Fluoxetine and cocaine induce the epigenetic factors MeCP2 and MBD1 in adult rat brain

Molecular Pharmacology

Volumn 70, Issue 2, 2006, Pages 487-492

  Cassel, Suzanne ^a   Carouge, Delphine ^b   Gensburger, Claire ^b   Anglard, Patrick ^b   Burgun, Claude ^b   Dietrich, Jean Bernard ^b   Aunis, Dominique ^b   Zwiller, Jean ^b,c  

^a CNRS   (France)

^b INSERM   (France)

^c CENTRE DE NEUROCHIMIE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID RECEPTOR; BINDING PROTEIN; COCAINE; FLUOXETINE; HISTONE DEACETYLASE 2; HISTONE H3; MESSENGER RNA; METHYL CPG BINDING PROTEIN 2; PROTEIN MBD 1; SEROTONIN; UNCLASSIFIED DRUG; VANOXERINE;

ACETYLATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CAUDATE NUCLEUS; CONTROLLED STUDY; DENTATE GYRUS; EPIGENETICS; FRONTAL CORTEX; GENE EXPRESSION; GENE SILENCING; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; MALE; MITOSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PUTAMEN; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA SYNTHESIS; SIGNAL TRANSDUCTION;

ANIMALS; BRAIN; BRAIN-DERIVED NEUROTROPHIC FACTOR; COCAINE; DNA-BINDING PROTEINS; EPIGENESIS, GENETIC; FLUOXETINE; GAMMA-AMINOBUTYRIC ACID; IMMUNOHISTOCHEMISTRY; MALE; METHYL-CPG-BINDING PROTEIN 2; RATS; RATS, WISTAR; RNA, MESSENGER; SEROTONIN;

EID: 33746256453     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.106.022301     Document Type: Article

References (30)

1. Akbarian S, Chen RZ, Gribnau J, Rasmussen TP, Fong H, Jaenisch R, and Jones EG (2001) Expression pattern of the Rett syndrome gene MeCP2 in primate prefrontal cortex. Neurobiol Dis 8:784-791.
2. Amir RE, Van den Veyver IB, Wan M, Tran CQ, Francke U, and Zoghbi HY (1999) Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2. Nat Genet 23:185-188.
3. Buckmaster PS, Yamawaki R, and Zhang GF (2002) Axon arbors and synaptic connections of a vulnerable population of interneurons in the dentate gyrus in vivo. J Comp Neurol 445:360-373.
4. Cassel S, Revel MO, Kelche C, and Zwiller J (2004) Expression of the methyl-CpG-binding protein MeCP2 in rat brain. An ontogenetic study. Neurobiol Dis 15:206-211.
5. Celio MR (1990) Calbindin D-28k and parvalbumin in the rat nervous system. Neuroscience 35:375-475.
6. Chen WG, Chang Q, Lin Y, Meissner A, West AE, Griffith EC, Jaenisch R, and Greenberg ME (2003) Derepression of BDNF transcription involves calciumdependent phosphorylation of MeCP2. Science (Wash DC) 302:885-889.
7. Cheung P, Allis CD, and Sassone-Corsi P (2000) Signaling to chromatin through histone modifications. Cell 103:263-271.
8. Fan G and Hutnick L (2005) Methyl-CpG binding proteins in the nervous system. Cell Res 15:255-261.
9. Hagberg B and Witt-Engerstrom I (1987) Rett syndrome: epidemiology and nosologyprogress in knowledge 1986. Brain Dev 9:451-457.
10. Halasy K, Miettinen R, Szabat E, and Freund TF (1992) GABAergic interneurons are the major postsynaptic targets of median raphe afferents in the rat dentate gyrus. Eur J Neurosci 4:144-153.
11. Hendrich B and Bird A (1998) Identification and characterization of a family of mammalian methyl-CpG binding proteins. Mol Cell Biol 18:6538-6547.
12. Horike S, Cai S, Miyano M, Cheng JF, and Kohwi-Shigematsu T (2005) Loss of silent-chromatin looping and impaired imprinting of DLX5 in Rett syndrome. Nat Genet 37:31-40.
13. Jones PL, Veenstra GJ, Wade PA, Vermaak D, Kass SU, Landsberger N, Strouboulis J, and Wolffe AP (1998) Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription. Nat Genet 19:187-191.
14. Kita H and Kitai ST (1988) Glutamate decarboxylase immunoreactive neurons in rat neostriatum: their morphological types and populations. Brain Res 447:346-352.
15. Kriaucionis S and Bird A (2003) DNA methylation and Rett syndrome. Hum Mol Genet 12:R221-R227.
16. Kriaucionis S and Bird A (2004) The major form of MeCP2 has a novel N-terminus generated by alternative splicing. Nucleic Acids Res 32:1818-1823.
17. Kumar A, Choi KH, Renthal W, Tsankova NM, Theobald DE, Truong HT, Russo SJ, Laplant Q, Sasaki TS, Whistler KN, et al. (2005) Chromatin remodeling is a key mechanism underlying cocaine-induced plasticity in striatum. Neuron 48:303-314.
18. Levine AA, Guan Z, Barco A, Xu S, Kandel ER, and Schwartz JH (2005) CREB-binding protein controls response to cocaine by acetylating histones at the fosB promoter in the mouse striatum. Proc Natl Acad Sci USA 102:19186-19191.
19. Mnatzakanian GN, Lohi H, Munteanu I, Alfred SE, Yamada T, MacLeod PJ, Jones JR, Scherer SW, Schanen NC, Friez MJ, et al. (2004) previously unidentified MECP2 open reading frame defines a new protein isoform relevant to Rett syndrome. Nat Genet 36:339-341.
20. Naidu S (1997) Rett syndrome: a disorder affecting early brain growth. Ann Neurol 42:3-10.
21. Nan X, Campoy FJ, and Bird A (1997) MeCP2 is a transcriptional repressor with abundant binding sites in genomic chromatin. Cell 88:471-481.
22. Nan X, Ng HH, Johnson CA, Laherty CD, Turner BM, Eisenman RN, and Bird A (1998) Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex. Nature (Lond) 393:386-389.
23. 3H]5-hydroxytryptamine. Neuroscience 6:115-138.
24. Ritz MC, Cone EJ, and Kuhar MJ (1990) Cocaine inhibition of ligand binding at dopamine, norepinephrine and serotonin transporters: a structure-activity study. Life Sci 46:635-645.
25. Rossi A, Barraco A, and Donda P (2004) Fluoxetine: a review on evidence based medicine. Ann Gen Hosp Psychiatry 3:2.
26. Samaco RC, Hogart A, and Lasalle JM (2005) Epigenetic overlap in autism-spectrum neurodevelopmental disorders: MECP2 deficiency causes reduced expression of UBE3A and GABRB3. Hum Mol Genet 14:483-492.
27. Shahbazian M, Young J, Yuva-Paylor L, Spencer C, Antalffy B, Noebels J, Armstrong D, Paylor R, and Zoghbi H (2002) Mice with truncated MeCP2 recapitulate many Rett syndrome features and display hyperacetylation of histone H3. Neuron 35:243-254.
28. Shahbazian MD and Zoghbi HY (2002) Rett syndrome and MeCP2: linking epigenetics and neuronal function. Am J Hum Genet 71:1259-1272.
29. Wade PA (2001) Methyl CpG binding proteins: coupling chromatin architecture to gene regulation. Oncogene 20:3166-3173.
30. Zhao X, Ueba T, Christie BR, Barkho B, McConnell MJ, Nakashima K, Lein ES, Eadie BD, Willhoite AR, Muotri AR, et al. (2003) Mice lacking methyl-CpG binding protein 1 have deficits in adult neurogenesis and hippocampal function. Proc Natl Acad Sci USA 100:6777-6782.