메뉴 건너뛰기




Volumn 50, Issue 2, 2010, Pages 132-139

Hemin exerts multiple protective mechanisms and attenuates dextran sulfate sodium-induced colitis

Author keywords

Colitis; Inflammatory bowel disease; Interleukin 17; Regulatory T cells

Indexed keywords

DEXTRAN SULFATE; HEME OXYGENASE 1; HEMIN; INTERLEUKIN 17; PROTOPORPHYRIN TIN; TRANSCRIPTION FACTOR FOXP3;

EID: 76349114510     PISSN: 02772116     EISSN: None     Source Type: Journal    
DOI: 10.1097/MPG.0b013e3181c61591     Document Type: Article
Times cited : (48)

References (61)
  • 1
    • 0142053206 scopus 로고    scopus 로고
    • The immunological and genetic basis of inflammatory bowel disease
    • Bouma G, Strober W. The immunological and genetic basis of inflammatory bowel disease. Nat Rev Immunol 2003;7:521-533
    • (2003) Nat Rev Immunol , vol.7 , pp. 521-533
    • Bouma, G.1    Strober, W.2
  • 2
    • 0037043658 scopus 로고    scopus 로고
    • Inflammatory bowel disease
    • Podolsky DK. Inflammatory bowel disease. N Engl J Med 2002;347: 417-429
    • (2002) N Engl J Med , vol.347 , pp. 417-429
    • Podolsky, D.K.1
  • 3
    • 0034037623 scopus 로고    scopus 로고
    • The importance of clinicopathological correlation in the diagnosis of inflammatory conditions of the colon: Histological patterns with clinical implications
    • Carpenter HA, Talley NJ. The importance of clinicopathological correlation in the diagnosis of inflammatory conditions of the colon: histological patterns with clinical implications. Am J Gastroenterol 2000;95:878-896
    • (2000) Am J Gastroenterol , vol.95 , pp. 878-896
    • Carpenter, H.A.1    Talley, N.J.2
  • 4
    • 33845340501 scopus 로고    scopus 로고
    • A genome-wide association study identifies IL23R as an inflammatory bowel disease gene
    • Duerr RH, Taylor KD, Brant SR, et al. A genome-wide association study identifies IL23R as an inflammatory bowel disease gene. Science 2006;314:1461-1463
    • (2006) Science , vol.314 , pp. 1461-1463
    • Duerr, R.H.1    Taylor, K.D.2    Brant, S.R.3
  • 6
    • 34047139587 scopus 로고    scopus 로고
    • Inflammatory bowel disease genetics: Nod2
    • Cho JH, Abraham C. Inflammatory bowel disease genetics: Nod2. Annu Rev Med 2007;58:401-416
    • (2007) Annu Rev Med , vol.58 , pp. 401-416
    • Cho, J.H.1    Abraham, C.2
  • 7
    • 76349109589 scopus 로고    scopus 로고
    • Essential autocrine regulation by IL-21 in the generation of inflammatory T cells
    • Nurieva R, Yang XO, Martinez G, et al. Essential autocrine regulation by IL-21 in the generation of inflammatory T cells. Nature 2007;441: 231-234
    • (2007) Nature , vol.441 , pp. 231-234
    • Nurieva, R.1    Yang, X.O.2    Martinez, G.3
  • 8
    • 34547188748 scopus 로고    scopus 로고
    • IL-6 programs Th-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways
    • Zhou L, Ivanov II, Spolski R, et al. IL-6 programs Th-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways. Nat Immunol 2007;8:967-974
    • (2007) Nat Immunol , vol.8 , pp. 967-974
    • Zhou, L.1    Ivanov, I.I.2    Spolski, R.3
  • 10
    • 0037299902 scopus 로고    scopus 로고
    • Upregulation of interleukin-12 and -17 in active inflammatory bowel disease
    • Nielsen OH, Kirman I, Rüdiger N, et al. Upregulation of interleukin-12 and -17 in active inflammatory bowel disease. Scand J Gastroenterol 2003;38:180-185
    • (2003) Scand J Gastroenterol , vol.38 , pp. 180-185
    • Nielsen, O.H.1    Kirman, I.2    Rüdiger, N.3
  • 11
    • 33646804892 scopus 로고    scopus 로고
    • Critical role of IL-17 receptor signaling in acute TNBS-induced colitis
    • Zhang Z, Zheng M,Bindas J, et al. Critical role of IL-17 receptor signaling in acute TNBS-induced colitis. Inflamm Bowel Dis 2006;12:382-388
    • (2006) Inflamm Bowel Dis , vol.12 , pp. 382-388
    • Zhang, Z.1    Zheng, M.2    Bindas, J.3
  • 12
    • 33847008328 scopus 로고    scopus 로고
    • After interleukin-12p40, are interleukin-23 and interleukin-17 the next therapeutic targets for inflammatory bowel disease?
    • Zhang Z, Hinrichs DJ, Lu H, et al. After interleukin-12p40, are interleukin-23 and interleukin-17 the next therapeutic targets for inflammatory bowel disease? Int Immunopharmacol 2007;7:409-416
    • (2007) Int Immunopharmacol , vol.7 , pp. 409-416
    • Zhang, Z.1    Hinrichs, D.J.2    Lu, H.3
  • 13
    • 4644275197 scopus 로고    scopus 로고
    • Regulatory T cells: Peace keepers in the gut
    • Allez M, Mayer L. Regulatory T cells: peace keepers in the gut. Inflamm Bowel Dis 2004;10:666-676
    • (2004) Inflamm Bowel Dis , vol.10 , pp. 666-676
    • Allez, M.1    Mayer, L.2
  • 14
    • 34147196190 scopus 로고    scopus 로고
    • Immunopathogenesis of IBD: Insufficient suppressor function in the gut?
    • Huibregtse IL, Van Lent AU, Van Deventer SJ. Immunopathogenesis of IBD: insufficient suppressor function in the gut? Gut 2007;56:584-592
    • (2007) Gut , vol.56 , pp. 584-592
    • Huibregtse, I.L.1    Van Lent, A.U.2    Van Deventer, S.J.3
  • 15
    • 39449126502 scopus 로고    scopus 로고
    • The Foxp3+ regulatory T cell: A jack of all trades, master of regulation
    • Tang Q, Bluestone JA. The Foxp3+ regulatory T cell: a jack of all trades, master of regulation. Nat Immunol 2008;9:239-244
    • (2008) Nat Immunol , vol.9 , pp. 239-244
    • Tang, Q.1    Bluestone, J.A.2
  • 16
    • 34249309861 scopus 로고    scopus 로고
    • Expression and functional characterization of FOXP3+ CD4+ regulatory T cells in ulcerative colitis
    • Yu QT, Saruta M, Avanesyan A, et al. Expression and functional characterization of FOXP3+ CD4+ regulatory T cells in ulcerative colitis. Inflamm Bowel Dis 2007;13:191-199
    • (2007) Inflamm Bowel Dis , vol.13 , pp. 191-199
    • Yu, Q.T.1    Saruta, M.2    Avanesyan, A.3
  • 17
    • 20444434616 scopus 로고    scopus 로고
    • Peripheral and intestinal regulatory CD4+ CD25(high) T cells in inflammatory bowel disease
    • Maul J, Loddenkemper C, Mundt P, et al. Peripheral and intestinal regulatory CD4+ CD25(high) T cells in inflammatory bowel disease. Gastroenterology 2005;128:1868-1878.
    • (2005) Gastroenterology , vol.128 , pp. 1868-1878
    • Maul, J.1    Loddenkemper, C.2    Mundt, P.3
  • 18
    • 42049110786 scopus 로고    scopus 로고
    • The role of heme oxygenase-1 in T cell-mediated immunity: The all encompassing enzyme
    • XiaZW, ZhongWW, Meyrowitz JS, et al. The role of heme oxygenase-1 in T cell-mediated immunity: the all encompassing enzyme. Curr Pharm Des 2008;14:454-464
    • (2008) Curr Pharm des , vol.14 , pp. 454-464
    • Xia, Z.W.1    Zhong, W.W.2    Meyrowitz, J.S.3
  • 19
    • 61449417240 scopus 로고    scopus 로고
    • Heme oxygenase-1 and carbon monoxide: Emerging therapeutic targets in inflammation and allergy
    • Pae HO, Lee YC, Chung HT. Heme oxygenase-1 and carbon monoxide: emerging therapeutic targets in inflammation and allergy. Recent Pat Inflamm Allergy Drug Discov 2008;2:159-165
    • (2008) Recent Pat Inflamm Allergy Drug Discov , vol.2 , pp. 159-165
    • Pae, H.O.1    Lee, Y.C.2    Chung, H.T.3
  • 20
    • 4644226200 scopus 로고    scopus 로고
    • The role of heme oxygenase-1 promoter polymorphisms in human disease
    • Exner M, Minar E, Wagner O, et al. The role of heme oxygenase-1 promoter polymorphisms in human disease. Free Radic Biol Med 2004;37:1097-1104
    • (2004) Free Radic Biol Med , vol.37 , pp. 1097-1104
    • Exner, M.1    Minar, E.2    Wagner, O.3
  • 21
    • 4243550127 scopus 로고    scopus 로고
    • Heme oxygenase/carbon monoxide signaling pathways: Regulation and functional significance
    • Ryter SW, Otterbein LE, Morse D, et al. Heme oxygenase/carbon monoxide signaling pathways: regulation and functional significance. Mol Cell Biochem 2002;234-235:249-263
    • (2002) Mol Cell Biochem , vol.234-235 , pp. 249-263
    • Ryter, S.W.1    Otterbein, L.E.2    Morse, D.3
  • 23
    • 46749110831 scopus 로고    scopus 로고
    • Suppression by CD4+CD25+ regulatory T cells is dependent on expression of heme oxygenase-1 in antigen-presenting cells
    • George JF, Braun A, Brusko TM, et al. Suppression by CD4+CD25+ regulatory T cells is dependent on expression of heme oxygenase-1 in antigen-presenting cells. Am J Pathol 2008;173:154-160
    • (2008) Am J Pathol , vol.173 , pp. 154-160
    • George, J.F.1    Braun, A.2    Brusko, T.M.3
  • 24
    • 33750375087 scopus 로고    scopus 로고
    • Heme oxygenase-1-mediated CD4+CD25high regulatory T cells suppress allergic airway inflammation
    • Xia ZW, Zhong WW, Xu LQ, et al. Heme oxygenase-1-mediated CD4+CD25high regulatory T cells suppress allergic airway inflammation. J Immunol 2006;177:5936-5945
    • (2006) J Immunol , vol.177 , pp. 5936-5945
    • Xia, Z.W.1    Zhong, W.W.2    Xu, L.Q.3
  • 25
    • 0012151673 scopus 로고
    • Dual control mechanism for heme oxygenase: Tin(IV)-protoporphyrin potently inhibits enzyme activity while markedly increasing content of enzyme protein in liver
    • Sardana MK, Kappas A. Dual control mechanism for heme oxygenase: tin(IV)-protoporphyrin potently inhibits enzyme activity while markedly increasing content of enzyme protein in liver. Proc Natl Acad Sci 1987;84:2464-2468
    • (1987) Proc Natl Acad Sci , vol.84 , pp. 2464-2468
    • Sardana, M.K.1    Kappas, A.2
  • 26
    • 43549099743 scopus 로고    scopus 로고
    • The interleukin-23/interleukin-17 axis in intestinal inflammation
    • Maloy KJ. The interleukin-23/interleukin-17 axis in intestinal inflammation. J Intern Med 2008;263:584-590
    • (2008) J Intern Med , vol.263 , pp. 584-590
    • Maloy, K.J.1
  • 27
    • 55149112367 scopus 로고    scopus 로고
    • The interleukin-23 axis in intestinal inflammation
    • Ahern PP, Izcue A, Maloy KJ, et al. The interleukin-23 axis in intestinal inflammation. Immunol Rev 2008;226:147-159
    • (2008) Immunol Rev , vol.226 , pp. 147-159
    • Ahern, P.P.1    Izcue, A.2    Maloy, K.J.3
  • 29
    • 33646761325 scopus 로고    scopus 로고
    • Heme oxygenase-1 and transplantation tolerance
    • Bach FH. Heme oxygenase-1 and transplantation tolerance. Hum Immunol 2006;67:430-432
    • (2006) Hum Immunol , vol.67 , pp. 430-432
    • Bach, F.H.1
  • 30
    • 34547686232 scopus 로고    scopus 로고
    • Heme oxygenase-1 in organ transplantation
    • Soares MP, Bach FH. Heme oxygenase-1 in organ transplantation. Front Biosci 2007;12:4932-4945
    • (2007) Front Biosci , vol.12 , pp. 4932-4945
    • Soares, M.P.1    Bach, F.H.2
  • 31
    • 33846819008 scopus 로고    scopus 로고
    • Heme oxygenase-1 and carbon monoxide suppress autoimmune neuroinflammation
    • Chora AA, Fontoura P, Cunha A, et al. Heme oxygenase-1 and carbon monoxide suppress autoimmune neuroinflammation. J Clin Invest 2007;117:438-447
    • (2007) J Clin Invest , vol.117 , pp. 438-447
    • Chora, A.A.1    Fontoura, P.2    Cunha, A.3
  • 32
    • 27644433355 scopus 로고    scopus 로고
    • Role of regulatory T cells in human diseases
    • Chatila TA. Role of regulatory T cells in human diseases. J Allergy Clin Immunol 2005;116:949-959
    • (2005) J Allergy Clin Immunol , vol.116 , pp. 949-959
    • Chatila, T.A.1
  • 33
    • 27144495833 scopus 로고    scopus 로고
    • How do CD4+CD25+ regulatory T cells control autoimmunity?
    • Bluestone JA, Tang Q. How do CD4+CD25+ regulatory T cells control autoimmunity? Curr Opin Immunol 2005;17:638-642
    • (2005) Curr Opin Immunol , vol.17 , pp. 638-642
    • Bluestone, J.A.1    Tang, Q.2
  • 34
    • 0344585384 scopus 로고    scopus 로고
    • Suppression of immune induction of collagen-induced arthritis in IL-17-deficient mice
    • Nakae S, Nambu A, Sudo K, et al. Suppression of immune induction of collagen-induced arthritis in IL-17-deficient mice. J Immunol 2003;171: 6173-6177
    • (2003) J Immunol , vol.171 , pp. 6173-6177
    • Nakae, S.1    Nambu, A.2    Sudo, K.3
  • 35
    • 0038623916 scopus 로고    scopus 로고
    • IL-17 production from activated T cells is required for the spontaneous development of destructive arthritis in mice deficient in IL-1 receptor antagonist
    • Nakae S, Saijo S, Horai R, et al. IL-17 production from activated T cells is required for the spontaneous development of destructive arthritis in mice deficient in IL-1 receptor antagonist. Proc Natl Acad Sci U S A 2003;100:5986-5990
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 5986-5990
    • Nakae, S.1    Saijo, S.2    Horai, R.3
  • 36
    • 76349117116 scopus 로고    scopus 로고
    • IL-17 is produced by nickel-specific T lymphocytes and regulates ICAM-1 expression and chemokine production in human keratinocytes: Synergistic or antagonist effects with IFNgamma and TNF-alpha
    • Albanesi C, Cavani A, Girolomoni G. IL-17 is produced by nickel-specific T lymphocytes and regulates ICAM-1 expression and chemokine production in human keratinocytes: synergistic or antagonist effects with IFNgamma and TNF-alpha. J Immunol 1999;103:1345-1352
    • (1999) J Immunol , vol.103 , pp. 1345-1352
    • Albanesi, C.1    Cavani, A.2    Girolomoni, G.3
  • 37
    • 47249125726 scopus 로고    scopus 로고
    • Chronically inflamed human tissues are infiltrated by highly differentiated Th17 lymphocytes
    • Pène J, Chevalier S, Preisser L, et al. Chronically inflamed human tissues are infiltrated by highly differentiated Th17 lymphocytes. J Immunol 2008;180:7423-7430
    • (2008) J Immunol , vol.180 , pp. 7423-7430
    • Pène, J.1    Chevalier, S.2    Preisser, L.3
  • 38
    • 33846412586 scopus 로고    scopus 로고
    • Interaction between interleukin-17- producing CD4+ T cells and colonic subepithelial myofibroblasts: What are they doing in mucosal inflammation?
    • Andoh A, Ogawa A, Bamba S, et al. Interaction between interleukin-17- producing CD4+ T cells and colonic subepithelial myofibroblasts: what are they doing in mucosal inflammation? J Gastroenterol 2007;42 (Suppl 17):29-33.
    • (2007) J Gastroenterol , vol.42 , Issue.SUPPL. 17 , pp. 29-33
    • Andoh, A.1    Ogawa, A.2    Bamba, S.3
  • 39
    • 5644277476 scopus 로고    scopus 로고
    • Interleukin-17 family members and inflammation
    • Kolls JK, Lindén A. Interleukin-17 family members and inflammation. Immunity 2004;21:467-476
    • (2004) Immunity , vol.21 , pp. 467-476
    • Kolls, J.K.1    Lindén, A.2
  • 40
    • 43449135305 scopus 로고    scopus 로고
    • TGF-beta-induced Foxp3 inhibits T(H)17 cell differentiation by antagonizing RORgammat function
    • Zhou L, Lopes JE, Chong MM, et al. TGF-beta-induced Foxp3 inhibits T(H)17 cell differentiation by antagonizing RORgammat function. Nature 2008;453:236-240
    • (2008) Nature , vol.453 , pp. 236-240
    • Zhou, L.1    Lopes, J.E.2    Chong, M.M.3
  • 41
    • 45149109643 scopus 로고    scopus 로고
    • In vivo equilibrium of proinflammatory IL-17+ and regulatory IL-10+ Foxp3+ ROR{gamma}t+ T cells
    • Lochner M, Peduto L, Cherrier M, et al. In vivo equilibrium of proinflammatory IL-17+ and regulatory IL-10+ Foxp3+ ROR{gamma}t+ T cells. J Exp Med 2008;205:1381-1393
    • (2008) J Exp Med , vol.205 , pp. 1381-1393
    • Lochner, M.1    Peduto, L.2    Cherrier, M.3
  • 42
    • 44449131480 scopus 로고    scopus 로고
    • Isoform-specific inhibition of ROR {alpha}-mediated transcriptional activation by human FOXP3
    • Du J, Huang C, Zhou B, et al. Isoform-specific inhibition of ROR {alpha}-mediated transcriptional activation by human FOXP3. J Immunol 2008;180:4785-4792
    • (2008) J Immunol , vol.180 , pp. 4785-4792
    • Du, J.1    Huang, C.2    Zhou, B.3
  • 43
    • 47049114262 scopus 로고    scopus 로고
    • Epstein-Barr virus-induced gene 3 negatively regulates IL-17, IL-22 and RORgamma t
    • Yang J, Yang M, Htut TM, et al. Epstein-Barr virus-induced gene 3 negatively regulates IL-17, IL-22 and RORgamma t. Eur J Immunol 2008;38:1204-1214
    • (2008) Eur J Immunol , vol.38 , pp. 1204-1214
    • Yang, J.1    Yang, M.2    Htut, T.M.3
  • 44
    • 55149126024 scopus 로고    scopus 로고
    • Regulation of immune responses by interleukin-27
    • Yoshida H, Yoshiyuki M. Regulation of immune responses by interleukin-27. Immunol Rev 2008;226:234-247
    • (2008) Immunol Rev , vol.226 , pp. 234-247
    • Yoshida, H.1    Yoshiyuki, M.2
  • 45
    • 56249143761 scopus 로고    scopus 로고
    • From the diet to the nucleus: Vitamin A and TGF-beta join efforts at the mucosal interface of the intestine
    • Mucida D, Park Y, Cheroutre H. From the diet to the nucleus: vitamin A and TGF-beta join efforts at the mucosal interface of the intestine. Semin Immunol 2009;21:14-21.
    • (2009) Semin Immunol , vol.21 , pp. 14-21
    • Mucida, D.1    Park, Y.2    Cheroutre, H.3
  • 46
    • 39449101603 scopus 로고    scopus 로고
    • Transcriptional regulation of Th17 cell differentiation
    • Ivanov II, Zhou L, Littman DR. Transcriptional regulation of Th17 cell differentiation. Semin Immunol 2007;19:409-417
    • (2007) Semin Immunol , vol.19 , pp. 409-417
    • Ivanov, I.I.1    Zhou, L.2    Littman, D.R.3
  • 47
    • 23344449020 scopus 로고    scopus 로고
    • Experimental models of inflammatory bowel disease reveal innate, adaptive, and regulatory mechanisms of host dialogue with the microbiota
    • Elson CO, Cong Y, McCracken VJ, et al. Experimental models of inflammatory bowel disease reveal innate, adaptive, and regulatory mechanisms of host dialogue with the microbiota. Immunol Rev 2005;206:260-276
    • (2005) Immunol Rev , vol.206 , pp. 260-276
    • Elson, C.O.1    Cong, Y.2    Mc Cracken, V.J.3
  • 48
    • 33144485558 scopus 로고    scopus 로고
    • Role of interleukin 15 in colitis induced by dextran sulphate sodium in mice
    • Yoshihara K, Yajima T, Kubo C, et al. Role of interleukin 15 in colitis induced by dextran sulphate sodium in mice. Gut 2006;55:334-341
    • (2006) Gut , vol.55 , pp. 334-341
    • Yoshihara, K.1    Yajima, T.2    Kubo, C.3
  • 49
    • 0032168626 scopus 로고    scopus 로고
    • + T cells in the development of dextran sulfate sodium-induced experimental colitis and suppressive effect of IgG on their action
    • DOI 10.1016/S0306-3623(98)00004-4, PII S0306362398000044
    • Shintani N, Nakajima T, Okamoto T, et al. Involvement of CD4+ T cells in the development of dextran sulfate sodium-induced experimental colitis and suppressive effect of IgG on their action. Gen Pharmacol 1998;31:477-481 (Pubitemid 28398878)
    • (1998) General Pharmacology , vol.31 , Issue.3 , pp. 477-481
    • Shintani, N.1    Nakajima, T.2    Okamoto, T.3    Kondo, T.4    Nakamura, N.5    Mayumi, T.6
  • 50
    • 33750815930 scopus 로고    scopus 로고
    • CD8+ IL-17-producing T cells are important in effector functions for the elicitation of contact hypersensitivity responses
    • He D, Wu L, Kim HK, et al. CD8+ IL-17-producing T cells are important in effector functions for the elicitation of contact hypersensitivity responses. J Immunol 2006;177:6852-6858
    • (2006) J Immunol , vol.177 , pp. 6852-6858
    • He, D.1    Wu, L.2    Kim, H.K.3
  • 51
    • 34249059942 scopus 로고    scopus 로고
    • Identification of an IL-17- Producing NK1.1(neg) iNKT cell population involved in airway neutrophilia
    • Michel ML, Keller AC, Paget C, et al. Identification of an IL-17- producing NK1.1(neg) iNKT cell population involved in airway neutrophilia. J Exp Med 2007;204:995-1001.
    • (2007) J Exp Med , vol.204 , pp. 995-1001
    • Michel, M.L.1    Keller, A.C.2    Paget, C.3
  • 53
    • 33947677787 scopus 로고    scopus 로고
    • Resident Vdelta1+ gammadelta T cells control early infiltration of neutrophils after Escherichia coli infection via IL-17 production
    • Shibata K, Yamada H, Hara H, et al. Resident Vdelta1+ gammadelta T cells control early infiltration of neutrophils after Escherichia coli infection via IL-17 production. J Immunol 2007;178:4466-4472
    • (2007) J Immunol , vol.178 , pp. 4466-4472
    • Shibata, K.1    Yamada, H.2    Hara, H.3
  • 54
    • 58749116295 scopus 로고    scopus 로고
    • Identification of CD25+ gamma delta T cells as fetal thymus-derived naturally occurring IL-17 producers
    • Shibata K, Yamada H, Nakamura R, et al. Identification of CD25+ gamma delta T cells as fetal thymus-derived naturally occurring IL-17 producers. J Immunol 2008;181:5940-5947
    • (2008) J Immunol , vol.181 , pp. 5940-5947
    • Shibata, K.1    Yamada, H.2    Nakamura, R.3
  • 55
    • 33646801637 scopus 로고    scopus 로고
    • Regulation of apoptosis during homeostasis and disease in the intestinal epithelium
    • Edelblum KL, Yan F, Yamaoka T, et al. Regulation of apoptosis during homeostasis and disease in the intestinal epithelium. Inflamm Bowel Dis 2006;12:413-424
    • (2006) Inflamm Bowel Dis , vol.12 , pp. 413-424
    • Edelblum, K.L.1    Yan, F.2    Yamaoka, T.3
  • 56
    • 67249152713 scopus 로고    scopus 로고
    • Epithelial tight junctions in intestinal inflammation
    • Schulzke JD, Ploeger S, Amasheh M, et al. Epithelial tight junctions in intestinal inflammation. Ann N Y Acad Sci 2009;1165:294-300.
    • (2009) Ann N y Acad Sci , vol.1165 , pp. 294-300
    • Schulzke, J.D.1    Ploeger, S.2    Amasheh, M.3
  • 57
    • 61949472508 scopus 로고    scopus 로고
    • Innate immune recognition of infected apoptotic cells directs Th17 cell differentiation
    • Torchinsky MB, Garaude J, Martin AP, et al. Innate immune recognition of infected apoptotic cells directs Th17 cell differentiation. Nature 2009;458:78-82.
    • (2009) Nature , vol.458 , pp. 78-82
    • Torchinsky, M.B.1    Garaude, J.2    Martin, A.P.3
  • 58
    • 68049091014 scopus 로고    scopus 로고
    • Mouse dendritic cells matured by ingestion of apoptotic blebs induce T cells to produce interleukin-17
    • Fransen JH, Hilbrands LB, Ruben J, et al. Mouse dendritic cells matured by ingestion of apoptotic blebs induce T cells to produce interleukin-17. Arthritis Rheum 2009;60:2304-2313
    • (2009) Arthritis Rheum , vol.60 , pp. 2304-2313
    • Fransen, J.H.1    Hilbrands, L.B.2    Ruben, J.3
  • 59
    • 29144489192 scopus 로고    scopus 로고
    • Carbon monoxide ameliorates chronic murine colitis through a heme oxygenase 1-dependent pathway
    • Hegazi RA, Rao KN, Mayle A, et al. Carbon monoxide ameliorates chronic murine colitis through a heme oxygenase 1-dependent pathway. J Exp Med 2005;202:1703-1713
    • (2005) J Exp Med , vol.202 , pp. 1703-1713
    • Hegazi, R.A.1    Rao, K.N.2    Mayle, A.3
  • 60
    • 17444423274 scopus 로고    scopus 로고
    • Heme oxygenase-1- Generated biliverdin ameliorates experimental murine colitis
    • Berberat PO, A-Rahim YI, Yamashita K, et al. Heme oxygenase-1- generated biliverdin ameliorates experimental murine colitis. Inflamm Bowel Dis 2005;11:350-359
    • (2005) Inflamm Bowel Dis , vol.11 , pp. 350-359
    • Berberat, P.O.1    A-Rahim, Y.I.2    Yamashita, K.3
  • 61
    • 0034880733 scopus 로고    scopus 로고
    • Protective role of heme oxygenase-1 on trinitrobenzene sulfonic acid-induced colitis in rats
    • Wang WP, Guo X, Koo MW, et al. Protective role of heme oxygenase-1 on trinitrobenzene sulfonic acid-induced colitis in rats. Am J Physiol Gastrointest Liver Physiol 2001;281:G586-94.
    • (2001) Am J Physiol Gastrointest Liver Physiol , vol.281
    • Wang, W.P.1    Guo, X.2    Koo, M.W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.