Role of interleukin 15 in colitis induced by dextran sulphate sodium in mice

Gut

Volumn 55, Issue 3, 2006, Pages 334-341

  Yoshihara, K ^a   Yajima, Toshiki ^a   Kubo, C ^b   Yoshikai, Y ^a  

^a KYUSHU UNIVERSITY   (Japan)

^b KYUSHU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DEXTRAN SULFATE; GAMMA INTERFERON; HERMES ANTIGEN; INTERLEUKIN 12P40; INTERLEUKIN 15; TUMOR NECROSIS FACTOR ALPHA;

ACUTE DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CD8+ T LYMPHOCYTE; CHRONIC DISEASE; COLITIS; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE ACTIVITY; KNOCKOUT MOUSE; LAMINA PROPRIA; LEUKOCYTE COUNT; LYMPHOCYTE DEPLETION; MOUSE; NATURAL KILLER CELL; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; SURVIVAL RATE; TISSUE INJURY; WEIGHT REDUCTION;

ACUTE DISEASE; ANIMALS; CHRONIC DISEASE; COLITIS; COLON; CYTOKINES; DEXTRAN SULFATE; DISEASE MODELS, ANIMAL; INTERLEUKIN-15; INTESTINAL MUCOSA; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; SURVIVAL RATE; WEIGHT LOSS;

EID: 33144485558     PISSN: 00175749     EISSN: None     Source Type: Journal    
DOI: 10.1136/gut.2005.076000     Document Type: Article

References (52)

1. Fiocchi C. Inflammatory bowel disease: etiology and pathogenesis. Gastroenterology 1998;115:182-205.
2. McKay DM. Intestinal inflammation and the gut microflora. Can J Gastroenterol 1999;13:509-16.
3. Sartor RB. The influence of normal microbial flora on the development of chronic mucosal inflammation. Res Immunol 1997;148:567-76.
4. Cong Y, Brandwein SL, McCabe RP, et al. CD4+ T cells reactive to enteric bacterial antigens in spontaneously colitic C3H/HeJBir mice: increased T helper cell type 1 response and ability to transfer disease. J Exp Med 1998;187:855-64.
5. Maaser C, Kagnoff MF. Role of the intestinal epithelium in orchestrating innate and adaptive mucosal immunity. Z Gastroenterol 2002;40:525-9.
6. Reinecker HC, Steffen M, Witthoeft T, et al. Enhanced secretion of tumour necrosis factor-alpha, IL-6, and IL-1 beta by isolated lamina propria mononuclear cells from patients with ulcerative colitis and Crohn's disease. Clin Exp Immunol 1993;94:174-81.
7. Fuss U, Neurath M, Boirivant M, et al. Disparate CD4+ lamina propria (LP) lymphokine secretion profiles in inflammatory bowel disease. Crohn's disease LP cells manifest increased secretion of IFN-gamma, whereas ulcerative colitis LP cells manifest increased secretion of IL-5. J Immunol 1996;157:1261-70.
8. Braegger CP, MacDonald TT. Immune mechanisms in chronic inflammatory bowel disease. Ann Allergy 1994;72:135-41.
9. Monteleone G, Biancone L, Marasco R, et al. Interleukin 12 is expressed and actively released by Crohn's disease intestinal lamina propria mononuclear cells. Gastroenterology 1997;112:1169-78.
10. Parronchi P, Romagnani P, Annunziato F, et al. Type 1 T-helper cell predominance and interleukin-12 expression in the gut of patients with Crohn's disease. Am J Pathol 1997;150:823-32.
11. Morris GP, Beck PL, Herridge MS, et al. Hapten-induced model of chronic inflammation and ulceration in the rat colon. Gastroenterology 1989;96:795-803.
12. Sadlack B, Merz H, Schorle M, et al. Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene. Cell 1993;75:253-61.
13. Powrie F, Leach MW, Mauze S, et al. Inhibition of Th1 responses prevents inflammatory bowel disease in scid mice reconstituted with CD45RBhi CD4+ T cells. Immunity 1994;1:553-62.
14. Boirivant M, Fuss IJ, Chu A, et al. Oxazalone colitis: a murine model of T helper cell type 2 colitis treatable with antibodies to interleukin 4. J Exp Med 1998;188:129-39.
15. H2 colitis model resembling ulcerative colitis, is mediated by IL-13-producing NK-T cells. Immunity 2002;17:629-38.
16. Dieleman LA, Ridwan BU, Tennyson GS, et al. Dextran sulfate sodium-induced colitis occurs in severe combined immunodeficient mice. Gastroenterology 1994;107:1643-52.
17. Dieleman LA, Palmen MJ, Akol H, et al. Chronic experimental colitis induced by dextran sulphate sodium (DSS) is characterized by Th1 and Th2 cytokines. Clin Exp Immunol 1998;114:385-91.
18. Kabashima K, Saji T, Murata T, et al. The prostaglandin receptor EP4 suppresses colitis, mucosal damage and CD4 cell activation in the gut. J Clin Invest 2002;109:883-93.
19. Grabstein KH, Eisenman J, Shanebeck K, et al. Cloning of a T cell growth factor that interacts with the beta chain of the interleukin-2 receptor. Science 1994;264:965-8.
20. Giri JG, Ahdieh M, Eisenman J, et al. Utilization of the beta and gamma chains of the IL-2 receptor by the novel cytokine IL-15. EMBO J 1994;13:2822-30.
21. Togaya Y, Bamford RN, DeFilippis AP, et al. IL-15: a pleiotropic cytokine with diverse receptor/signaling pathways whose expression is controlled at multiple levels. Immunity 1996;4:329-36.
22. Bamford RN, Grant AJ, Burton JD, et al. The interleukin (IL) 2 receptor beta chain is shared by IL-2 and a cytokine, provisionally designated IL-T, that stimulates T-cell proliferation and the induction of lymphokine-activated killer cells. Proc Natl Acad Sci U S A 1994;91 :4940-4.
23. Reinecker HC, MacDermott RP, Mirau S, et al. Intestinal epithelial cells both express and respond to interleukin 15. Gastroenterology 1996;111:1706-13.
24. Carson WE, Giri JG, Lindemann MJ, et al. Interleukin (IL) 15 is a novel cytokine that activates human natural killer cells via components of the IL-2 receptor. J Exp Med 1994;180:1395-403.
25. Armitage RJ, Macduff BM, Eisenman J, et al. IL-15 has stimulatory activity for the induction of B cell proliferation and differentiation. J Immunol 1995;154:483-90.
26. Hiromatsu K, Yoshikai Y, Matsuzaki G, et al. A protective role of gamma/delta T cells in primary infection with Listeria monocytogenes in mice. J Exp Med 1992;175:49-56.
27. Nishimura H, Hiromatsu K, Kobayashi N, et al. IL-15 is a novel growth factor for murine gamma delta T cells induced by Salmonella infection. J Immunol 1996;156:663-9.
28. Kirman I, Nielsen OH. Increased numbers of interleukin-15-expressing cells in active ulcerative colitis. Am J Gastroenterol 1996;91:1789-94.
29. Sakai T, Kusugami K, Nishimura H, et al. Interleukin 15 activity in the rectal mucosa of inflammatory bowel disease. Gastroenterology 1998;114:1237-43.
30. Ohta N, Hiroi T, Kweon MN, et al. IL-15-dependent activation-induced cell death-resistant Th1 type CD8 alpha beta+NK1.1 + T cells for the development of small intestinal inflammation. J Immunol 2002;169:460-8.
31. Cooper HS, Murthy SNS, Shah RS, et al. Clinicopathologic study of dextran sulfate sodium experimental murine colitis. Lab Invest 1993;69:238-49.
32. Obermeier F, Dunger N, Deml L, et al. CpG motifs of bacterial DNA exacerbate colitis of dextran sulfate sodium-treated mice. Eur J Immunol 2002;32:2084-92.
33. Arstila T, Arstila TP, Calbo S, et al. Identical T cell clones are located within the mouse gut epithelium and lamina propria and circulate in the thoracic duct lymph. J Exp Med 2000;191:823-34.
34. Bouma G, Strober W. The immunological and genetic basis of inflammatory bowel disease. Nat Rev Immunol 2003;3:521-33.
35. Kitajima S, Takuma S, Morimoto M. Changes in colonic mucosal permeability in mouse colitis induced with dextran sulfate sodium. Exp Anim 1999;48:137-43.
36. Egger B, Bajaj-Elliott M, MacDonald TT, et al. Characterisation of acute murine dextran sodium sulphate colitis: cytokine profile and dose dependency. Digestion 2000;62:240-8.
37. Dohi T, Fujihashi K, Kiyono H, et al. Mice deficient in Th1- and Th2-type cytokines develop distinct forms of hapten-induced colitis. Gastroenterology 2000;119:724-33.
38. Takagi H, Kanai T, Okazawa A, et al. Contrasting action of IL-12 and IL-18 in the development of dextran sodium sulphate colitis in mice. Scand J Gastroenterol 2003;38:837-44.
39. Iwashita E, Miyahara T, Hino K, et al. High nitric oxide synthase activity in endothelial cells in ulcerative colitis. J Gastroenterol 1995;30:551-4.
40. Rachmilewitz D, Stamler JS, Bachwich D, et al. Enhanced colonic nitric oxide generation and nitric oxide synthase activity in ulcerative colitis and Crohn's disease. Gut 1995;36:718-23.
41. McKenzie SJ, Baker MS, Buffinton GD, et al. Evidence of oxidant-induced injury to epithelial cells during inflammatory bowel disease. J Clin Invest 1996;98:136-41.
42. Rachmilewitz D, Karmeli F, Okon E, et al. Experimental colitis is ameliorated by inhibition of nitric oxide synthase activity. Gut 1995;37:247-55.
43. Obermeier F, Kojouharoff G, Hans W, et al. Interferon-gamma (IFN-gamma)- and tumour necrosis factor (TNF)-induced nitric oxide as toxic effector molecule in chronic dextran sulphate sodium (DSS)-induced colitis in mice. Clin Exp Immunol 1999;116:238-45.
44. Kolios G, Brown Z, Robson RL, et al. Inducible nitric oxide synthase activity and expression in a human colonic epithelial cell line, HT-29. Br J Pharmacol 1995;116:2866-72.
45. Fehniger TA, Caligiuri MA. Interleukin 15: biology and relevance to human disease. Blood 2001;97:14-32.
46. Mastroianni CM, d'Ettorre G, Forcina G, et al. Teaching tired T cells to fight HIV: time to test IL-15 for immunotherapy? Trends Immunol 2004;25:121-5.
47. Tsunobuchi H, Nishimura H, Goshima F. Memory-type CD8+ T cells protect IL-2 receptor alpha-deficient mice from systemic infection with herpes simplex virus type 2. J Immunol 2000;165:4552-60.
48. Ohteki T, Suzue K, Maki C, et al. Critical role of IL-15-11-15R for antigen-presenting cell functions in the innate immune response. Nat Immunol 2001;2:1138-43.
49. Naito Y, Takagi T, Uchiyama K, et al. Reduced intestinal inflammation induced by dextran sodium sulfate in interleukin-6-deficient mice. Int J Mol Med 2004;14:191-6.
50. Siegmund B, Lehr HA, Fantuzzi G, et al. IL-1 beta-converting enzyme (caspase-1) in intestinal inflammation. Proc Natl Acad Sci U S A 2001;98:13249-54.
51. Kojouharoff G, Hans W, Obermeier F, et al. Neutralization of tumor necrosis factor (TNF) but not of IL-1 reduces inflammation in chronic dextran sulphate sodium-induced colitis in mice. Clin Exp Immunol 1997;107:353-8.
52. Naito Y, Takagi T, Handa O, et al. Enhanced intestinal inflammation induced by dextran sulfate sodium in tumor necrosis factor-alpha deficient mice. J Gastroenterol Hepatol 2003;18:560-9.