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Volumn 4, Issue 1, 2009, Pages 42-48

Adiponectin, and the adiponectin paradox in human metabolism;Adiponektyna i paradoks adiponektyny w metabolizmie człowieka

Author keywords

Adipocytokines; Adiponectin; Metabolism

Indexed keywords

ADIPONECTIN; ADIPONECTIN RECEPTOR 1; ADIPONECTIN RECEPTOR 2; INSULIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA;

EID: 75749087242     PISSN: 18969666     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (2)

References (79)
  • 1
    • 0028787490 scopus 로고
    • A novel serum protein similar to C1q, produced exclusively in adipocytes
    • Scherer PE, Williams S, Fogliano M, et al. A novel serum protein similar to C1q, produced exclusively in adipocytes. J Biol Chem 1995; 270: 26746-9.
    • (1995) J Biol Chem , vol.270 , pp. 26746-26749
    • Scherer, P.E.1    Williams, S.2    Fogliano, M.3
  • 2
    • 17544382289 scopus 로고    scopus 로고
    • AdipoQ is a novel adipose-specific gene dysregulated in obesity
    • Hu E, Liang P, Spiegelman BM. AdipoQ is a novel adipose-specific gene dysregulated in obesity. J Biol Chem 1996; 271: 10697-703.
    • (1996) J Biol Chem , vol.271 , pp. 10697-10703
    • Hu, E.1    Liang, P.2    Spiegelman, B.M.3
  • 3
    • 0029980285 scopus 로고    scopus 로고
    • cDNA cloning and expression of a novel adipose specific collagen-like factor, apM1 (Adipose Most abundant gene transcript 1)
    • Maeda K, Okubo K, Shimomura I, et al. cDNA cloning and expression of a novel adipose specific collagen-like factor, apM1 (Adipose Most abundant gene transcript 1). Biochem Biophys Res Commun 1996; 221: 286-9.
    • (1996) Biochem Biophys Res Commun , vol.221 , pp. 286-289
    • Maeda, K.1    Okubo, K.2    Shimomura, I.3
  • 4
    • 0029836585 scopus 로고    scopus 로고
    • Isolation and characterization of GBP28, a novel gelatin-binding protein purified from human plasma
    • Nakano Y, Tobe T, Choi-Miura N, et al. Isolation and characterization of GBP28, a novel gelatin-binding protein purified from human plasma. J Biochem 1996; 120: 803-12.
    • (1996) J Biochem , vol.120 , pp. 803-812
    • Nakano, Y.1    Tobe, T.2    Choi-Miura, N.3
  • 5
    • 0034881391 scopus 로고    scopus 로고
    • The adipocyte-secreted protein Acrp30 enhances hepatic insulin action
    • Berg AH, Combs TP, Du X, et al. The adipocyte-secreted protein Acrp30 enhances hepatic insulin action. Nature Med 2001; 7: 947-53.
    • (2001) Nature Med , vol.7 , pp. 947-953
    • Berg, A.H.1    Combs2    TP, D.X.3
  • 6
    • 0035852760 scopus 로고    scopus 로고
    • Proteolytic cleavage product of 30-kDa adipocyte complement-related protein increases fatty acid oxidation in muscle and causes weight loss in mice
    • Fruebis J, Tsao TS, Javorschi S, et al. Proteolytic cleavage product of 30-kDa adipocyte complement-related protein increases fatty acid oxidation in muscle and causes weight loss in mice. Proc Natl Acad Sci U S A 2001; 98: 2005-10.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 2005-2010
    • Fruebis, J.1    Tsao, T.S.2    Javorschi, S.3
  • 7
    • 0032510463 scopus 로고    scopus 로고
    • The crystal structure of a complement-1q family protein suggests an evolutionary link to tumor necrosis factor
    • Shapiro L, Scherer PE. The crystal structure of a complement-1q family protein suggests an evolutionary link to tumor necrosis factor. Curr Biol 1998; 8: 335-8.
    • (1998) Curr Biol , vol.8 , pp. 335-338
    • Shapiro, L.1    Scherer, P.E.2
  • 8
    • 0037066603 scopus 로고    scopus 로고
    • ACRP30, a new hormone controlling fat and glucose metabolism
    • Tsao T, Lodish H, Fruebis J. ACRP30, a new hormone controlling fat and glucose metabolism. Eur J Pharmacol 2002; 440: 213-21.
    • (2002) Eur J Pharmacol , vol.440 , pp. 213-221
    • Tsao, T.1    Lodish, H.2    Fruebis, J.3
  • 9
    • 0037984387 scopus 로고    scopus 로고
    • Structure-function studies of the adipocyte-secreted hormone Acrp30/adiponectin. Implications for metabolic regulation and bioactivity
    • Pajvani UB, Du X, Combs TP, et al. Structure-function studies of the adipocyte-secreted hormone Acrp30/adiponectin. Implications for metabolic regulation and bioactivity. J Biol Chem 2003; 278: 9073-85.
    • (2003) J Biol Chem , vol.278 , pp. 9073-9085
    • Pajvani1    UB, D.X.2    Combs, T.P.3
  • 10
    • 0037119375 scopus 로고    scopus 로고
    • Oligomerization state-dependent activation of NF-kappaB signaling pathway by adipocyte complement-related protein of 30 kDa (Acrp30)
    • Tsao T, Murrey H, Hug C, et al. Oligomerization state-dependent activation of NF-kappaB signaling pathway by adipocyte complement-related protein of 30 kDa (Acrp30). J Biol Chem 2002; 277: 29359-62.
    • (2002) J Biol Chem , vol.277 , pp. 29359-29362
    • Tsao, T.1    Murrey, H.2    Hug, C.3
  • 11
    • 0141924849 scopus 로고    scopus 로고
    • Impaired multimerization of human adiponectin mutants associated with diabetes: Molecular structure and multimer formation of adiponectin
    • Waki H, Yamauchi T, Kamon J, et al. Impaired multimerization of human adiponectin mutants associated with diabetes: Molecular structure and multimer formation of adiponectin. J Biol Chem 2003; 278: 40352-63.
    • (2003) J Biol Chem , vol.278 , pp. 40352-40363
    • Waki, H.1    Yamauchi, T.2    Kamon, J.3
  • 12
    • 19944431559 scopus 로고    scopus 로고
    • Generation of globular fragment of adiponectin by leukocyte elastase secreted by monocytic cell line THP-1
    • Waki H, Yamauchi T, Kamon J, et al. Generation of globular fragment of adiponectin by leukocyte elastase secreted by monocytic cell line THP-1. Endocrinology 2005; 146: 790-6.
    • (2005) Endocrinology , vol.146 , pp. 790-796
    • Waki, H.1    Yamauchi, T.2    Kamon, J.3
  • 13
    • 11144355637 scopus 로고    scopus 로고
    • Complex distribution, not absolute amount of adiponectin, correlates with thiazolidinedione-mediated improvement in insulin sensitivity
    • Pajvani UB, Hawkins M, Combs TP, et al. Complex distribution, not absolute amount of adiponectin, correlates with thiazolidinedione-mediated improvement in insulin sensitivity. J Biol Chem 2004; 279: 12152-62.
    • (2004) J Biol Chem , vol.279 , pp. 12152-12162
    • Pajvani, U.B.1    Hawkins, M.2    Combs, T.P.3
  • 14
    • 0036724336 scopus 로고    scopus 로고
    • Androgens decrease plasma adiponectin, an insulin-sensitizing adipocyte-derived protein
    • Nishizawa H, Shimomura I, Kishida K, et al. Androgens decrease plasma adiponectin, an insulin-sensitizing adipocyte-derived protein. Diabetes 2002; 51: 2734-41.
    • (2002) Diabetes , vol.51 , pp. 2734-2741
    • Nishizawa, H.1    Shimomura, I.2    Kishida, K.3
  • 15
    • 0037317488 scopus 로고    scopus 로고
    • Sexual differentiation, pregnancy, calorie restriction, and aging affect the adipocyte-specific secretory protein adiponectin
    • Combs TP, Berg AH, Rajala MW, et al. Sexual differentiation, pregnancy, calorie restriction, and aging affect the adipocyte-specific secretory protein adiponectin. Diabetes 2003; 52: 268-76.
    • (2003) Diabetes , vol.52 , pp. 268-276
    • Combs, T.P.1    Berg, A.H.2    Rajala, M.W.3
  • 16
    • 14344273991 scopus 로고    scopus 로고
    • Quantitative trait loci on chromosomes 3 and 17 influence phenotypes of the metabolic syndrome
    • Kissebah AH, Sonnenberg GE, Myklebust J, et al. Quantitative trait loci on chromosomes 3 and 17 influence phenotypes of the metabolic syndrome. Proc Natl Acad Sci U S A 2000; 97: 14478-83.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 14478-14483
    • Kissebah, A.H.1    Sonnenberg, G.E.2    Myklebust, J.3
  • 17
    • 0033652271 scopus 로고    scopus 로고
    • Genomewide search for type 2 diabetes-susceptibility genes in French whites: Evidence for a novel susceptibility locus for early-onset diabetes on chromosome 3q27-qter and independent replication of a type 2-diabetes locus on chromosome 1q21-q24
    • Vionnet N, Hani EH, Dupont S, et al. Genomewide search for type 2 diabetes-susceptibility genes in French whites: evidence for a novel susceptibility locus for early-onset diabetes on chromosome 3q27-qter and independent replication of a type 2-diabetes locus on chromosome 1q21-q24. Am J Hum Genet 2000; 67: 1470-80.
    • (2000) Am J Hum Genet , vol.67 , pp. 1470-1480
    • Vionnet, N.1    Hani, E.H.2    Dupont, S.3
  • 18
    • 0036230486 scopus 로고    scopus 로고
    • Genome-wide search for type 2 diabetes in Japanese affected sib-pairs confirms susceptibility genes on 3q, 15q, and 20q and identifies two new candidate loci on 7p and 11p
    • Mori Y, Otabe S, Dina C, et al. Genome-wide search for type 2 diabetes in Japanese affected sib-pairs confirms susceptibility genes on 3q, 15q, and 20q and identifies two new candidate loci on 7p and 11p. Diabetes 2002; 51: 1247-55.
    • (2002) Diabetes , vol.51 , pp. 1247-1255
    • Mori, Y.1    Otabe, S.2    Dina, C.3
  • 19
    • 19944429883 scopus 로고    scopus 로고
    • Common polymorphisms in the adiponectin gene ACDC are not associated with diabetes in Pima Indians
    • Vozarova de Courten B, Hanson RL, Funahashi T, et al. Common polymorphisms in the adiponectin gene ACDC are not associated with diabetes in Pima Indians. Diabetes 2005; 54: 284-9.
    • (2005) Diabetes , vol.54 , pp. 284-289
    • Vozarova de Courten, B.1    Hanson, R.L.2    Funahashi, T.3
  • 20
    • 0036061598 scopus 로고    scopus 로고
    • Genetic variation in the gene encoding adiponectin is associated with an increased risk of type 2 diabetes in the Japanese population
    • Hara K, Boutin P, Mori Y, et al. Genetic variation in the gene encoding adiponectin is associated with an increased risk of type 2 diabetes in the Japanese population. Diabetes 2002; 51: 536-40.
    • (2002) Diabetes , vol.51 , pp. 536-540
    • Hara, K.1    Boutin, P.2    Mori, Y.3
  • 21
    • 0036303146 scopus 로고    scopus 로고
    • Association of adiponectin mutation with type 2 diabetes: A candidate gene for the insulin resistance syndrome
    • Kondo H, Shimomura I, Matsukawa Y, et al. Association of adiponectin mutation with type 2 diabetes: a candidate gene for the insulin resistance syndrome. Diabetes 2002; 51: 2325-8.
    • (2002) Diabetes , vol.51 , pp. 2325-2328
    • Kondo, H.1    Shimomura, I.2    Matsukawa, Y.3
  • 22
    • 0036307162 scopus 로고    scopus 로고
    • A haplotype at the adiponectin locus is associated with obesity and other features of the insulin resistance syndrome
    • Menzaghi C, Ercolino T, Di Paola R, et al. A haplotype at the adiponectin locus is associated with obesity and other features of the insulin resistance syndrome. Diabetes 2002; 51: 2306-12.
    • (2002) Diabetes , vol.51 , pp. 2306-2312
    • Menzaghi, C.1    Ercolino, T.2    Di Paola, R.3
  • 23
    • 0036091918 scopus 로고    scopus 로고
    • Association of the T-G polymorphism in adiponectin (exon 2) with obesity and insulin sensitivity: Interaction with family history of type 2 diabetes
    • Stumvoll M, Tschritter O, Fritsche A, et al. Association of the T-G polymorphism in adiponectin (exon 2) with obesity and insulin sensitivity: interaction with family history of type 2 diabetes. Diabetes 2002; 51: 37-41.
    • (2002) Diabetes , vol.51 , pp. 37-41
    • Stumvoll, M.1    Tschritter, O.2    Fritsche, A.3
  • 24
    • 18644369745 scopus 로고    scopus 로고
    • Single-nucleotide polymorphism haplotypes in the both proximal promoter and exon 3 of the APM1 gene modulate adipocyte-secreted adiponectin hormone levels and contribute to the genetic risk for type 2 diabetes in French Caucasians
    • Vasseur F, Helbecque N, Dina C, et al. Single-nucleotide polymorphism haplotypes in the both proximal promoter and exon 3 of the APM1 gene modulate adipocyte-secreted adiponectin hormone levels and contribute to the genetic risk for type 2 diabetes in French Caucasians. Hum Mol Genet 2002; 11: 2607-14.
    • (2002) Hum Mol Genet , vol.11 , pp. 2607-2614
    • Vasseur, F.1    Helbecque, N.2    Dina, C.3
  • 25
    • 58149333293 scopus 로고    scopus 로고
    • Common variants in the adiponectin gene (ADIPOQ) associated with plasma adiponectin levels, type 2 diabetes, and diabetes-related quantitative traits. The Framingham Offspring Study
    • Hivert MF, Manning AK, McAteer JB, et al. Common variants in the adiponectin gene (ADIPOQ) associated with plasma adiponectin levels, type 2 diabetes, and diabetes-related quantitative traits. The Framingham Offspring Study. Diabetes 2008; 57: 3353-9.
    • (2008) Diabetes , vol.57 , pp. 3353-3359
    • Hivert, M.F.1    Manning, A.K.2    McAteer, J.B.3
  • 26
    • 0034577326 scopus 로고    scopus 로고
    • Decreased expression of apM1 in omental and subcutaneous adipose tissue of humans with type 2 diabetes
    • Statnick MA, Beavers LS, Conner LJ, et al. Decreased expression of apM1 in omental and subcutaneous adipose tissue of humans with type 2 diabetes. Int J Exp Diabetes Res 2000; 1: 81-8.
    • (2000) Int J Exp Diabetes Res , vol.1 , pp. 81-88
    • Statnick, M.A.1    Beavers, L.S.2    Conner, L.J.3
  • 27
    • 0041665074 scopus 로고    scopus 로고
    • Adiponectin mRNA levels in the abdominal adipose depots of nondiabetic women
    • Yang WS, Chen MH, Lee WJ, et al. Adiponectin mRNA levels in the abdominal adipose depots of nondiabetic women. Int J Obes Relat Metab Disord 2003; 27: 896-900.
    • (2003) Int J Obes Relat Metab Disord , vol.27 , pp. 896-900
    • Yang, W.S.1    Chen, M.H.2    Lee, W.J.3
  • 28
    • 0037306899 scopus 로고    scopus 로고
    • Adiponectin mRNA expression in subcutaneous adipose tissue is reduced in first-degree relatives of type 2 diabetic patients
    • Lihn AS, Østergard T, Nyholm B, et al. Adiponectin mRNA expression in subcutaneous adipose tissue is reduced in first-degree relatives of type 2 diabetic patients. Am J Physiol Endocrinol Metab 2002; 284: E443-8.
    • (2002) Am J Physiol Endocrinol Metab , vol.284
    • Lihn, A.S.1    Østergard, T.2    Nyholm, B.3
  • 29
    • 0037494960 scopus 로고    scopus 로고
    • Yamauchi T, Kamon J, Ito Y, et al. Cloning of adiponectin receptors that mediate antidiabetic metabolic effects. Nature 2003; 423: 762-9; erratum 2004; 431: 1123.
    • Yamauchi T, Kamon J, Ito Y, et al. Cloning of adiponectin receptors that mediate antidiabetic metabolic effects. Nature 2003; 423: 762-9; erratum 2004; 431: 1123.
  • 31
    • 3142701401 scopus 로고    scopus 로고
    • Insulin/Foxo1 pathway regulates expression levels of adiponectin receptors and adiponectin sensitivity
    • Tsuchida A, Yamauchi T, Ito Y, et al. Insulin/Foxo1 pathway regulates expression levels of adiponectin receptors and adiponectin sensitivity. J Biol Chem 2004; 279: 30817-22.
    • (2004) J Biol Chem , vol.279 , pp. 30817-30822
    • Tsuchida, A.1    Yamauchi, T.2    Ito, Y.3
  • 32
    • 2942594755 scopus 로고    scopus 로고
    • Adiponectin receptors gene expression and insulin sensitivity in non-diabetic Mexican Americans with or without a family history of type 2 diabetes
    • Civitarese AE, Jenkinson CP, Richardson D, et al. Adiponectin receptors gene expression and insulin sensitivity in non-diabetic Mexican Americans with or without a family history of type 2 diabetes. Diabetologia 2004; 47: 816-20.
    • (2004) Diabetologia , vol.47 , pp. 816-820
    • Civitarese, A.E.1    Jenkinson, C.P.2    Richardson, D.3
  • 33
    • 2942622680 scopus 로고    scopus 로고
    • Expression of key genes of fatty acid oxidation, including adiponectin receptors, in skeletal muscle of type 2 diabetic patients
    • Debard C, Laville M, Berbe V, et al. Expression of key genes of fatty acid oxidation, including adiponectin receptors, in skeletal muscle of type 2 diabetic patients. Diabetologia 2004; 47: 917-25.
    • (2004) Diabetologia , vol.47 , pp. 917-925
    • Debard, C.1    Laville, M.2    Berbe, V.3
  • 34
    • 0034641647 scopus 로고    scopus 로고
    • Adiponectin, an adipocyte-derived plasma protein, inhibits endothelial NF-kappaB signaling through a cAMP-dependent pathway
    • Ouchi N, Kihara S, Arita Y, et al. Adiponectin, an adipocyte-derived plasma protein, inhibits endothelial NF-kappaB signaling through a cAMP-dependent pathway. Circulation 2000; 102: 1296-301.
    • (2000) Circulation , vol.102 , pp. 1296-1301
    • Ouchi, N.1    Kihara, S.2    Arita, Y.3
  • 35
    • 17944365228 scopus 로고    scopus 로고
    • The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity
    • Yamauchi T, Kamon J, Waki H, et al. The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity. Nat Med 2001; 7: 941-6.
    • (2001) Nat Med , vol.7 , pp. 941-946
    • Yamauchi, T.1    Kamon, J.2    Waki, H.3
  • 36
    • 0036851817 scopus 로고    scopus 로고
    • Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase
    • Yamauchi T, Kamon J, Minokoshi Y, et al. Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase. Nat Med 2002; 8: 1288-95.
    • (2002) Nat Med , vol.8 , pp. 1288-1295
    • Yamauchi, T.1    Kamon, J.2    Minokoshi, Y.3
  • 37
    • 0037122766 scopus 로고    scopus 로고
    • Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase
    • Minokoshi Y, Kim YB, Peroni OD, et al. Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase. Nature 2002; 415: 339-43.
    • (2002) Nature , vol.415 , pp. 339-343
    • Minokoshi, Y.1    Kim, Y.B.2    Peroni, O.D.3
  • 38
    • 0037059013 scopus 로고    scopus 로고
    • Enhanced muscle fat oxidation and glucose transport by ACRP30 globular domain: Acetyl-CoA carboxylase inhibition and AMP-activated protein kinase activation
    • Tomas E, Tsao TS, Saha AK, et al. Enhanced muscle fat oxidation and glucose transport by ACRP30 globular domain: acetyl-CoA carboxylase inhibition and AMP-activated protein kinase activation. Proc Natl Acad Sci USA 2002; 99: 16309-13.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 16309-16313
    • Tomas, E.1    Tsao, T.S.2    Saha, A.K.3
  • 39
    • 0033515761 scopus 로고    scopus 로고
    • Paradoxical decrease of an adipose-specific: Protein, adiponectin, in obesity
    • Arita Y, Kihara S, Ouchi N, et al. Paradoxical decrease of an adipose-specific: protein, adiponectin, in obesity. Biochem Biophys Res Commun 1999; 257: 79-83.
    • (1999) Biochem Biophys Res Commun , vol.257 , pp. 79-83
    • Arita, Y.1    Kihara, S.2    Ouchi, N.3
  • 40
    • 0034096988 scopus 로고    scopus 로고
    • Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients
    • Hotta K, Funahashi T, Arita Y, et al. Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients. Arterioscler Thromb Vasc Biol 2000; 20: 1595-9.
    • (2000) Arterioscler Thromb Vasc Biol , vol.20 , pp. 1595-1599
    • Hotta, K.1    Funahashi, T.2    Arita, Y.3
  • 41
    • 0033613545 scopus 로고    scopus 로고
    • Novel modulator for endothelial adhesion molecules: Adipocyte-derived plasma protein adiponectin
    • Ouchi N, Kihara S, Arita Y, et al. Novel modulator for endothelial adhesion molecules: adipocyte-derived plasma protein adiponectin. Circulation 1999; 100: 2473-6.
    • (1999) Circulation , vol.100 , pp. 2473-2476
    • Ouchi, N.1    Kihara, S.2    Arita, Y.3
  • 42
    • 0034999667 scopus 로고    scopus 로고
    • Hypoadiponectinemia in obesity and type 2 diabetes: Close association with insulin resistance and hyperinsulinemia
    • Weyer C, Funahashi T, Tanaka S, et al. Hypoadiponectinemia in obesity and type 2 diabetes: close association with insulin resistance and hyperinsulinemia. J Clin Endocrinol Metab 2001; 86: 1930-5.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 1930-1935
    • Weyer, C.1    Funahashi, T.2    Tanaka, S.3
  • 43
    • 0036266897 scopus 로고    scopus 로고
    • Plasma adiponectin concentration is associated with skeletal muscle insulin receptor tyrosine phosphorylation, and low plasma concentration precedes a decrease in whole-body insulin sensitivity in humans
    • Stefan N, Vozarova B, Funahashi T, et al. Plasma adiponectin concentration is associated with skeletal muscle insulin receptor tyrosine phosphorylation, and low plasma concentration precedes a decrease in whole-body insulin sensitivity in humans. Diabetes 2002; 51: 1884-8.
    • (2002) Diabetes , vol.51 , pp. 1884-1888
    • Stefan, N.1    Vozarova, B.2    Funahashi, T.3
  • 44
    • 0036511213 scopus 로고    scopus 로고
    • ACRP30/adiponectin: An adipokine regulating glucose and lipid metabolism
    • Berg AH, Combs TP, Scherer PE. ACRP30/adiponectin: an adipokine regulating glucose and lipid metabolism. Trends Endocrinol Metab 2002; 13: 84-9.
    • (2002) Trends Endocrinol Metab , vol.13 , pp. 84-89
    • Berg, A.H.1    Combs, T.P.2    Scherer, P.E.3
  • 45
    • 0036349010 scopus 로고    scopus 로고
    • Correlation of the adipocytederived protein adiponectin with insulin resistance index and serum highdensity lipoprotein-cholesterol, independent of body mass index, in the Japanese population
    • Yamamoto Y, Hirose H, Saito I, et al. Correlation of the adipocytederived protein adiponectin with insulin resistance index and serum highdensity lipoprotein-cholesterol, independent of body mass index, in the Japanese population. Clin Sci 2002; 103: 137-42.
    • (2002) Clin Sci , vol.103 , pp. 137-142
    • Yamamoto, Y.1    Hirose, H.2    Saito, I.3
  • 46
    • 22244473951 scopus 로고    scopus 로고
    • Plasma adiponectin concentration in relation to severity of coronary atherosclerosis and cardiovascular risk factors in middle-aged men
    • Dunajska K, Milewicz A, Jedrzejuk D, et al. Plasma adiponectin concentration in relation to severity of coronary atherosclerosis and cardiovascular risk factors in middle-aged men. Endocrine 2004; 25: 215-21.
    • (2004) Endocrine , vol.25 , pp. 215-221
    • Dunajska, K.1    Milewicz, A.2    Jedrzejuk, D.3
  • 47
    • 0037230545 scopus 로고    scopus 로고
    • Decreased plasma adiponectin concentration in patients with essential hypertension
    • Adamczak M, Wiecek A, Funahashi T, et al. Decreased plasma adiponectin concentration in patients with essential hypertension. Am J Hypertens 2003; 16: 72-5.
    • (2003) Am J Hypertens , vol.16 , pp. 72-75
    • Adamczak, M.1    Wiecek, A.2    Funahashi, T.3
  • 48
    • 0037031088 scopus 로고    scopus 로고
    • Adiponectin and development of type 2 diabetes in the Pima Indian population
    • Lindsay RS, Funahashi T, Hanson RL, et al. Adiponectin and development of type 2 diabetes in the Pima Indian population. Lancet 2002; 360: 57-8.
    • (2002) Lancet , vol.360 , pp. 57-58
    • Lindsay, R.S.1    Funahashi, T.2    Hanson, R.L.3
  • 49
    • 1642467862 scopus 로고    scopus 로고
    • Decreased serum levels of adiponectin are a risk factor for the progression to type 2 diabetes in the Japanese Population: The Funagata study
    • Daimon M, Oizumi T, Saitoh T, et al. Decreased serum levels of adiponectin are a risk factor for the progression to type 2 diabetes in the Japanese Population: the Funagata study. Diabetes Care 2003; 26: 2015-20.
    • (2003) Diabetes Care , vol.26 , pp. 2015-2020
    • Daimon, M.1    Oizumi, T.2    Saitoh, T.3
  • 50
    • 4344665855 scopus 로고    scopus 로고
    • Adiponectin and the development of type 2 diabetes: The atherosclerosis risk in communities study
    • Duncan BB, Schmidt MI, Pankow JS, et al. Adiponectin and the development of type 2 diabetes: the atherosclerosis risk in communities study. Diabetes Care 2004; 53: 2473-8.
    • (2004) Diabetes Care , vol.53 , pp. 2473-2478
    • Duncan, B.B.1    Schmidt, M.I.2    Pankow, J.S.3
  • 51
    • 0344844389 scopus 로고    scopus 로고
    • Plasma adiponectin is an independent predictor of type 2 diabetes in Asian indians
    • Snehalatha C, Mukesh B, Simon M, et al. Plasma adiponectin is an independent predictor of type 2 diabetes in Asian indians. Diabetes Care 2003; 26: 3226-9.
    • (2003) Diabetes Care , vol.26 , pp. 3226-3229
    • Snehalatha, C.1    Mukesh, B.2    Simon, M.3
  • 52
    • 0037452139 scopus 로고    scopus 로고
    • Adiponectin and protection against type 2 diabetes mellitus
    • Spranger J, Kroke A, Möhlig M, et al. Adiponectin and protection against type 2 diabetes mellitus. Lancet 2003; 361: 226-8.
    • (2003) Lancet , vol.361 , pp. 226-228
    • Spranger, J.1    Kroke, A.2    Möhlig, M.3
  • 53
    • 0035663963 scopus 로고    scopus 로고
    • Endogenous glucose production is inhibited by the adipose-derived protein Acrp30
    • Combs TP, Berg AH, Obici S, et al. Endogenous glucose production is inhibited by the adipose-derived protein Acrp30. J Clin Invest 2001; 108: 1875-81.
    • (2001) J Clin Invest , vol.108 , pp. 1875-1881
    • Combs, T.P.1    Berg, A.H.2    Obici, S.3
  • 54
    • 0842313004 scopus 로고    scopus 로고
    • Decreased plasma adiponectin concentrations are closely related to hepatic fat content and hepatic insulin resistance in pioglitazone-treated type 2 diabetic patients
    • Bajaj M, Suraamornkul S, Piper P, et al. Decreased plasma adiponectin concentrations are closely related to hepatic fat content and hepatic insulin resistance in pioglitazone-treated type 2 diabetic patients. J Clin Endocrinol Metab 2004; 89: 200-6.
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 200-206
    • Bajaj, M.1    Suraamornkul, S.2    Piper, P.3
  • 56
    • 33644585600 scopus 로고    scopus 로고
    • Plasma adiponectin concentration and tumor necrosis factor-alpha system activity in lean non-diabetic offspring of type 2 diabetic subjects
    • Kowalska I, Straczkowski M, Nikołajuk A, et al. Plasma adiponectin concentration and tumor necrosis factor-alpha system activity in lean non-diabetic offspring of type 2 diabetic subjects. Eur J Endocrinol 2006; 154: 319-24.
    • (2006) Eur J Endocrinol , vol.154 , pp. 319-324
    • Kowalska, I.1    Straczkowski, M.2    Nikołajuk, A.3
  • 57
    • 0034891684 scopus 로고    scopus 로고
    • Weight reduction increases plasma levels of an adipose-derived anti-inflammatory protein, adiponectin
    • Yang W, Lee W, Funahashi T, et al. Weight reduction increases plasma levels of an adipose-derived anti-inflammatory protein, adiponectin. J Clin Endocrinol Metab 2001; 86: 3815-9.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 3815-3819
    • Yang, W.1    Lee, W.2    Funahashi, T.3
  • 58
    • 0036785619 scopus 로고    scopus 로고
    • Adiponectin is not altered with exercise training despite enhanced insulin action
    • Hulver MW, Zheng D, Tanner CJ, et al. Adiponectin is not altered with exercise training despite enhanced insulin action. Am J Physiol Endocrinol Metab 2002; 283: E861-5.
    • (2002) Am J Physiol Endocrinol Metab , vol.283
    • Hulver, M.W.1    Zheng, D.2    Tanner, C.J.3
  • 59
    • 27344456029 scopus 로고    scopus 로고
    • Aerobic exercise training improves insulin sensitivity without changes in body weight, body fat, adiponectin, and inflammatory markers in overweight and obese girls
    • Nassis GP, Papantakou K, Skenderi K, et al. Aerobic exercise training improves insulin sensitivity without changes in body weight, body fat, adiponectin, and inflammatory markers in overweight and obese girls. Metabolism 2005; 54: 1472-9.
    • (2005) Metabolism , vol.54 , pp. 1472-1479
    • Nassis, G.P.1    Papantakou, K.2    Skenderi, K.3
  • 60
    • 2542469639 scopus 로고    scopus 로고
    • Plasma adiponectin concentrations do not increase in association with moderate weight loss in insulin-resistant, obese women
    • Abbasi F, Lamendola C, McLaughlin T, et al. Plasma adiponectin concentrations do not increase in association with moderate weight loss in insulin-resistant, obese women. Metabolism 2004; 53: 280-3.
    • (2004) Metabolism , vol.53 , pp. 280-283
    • Abbasi, F.1    Lamendola, C.2    McLaughlin, T.3
  • 61
    • 24144497040 scopus 로고    scopus 로고
    • Circulating adiponectin reflects severity of liver disease but not insulin sensitivity in liver cirrhosis
    • Kaser S, Moschen A, Kaser A, et al. Circulating adiponectin reflects severity of liver disease but not insulin sensitivity in liver cirrhosis. J Intern Med 2005; 258: 274-80.
    • (2005) J Intern Med , vol.258 , pp. 274-280
    • Kaser, S.1    Moschen, A.2    Kaser, A.3
  • 62
    • 21444439097 scopus 로고    scopus 로고
    • Does adiponectin explain the lower insulin sensitivity and hyperinsulinemia of African-American children?
    • Bacha F, Saad R, Gungor N, Arslanian SA. Does adiponectin explain the lower insulin sensitivity and hyperinsulinemia of African-American children? Pediatr Diabetes 2005; 6: 100-2.
    • (2005) Pediatr Diabetes , vol.6 , pp. 100-102
    • Bacha, F.1    Saad, R.2    Gungor, N.3    Arslanian, S.A.4
  • 63
    • 26244458678 scopus 로고    scopus 로고
    • Plasma adiponectin levels are associated with insulin resistance, but do not predict future risk of coronary heart disease in women
    • Lawlor DA, Davey Smith G, Ebrahim S, et al. Plasma adiponectin levels are associated with insulin resistance, but do not predict future risk of coronary heart disease in women. J Clin Endocrinol Metab 2005; 90: 5677-83.
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 5677-5683
    • Lawlor, D.A.1    Davey Smith, G.2    Ebrahim, S.3
  • 64
    • 27744597211 scopus 로고    scopus 로고
    • Adiponectin represses gluconeogenesis independent of insulin in hepatocytes
    • Zhou H, Song X, Briggs M, et al. Adiponectin represses gluconeogenesis independent of insulin in hepatocytes. Biochem Biophys Res Commun 2005; 338: 793-9.
    • (2005) Biochem Biophys Res Commun , vol.338 , pp. 793-799
    • Zhou, H.1    Song, X.2    Briggs, M.3
  • 65
    • 0034014647 scopus 로고    scopus 로고
    • An adipocyte-derived plasma protein, adiponectin, adheres to injured vascular walls
    • Okamoto Y, Arita Y, Nishida M, et al. An adipocyte-derived plasma protein, adiponectin, adheres to injured vascular walls. Horm Metab Res 2000; 32: 47-50.
    • (2000) Horm Metab Res , vol.32 , pp. 47-50
    • Okamoto, Y.1    Arita, Y.2    Nishida, M.3
  • 66
    • 0035957040 scopus 로고    scopus 로고
    • Adipocyte-derived plasma protein, adiponectin, suppresses lipid accumulation and class A scavenger receptor expression in human monocyte-derived macrophages
    • Ouchi N, Kihara S, Arita Y, et al. Adipocyte-derived plasma protein, adiponectin, suppresses lipid accumulation and class A scavenger receptor expression in human monocyte-derived macrophages. Circulation 2001; 103: 1057-63.
    • (2001) Circulation , vol.103 , pp. 1057-1063
    • Ouchi, N.1    Kihara, S.2    Arita, Y.3
  • 67
    • 34347369616 scopus 로고    scopus 로고
    • Plasma adiponectin and E-selectin concentrations in patients with coronary heart disease and newly diagnosed disturbances of glucose metabolism
    • Kowalska I, Straczkowski M, Nikołajuk A, et al. Plasma adiponectin and E-selectin concentrations in patients with coronary heart disease and newly diagnosed disturbances of glucose metabolism. Adv Med Sci 2006; 51: 94-7.
    • (2006) Adv Med Sci , vol.51 , pp. 94-97
    • Kowalska, I.1    Straczkowski, M.2    Nikołajuk, A.3
  • 68
    • 0038293399 scopus 로고    scopus 로고
    • Relationship of adiponectin to body fat distribution, insulin sensitivity and plasma lipoproteins: Evidence for independent roles of age and sex
    • Cnop M, Havel PJ, Utzschneider KM, et al. Relationship of adiponectin to body fat distribution, insulin sensitivity and plasma lipoproteins: evidence for independent roles of age and sex. Diabetologia 2003; 46: 459-69.
    • (2003) Diabetologia , vol.46 , pp. 459-469
    • Cnop, M.1    Havel, P.J.2    Utzschneider, K.M.3
  • 69
    • 0041519355 scopus 로고    scopus 로고
    • Adiponectin: Systemic contributor to insulin sensitivity
    • Pajvani UB, Scherer PE. Adiponectin: systemic contributor to insulin sensitivity. Curr Diab Rep 2003; 3: 207-13.
    • (2003) Curr Diab Rep , vol.3 , pp. 207-213
    • Pajvani, U.B.1    Scherer, P.E.2
  • 70
    • 0037312826 scopus 로고    scopus 로고
    • Plasma adiponectin concentrations predict insulin sensitivity of both glucose and lipid metabolism
    • Tschritter O, Fritsche A, Thamer C, et al. Plasma adiponectin concentrations predict insulin sensitivity of both glucose and lipid metabolism. Diabetes 2003; 52: 239-43.
    • (2003) Diabetes , vol.52 , pp. 239-243
    • Tschritter, O.1    Fritsche, A.2    Thamer, C.3
  • 71
    • 0036075053 scopus 로고    scopus 로고
    • Decreased plasma adiponectin concentrations in women with dyslipidemia
    • Matsubara M, Maruoka S, Katayose S. Decreased plasma adiponectin concentrations in women with dyslipidemia. J Clin Endocrinol Metab 2002; 87: 2764-9.
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 2764-2769
    • Matsubara, M.1    Maruoka, S.2    Katayose, S.3
  • 72
    • 23044508361 scopus 로고    scopus 로고
    • The relationships of adiponectin with insulin and lipids are strengthened with increasing adiposity
    • Martin LJ, Woo JG, Daniels SR, et al. The relationships of adiponectin with insulin and lipids are strengthened with increasing adiposity. J Clin Endocrinol Metab 2005; 90: 4255-9.
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 4255-4259
    • Martin, L.J.1    Woo, J.G.2    Daniels, S.R.3
  • 73
    • 33646413654 scopus 로고    scopus 로고
    • Possible role of adiponectin and insulin sensitivity in mediating the favorable effects of lower body fat mass on blood lipids
    • Buemann B, Astrup A, Pedersen O, et al. Possible role of adiponectin and insulin sensitivity in mediating the favorable effects of lower body fat mass on blood lipids. J Clin Endocrinol Metab 2006; 91: 1698-704.
    • (2006) J Clin Endocrinol Metab , vol.91 , pp. 1698-1704
    • Buemann, B.1    Astrup, A.2    Pedersen, O.3
  • 74
    • 2942670648 scopus 로고    scopus 로고
    • Adiponectin relationship with lipid metabolism is independent of body fat mass: Evidence from both cross-sectional and intervention studies
    • Baratta R, Amato S, Degano C, et al. Adiponectin relationship with lipid metabolism is independent of body fat mass: evidence from both cross-sectional and intervention studies. J Clin Endocrinol Metab 2004; 89: 2665-71.
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 2665-2671
    • Baratta, R.1    Amato, S.2    Degano, C.3
  • 75
    • 23844549872 scopus 로고    scopus 로고
    • Circulating adiponectin levels are associated with better glycemic control, more favorable lipid profile, and reduced inflammation in women with type 2 diabetes
    • Mantzoros CS, Li T, Manson JE, et al. Circulating adiponectin levels are associated with better glycemic control, more favorable lipid profile, and reduced inflammation in women with type 2 diabetes. J Clin Endocrinol Metab 2005; 90: 4542-8.
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 4542-4548
    • Mantzoros, C.S.1    Li, T.2    Manson, J.E.3
  • 76
    • 0037135523 scopus 로고    scopus 로고
    • Disruption of adiponectin causes insulin resistance and neointimal formation
    • Kubota N, Terauchi Y, Yamauchi T, et al. Disruption of adiponectin causes insulin resistance and neointimal formation. J Biol Chem 2002; 277: 25863-6.
    • (2002) J Biol Chem , vol.277 , pp. 25863-25866
    • Kubota, N.1    Terauchi, Y.2    Yamauchi, T.3
  • 77
    • 2442659256 scopus 로고    scopus 로고
    • Adiponectin acts in the brain to decrease body weight
    • Qi Y, Takahashi N, Hileman SM, et al. Adiponectin acts in the brain to decrease body weight. Nat Med 2004; 10: 524-9.
    • (2004) Nat Med , vol.10 , pp. 524-529
    • Qi, Y.1    Takahashi, N.2    Hileman, S.M.3
  • 78
    • 0041818404 scopus 로고    scopus 로고
    • Adiponectin levels do not change with moderate dietary induced weight loss and exercise in obese postmenopausal women
    • Ryan AS, Nicklas BJ, Berman DM, et al. Adiponectin levels do not change with moderate dietary induced weight loss and exercise in obese postmenopausal women. Intern J Obesity 2003; 27: 1066-71.
    • (2003) Intern J Obesity , vol.27 , pp. 1066-1071
    • Ryan, A.S.1    Nicklas, B.J.2    Berman, D.M.3
  • 79
    • 28744439955 scopus 로고    scopus 로고
    • Adiponectin is functionally active in human islets but does not affect insulin secretory function or beta-cell lipoapoptosis
    • Staiger K, Stefan N, Staiger H, et al. Adiponectin is functionally active in human islets but does not affect insulin secretory function or beta-cell lipoapoptosis. J Clin Endocrinol Metab 2005; 90: 6707-13.
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 6707-6713
    • Staiger, K.1    Stefan, N.2    Staiger, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.