Tauroursodeoxycholic acid modulates p53-mediated apoptosis in Alzheimer's disease mutant neuroblastoma cells

Journal of Neurochemistry

Volumn 98, Issue 5, 2006, Pages 1610-1618

  Ramalho, Rita M ^a   Borralho, Pedro M ^a   Castro, Rui E ^a   Solá, Susana ^a   Steer, Clifford J ^b   Rodrigues, Cecília M P ^a,c  

^a UNIVERSITY OF LISBON   (Portugal)

^b UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^c NONE   (Portugal)

Author keywords

Amyloid peptide; Apoptosis; Bile acids; Familial Alzheimer's disease; Neuroprotection

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; CARBONYL DERIVATIVE; CASPASE 2; CASPASE 6; CASPASE 8; PHOSPHATIDYLINOSITIDE 3' HYDROXIDE KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOTRANSFERASE; PRESENILIN 1; PRESENILIN 2; PROTEIN BAX; PROTEIN P53; TAUROURSODEOXYCHOLIC ACID; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; APOPTOSIS; ARTICLE; CELL DEATH; CELL VIABILITY; CONTROLLED STUDY; ENZYME ACTIVATION; GENE MUTATION; HUMAN; HUMAN CELL; NEUROBLASTOMA; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN SYNTHESIS;

ALZHEIMER DISEASE; AMINO ACID CHLOROMETHYL KETONES; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; ANTIVIRAL AGENTS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BLOTTING, WESTERN; CASPASES; CELL LINE, TUMOR; CYSTEINE PROTEINASE INHIBITORS; ENZYME ACTIVATION; HUMANS; IN SITU NICK-END LABELING; MEMBRANE PROTEINS; MICE; MUTATION; NEUROBLASTOMA; PRESENILIN-1; PRESENILIN-2; PROTO-ONCOGENE PROTEINS C-BCL-2; TAUROCHENODEOXYCHOLIC ACID; TRANSFECTION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 33746862168     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2006.04007.x     Document Type: Article

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