-
1
-
-
0034076660
-
Fuel selection in human skeletal muscle in insulin resistance: A reexamination
-
Kelley DE, Mandarino LJ (2000) Fuel selection in human skeletal muscle in insulin resistance: a reexamination. Diabetes 49:677-683
-
(2000)
Diabetes
, vol.49
, pp. 677-683
-
-
Kelley, D.E.1
Mandarino, L.J.2
-
2
-
-
0027946529
-
Impaired free fatty acid utilization by skeletal muscle in non-insulin-dependent diabetes mellitus
-
Kelley DE, Simoneau JA (1994) Impaired free fatty acid utilization by skeletal muscle in non-insulin-dependent diabetes mellitus. J Clin Invest 94:2349-2356
-
(1994)
J Clin Invest
, vol.94
, pp. 2349-2356
-
-
Kelley, D.E.1
Simoneau, J.A.2
-
3
-
-
0017077182
-
Free fatty acid oxidation by forearm muscle at rest, and evidence for an intramuscular lipid pool in the human forearm
-
Dagenais GR, Tancredi RG, Zierler KL (1976) Free fatty acid oxidation by forearm muscle at rest, and evidence for an intramuscular lipid pool in the human forearm. J Clin Invest 58:421-431
-
(1976)
J Clin Invest
, vol.58
, pp. 421-431
-
-
Dagenais, G.R.1
Tancredi, R.G.2
Zierler, K.L.3
-
4
-
-
0033856104
-
Plasma FFA utilization and fatty acid-binding protein content are diminished in Type 2 diabetic muscle
-
Blaak EE, Wagenmakers AJ, Glatz JF et al. (2000) Plasma FFA utilization and fatty acid-binding protein content are diminished in Type 2 diabetic muscle. Am J Physiol Endocrinol Metab 279:E146-E154
-
(2000)
Am J Physiol Endocrinol Metab
, vol.279
-
-
Blaak, E.E.1
Wagenmakers, A.J.2
Glatz, J.F.3
-
5
-
-
0033645223
-
Impaired oxidation of plasma-derived fatty acids in Type 2 diabetic subjects during moderate-intensity exercise
-
Blaak EE, van Aggel-Leijssen DP, Wagenmakers AJ, Saris WH, van Baak MA (2000) Impaired oxidation of plasma-derived fatty acids in Type 2 diabetic subjects during moderate-intensity exercise. Diabetes 49:2102-2107
-
(2000)
Diabetes
, vol.49
, pp. 2102-2107
-
-
Blaak, E.E.1
Van Aggel-Leijssen, D.P.2
Wagenmakers, A.J.3
Saris, W.H.4
Van Baak, M.A.5
-
6
-
-
0036092239
-
Banting lecture 2001: Dysregulation of fatty acid metabolism in the etiology of Type 2 diabetes
-
McGarry JD (2002) Banting lecture 2001: dysregulation of fatty acid metabolism in the etiology of Type 2 diabetes. Diabetes 51:7-18
-
(2002)
Diabetes
, vol.51
, pp. 7-18
-
-
McGarry, J.D.1
-
7
-
-
0042160182
-
The role of intramuscular lipid in insulin resistance
-
Hegarty BD, Furler SM, Ye J, Cooney GJ, Kraegen EW (2003) The role of intramuscular lipid in insulin resistance. Acta Physiol Scand 178:373-383
-
(2003)
Acta Physiol Scand
, vol.178
, pp. 373-383
-
-
Hegarty, B.D.1
Furler, S.M.2
Ye, J.3
Cooney, G.J.4
Kraegen, E.W.5
-
8
-
-
0033927667
-
Cellular mechanisms of insulin resistance
-
Shulman GI (2000) Cellular mechanisms of insulin resistance. J Clin Invest 106:171-176
-
(2000)
J Clin Invest
, vol.106
, pp. 171-176
-
-
Shulman, G.I.1
-
9
-
-
0036788293
-
Dysfunction of mitochondria in human skeletal muscle in Type 2 diabetes
-
Kelley DE, He J, Menshikova EV, Ritov VB (2002) Dysfunction of mitochondria in human skeletal muscle in Type 2 diabetes. Diabetes 51:2944-2950
-
(2002)
Diabetes
, vol.51
, pp. 2944-2950
-
-
Kelley, D.E.1
He, J.2
Menshikova, E.V.3
Ritov, V.B.4
-
10
-
-
0037477855
-
Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1
-
Patti ME, Butte AJ, Crunkhorn S et al. (2003) Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1. Proc Natl Acad Sci USA 100:8466-8471
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 8466-8471
-
-
Patti, M.E.1
Butte, A.J.2
Crunkhorn, S.3
-
11
-
-
0038054341
-
PGC-1 alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes
-
Mootha VK, Lindgren CM, Eriksson KF et al. (2003) PGC-1 alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes. Nat Genet 34:267-273
-
(2003)
Nat Genet
, vol.34
, pp. 267-273
-
-
Mootha, V.K.1
Lindgren, C.M.2
Eriksson, K.F.3
-
12
-
-
0038025371
-
Mitochondrial dysfunction in the elderly: Possible role in insulin resistance
-
Petersen KF, Befroy D, Dufour S et al. (2003) Mitochondrial dysfunction in the elderly: possible role in insulin resistance. Science 300:1140-1142
-
(2003)
Science
, vol.300
, pp. 1140-1142
-
-
Petersen, K.F.1
Befroy, D.2
Dufour, S.3
-
13
-
-
0032752951
-
Markers of capacity to utilize fatty acids in human skeletal muscle: Relation to insulin resistance and obesity and effects of weight loss
-
Simoneau JA, Veerkamp JH, Turcotte LP, Kelley DE (1999) Markers of capacity to utilize fatty acids in human skeletal muscle: relation to insulin resistance and obesity and effects of weight loss. FASEB J 13:2051-2060
-
(1999)
FASEB J
, vol.13
, pp. 2051-2060
-
-
Simoneau, J.A.1
Veerkamp, J.H.2
Turcotte, L.P.3
Kelley, D.E.4
-
14
-
-
0035852760
-
Proteolytic cleavage product of 30-kDa adipocyte complement-related protein increases fatty acid oxidation in muscle and causes weight loss in mice
-
Fruebis J, Tsao TS, Javorschi S et al. (2001) Proteolytic cleavage product of 30-kDa adipocyte complement-related protein increases fatty acid oxidation in muscle and causes weight loss in mice. Proc Natl Acad Sci USA 98:2005-2010
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 2005-2010
-
-
Fruebis, J.1
Tsao, T.S.2
Javorschi, S.3
-
15
-
-
0037059013
-
Enhanced muscle fat oxidation and glucose transport by ACRP30 globular domain: Acetyl-CoA carboxylase inhibition and AMP-activated protein kinase activation
-
Tomas E, Tsao TS, Saha AK et al. (2002) Enhanced muscle fat oxidation and glucose transport by ACRP30 globular domain: acetyl-CoA carboxylase inhibition and AMP-activated protein kinase activation. Proc Natl Acad Sci USA 99:16309-16313
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 16309-16313
-
-
Tomas, E.1
Tsao, T.S.2
Saha, A.K.3
-
16
-
-
0036511213
-
ACRP30/ adiponectin: An adipokine regulating glucose and lipid metabolism
-
Berg AH, Combs TP, Scherer PE (2002) ACRP30/ adiponectin: an adipokine regulating glucose and lipid metabolism. Trends Endocrinol Metab 13:84-89
-
(2002)
Trends Endocrinol Metab
, vol.13
, pp. 84-89
-
-
Berg, A.H.1
Combs, T.P.2
Scherer, P.E.3
-
17
-
-
0037494960
-
Cloning of adiponectin receptors that mediate antidiabetic metabolic effects
-
I7. Yamauchi T, Kamon J, Ito Y et al. (2003) Cloning of adiponectin receptors that mediate antidiabetic metabolic effects. Nature 423:762-769
-
(2003)
Nature
, vol.423
, pp. 762-769
-
-
Yamauchi, T.1
Kamon, J.2
Ito, Y.3
-
18
-
-
0030037364
-
Acute regulation by insulin of phosphatidylinositol-3-kinase, Rad, Glut 4, and lipoprotein lipase mRNA levels in human muscle
-
Laville M, Auboeuf D, Khalfallah Y, Vega N, Riou JP, Vidal H (1996) Acute regulation by insulin of phosphatidylinositol-3-kinase, Rad, Glut 4, and lipoprotein lipase mRNA levels in human muscle. J Clin Invest 98:43-49
-
(1996)
J Clin Invest
, vol.98
, pp. 43-49
-
-
Laville, M.1
Auboeuf, D.2
Khalfallah, Y.3
Vega, N.4
Riou, J.P.5
Vidal, H.6
-
19
-
-
0035029812
-
Regulation by insulin of gene expression in human skeletal muscle and adipose tissue. Evidence for specific defects in Type 2 diabetes
-
Ducluzeau PH, Perretti N, Laville M et al. (2001) Regulation by insulin of gene expression in human skeletal muscle and adipose tissue. Evidence for specific defects in Type 2 diabetes. Diabetes 50:1134-1142
-
(2001)
Diabetes
, vol.50
, pp. 1134-1142
-
-
Ducluzeau, P.H.1
Perretti, N.2
Laville, M.3
-
20
-
-
0023277545
-
Single-step method of RNA isolation by acid guanidinium thiocyanate-phenolchloroform extraction
-
Chomczynski P, Sacchi N (1987) Single-step method of RNA isolation by acid guanidinium thiocyanate-phenolchloroform extraction. Anal Biochem 162:156-159
-
(1987)
Anal Biochem
, vol.162
, pp. 156-159
-
-
Chomczynski, P.1
Sacchi, N.2
-
21
-
-
0038724906
-
Microarray profiling of human skeletal muscle reveals that insulin regulates approximately 800 genes during a hyperinsulinemic clamp
-
Rome S, Clement K, Rabasa-Lhoret R et al. (2003) Microarray profiling of human skeletal muscle reveals that insulin regulates approximately 800 genes during a hyperinsulinemic clamp. J Biol Chem 278:18063-18068
-
(2003)
J Biol Chem
, vol.278
, pp. 18063-18068
-
-
Rome, S.1
Clement, K.2
Rabasa-Lhoret, R.3
-
22
-
-
0028842531
-
Impaired activity and gene expression of hexokinase II in muscle from non-insulin-dependent diabetes mellitus patients
-
Vestergaard H, Bjorbaek C, Hansen T, Larsen FS, Granner DK, Pedersen O (1995) Impaired activity and gene expression of hexokinase II in muscle from non-insulin-dependent diabetes mellitus patients. J Clin Invest 96:2639-2645
-
(1995)
J Clin Invest
, vol.96
, pp. 2639-2645
-
-
Vestergaard, H.1
Bjorbaek, C.2
Hansen, T.3
Larsen, F.S.4
Granner, D.K.5
Pedersen, O.6
-
23
-
-
0033667510
-
Fatty acid transport protein-1 mRNA expression in skeletal muscle and in adipose tissue in humans
-
Binnert C, Koistinen HA, Martin G et al. (2000) Fatty acid transport protein-1 mRNA expression in skeletal muscle and in adipose tissue in humans. Am J Physiol Endocrinol Metab 279:E1072-E1079
-
(2000)
Am J Physiol Endocrinol Metab
, vol.279
-
-
Binnert, C.1
Koistinen, H.A.2
Martin, G.3
-
24
-
-
0034717940
-
Fatty acid import into mitochondria
-
Kerner J, Hoppel C (2000) Fatty acid import into mitochondria. Biochim Biophys Acta 1486:1-17
-
(2000)
Biochim Biophys Acta
, vol.1486
, pp. 1-17
-
-
Kerner, J.1
Hoppel, C.2
-
25
-
-
0037900979
-
Minireview: Lipid metabolism, metabolic diseases, and peroxisome proliferator-activated receptors
-
Lee CH, Olson P, Evans RM (2003) Minireview: lipid metabolism, metabolic diseases, and peroxisome proliferator-activated receptors. Endocrinology 144:2201-2207
-
(2003)
Endocrinology
, vol.144
, pp. 2201-2207
-
-
Lee, C.H.1
Olson, P.2
Evans, R.M.3
-
27
-
-
0037593949
-
Mitofusin-2 determines mitochondrial network architecture and mitochondrial metabolism. A novel regulatory mechanism altered in obesity
-
Bach D, Pich S, Soriano FX et al. (2003) Mitofusin-2 determines mitochondrial network architecture and mitochondrial metabolism. A novel regulatory mechanism altered in obesity. J Biol Chem 278:17190-17197
-
(2003)
J Biol Chem
, vol.278
, pp. 17190-17197
-
-
Bach, D.1
Pich, S.2
Soriano, F.X.3
-
28
-
-
0037238247
-
Insulin resistance in Type 2 diabetes: Association with truncal obesity, impaired fitness, and atypical malonyl coenzyme a regulation
-
Bavenholm PN, Kuhl J, Pigon J, Saha AK, Ruderman NB, Efendic S (2003) Insulin resistance in Type 2 diabetes: association with truncal obesity, impaired fitness, and atypical malonyl coenzyme A regulation. J Clin Endocrinol Metab 88:82-87
-
(2003)
J Clin Endocrinol Metab
, vol.88
, pp. 82-87
-
-
Bavenholm, P.N.1
Kuhl, J.2
Pigon, J.3
Saha, A.K.4
Ruderman, N.B.5
Efendic, S.6
-
29
-
-
0033948495
-
Fatty acid oxidation and the regulation of malonyl-CoA in human muscle
-
Bavenholm PN, Pigon J, Saha AK, Ruderman NB, Efendic S (2000) Fatty acid oxidation and the regulation of malonyl-CoA in human muscle. Diabetes 49:1078-1083
-
(2000)
Diabetes
, vol.49
, pp. 1078-1083
-
-
Bavenholm, P.N.1
Pigon, J.2
Saha, A.K.3
Ruderman, N.B.4
Efendic, S.5
-
30
-
-
0036896836
-
Malonyl coenzyme a and the regulation of functional carnitine palmitoyltransferase-1 activity and fat oxidation in human skeletal muscle
-
Rasmussen BB, Holmback UC, Volpi E, Morio-Liondore B, Paddon-Jones D, Wolfe RR (2002) Malonyl coenzyme A and the regulation of functional carnitine palmitoyltransferase-1 activity and fat oxidation in human skeletal muscle. J Clin Invest 110:1687-1693
-
(2002)
J Clin Invest
, vol.110
, pp. 1687-1693
-
-
Rasmussen, B.B.1
Holmback, U.C.2
Volpi, E.3
Morio-Liondore, B.4
Paddon-Jones, D.5
Wolfe, R.R.6
-
31
-
-
17944365228
-
The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity
-
Yamauchi T, Kamon J, Waki H et al. (2001) The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity. Nat Med 7:941-946
-
(2001)
Nat Med
, vol.7
, pp. 941-946
-
-
Yamauchi, T.1
Kamon, J.2
Waki, H.3
-
32
-
-
0036631904
-
Exercise and insulin increase muscle fatty acid uptake by recruiting putative fatty acid transporters to the sarcolemma
-
Glatz JF, Bonen A, Luiken JJ (2002) Exercise and insulin increase muscle fatty acid uptake by recruiting putative fatty acid transporters to the sarcolemma. Curr Opin Clin Nutr Metab Care 5:365-370
-
(2002)
Curr Opin Clin Nutr Metab Care
, vol.5
, pp. 365-370
-
-
Glatz, J.F.1
Bonen, A.2
Luiken, J.J.3
-
33
-
-
0034823750
-
Insulin increases FA uptake and esterification but reduces lipid utilization in isolated contracting muscle
-
Dyck DJ, Steinberg G, Bonen A (2001) Insulin increases FA uptake and esterification but reduces lipid utilization in isolated contracting muscle. Am J Physiol Endocrinol Metab 281:E600-E607
-
(2001)
Am J Physiol Endocrinol Metab
, vol.281
-
-
Dyck, D.J.1
Steinberg, G.2
Bonen, A.3
-
34
-
-
0038271638
-
Effect of insulin on human skeletal muscle mitochondrial ATP production, protein synthesis, and mRNA transcripts
-
Stump CS, Short KR, Bigelow ML, Schimke JM, Nair KS (2003) Effect of insulin on human skeletal muscle mitochondrial ATP production, protein synthesis, and mRNA transcripts. Proc Natl Acad Sci USA 100:7996-8001
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 7996-8001
-
-
Stump, C.S.1
Short, K.R.2
Bigelow, M.L.3
Schimke, J.M.4
Nair, K.S.5
-
35
-
-
0034961658
-
Fuel-sensing mechanisms integrating lipid and carbohydrate utilization
-
Sugden MC, Bulmer K, Holness MJ (2001) Fuel-sensing mechanisms integrating lipid and carbohydrate utilization. Biochem Soc Trans 29:272-278
-
(2001)
Biochem Soc Trans
, vol.29
, pp. 272-278
-
-
Sugden, M.C.1
Bulmer, K.2
Holness, M.J.3
-
36
-
-
0027303280
-
Expression of the major insulin regulatable glucose transporter (GLUT4) in skeletal muscle of noninsulin-dependent diabetic patients and healthy subjects before and after insulin infusion
-
Andersen PH, Lund S, Vestergaard H, Junker S, Kahn BB, Eedersen O (1993) Expression of the major insulin regulatable glucose transporter (GLUT4) in skeletal muscle of noninsulin-dependent diabetic patients and healthy subjects before and after insulin infusion. J Clin Endocrinol Metab 77:27-32
-
(1993)
J Clin Endocrinol Metab
, vol.77
, pp. 27-32
-
-
Andersen, P.H.1
Lund, S.2
Vestergaard, H.3
Junker, S.4
Kahn, B.B.5
Eedersen, O.6
-
37
-
-
0031938843
-
Insulin-induced hexokinase II expression is reduced in obesity and NIDDM
-
Pendergrass M, Koval J, Vogt C et al. (1998) Insulin-induced hexokinase II expression is reduced in obesity and NIDDM. Diabetes 47:387-389
-
(1998)
Diabetes
, vol.47
, pp. 387-389
-
-
Pendergrass, M.1
Koval, J.2
Vogt, C.3
|