Endothelin-1 reverses the histone deacetylase inhibitor-induced increase in glial glutamate transporter transcription without affecting histone acetylation levels

Neurochemistry International

Volumn 55, Issue 1-3, 2009, Pages 22-27

  Allritz, Claudia ^a   Bette, Stefanie ^a   Figiel, Maciej ^b   Engele, Jürgen ^a  

^a UNIVERSITY OF LEIPZIG   (Germany)

^b ADAM MICKIEWICZ UNIVERSITY   (Poland)

Author keywords

Astrocytes; GLAST; GLT 1; MCT 1; Trichostatin A

Indexed keywords

ENDOTHELIN 1; EXCITATORY AMINO ACID TRANSPORTER; EXCITATORY AMINO ACID TRANSPORTER 1; EXCITATORY AMINO ACID TRANSPORTER 2; HISTONE H3; HISTONE H4; TRICHOSTATIN A; VESICULAR GLUTAMATE TRANSPORTER 1;

ACETYLATION; ANIMAL CELL; ARTICLE; ASTROCYTE; CONTROLLED STUDY; GENE EXPRESSION; GENETIC TRANSCRIPTION; GLIA; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RAT;

ACETYLATION; AMINO ACID TRANSPORT SYSTEM X-AG; ANIMALS; ASTROCYTES; BLOTTING, WESTERN; CELLS, CULTURED; ENDOTHELIN-1; ENZYME INHIBITORS; EXCITATORY AMINO ACID TRANSPORTER 1; EXCITATORY AMINO ACID TRANSPORTER 2; HISTONE DEACETYLASES; HISTONES; HYDROXAMIC ACIDS; MONOCARBOXYLIC ACID TRANSPORTERS; NEUROGLIA; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA; SYMPORTERS;

EID: 64949100991     PISSN: 01970186     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuint.2008.12.020     Document Type: Article

References (44)

1. Aguirre G., Rosas S., López-Bayghen E., and Ortega A. Valproate-dependent transcriptional regulation of GLAST/EAAT1 expression: involvement of Ying-Yang 1. Neurochem. Int. 52 (2008) 1322-1331
2. Arzberger T., Krampfl K., Leimgruber S., and Weindl A. Changes of NMDA receptor subunit (NR1, NR2B) and glutamate transporter (GLT1) mRNA expression in Huntington's disease-an in situ hybridization study. J. Neuropathol. Exp. Neurol. 56 (1997) 440-454
3. Bernstein B.E., Kamal M., Lindblad-Toh K., Bekiranov S., Bailey D.K., Huebert D.J., McMahon S., Karlsson E.K., Kulbokas III E.J., Gingeras T.R., Schreiber S.L., and Lander E.S. Genomic maps and comparative analysis of histone modifications in human and mouse. Cell 120 (2005) 169-181
4. Butler R., and Bates G.P. Histone deacetylase inhibitors as therapeutics for polyglutamine disorders. Nat. Rev. Neurosci. 7 (2006) 784-796
5. Custer S.K., Garden G.A., Gill N., Rueb U., Libby R.T., Schultz C., Guyenet S.J., Deller T., Westrum L.E., Sopher B.L., and La Spada A.R. Bergmann glia expression of polyglutamine-expanded ataxin-7 produces neurodegeneration by impairing glutamate transport. Nat. Neurosci. 9 (2006) 1302-1311
6. Davenport A.P., and Maguire J.J. Endothelin. Handb. Exp. Pharmacol. 176 (2006) 295-329
7. Doetzlhofer A., Rotheneder H., Lagger G., Koranda M., Kurtev V., Brosch G., Wintersberger E., and Seiser C. Histone deacetylase 1 can repress transcription by binding to Sp1. Mol. Cell. Biol. 19 (1999) 5504-5511
8. Figiel M., Allritz C., Lehmann C., and Engele J. Gap junctional control of glial glutamate transporter expression. Mol. Cell Neurosci. 35 (2007) 130-137
9. Figiel M., Maucher T., Rozyczka J., Bayatti N., and Engele J. Regulation of glial glutamate transporter expression by growth factors. Exp. Neurol. 183 (2003) 124-135
10. Glozak M.A., and Seto E. Histone deacetylases and cancer. Oncogene 26 (2007) 5420-5432
11. Hernandez M., Shao Q., Yang X.J., Luh S.P., Kandouz M., Batist G., Laird D.W., and Alaoui-Jamali M.A. A histone deacetylation-dependent mechanism for transcriptional repression of the gap junction gene cx43 in prostate cancer cells. Prostate 66 (2006) 1151-1161
12. Ishikawa N., Takemura M., Koyama Y., Shigenaga Y., Okada T., and Baba A. Endothelins promote the activation of astrocytes in rat neostriatum through ET(B) receptors. Eur. J. Neurosci. 9 (1997) 895-901
13. Knowles J., Loizidou M., and Taylor I. Endothelin-1 and angiogenesis in cancer. Curr. Vasc. Pharmacol. 3 (2005) 309-314
14. Koyama Y., Takemura M., Fujiki K., Ishikawa N., Shigenaga Y., and Baba A. BQ788, an endothelin ET(B) receptor antagonist, attenuates stab wound injury-induced reactive astrocytes in rat brain. Glia 26 (1999) 268-271
15. Koyama Y., Yoshioka Y., Matsuda T., and Baba A. Focal adhesion kinase is required for endothelin-induced cell cycle progression of cultured astrocytes. Glia 43 (2003) 185-189
16. Kurdistani S.K., Tavazoie S., and Grunstein M. Mapping global histone acetylation patterns to gene expression. Cell 117 (2004) 721-733
17. Kuwahara K., Saito Y., Ogawa E., Takahashi N., Nakagawa Y., Naruse Y., Harada M., Hamanaka I., Izumi T., Miyamoto Y., Kishimoto I., Kawakami R., Nakanishi M., Mori N., and Nakao K. The neuron-restrictive silencer element-neuron-restrictive silencer factor system regulates basal and endothelin 1-inducible atrial natriuretic peptide gene expression in ventricular myocytes. Mol. Cell. Biol. 21 (2001) 2085-2097
18. Lazarini F., Strosberg A.D., Couraud P.O., and Cazaubon S.M. Coupling of ETB endothelin receptor to mitogen-activated protein kinase stimulation and DNA synthesis in primary cultures of rat astrocytes. J. Neurochem. 66 (1996) 459-465
19. Lee H.J., Chun M., and Kandror K.V. Tip60 and HDAC7 interact with the endothelin receptor a and may be involved in downstream signaling. J. Biol. Chem. 276 (2001) 16597-16600
20. Lehmann C., Eisner F., and Engele J. Role of endothelins as mediators of injury-induced alterations of glial glutamate turnover. J. Neurosci. Res. 86 (2008) 660-667
21. Leonova J., Thorlin T., Aberg N.D., Eriksson P.S., Ronnback L., and Hansson E. Endothelin-1 decreases glutamate uptake in primary cultured rat astrocytes. Am. J. Physiol. Cell Physiol. 281 (2001) C1495-C1503
22. Mai A., Massa S., Rotili D., Cerbara I., Valente S., Pezzi R., Simeoni S., and Ragno R. Histone deacetylation in epigenetics: an attractive target for anticancer therapy. Med. Res. Rev. 25 (2005) 261-309
23. Matsuura S., Ikegaya Y., Yamada M.K., Nishiyama N., and Matsuki N. Endothelin downregulates the glutamate transporter GLAST in cAMP-differentiated astrocytes in vitro. Glia 37 (2002) 178-182
24. McMahon S.J., Pray-Grant M.G., Schieltz D., Yates III J.R., and Grant P.A. Polyglutamine-expanded spinocerebellar ataxia-7 protein disrupts normal SAGA and SLIK histone acetyltransferase activity. Proc. Natl. Acad. Sci. U.S.A. 102 (2005) 8478-8482
25. Nakagawa Y., Kuwahara K., Harada M., Takahashi N., Yasuno S., Adachi Y., Kawakami R., Nakanishi M., Tanimoto K., Usami S., Kinoshita H., Saito Y., and Nakao K. Class II HDACs mediate CaMK-dependent signaling to NRSF in ventricular myocytes. J. Mol. Cell. Cardiol. 41 (2006) 1010-1022
26. Nelson J., Bagnato A., Battistini B., and Nisen P. The endothelin axis: emerging role in cancer. Nat. Rev. Cancer 3 (2003) 110-116
27. Pierre K., and Pellerin L. Monocarboxylate transporters in the central nervous system: distribution, regulation and function. J. Neurochem. 94 (2005) 1-14
28. Pla P., and Larue L. Involvement of endothelin receptors in normal and pathological development of neural crest cells. Int. J. Dev. Biol. 47 (2003) 315-325
29. Rogers S.D., Peters C.M., Pomonis J.D., Hagiwara H., Ghilardi J.R., and Mantyh P.W. Endothelin B receptors are expressed by astrocytes and regulate astrocyte hypertrophy in the normal and injured CNS. Glia 41 (2003) 180-190
30. Rozyczka J., Figiel M., and Engele J. Endothelins negatively regulate glial glutamate transporter expression. Brain Pathol. 14 (2004) 406-414
31. Sadri-Vakili G., Bouzou B., Benn C.L., Kim M.O., Chawla P., Overland R.P., Glajch K.E., Xia E., Qiu Z., Hersch S.M., Clark T.W., Yohrling G.J., and Cha J.H. Histones associated with downregulated genes are hypo-acetylated in Huntington's disease models. Hum. Mol. Genet. 16 (2007) 1293-1306
32. Sadri-Vakili G., and Cha J.H. Mechanisms of disease: histone modifications in Huntington's disease. Nat. Clin. Pract. Neurol. 2 (2006) 330-338
33. Schinelli S. Pharmacology and physiopathology of the brain endothelin system: an overview. Curr. Med. Chem. 13 (2006) 627-638
34. Schmidt-Ott K.M., Xu A.D., Tuschick S., Liefeldt L., Kresse W., Verkhratsky A., Kettenmann H., and Paul M. Hypoxia reverses dibutyryl-cAMP-induced stellation of cultured astrocytes via activation of the endothelin system. FASEB J. 15 (2001) 1227-1229
35. Shah R. Endothelins in health and disease. Eur. J. Intern. Med. 18 (2007) 272-282
36. Sheldon A.L., and Robinson M.B. The role of glutamate transporters in neurodegenerative diseases and potential opportunities for intervention. Neurochem. Int. 51 (2007) 333-355
37. Shin J.Y., Fang Z.H., Yu Z.X., Wang C.E., Li S.H., and Li X.J. Expression of mutant huntingtin in glial cells contributes to neuronal excitotoxicity. J. Cell Biol. 171 (2005) 1001-1012
38. Stanimirovic D.B., Ball R., Mealing G., Morley P., and Durkin J.P. The role of intracellular calcium and protein kinase C in endothelin stimulated proliferation of rat type I astrocytes. Glia 15 (1995) 119-130
39. Ström A.L., Forsgren L., and Holmberg M. A role for both wild-type and expanded ataxin-7 in transcriptional regulation. Neurobiol. Dis. 20 (2005) 646-655
40. Su Z.Z., Leszczyniecka M., Kang D.C., Sarkar D., Chao W., Volsky D.J., and Fisher P.B. Insights into glutamate transport regulation in human astrocytes: cloning of the promoter for excitatory amino acid transporter 2 (EAAT2). Proc. Natl. Acad. Sci. U.S.A. 100 (2003) 1955-1960
41. Uesugi M., Kasuya Y., Hama H., Yamamoto M., Hayashi K., Masaki T., and Goto K. Endogenous endothelin-1 initiates astrocytic growth after spinal cord injury. Brain Res. 728 (1996) 255-259
42. Vinken M., Henkens T., Vanhaecke T., Papeleu P., Geerts A., Van Rossen E., Chipman J.K., Meda P., and Rogiers V. Trichostatin a enhances gap junctional intercellular communication in primary cultures of adult rat hepatocytes. Toxicol. Sci. 91 (2006) 484-492
43. Wu J.Y., Niu F.N., Huang R., and Xu Y. Enhancement of glutamate uptake in 1-methyl-4-phenylpyridinium-treated astrocytes by trichostatin A. Neuroreport 19 (2008) 1209-1212
44. Zschocke J., Allritz C., Engele J., and Rein T. DNA methylation dependent silencing of the human glutamate transporter EAAT2 gene in glial cells. Glia 55 (2007) 663-674