CNS glia are targets for GDNF and neurturin

Histochemistry and Cell Biology

Volumn 110, Issue 6, 1998, Pages 595-601

  Franke, Barbara ^a   Figiel, Maciej ^a   Engele, Jürgen ^a  

^a UNIVERSITY OF ULM   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; NERVE GROWTH FACTOR; NEURTURIN; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN DEVELOPMENT; CONTROLLED STUDY; CORPUS STRIATUM; DIENCEPHALON; EMBRYO; GESTATIONAL AGE; GLIA; IMMUNOCYTOCHEMISTRY; MESENCEPHALON; NEWBORN; NONHUMAN; PONS; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ACTINS; ANIMALS; ANIMALS, NEWBORN; BRAIN; CELL LINE; DNA PRIMERS; DROSOPHILA PROTEINS; FEMALE; GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR; GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR RECEPTORS; NERVE GROWTH FACTORS; NERVE TISSUE PROTEINS; NEUROGLIA; NEURTURIN; PREGNANCY; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-RET; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR PROTEIN-TYROSINE KINASES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION;

EID: 0031760589     PISSN: 09486143     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004180050322     Document Type: Article

References (30)

1. Arenas E, Trupp M, Åkerud P, Ibáńez CF (1995) GDNF prevents degeneration and promotes the phenotype of brain adrenergic neurons in vivo. Neuron 15:1465-1473
2. Baloh RH, Tansey MG, Golden JP, Creedon DJ, Heuckroth RO, Keck CL, Zimonjic DB, Popescu NC, Johnson Jr EM, Milbrandt J (1997) TrnR2, a novel receptor that mediates neurturin and GDNF signaling through Ret. Neuron 18:793-802
3. Buj-Bello A, Adu J, Pinon LGP, Horton A, Thompson J, Rosenthal A, Chinehetru M, Buchman VL, Davies AM (1997) Neurturin responsiveness requires a GPI-linked receptor, and the Ret receptor tyrosine kinase. Nature 387:721-724
4. Choi-Lundberg DL, Bohn MC (1995) Ontogeny and distribution of glial cell line-derived neurotrophic factor (GDNF) mRNA in rat. Dev Brain Res 85:80-88
5. Chomczynski P, Sacchi N (1987) Single-step method of RNA isolation by acidic guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156-159
6. DeYoung BR, Swanson PE, Argenyi ZB, Ritter JH, Fitzgibbon JF, Stahl DJ, Hoover W, Wick MR (1995) CD31 immmunoreactivity in mesenchymal neoplasms of the skin and subcutis: report of 145 cases and review of putative immunohistologic markers of endothelial differentiation. J Cutan Pathol 22:215-222
7. Engele J, Bohn MC (1992) Effects of acidic and basic fibroblast growth factors (aFGF, bFGF) on glial precursor cell proliferation: age-dependency and region-specificity. Dev Biol 152:363-372
8. Engele J, Schilling K (1996) Growth factor-induced c-fos expression defines distinct subsets of midbrain dopaminergic neurons. Neuroscience 73:397-406
9. Engele J, Rieck H, Choi-Lundberg D, Bohn MC (1996) Evidence for a novel neurotrophic factor for dopaminergic neurons secreted from mesencephalic glial cell lines. J Neurosci Res 43:576-586
10. Giehl KM, Schacht CM, Yan Q, Mestres P (1997) GDNF is a trophic factor for adult rat corticospinal neurons and promotes their long-term survival after axotomy in vivo. Eur J Neurosci 9:2479-2488
11. Glazner GW, Mu X, Springer JE (1998) Localization of glial cell line-derived neurotrophic factor receptor alpha and c-ret mRNA in rat central nervous system. J Comp Neurol 391:42-49
12. Horger B, Nishimura M, Armanini M, Wang LC, Poulsen K, Rosenblad C, Kirik D, Moffat B, Simmons L, Johnson E, Milbrandt J, Rosenthal A, Bjorklund A, Vandlen R, Hynes M, Phillips H (1998) Neurturin exerts potent actions on survival and function of midbrain dopmainergic neurons. Mol Cell Neurosci (in press)
13. Jing S, Wen D, Yu Y, Holst PL, Luo Y, Fang M, Tamir R, Antonio L, Hu Z, Cupples R, Louis JL, Hu S, Altrock BW, Fox GM (1996) GDNF-induced activation of the Ret protein tyrosine kinase is mediated by GDNFRα, a novel receptor for GDNF. Cell 85:1113-1124
14. Jing S, Yu Y, Fang M, Hu Z, Holst PL, Boone T, Delaney J, Schultz H, Zhou R, Fox GM (1997) GFRα-2 and GFRα-3 are two new receptors for ligands of the GDNF family. J Biol-Chem 272:33111-33117
15. Klein RD, Sherman D, Ho W-H, Stone D, Bennett GL, Moffat B, Vandlen R, Simmons L, Gu Q, Hongo J-A, Devaux B, Poulson K, Armanini M, Nozaki C, Asai N, Goddard A, Phillips H, Henderson CE, Takahashi M, Rosenthal A (1997) A GPI-linked protein that interacts with Ret to form a candidate neurturin reeeptor. Nature 387:717-721
16. Kotzbauer PT, Lampe PA, Heuckeroth RO, Golden JP, Creedon DJ, Johnson EM Jr, Milbrandt J (1996) Neurturin, a relative of glial cell line-derived neurotrophic factor. Nature 384:467-470
17. Lin L-FH, Doherty DH, Lile JD, Bektesh S, Collins F (1993) GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons. Science 260:1131-1132
18. McMahon HT, Sudhof TC (1995) Synaptic core complex of synaptobrevin, syntaxin, and SNAP25 forms high affinity alpha-SNAP binding sites. J Biol Chem 270:2213-2217
19. Milbrandt J, Sauvage FJ de, Fahrner TJ, Baloh RH, Leitner ML, Tansey MG, Lampe PA, Heuckeroth RO, Kotzbauer PT, Simburger KS, Golden JP, Davies JA, Vejsada R, Kazo AC, Hynes M, Sherman D, Nishimura M, Wang L-C, Vandlen R, Moffat B, Klein RD, Poulson K, Gray C, Garces A, Henderson CE, Phillips HS, Johnson EM Jr (1998) Persephin, a novel neurotrophic factor related to GDNF and neurturin. Neuron 20: 245-253
20. Mount HTJ, Dean DO, Alberch J, Dreyfus CF, Black IB (1995) Glial cell line-derived neurotrophic factor promotes the survival and morphologic differentiation of Purkinje cells. Proc Natl Acad Sci USA 92:9092-9096
21. Nosrat CA, Tomac A, Hoffer BJ, Olson L (1997) Cellular and developmental patterns of Ret and glial cell line-derived neurotrophic factor alpha mRNAs. Exp Brain Res 115:410-422
22. Oppenheim RW, Houenou LJ, Johnson JE, Lin L-FH, Li L, Lo AC, Newsome AL, Prevette DM, Wang S (1995) Developing motor neurons rescued from programmed and axotomy-induced cell death by GDNF. Nature 373:344-346
23. Pochon MM, Menoud A, Tseng JL, Zurn AD, Aebischer P (1997) Neuronal GDNF expression in the adult rat nervous system identified by in situ hybridization. Eur J Neurosci 9:463-471
24. Raff MC, Miller RH, Noble M (1983) A glial progenitor cell that develops into an astrocyte or an oligodendrocyte depending on culture medium. Nature 303:390-396
25. Schubert D, Heinemann S, Carlisle W, Tarikas H, Kimes B, Patrick J, Steinbach JH, Culp W, Brandt BL (1974) Clonal cell lines from the rat nervous system. Nature 249:224-227
26. Springer JE, Mu X, Bergmann LW, Trojanowski JQ (1994) Expression of GDNF mRNA in rat and human nervous tissue. Exp Neurol 127:167-170
27. Treanor JJ, Goodman L, Sauvage F de, Stone DM, Poulsen KT, Beck CD, Gray C, Armanini MP, Pollock RA, Hefti F, Phillips HS, Goddard A, Moore MW, Buj-Bello A, Davies AM, Asai N, Takahashi M, Vandlen R, Henderson CE, Rosenthal A (1996) Characterization of a multicomponent receptor for GDNF. Nature 382:80-83
28. Widenfalk J, Nosrat C, Tomac A, Westphal H, Hoffer B, Olson L (1997) Neurturin and glial cell line-derived neurotrophic factor receptor-β (GDNFR-β), novel proteins related to GDNF and GDNFR-α with specific cellular patterns of expression suggesting roles in the developing and adult nervous system and in peripheral organs. J Neurosci 17:8506-8519
29. Yan Q, Matheson C, Lopez OT (1995) In vivo neurotrophic effects of GDNF on neonatal and adult facial motor neurons. Nature 373:341-344
30. Yu T, Scully S, Yu Y, Fox GM, Jing S, Zhou R (1998) Expression of GDNF family receptor components during development: implications in the mechanisms of interaction. J Neurosci 15:4684-4696