns70%3D 3968875 (Pubitemid 15136761)
    • (1985) Journal of Surgical Research , vol.38 , Issue.2 , pp. 173-179
    • MacDonald, A.C.1    Williams, C.N.2
  • 16
    • 44749088963 scopus 로고    scopus 로고
    • Determination of bile acids in human serum by on-line restricted access material-ultra high-performance liquid chromatography-mass spectrometry
    • 10.1016/j.jchromb.2008.04.045 1:CAS:528:DC%2BD1cXnt1alt7c%3D 18514045
    • K Bentayeb R Batlle C Sanchez C Nerin C Domeno 2008 Determination of bile acids in human serum by on-line restricted access material-ultra high-performance liquid chromatography-mass spectrometry J Chromatogr B Analyt Technol Biomed Life Sci 869 1 8 10.1016/j.jchromb.2008.04.045 1:CAS:528:DC%2BD1cXnt1alt7c%3D 18514045
    • (2008) J Chromatogr B Analyt Technol Biomed Life Sci , vol.869 , pp. 1-8
    • Bentayeb, K.1    Batlle, R.2    Sanchez, C.3    Nerin, C.4    Domeno, C.5
  • 17
    • 0343519148 scopus 로고
    • Syntheses of ursodesoxycholic acid and its conjugated bile acid
    • 1:CAS:528:DyaG2MXnsl2ntg%3D%3D
    • T Kanazawa A Shimazaki T Sato T Hoshino 1954 Syntheses of ursodesoxycholic acid and its conjugated bile acid Proceedings of the Japanese Academy 30 391 394 1:CAS:528:DyaG2MXnsl2ntg%3D%3D
    • (1954) Proceedings of the Japanese Academy , vol.30 , pp. 391-394
    • Kanazawa, T.1    Shimazaki, A.2    Sato, T.3    Hoshino, T.4
  • 19
    • 0020318866 scopus 로고
    • Ursodeoxycholic acid in the treatment of cholesterol cholelithiasis. PART i
    • 10.1007/BF01393771 1:CAS:528:DyaL38XlsFGltbo%3D 7094795
    • WH Bachrach AF Hofmann 1982 Ursodeoxycholic acid in the treatment of cholesterol cholelithiasis. PART I Dig Dis Sci 27 737 761 10.1007/BF01393771 1:CAS:528:DyaL38XlsFGltbo%3D 7094795
    • (1982) Dig Dis Sci , vol.27 , pp. 737-761
    • Bachrach, W.H.1    Hofmann, A.F.2
  • 20
    • 0021335877 scopus 로고
    • Ursodeoxycholic acid. A review of its pharmacological properties and therapeutic efficacy
    • A Ward RN Brogden RC Heel TM Speight GS Avery 1984 Ursodeoxycholic acid: a review of its pharmacological properties and therapeutic efficacy Drugs 27 95 131 10.2165/00003495-198427020-00001 1:CAS:528:DyaL2cXhsFSntbo%3D 6365507 (Pubitemid 14223113)
    • (1984) Drugs , vol.27 , Issue.2 , pp. 95-131
    • Ward, A.1    Brogden, R.N.2    Heel, R.C.3
  • 21
    • 0027265104 scopus 로고
    • Effect of long-term treatment with ursodiol on clinical and biochemical features and biliary bile acid metabolism in patients with primary biliary cirrhosis
    • 1:STN:280:DyaK3s3ktlelsg%3D%3D 8480734
    • AK Batta, et al. 1993 Effect of long-term treatment with ursodiol on clinical and biochemical features and biliary bile acid metabolism in patients with primary biliary cirrhosis Am J Gastroenterol 88 691 700 1:STN:280:DyaK3s3ktlelsg%3D%3D 8480734
    • (1993) Am J Gastroenterol , vol.88 , pp. 691-700
    • Batta, A.K.1
  • 22
    • 0025611350 scopus 로고
    • A multi-center double-blind controlled trial of ursodeoxycholic acid for primary biliary cirrhosis
    • 1:STN:280:DyaK3M7it1GmsA%3D%3D 1980654
    • H Oka, et al. 1990 A multi-center double-blind controlled trial of ursodeoxycholic acid for primary biliary cirrhosis Gastroenterol Jpn 25 774 780 1:STN:280:DyaK3M7it1GmsA%3D%3D 1980654
    • (1990) Gastroenterol Jpn , vol.25 , pp. 774-780
    • Oka, H.1
  • 23
    • 0022397043 scopus 로고
    • Bioavailability, gastrointestinal transit, solubilization and faecal excretion of ursodeoxycholic acid in man
    • 10.1111/j.1365-2362.1985.tb00164.x 1:CAS:528:DyaL2MXltlCnsbs%3D 3930255
    • M Parquet EH Metman A Raizman JC Rambaud N Berthaux R Infante 1985 Bioavailability, gastrointestinal transit, solubilization and faecal excretion of ursodeoxycholic acid in man Eur J Clin Invest 15 171 178 10.1111/j.1365-2362. 1985.tb00164.x 1:CAS:528:DyaL2MXltlCnsbs%3D 3930255
    • (1985) Eur J Clin Invest , vol.15 , pp. 171-178
    • Parquet, M.1    Metman, E.H.2    Raizman, A.3    Rambaud, J.C.4    Berthaux, N.5    Infante, R.6
  • 24
    • 0028282836 scopus 로고
    • Ursodiol for hepatobiliary disorders
    • 1:STN:280:DyaK2c3ovVCjtg%3D%3D 8017748
    • RA Rubin TE Kowalski M Khandelwal PF Malet 1994 Ursodiol for hepatobiliary disorders Ann Intern Med 121 207 218 1:STN:280: DyaK2c3ovVCjtg%3D%3D 8017748
    • (1994) Ann Intern Med , vol.121 , pp. 207-218
    • Rubin, R.A.1    Kowalski, T.E.2    Khandelwal, M.3    Malet, P.F.4
  • 25
    • 0025047432 scopus 로고
    • Ursodeoxycholic acid-induced changes of plasma and urinary bile acids in patients with primary biliary cirrhosis
    • 10.1002/hep.1840120308 1:STN:280:DyaK3czot1OktA%3D%3D 2401455
    • A Stiehl, et al. 1990 Ursodeoxycholic acid-induced changes of plasma and urinary bile acids in patients with primary biliary cirrhosis Hepatology 12 492 497 10.1002/hep.1840120308 1:STN:280:DyaK3czot1OktA%3D%3D 2401455
    • (1990) Hepatology , vol.12 , pp. 492-497
    • Stiehl, A.1
  • 27
    • 0027998655 scopus 로고
    • Pharmacology of ursodeoxycholic acid, an enterohepatic drug
    • 10.3109/00365529409103618 1:STN:280:DyaK2M7isFektQ%3D%3D 7824870
    • AF Hofmann 1994 Pharmacology of ursodeoxycholic acid, an enterohepatic drug Scand J Gastroenterol Suppl 204 1 15 10.3109/00365529409103618 1:STN:280:DyaK2M7isFektQ%3D%3D 7824870
    • (1994) Scand J Gastroenterol Suppl , vol.204 , pp. 1-15
    • Hofmann, A.F.1
  • 28
    • 0025193141 scopus 로고
    • Comphrehensive study of the biliary bile acid composition of patients with cystic fibrosis and associated liver disease before and after UDCA administration
    • DOI 10.1002/hep.1840120221
    • M Nakagawa C Colombo KD Setchell 1990 Comprehensive study of the biliary bile acid composition of patients with cystic fibrosis and associated liver disease before and after UDCA administration Hepatology 12 322 334 10.1002/hep.1840120221 1:STN:280:DyaK3czmtFahsQ%3D%3D 2391071 (Pubitemid 20285797)
    • (1990) Hepatology , vol.12 , Issue.2 , pp. 322-334
    • Nakagawa, M.1    Colombo, C.2    Setchell, K.D.R.3
  • 29
    • 0036725044 scopus 로고    scopus 로고
    • Ursodeoxycholic acid in cholestatic liver disease: Mechanisms of action and therapeutic use revisited
    • DOI 10.1053/jhep.2002.36088
    • G Paumgartner U Beuers 2002 Ursodeoxycholic acid in cholestatic liver disease: mechanisms of action and therapeutic use revisited Hepatology 36 525 531 10.1053/jhep.2002.36088 1:CAS:528:DC%2BD38XnvVSkt74%3D 12198643 (Pubitemid 34977162)
    • (2002) Hepatology , vol.36 , Issue.3 , pp. 525-531
    • Paumgartner, G.1    Beuers, U.2
  • 30
    • 0019943326 scopus 로고
    • Ursodeoxycholic acid: A safe and effective agent for dissolving cholesterol gallstones
    • 1:STN:280:DyaL383ot1ehtA%3D%3D 7051912
    • GS Tint G Salen A Colalillo D Graber D Verga J Speck S Shefer 1982 Ursodeoxycholic acid: a safe and effective agent for dissolving cholesterol gallstones Ann Intern Med 97 351 356 1:STN:280:DyaL383ot1ehtA%3D%3D 7051912
    • (1982) Ann Intern Med , vol.97 , pp. 351-356
    • Tint, G.S.1    Salen, G.2    Colalillo, A.3    Graber, D.4    Verga, D.5    Speck, J.6    Shefer, S.7
  • 31
    • 0026567831 scopus 로고
    • Intestinal absorption of ursodeoxycholic acid in patients with extrahepatic biliary obstruction and bile drainage
    • 1:STN:280:DyaK387msFSjug%3D%3D 1537519
    • S Walker G Rudolph R Raedsch A Stiehl 1992 Intestinal absorption of ursodeoxycholic acid in patients with extrahepatic biliary obstruction and bile drainage Gastroenterology 102 810 815 1:STN:280:DyaK387msFSjug%3D%3D 1537519
    • (1992) Gastroenterology , vol.102 , pp. 810-815
    • Walker, S.1    Rudolph, G.2    Raedsch, R.3    Stiehl, A.4
  • 32
    • 0029863605 scopus 로고    scopus 로고
    • Metabolism of orally administered tauroursodeoxycholic acid in patients with primary biliary cirrhosis
    • KD Setchell CM Rodrigues M Podda A Crosignani 1996 Metabolism of orally administered tauroursodeoxycholic acid in patients with primary biliary cirrhosis Gut 38 439 446 10.1136/gut.38.3.439 1:CAS:528:DyaK28XitlOjt7k%3D 8675100 (Pubitemid 26074325)
    • (1996) Gut , vol.38 , Issue.3 , pp. 439-446
    • Setchell, K.D.R.1    Rodrigues, C.M.P.2    Podda, M.3    Crosignani, A.4
  • 33
    • 0025829205 scopus 로고
    • Treatment of cholesterol gallstones with litholytic bile acids
    • 1:STN:280:DyaK3M3hs1Knuw%3D%3D 2022420
    • G Salen GS Tint S Shefer 1991 Treatment of cholesterol gallstones with litholytic bile acids Gastroenterol Clin North Am 20 171 182 1:STN:280:DyaK3M3hs1Knuw%3D%3D 2022420
    • (1991) Gastroenterol Clin North Am , vol.20 , pp. 171-182
    • Salen, G.1    Tint, G.S.2    Shefer, S.3
  • 34
    • 0031042798 scopus 로고    scopus 로고
    • Ursodeoxycholic acid in the treatment of liver diseases
    • 10.1136/pgmj.73.856.75 1:CAS:528:DyaK2sXhvVersrw%3D 9122101
    • S Saksena RK Tandon 1997 Ursodeoxycholic acid in the treatment of liver diseases Postgrad Med J 73 75 80 10.1136/pgmj.73.856.75 1:CAS:528: DyaK2sXhvVersrw%3D 9122101
    • (1997) Postgrad Med J , vol.73 , pp. 75-80
    • Saksena, S.1    Tandon, R.K.2
  • 35
    • 0021809682 scopus 로고
    • Gallstone dissolution with ursodeoxycholic acid in patients with chronic active hepatitis and two years follow-up. A pilot study
    • DOI 10.1007/BF01308413
    • U Leuschner M Leuschner J Sieratzki W Kurtz K Hubner 1985 Gallstone dissolution with ursodeoxycholic acid in patients with chronic active hepatitis and two years follow-up. A pilot study Dig Dis Sci 30 642 649 10.1007/BF01308413 1:STN:280:DyaL2M3ivF2jsw%3D%3D 4006646 (Pubitemid 15045039)
    • (1985) Digestive Diseases and Sciences , vol.30 , Issue.7 , pp. 642-649
    • Leuschner, U.1    Leuschner, M.2    Sieratzki, J.3
  • 36
    • 0031005366 scopus 로고    scopus 로고
    • Nuclear DNA fragmentation and expression of Bcl-2 in primary biliary cirrhosis
    • 10.1002/hep.510250505 1:STN:280:DyaK2s3os1amsQ%3D%3D 9141420
    • H Koga S Sakisaka M Ohishi M Sata K Tanikawa 1997 Nuclear DNA fragmentation and expression of Bcl-2 in primary biliary cirrhosis Hepatology 25 1077 1084 10.1002/hep.510250505 1:STN:280:DyaK2s3os1amsQ%3D%3D 9141420
    • (1997) Hepatology , vol.25 , pp. 1077-1084
    • Koga, H.1    Sakisaka, S.2    Ohishi, M.3    Sata, M.4    Tanikawa, K.5
  • 37
    • 0031950282 scopus 로고    scopus 로고
    • Ursodeoxycholic acid may inhibit deoxycholic acid-induced apoptosis by modulating mitochondrial transmembrane potential and reactive oxygen species production
    • 10.1007/s0089480040165 1:CAS:528:DyaK1cXis1Wksbw%3D 9562975
    • CM Rodrigues G Fan PY Wong BT Kren CJ Steer 1998 Ursodeoxycholic acid may inhibit deoxycholic acid-induced apoptosis by modulating mitochondrial transmembrane potential and reactive oxygen species production Mol Med 4 165 178 10.1007/s0089480040165 1:CAS:528:DyaK1cXis1Wksbw%3D 9562975
    • (1998) Mol Med , vol.4 , pp. 165-178
    • Rodrigues, C.M.1    Fan, G.2    Wong, P.Y.3    Kren, B.T.4    Steer, C.J.5
  • 38
    • 0032846812 scopus 로고    scopus 로고
    • Ursodeoxycholic acid prevents cytochrome c release in apoptosis by inhibiting mitochondrial membrane depolarization and channel formation
    • 10.1038/sj.cdd.4400560 1:CAS:528:DyaK1MXnt1Crt7s%3D 10510466
    • CM Rodrigues X Ma C Linehan-Stieers G Fan BT Kren CJ Steer 1999 Ursodeoxycholic acid prevents cytochrome c release in apoptosis by inhibiting mitochondrial membrane depolarization and channel formation Cell Death Differ 6 842 854 10.1038/sj.cdd.4400560 1:CAS:528:DyaK1MXnt1Crt7s%3D 10510466
    • (1999) Cell Death Differ , vol.6 , pp. 842-854
    • Rodrigues, C.M.1    Ma, X.2    Linehan-Stieers, C.3    Fan, G.4    Kren, B.T.5    Steer, C.J.6
  • 39
    • 0037452957 scopus 로고    scopus 로고
    • Tauroursodeoxycholic acid prevents Bax-induced membrane perturbation and cytochrome c release in isolated mitochondria
    • DOI 10.1021/bi026979d
    • CM Rodrigues S Sola JC Sharpe JJ Moura CJ Steer 2003 Tauroursodeoxycholic acid prevents Bax-induced membrane perturbation and cytochrome C release in isolated mitochondria Biochemistry 42 3070 3080 10.1021/bi026979d 1:CAS:528:DC%2BD3sXht1Oiu7s%3D 12627974 (Pubitemid 36331552)
    • (2003) Biochemistry , vol.42 , Issue.10 , pp. 3070-3080
    • Rodrigues, C.M.P.1    Sola, S.2    Sharpe, J.C.3    Moura, J.J.G.4    Steer, C.J.5
  • 40
    • 38849104576 scopus 로고    scopus 로고
    • Combination of ursodeoxycholic acid and glucocorticoids upregulates the AE2 alternate promoter in human liver cells
    • 1:CAS:528:DC%2BD1cXhsFOms7s%3D 18188457
    • F Arenas I Hervias M Uriz R Joplin J Prieto JF Medina 2008 Combination of ursodeoxycholic acid and glucocorticoids upregulates the AE2 alternate promoter in human liver cells J Clin Invest 118 695 709 1:CAS:528:DC%2BD1cXhsFOms7s%3D 18188457
    • (2008) J Clin Invest , vol.118 , pp. 695-709
    • Arenas, F.1    Hervias, I.2    Uriz, M.3    Joplin, R.4    Prieto, J.5    Medina, J.F.6
  • 41
    • 14844329900 scopus 로고    scopus 로고
    • Ursodeoxycholic acid induced activation of the glucocorticoid receptor in primary rat hepatocytes
    • DOI 10.1097/00042737-200502000-00007
    • C Weitzel D Stark F Kullmann J Scholmerich A Holstege W Falk 2005 Ursodeoxycholic acid induced activation of the glucocorticoid receptor in primary rat hepatocytes Eur J Gastroenterol Hepatol 17 169 177 10.1097/00042737-200502000-00007 1:CAS:528:DC%2BD2MXntVSrtA%3D%3D 15674094 (Pubitemid 40349530)
    • (2005) European Journal of Gastroenterology and Hepatology , vol.17 , Issue.2 , pp. 169-177
    • Weitzel, C.1    Stark, D.2    Kullmann, F.3    Scholmerich, J.4    Holstege, A.5    Falk, W.6
  • 43
    • 34247181117 scopus 로고    scopus 로고
    • Game and players: Mitochondrial apoptosis and the therapeutic potential of ursodeoxycholic acid
    • 1:CAS:528:DC%2BD2sXltlOgsrs%3D 17489439
    • S Sola MM Aranha CJ Steer CM Rodrigues 2007 Game and players: mitochondrial apoptosis and the therapeutic potential of ursodeoxycholic acid Curr Issues Mol Biol 9 123 138 1:CAS:528:DC%2BD2sXltlOgsrs%3D 17489439
    • (2007) Curr Issues Mol Biol , vol.9 , pp. 123-138
    • Sola, S.1    Aranha, M.M.2    Steer, C.J.3    Rodrigues, C.M.4
  • 44
    • 0033769186 scopus 로고    scopus 로고
    • Tauroursodeoxycholic acid partially prevents apoptosis induced by 3-nitropropionic acid: Evidence for a mitochondrial pathway independent of the permeability transition
    • DOI 10.1046/j.1471-4159.2000.0752368.x
    • CM Rodrigues CL Stieers CD Keene X Ma BT Kren WC Low CJ Steer 2000 Tauroursodeoxycholic acid partially prevents apoptosis induced by 3-nitropropionic acid: evidence for a mitochondrial pathway independent of the permeability transition J Neurochem 75 2368 2379 10.1046/j.1471-4159.2000. 0752368.x 1:CAS:528:DC%2BD3cXotFKnsr4%3D 11080188 (Pubitemid 30832739)
    • (2000) Journal of Neurochemistry , vol.75 , Issue.6 , pp. 2368-2379
    • Rodrigues, C.M.P.1    Linehan-Stieers, C.2    Keene, C.D.3    Ma, X.4    Kren, B.T.5    Low, W.C.6    Steer, C.J.7
  • 45
    • 0034799214 scopus 로고    scopus 로고
    • A bile acid protects against motor and cognitive deficits and reduces striatal degeneration in the 3-nitropropionic acid model of Huntington's disease
    • DOI 10.1006/exnr.2001.7755
    • CD Keene CM Rodrigues T Eich C Linehan-Stieers A Abt BT Kren CJ Steer WC Low 2001 A bile acid protects against motor and cognitive deficits and reduces striatal degeneration in the 3-nitropropionic acid model of Huntington's disease Exp Neurol 171 351 360 10.1006/exnr.2001.7755 1:CAS:528:DC%2BD3MXntV2nsbc%3D 11573988 (Pubitemid 32955297)
    • (2001) Experimental Neurology , vol.171 , Issue.2 , pp. 351-360
    • Keene C.Dirk1    Rodrigues, C.M.P.2    Eich, T.3    Linehan-Stieers, C.4    Abt, A.5    Kren, B.T.6    Steer, C.J.7    Low, W.C.8
  • 48
    • 62349110126 scopus 로고    scopus 로고
    • Tauroursodeoxycholic acid prevents E22Q Alzheimer's Abeta toxicity in human cerebral endothelial cells
    • 10.1007/s00018-009-8746-x 1:CAS:528:DC%2BD1MXjtFKqtr4%3D 19189048
    • RJ Viana, et al. 2009 Tauroursodeoxycholic acid prevents E22Q Alzheimer's Abeta toxicity in human cerebral endothelial cells Cell Mol Life Sci 66 1094 1104 10.1007/s00018-009-8746-x 1:CAS:528:DC%2BD1MXjtFKqtr4%3D 19189048
    • (2009) Cell Mol Life Sci , vol.66 , pp. 1094-1104
    • Viana, R.J.1
  • 49
    • 33746862168 scopus 로고    scopus 로고
    • Tauroursodeoxycholic acid modulates p53-mediated apoptosis in Alzheimer's disease mutant neuroblastoma cells
    • DOI 10.1111/j.1471-4159.2006.04007.x
    • RM Ramalho PM Borralho RE Castro S Sola CJ Steer CM Rodrigues 2006 Tauroursodeoxycholic acid modulates p53-mediated apoptosis in Alzheimer's disease mutant neuroblastoma cells J Neurochem 98 1610 1618 10.1111/j.1471-4159. 2006.04007.x 1:CAS:528:DC%2BD28XhtVymtLbM 16923170 (Pubitemid 44200450)
    • (2006) Journal of Neurochemistry , vol.98 , Issue.5 , pp. 1610-1618
    • Ramalho, R.M.1    Borralho, P.M.2    Castro, R.E.3    Sola, S.4    Steer, C.J.5    Rodrigues, C.M.P.6
  • 50
    • 39149099114 scopus 로고    scopus 로고
    • Bile acids and apoptosis modulation: An emerging role in experimental Alzheimer's disease
    • 10.1016/j.molmed.2007.12.001 1:CAS:528:DC%2BD1cXitVGlt7c%3D 18218342
    • RM Ramalho RJ Viana WC Low CJ Steer CM Rodrigues 2008 Bile acids and apoptosis modulation: an emerging role in experimental Alzheimer's disease Trends Mol Med 14 54 62 10.1016/j.molmed.2007.12.001 1:CAS:528: DC%2BD1cXitVGlt7c%3D 18218342
    • (2008) Trends Mol Med , vol.14 , pp. 54-62
    • Ramalho, R.M.1    Viana, R.J.2    Low, W.C.3    Steer, C.J.4    Rodrigues, C.M.5
  • 51
    • 44649156233 scopus 로고    scopus 로고
    • Apoptosis in transgenic mice expressing the P301L mutated form of human tau
    • DOI 10.2119/2007-00133.Ramalho
    • RM Ramalho RJ Viana RE Castro CJ Steer WC Low CM Rodrigues 2008 Apoptosis in transgenic mice expressing the P301L mutated form of human tau Mol Med 14 309 317 10.2119/2007-00133.Ramalho 1:CAS:528:DC%2BD1cXntV2gtLg%3D 18368144 (Pubitemid 351785704)
    • (2008) Molecular Medicine , vol.14 , Issue.5-6 , pp. 309-317
    • Ramalho, R.M.1    Viana, R.J.S.2    Castro, R.E.3    Steer, C.J.4    Low, W.C.5    Rodrigues, C.M.P.6
  • 52
    • 0034812181 scopus 로고    scopus 로고
    • Amyloid β-peptide disrupts mitochondrial membrane lipid and protein structure: Protective role of Tauroursodeoxycholate
    • DOI 10.1006/bbrc.2001.4370
    • CM Rodrigues S Sola MA Brito CD Brondino D Brites JJ Moura 2001 Amyloid beta-peptide disrupts mitochondrial membrane lipid and protein structure: protective role of tauroursodeoxycholate Biochem Biophys Res Commun 281 468 474 10.1006/bbrc.2001.4370 1:CAS:528:DC%2BD3MXht1aiur0%3D 11181071 (Pubitemid 32928179)
    • (2001) Biochemical and Biophysical Research Communications , vol.281 , Issue.2 , pp. 468-474
    • Rodrigues, C.M.P.1    Sola, S.2    Brito, M.A.3    Brondino, C.D.4    Brites, D.5    Moura, J.J.G.6
  • 53
    • 3042698849 scopus 로고    scopus 로고
    • Tauroursodeoxycholic acid prevents amyloid-beta peptide-induced neuronal death via a phosphatidylinositol 3-kinase-dependent signaling pathway
    • 10.2119/2003-00042.Rodrigues 1:CAS:528:DC%2BD2cXmtFygsr4%3D 15208744
    • S Sola RE Castro PA Laires CJ Steer CM Rodrigues 2003 Tauroursodeoxycholic acid prevents amyloid-beta peptide-induced neuronal death via a phosphatidylinositol 3-kinase-dependent signaling pathway Mol Med 9 226 234 10.2119/2003-00042.Rodrigues 1:CAS:528:DC%2BD2cXmtFygsr4%3D 15208744
    • (2003) Mol Med , vol.9 , pp. 226-234
    • Sola, S.1    Castro, R.E.2    Laires, P.A.3    Steer, C.J.4    Rodrigues, C.M.5
  • 54
    • 16644371986 scopus 로고    scopus 로고
    • Potential role of ursodeoxycholic acid in suppression of nuclear factor kappa B in microglial cell line (BV-2)
    • 10.1007/BF02975850 1:CAS:528:DC%2BD2cXptFajtbg%3D 15473667
    • SS Joo TJ Won DI Lee 2004 Potential role of ursodeoxycholic acid in suppression of nuclear factor kappa B in microglial cell line (BV-2) Arch Pharm Res 27 954 960 10.1007/BF02975850 1:CAS:528:DC%2BD2cXptFajtbg%3D 15473667
    • (2004) Arch Pharm Res , vol.27 , pp. 954-960
    • Joo, S.S.1    Won, T.J.2    Lee, D.I.3
  • 55
    • 0035998716 scopus 로고    scopus 로고
    • Tauroursodeoxycholic acid improves the survival and function of nigral transplants in a rat model of Parkinson's disease
    • 12075985
    • WM Duan CM Rodrigues LR Zhao CJ Steer WC Low 2002 Tauroursodeoxycholic acid improves the survival and function of nigral transplants in a rat model of Parkinson's disease Cell Transplant 11 195 205 12075985
    • (2002) Cell Transplant , vol.11 , pp. 195-205
    • Duan, W.M.1    Rodrigues, C.M.2    Zhao, L.R.3    Steer, C.J.4    Low, W.C.5
  • 57
  • 58
    • 6344279913 scopus 로고    scopus 로고
    • The bile acid tauroursodeoxycholic acid modulates phosphorylation and translocation of Bad via phosphatidylinositol 3-kinase in glutamate-induced apoptosis of rat cortical neurons
    • DOI 10.1124/jpet.104.070532
    • RE Castro S Sola RM Ramalho CJ Steer CM Rodrigues 2004 The bile acid tauroursodeoxycholic acid modulates phosphorylation and translocation of bad via phosphatidylinositol 3-kinase in glutamate-induced apoptosis of rat cortical neurons J Pharmacol Exp Ther 311 845 852 10.1124/jpet.104.070532 1:CAS:528:DC%2BD2cXptVKqsrs%3D 15190125 (Pubitemid 39391575)
    • (2004) Journal of Pharmacology and Experimental Therapeutics , vol.311 , Issue.2 , pp. 845-852
    • Castro, R.E.1    Sola, S.2    Ramalho, R.M.3    Steer, C.J.4    Rodrigues, C.M.P.5
  • 59
    • 56349117478 scopus 로고    scopus 로고
    • Ursodeoxycholic acid prevents apoptosis of mouse sensory neurons induced by cisplatin by reducing P53 accumulation
    • 10.1016/j.bbrc.2008.06.014 1:CAS:528:DC%2BD1cXhsVGhu7%2FJ 18558085
    • IH Park MK Kim SU Kim 2008 Ursodeoxycholic acid prevents apoptosis of mouse sensory neurons induced by cisplatin by reducing P53 accumulation Biochem Biophys Res Commun 377 1025 1030 10.1016/j.bbrc.2008.06.014 1:CAS:528: DC%2BD1cXhsVGhu7%2FJ 18558085
    • (2008) Biochem Biophys Res Commun , vol.377 , pp. 1025-1030
    • Park, I.H.1    Kim, M.K.2    Kim, S.U.3
  • 60
    • 43049096711 scopus 로고    scopus 로고
    • Tauroursodeoxycholic acid and secondary damage after spinal cord injury in rats
    • 10.1016/j.jocn.2007.06.002 1:CAS:528:DC%2BD1cXlslGit7s%3D 18343118
    • A Colak B Kelten A Sagmanligil O Akdemir A Karaoglan E Sahan O Celik S Barut 2008 Tauroursodeoxycholic acid and secondary damage after spinal cord injury in rats J Clin Neurosci 15 665 671 10.1016/j.jocn.2007.06.002 1:CAS:528:DC%2BD1cXlslGit7s%3D 18343118
    • (2008) J Clin Neurosci , vol.15 , pp. 665-671
    • Colak, A.1    Kelten, B.2    Sagmanligil, A.3    Akdemir, O.4    Karaoglan, A.5    Sahan, E.6    Celik, O.7    Barut, S.8
  • 61
    • 0026006175 scopus 로고
    • Effect of bile acids on ischemia-reperfusion liver injury
    • 10.1016/0168-8278(91)90075-M 1:CAS:528:DyaK38XhtVelsb4%3D 1808225
    • O Chazouilleres F Ballet C Legendre MT Bonnefis C Rey Y Chretien R Poupon 1991 Effect of bile acids on ischemia-reperfusion liver injury J Hepatol 13 318 322 10.1016/0168-8278(91)90075-M 1:CAS:528:DyaK38XhtVelsb4%3D 1808225
    • (1991) J Hepatol , vol.13 , pp. 318-322
    • Chazouilleres, O.1    Ballet, F.2    Legendre, C.3    Bonnefis, M.T.4    Rey, C.5    Chretien, Y.6    Poupon, R.7
  • 62
    • 52649174283 scopus 로고    scopus 로고
    • TUDCA prevents cholestasis and canalicular damage induced by ischemia-reperfusion injury in the rat, modulating PKCalpha-ezrin pathway
    • 10.1111/j.1432-2277.2008.00682.x 1:CAS:528:DC%2BD1cXhtVSgt7vM 18435680
    • L Baiocchi, et al. 2008 TUDCA prevents cholestasis and canalicular damage induced by ischemia-reperfusion injury in the rat, modulating PKCalpha-ezrin pathway Transpl Int 21 792 800 10.1111/j.1432-2277.2008.00682.x 1:CAS:528:DC%2BD1cXhtVSgt7vM 18435680
    • (2008) Transpl Int , vol.21 , pp. 792-800
    • Baiocchi, L.1
  • 63
    • 0042167601 scopus 로고    scopus 로고
    • Protection against post-ischemic mitochondrial injury in rat liver by silymarin or TUDC
    • DOI 10.1016/S1386-6346(03)00108-6
    • AP Rolo PJ Oliveira AJ Moreno CM Palmeira 2003 Protection against post-ischemic mitochondrial injury in rat liver by silymarin or TUDC Hepatol Res 26 217 224 10.1016/S1386-6346(03)00108-6 1:CAS:528:DC%2BD3sXltF2msLs%3D 12850694 (Pubitemid 36927196)
    • (2003) Hepatology Research , vol.26 , Issue.3 , pp. 217-224
    • Rolo, A.P.1    Oliveira, P.J.2    Moreno, A.J.M.3    Pameira, C.M.4
  • 64
    • 0035957184 scopus 로고    scopus 로고
    • Cellular distribution of thrombomodulin as an early marker for warm ischemic liver injury in porcine liver transplantation: Protective effect of prostaglandin I2 analogue and tauroursodeoxycholic acid
    • 10.1097/00007890-200103270-00006 1:CAS:528:DC%2BD3MXjsleqtLY%3D 11330532
    • S Ejiri Y Eguchi A Kishida F Ishigami Y Kurumi T Tani M Kodama 2001 Cellular distribution of thrombomodulin as an early marker for warm ischemic liver injury in porcine liver transplantation: protective effect of prostaglandin I2 analogue and tauroursodeoxycholic acid Transplantation 71 721 726 10.1097/00007890-200103270-00006 1:CAS:528:DC%2BD3MXjsleqtLY%3D 11330532
    • (2001) Transplantation , vol.71 , pp. 721-726
    • Ejiri, S.1    Eguchi, Y.2    Kishida, A.3    Ishigami, F.4    Kurumi, Y.5    Tani, T.6    Kodama, M.7
  • 65
    • 0035872758 scopus 로고    scopus 로고
    • Protective role of tauroursodeoxycholate during harvesting and cold storage of human liver: A pilot study in transplant recipients
    • 10.1097/00007890-200105150-00015 1:CAS:528:DC%2BD3MXks1Clsbw%3D 11397961
    • L Falasca, et al. 2001 Protective role of tauroursodeoxycholate during harvesting and cold storage of human liver: a pilot study in transplant recipients Transplantation 71 1268 1276 10.1097/00007890-200105150-00015 1:CAS:528:DC%2BD3MXks1Clsbw%3D 11397961
    • (2001) Transplantation , vol.71 , pp. 1268-1276
    • Falasca, L.1
  • 66
    • 0035892910 scopus 로고    scopus 로고
    • Bile salt tauroursodeoxycholic acid modulation of Bax translocation to mitochondria protects the liver from warm ischemia-reperfusion injury in the rat
    • 10.1097/00007890-200112150-00016 1:CAS:528:DC%2BD38XltVKjuw%3D%3D 11740392
    • F Ishigami S Naka K Takeshita Y Kurumi K Hanasawa T Tani 2001 Bile salt tauroursodeoxycholic acid modulation of Bax translocation to mitochondria protects the liver from warm ischemia-reperfusion injury in the rat Transplantation 72 1803 1807 10.1097/00007890-200112150-00016 1:CAS:528:DC%2BD38XltVKjuw%3D%3D 11740392
    • (2001) Transplantation , vol.72 , pp. 1803-1807
    • Ishigami, F.1    Naka, S.2    Takeshita, K.3    Kurumi, Y.4    Hanasawa, K.5    Tani, T.6
  • 67
    • 0032739916 scopus 로고    scopus 로고
    • In vivo protection of the pig liver against ischemia/reperfusion injury by tauroursodeoxycholate
    • DOI 10.1007/s004230050231
    • M Hertl MC Hertl M Malago CE Broelsch 1999 In vivo protection of the pig liver against ischemia/reperfusion injury by tauroursodeoxycholate Langenbecks Arch Surg 384 461 466 10.1007/s004230050231 1:STN:280:DC%2BD3c%2FitVKqtA%3D%3D 10552292 (Pubitemid 29513734)
    • (1999) Langenbeck's Archives of Surgery , vol.384 , Issue.5 , pp. 461-466
    • Hertl, M.1    Hertl, M.C.2    Malago, M.3    Broelsch, C.E.4
  • 68
    • 0031734846 scopus 로고    scopus 로고
    • Tauroursodeoxycholic acid protects cholestasis in rat reperfused livers: Its roles in hepatic calcium mobilization
    • DOI 10.1023/A:1026654219668
    • T Ono K Imai H Kohno M Uchida Y Takemoto DK Dhar N Nagasue 1998 Tauroursodeoxycholic acid protects cholestasis in rat reperfused livers: its roles in hepatic calcium mobilization Dig Dis Sci 43 2201 2210 10.1023/A:1026654219668 1:CAS:528:DyaK1cXntFSgurs%3D 9790455 (Pubitemid 28487248)
    • (1998) Digestive Diseases and Sciences , vol.43 , Issue.10 , pp. 2201-2210
    • Ono, T.1    Imai, K.2    Kohno, H.3    Uchida, M.4    Takemoto, Y.5    Dhar, D.K.6    Nagasue, N.7
  • 69
    • 0028880364 scopus 로고
    • Effect of tauroursodeoxycholic acid on bile flow and calcium excretion in ischemia-reperfusion injury of rat livers
    • 10.1016/0168-8278(95)80066-2 1:CAS:528:DyaK28Xjt12m 8583148
    • T Ono N Nagasue H Kohno M Uchida Y Takemoto DK Dhar T Nakamura 1995 Effect of tauroursodeoxycholic acid on bile flow and calcium excretion in ischemia-reperfusion injury of rat livers J Hepatol 23 582 590 10.1016/0168-8278(95)80066-2 1:CAS:528:DyaK28Xjt12m 8583148
    • (1995) J Hepatol , vol.23 , pp. 582-590
    • Ono, T.1    Nagasue, N.2    Kohno, H.3    Uchida, M.4    Takemoto, Y.5    Dhar, D.K.6    Nakamura, T.7
  • 70
    • 23944504082 scopus 로고    scopus 로고
    • Enteral donor pre-treatment with ursodeoxycholic acid protects the liver against ischaemia-reperfusion injury in rats
    • DOI 10.1111/j.1432-2277.2004.tb00514.x
    • G Nowak UG Noren A Wernerson HU Marschall L Moller BG Ericzon 2005 Enteral donor pre-treatment with ursodeoxycholic acid protects the liver against ischaemia-reperfusion injury in rats Transpl Int 17 804 809 10.1111/j.1432-2277.2004.tb00514.x 1:CAS:528:DC%2BD2MXmvFSgur4%3D 15815896 (Pubitemid 41187421)
    • (2005) Transplant International , vol.17 , Issue.12 , pp. 804-809
    • Nowak, G.1    Noren, U.G.2    Wernerson, A.3    Marschall, H.-U.4    Moller, L.5    Ericzon, B.-G.6
  • 71
    • 34047101289 scopus 로고    scopus 로고
    • The effects of somatostatin and ursodeoxycholic acid in preventing the ischemic injury of the liver following Pringle maneuver in obstructive jaundice-rat model
    • 1:CAS:528:DC%2BD2sXks1aktro%3D 17419266
    • A Pergel K Zengin A Cercel H Aki S Kaya 2007 The effects of somatostatin and ursodeoxycholic acid in preventing the ischemic injury of the liver following Pringle maneuver in obstructive jaundice-rat model Hepatogastroenterology 54 229 233 1:CAS:528:DC%2BD2sXks1aktro%3D 17419266
    • (2007) Hepatogastroenterology , vol.54 , pp. 229-233
    • Pergel, A.1    Zengin, K.2    Cercel, A.3    Aki, H.4    Kaya, S.5
  • 72
    • 34147220621 scopus 로고    scopus 로고
    • Administration of Tauroursodeoxycholic Acid (TUDCA) reduces apoptosis following myocardial infarction in rat
    • DOI 10.1142/S0192415X07004813, PII S0192415X07004813
    • AL Rivard CJ Steer BT Kren CM Rodrigues RE Castro RW Bianco WC Low 2007 Administration of tauroursodeoxycholic acid (TUDCA) reduces apoptosis following myocardial infarction in rat Am J Chin Med 35 279 295 10.1142/S0192415X07004813 1:CAS:528:DC%2BD2sXktVOrs7c%3D 17436368 (Pubitemid 46579083)
    • (2007) American Journal of Chinese Medicine , vol.35 , Issue.2 , pp. 279-295
    • Rivard, A.L.1    Steer, C.J.2    Kren, B.T.3    Rodrigues, C.M.P.4    Castro, R.E.5    Bianco, R.W.6    Low, W.C.7
  • 73
    • 26844537040 scopus 로고    scopus 로고
    • Hydrophilic bile salt ursodeoxycholic acid protects myocardium against reperfusion injury in a PI3K/Akt dependent pathway
    • DOI 10.1016/j.yjmcc.2005.07.014, PII S0022282805002348
    • KG Rajesh R Suzuki H Maeda M Yamamoto X Yutong S Sasaguri 2005 Hydrophilic bile salt ursodeoxycholic acid protects myocardium against reperfusion injury in a PI3K/Akt dependent pathway J Mol Cell Cardiol 39 766 776 10.1016/j.yjmcc.2005.07.014 1:CAS:528:DC%2BD2MXhtFCjsLbO 16171810 (Pubitemid 41464413)
    • (2005) Journal of Molecular and Cellular Cardiology , vol.39 , Issue.5 , pp. 766-776
    • Rajesh, K.G.1    Suzuki, R.2    Maeda, H.3    Yamamoto, M.4    Yutong, X.5    Sasaguri, S.6
  • 74
    • 67649121818 scopus 로고    scopus 로고
    • Metallothionein alleviates oxidative stress-induced endoplasmic reticulum stress and myocardial dysfunction
    • 10.1016/j.yjmcc.2009.03.018 1:CAS:528:DC%2BD1MXnsl2itrY%3D 19344729
    • R Guo H Ma F Gao L Zhong J Ren 2009 Metallothionein alleviates oxidative stress-induced endoplasmic reticulum stress and myocardial dysfunction J Mol Cell Cardiol 47 228 237 10.1016/j.yjmcc.2009.03.018 1:CAS:528: DC%2BD1MXnsl2itrY%3D 19344729
    • (2009) J Mol Cell Cardiol , vol.47 , pp. 228-237
    • Guo, R.1    Ma, H.2    Gao, F.3    Zhong, L.4    Ren, J.5
  • 75
    • 0033203367 scopus 로고    scopus 로고
    • Effect of ursodeoxycholic acid on ischemia/reperfusion injury in isolated rat heart
    • 10.1007/BF02979156 1:CAS:528:DyaK1MXnt1Gqtbo%3D 10549575
    • WY Lee SH Han TS Cho YH Yoo SM Lee 1999 Effect of ursodeoxycholic acid on ischemia/reperfusion injury in isolated rat heart Arch Pharm Res 22 479 484 10.1007/BF02979156 1:CAS:528:DyaK1MXnt1Gqtbo%3D 10549575
    • (1999) Arch Pharm Res , vol.22 , pp. 479-484
    • Lee, W.Y.1    Han, S.H.2    Cho, T.S.3    Yoo, Y.H.4    Lee, S.M.5
  • 77
    • 0024990758 scopus 로고
    • Retinal degeneration in the rd mouse is caused by a defect in the β subunit of rod cGMP-phosphodiesterase
    • DOI 10.1038/347677a0
    • C Bowes T Li M Danciger LC Baxter ML Applebury DB Farber 1990 Retinal degeneration in the rd mouse is caused by a defect in the beta subunit of rod cGMP-phosphodiesterase Nature 347 677 680 10.1038/347677a0 1:CAS:528: DyaK3MXhsFKj 1977087 (Pubitemid 20356246)
    • (1990) Nature , vol.347 , Issue.6294 , pp. 677-680
    • Bowes, C.1    Li, T.2    Danciger, M.3    Baxter, L.C.4    Applebury, M.L.5    Farber, D.B.6
  • 78
    • 0036181472 scopus 로고    scopus 로고
    • Retinal degeneration mutants in the mouse
    • DOI 10.1016/S0042-6989(01)00146-8, PII S0042698901001468
    • B Chang NL Hawes RE Hurd MT Davisson S Nusinowitz JR Heckenlively 2002 Retinal degeneration mutants in the mouse Vision Res 42 517 525 10.1016/S0042-6989(01)00146-8 1:CAS:528:DC%2BD38Xhtlektrw%3D 11853768 (Pubitemid 34169709)
    • (2002) Vision Research , vol.42 , Issue.4 , pp. 517-525
    • Chang, B.1    Hawes, N.L.2    Hurd, R.E.3    Davisson, M.T.4    Nusinowitz, S.5    Heckenlively, J.R.6
  • 79
    • 33845592141 scopus 로고    scopus 로고
    • Retinal organization in the retinal degeneration 10 (rd10) mutant mouse: A morphological and ERG study
    • DOI 10.1002/cne.21144
    • C Gargini E Terzibasi F Mazzoni E Strettoi 2007 Retinal organization in the retinal degeneration 10 (rd10) mutant mouse: a morphological and ERG study J Comp Neurol 500 222 238 10.1002/cne.21144 17111372 (Pubitemid 44937119)
    • (2007) Journal of Comparative Neurology , vol.500 , Issue.2 , pp. 222-238
    • Gargini, C.1    Terzibasi, E.2    Mazzoni, F.3    Strettoi, E.4
  • 81
    • 33846145693 scopus 로고    scopus 로고
    • Tool from ancient pharmacopoeia prevents vision loss
    • 1:CAS:528:DC%2BD2sXnsFemsQ%3D%3D 17213800
    • JH Boatright, et al. 2006 Tool from ancient pharmacopoeia prevents vision loss Mol Vis 12 1706 1714 1:CAS:528:DC%2BD2sXnsFemsQ%3D%3D 17213800
    • (2006) Mol Vis , vol.12 , pp. 1706-1714
    • Boatright, J.H.1
  • 82
    • 44649159782 scopus 로고    scopus 로고
    • Tauroursodeoxycholic acid preservation of photoreceptor structure and function in the rd10 mouse through postnatal day 30
    • 10.1167/iovs.07-1012 18436848
    • MJ Phillips, et al. 2008 Tauroursodeoxycholic acid preservation of photoreceptor structure and function in the rd10 mouse through postnatal day 30 Invest Ophthalmol Vis Sci 49 2148 2155 10.1167/iovs.07-1012 18436848
    • (2008) Invest Ophthalmol Vis Sci , vol.49 , pp. 2148-2155
    • Phillips, M.J.1
  • 83
    • 76449113062 scopus 로고    scopus 로고
    • Chemical chaperones and TUDCA partially suppress degeneration of retinal photoreceptor cells in transgenic mutant rhodopsin S334ter-3 rats
    • E-Abstract 2038
    • Mulhern ML, Madson CJ, Thoreson W, Shinohara T. Chemical chaperones and TUDCA partially suppress degeneration of retinal photoreceptor cells in transgenic mutant rhodopsin S334ter-3 rats. Invest Ophthalmol Vis Sci. 2008;49:E-Abstract 2038.
    • (2008) Invest Ophthalmol Vis Sci. , pp. 49
    • Mulhern, M.L.1    Madson, C.J.2    Thoreson, W.3    Shinohara, T.4
  • 84
    • 33750169845 scopus 로고    scopus 로고
    • Transgenic rat models of inherited retinal degeneration caused by mutant opsin genes
    • RH Steinberg, et al. 1996 Transgenic rat models of inherited retinal degeneration caused by mutant opsin genes Invest Ophthalmol Vis Sci 37 S698
    • (1996) Invest Ophthalmol Vis Sci , vol.37 , pp. 698
    • Steinberg, R.H.1
  • 87
    • 0038750831 scopus 로고    scopus 로고
    • Increased expression of ceruloplasmin in the retina following photic injury
    • 1:CAS:528:DC%2BD3sXkvVCitrc%3D 12724641
    • L Chen T Dentchev R Wong P Hahn R Wen J Bennett JL Dunaief 2003 Increased expression of ceruloplasmin in the retina following photic injury Mol Vis 9 151 158 1:CAS:528:DC%2BD3sXkvVCitrc%3D 12724641
    • (2003) Mol Vis , vol.9 , pp. 151-158
    • Chen, L.1    Dentchev, T.2    Wong, R.3    Hahn, P.4    Wen, R.5    Bennett, J.6    Dunaief, J.L.7
  • 88
    • 0031664966 scopus 로고    scopus 로고
    • Apoptotic cell death in retinal degenerations
    • DOI 10.1016/S1350-9462(98)00009-3, PII S1350946298000093
    • CE Reme C Grimm F Hafezi A Marti A Wenzel 1998 Apoptotic cell death in retinal degenerations Prog Retin Eye Res 17 443 464 10.1016/S1350-9462(98)00009- 3 1:STN:280:DyaK1cvltVyhsw%3D%3D 9777646 (Pubitemid 28432977)
    • (1998) Progress in Retinal and Eye Research , vol.17 , Issue.4 , pp. 443-464
    • Reme, C.E.1    Grimm, C.2    Hafezi, F.3    Marti, A.4    Wenzel, A.5
  • 89
  • 90
    • 84945931814 scopus 로고    scopus 로고
    • Effect of tauroursodeoxycholic acid on mouse retinal ganglion cell degeneration following optic nerve transaction
    • E-Abstract 3180
    • Boatright, Boyd AP, Garcia-Valenzuela E. Effect of tauroursodeoxycholic acid on mouse retinal ganglion cell degeneration following optic nerve transection. Invest Ophthalmol Vis Sci. 2005;46:E-Abstract 3180.
    • (2005) Invest Ophthalmol Vis Sci. , pp. 46
    • Boatright1    Boyd, A.P.2    Garcia-Valenzuela, E.3
  • 91
    • 0031015439 scopus 로고    scopus 로고
    • Axon-mediated gene transfer of retinal ganglion cells in vivo
    • DOI 10.1002/(SICI)1097-4695(199701)32:1<111::AID-NEU10>3.0.CO;2-N
    • E Garcia-Valenzuela R Rayanade JC Perales CA Davidson RW Hanson SC Sharma 1997 Axon-mediated gene transfer of retinal ganglion cells in vivo J Neurobiol 32 111 122 10.1002/(SICI)1097-4695(199701)32:1<111::AID-NEU10>3.0.CO;2-N 1:CAS:528:DyaK2sXnvFentA%3D%3D 8989667 (Pubitemid 27020249)
    • (1997) Journal of Neurobiology , vol.32 , Issue.1 , pp. 111-122
    • Garcia-Valenzuela, E.1    Rayanade, R.2    Perales, J.C.3    Davidson, C.A.4    Hanson, R.W.5    Sharma, S.C.6
  • 92
    • 34547881945 scopus 로고    scopus 로고
    • Cellular osmolytes reduce lens epithelial cell death and alleviate cataract formation in galactosemic rats
    • 1:CAS:528:DC%2BD2sXhtV2gurjK 17768385
    • ML Mulhern CJ Madson PF Kador J Randazzo T Shinohara 2007 Cellular osmolytes reduce lens epithelial cell death and alleviate cataract formation in galactosemic rats Mol Vis 13 1397 1405 1:CAS:528:DC%2BD2sXhtV2gurjK 17768385
    • (2007) Mol Vis , vol.13 , pp. 1397-1405
    • Mulhern, M.L.1    Madson, C.J.2    Kador, P.F.3    Randazzo, J.4    Shinohara, T.5
  • 93
    • 47549111580 scopus 로고    scopus 로고
    • Effect of taurine-conjugated ursodeoxycholic acid on endoplasmic reticulum stress and apoptosis induced by advanced glycation end products in cultured mouse podocytes
    • 10.1159/000148209 1:CAS:528:DC%2BD1cXht1Slsb3K 18648192
    • Y Chen CP Liu KF Xu XD Mao YB Lu L Fang JW Yang C Liu 2008 Effect of taurine-conjugated ursodeoxycholic acid on endoplasmic reticulum stress and apoptosis induced by advanced glycation end products in cultured mouse podocytes Am J Nephrol 28 1014 1022 10.1159/000148209 1:CAS:528:DC%2BD1cXht1Slsb3K 18648192
    • (2008) Am J Nephrol , vol.28 , pp. 1014-1022
    • Chen, Y.1    Liu, C.P.2    Xu, K.F.3    Mao, X.D.4    Lu, Y.B.5    Fang, L.6    Yang, J.W.7    Liu, C.8
  • 95
    • 33748069813 scopus 로고    scopus 로고
    • Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes
    • DOI 10.1126/science.1128294
    • U Ozcan E Yilmaz L Ozcan M Furuhashi E Vaillancourt RO Smith CZ Gorgun GS Hotamisligil 2006 Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes Science 313 1137 1140 10.1126/science.1128294 16931765 (Pubitemid 44300242)
    • (2006) Science , vol.313 , Issue.5790 , pp. 1137-1140
    • Ozcan, U.1    Yilmaz, E.2    Ozcan, L.3    Furuhashi, M.4    Vaillancourt, E.5    Smith, R.O.6    Gorgun, C.Z.7    Hotamisligil, G.S.8
  • 96
    • 0036725164 scopus 로고    scopus 로고
    • Effect of tauroursodeoxycholic acid on endoplasmic reticulum stress-induced caspase-12 activation
    • DOI 10.1053/jhep.2002.35441
    • Q Xie VI Khaoustov CC Chung J Sohn B Krishnan DE Lewis B Yoffe 2002 Effect of tauroursodeoxycholic acid on endoplasmic reticulum stress-induced caspase-12 activation Hepatology 36 592 601 10.1053/jhep.2002.35441 1:CAS:528:DC%2BD38XnvVSkt7k%3D 12198651 (Pubitemid 34977169)
    • (2002) Hepatology , vol.36 , Issue.3 , pp. 592-601
    • Xie, Q.1    Khaoustov, V.I.2    Chung, C.C.3    Sohn, J.4    Krishnan, B.5    Lewis, D.E.6    Yoffe, B.7
  • 97
    • 76449113801 scopus 로고    scopus 로고
    • Chemical chaperones and bile acids protect molecular chaperones, alpha-crystallins against thermal denaturation in vitro
    • E-Abstract 4504
    • Shinohara T, Liang J, Song S, Mulhern ML, Thurston G. Chemical chaperones and bile acids protect molecular chaperones, alpha-crystallins against thermal denaturation in vitro. Invest Ophthalmol Vis Sci. 2008;49:E-Abstract 4504.
    • (2008) Invest Ophthalmol Vis Sci. , pp. 49
    • Shinohara, T.1    Liang, J.2    Song, S.3    Mulhern, M.L.4    Thurston, G.5
  • 98
    • 38049109883 scopus 로고    scopus 로고
    • Ursodeoxycholic acid: Mechanism of action and novel clinical applications
    • 1:CAS:528:DC%2BD1cXptlWqtLk%3D 18034825
    • T Ikegami Y Matsuzaki 2008 Ursodeoxycholic acid: mechanism of action and novel clinical applications Hepatol Res 38 123 131 1:CAS:528: DC%2BD1cXptlWqtLk%3D 18034825
    • (2008) Hepatol Res , vol.38 , pp. 123-131
    • Ikegami, T.1    Matsuzaki, Y.2
  • 100
    • 55349129960 scopus 로고    scopus 로고
    • Taurine suppresses the spread of cell death in electrically coupled RPE cells
    • 1:CAS:528:DC%2BD1cXhsVaqu73O 18958305
    • C Udawatte H Qian NJ Mangini BG Kennedy H Ripps 2008 Taurine suppresses the spread of cell death in electrically coupled RPE cells Mol Vis 14 1940 1950 1:CAS:528:DC%2BD1cXhsVaqu73O 18958305
    • (2008) Mol Vis , vol.14 , pp. 1940-1950
    • Udawatte, C.1    Qian, H.2    Mangini, N.J.3    Kennedy, B.G.4    Ripps, H.5


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