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Volumn 31, Issue 4, 2009, Pages 369-375

A concise review: Antioxidant effects and bioactive constituents of grape

Author keywords

Antioxidants; Free radicals; Vitis Vinifera

Indexed keywords

ACID; ALPHA TOCOPHEROL; ANTINEOPLASTIC METAL COMPLEX; ANTIOXIDANT; ASCORBIC ACID; BETA CAROTENE; CALCIUM; CARBOHYDRATE; CATECHIN; EPICATECHIN; FAT; FLAVONOID; FREE RADICAL; GALLIC ACID; KAEMPFEROL; METHOTREXATE; MYRICETIN; PHOSPHORUS; POLYPHENOL DERIVATIVE; POTASSIUM; PROANTHOCYANIDIN DERIVATIVE; PROCYANIDIN DERIVATIVE; PROTEIN; QUERCETIN; RESVERATROL; RETINOL; SODIUM; UNINDEXED DRUG; VITIS VINIFERA EXTRACT; WATER;

EID: 75649116484     PISSN: 1300199X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (14)

References (47)
  • 1
    • 33744478401 scopus 로고    scopus 로고
    • Free radical theory of aging: An update: increasing the functional life span
    • Harman D. Free radical theory of aging: an update: increasing the functional life span. Ann NY Acad Sci 2006; 1067:10-21.
    • (2006) Ann NY Acad Sci , vol.1067 , pp. 10-21
    • Harman, D.1
  • 2
    • 0026636441 scopus 로고    scopus 로고
    • Halliwell B, Gutteridge JM, Cross CE.Free radicals, antioxidants and human disease; where are we now? J Lab Clin Med 1992; 199 : 598.620.
    • Halliwell B, Gutteridge JM, Cross CE.Free radicals, antioxidants and human disease; where are we now? J Lab Clin Med 1992; 199 : 598.620.
  • 3
    • 0030853262 scopus 로고    scopus 로고
    • Environmental pollution, pesticides, and prevention of cancer:misconceptions
    • Ames BN,Gold LS.Environmental pollution, pesticides, and prevention of cancer:misconceptions FASEB J 1997; 11:1041-1052.
    • (1997) FASEB J , vol.11 , pp. 1041-1052
    • Ames, B.N.1    Gold, L.S.2
  • 4
    • 43449125010 scopus 로고    scopus 로고
    • Disturbance of Pro.oxidative/Antioxidative Balance in Allogeneic Peripheral Blood Stem Cell Transplantation
    • Sari I, Çetin A, Kaynar L,et al. Disturbance of Pro.oxidative/Antioxidative Balance in Allogeneic Peripheral Blood Stem Cell Transplantation. Annals of Clinical Laboratory Science 2008 ;38: 120-125.
    • (2008) Annals of Clinical Laboratory Science , vol.38 , pp. 120-125
    • Sari, I.1    Çetin, A.2    Kaynar, L.3
  • 5
    • 69149111145 scopus 로고    scopus 로고
    • Changes in antioxidant status,blood pressure,and lymphocyte DNA Damage from Grape Juice Supplementation.Ann
    • Park YK,Lee SH,Park E,Kim JS,Kang MH.Changes in antioxidant status,blood pressure,and lymphocyte DNA Damage from Grape Juice Supplementation.Ann NY Acad Sci 2009;1171: 385-390 .
    • (2009) NY Acad Sci , vol.1171 , pp. 385-390
    • Park, Y.K.1    Lee, S.H.2    Park, E.3    Kim, J.S.4    Kang, M.H.5
  • 6
    • 69549115609 scopus 로고    scopus 로고
    • Bioactivity of grape chemicals for human health
    • Iriti M, Faoro F. Bioactivity of grape chemicals for human health. Nat Prod Commun 2009;4: 611-634.
    • (2009) Nat Prod Commun , vol.4 , pp. 611-634
    • Iriti, M.1    Faoro, F.2
  • 7
    • 51649111023 scopus 로고    scopus 로고
    • Grapes and Human Health:A Perspective
    • Pezzuto JM.Grapes and Human Health:A Perspective.J Agric Food Chem 2008;56: 6777-6784.
    • (2008) J Agric Food Chem , vol.56 , pp. 6777-6784
    • Pezzuto, J.M.1
  • 8
    • 68149155890 scopus 로고    scopus 로고
    • Biological and Medicinal Properties of Grapes and Their Bioactive Constituents: An Update
    • Yadav M, Jain S, Bhardwaj A, et al. Biological and Medicinal Properties of Grapes and Their Bioactive Constituents: An Update. J. Med Food 2009;12 : 473-484.
    • (2009) J. Med Food , vol.12 , pp. 473-484
    • Yadav, M.1    Jain, S.2    Bhardwaj, A.3
  • 9
    • 68149110700 scopus 로고    scopus 로고
    • Determination of boron in grape (Vitis vinifera) by azomethine H spectrophotometric method
    • Demir BS, Serindaǧ O. Determination of boron in grape (Vitis vinifera) by azomethine H spectrophotometric method. Eurasian J Anal Chem 2006; 1: 11-18.
    • (2006) Eurasian J Anal Chem , vol.1 , pp. 11-18
    • Demir, B.S.1    Serindaǧ, O.2
  • 10
    • 75649123635 scopus 로고    scopus 로고
    • Üzüm (Vitis Vinifera) Çekirdeǧinin Fenolik Bileşikleri ve Biyoaktif Özellikleri.Hasad Gida
    • Yil: 21 Sayi: 244
    • Saǧdiç O, Ekici L. Üzüm (Vitis Vinifera) Çekirdeǧinin Fenolik Bileşikleri ve Biyoaktif Özellikleri.Hasad Gida 2005;Yil: 21 Sayi: 244.
    • (2005)
    • Saǧdiç, O.1    Ekici, L.2
  • 11
    • 33746262973 scopus 로고    scopus 로고
    • Determination of antibacterial effects and total phenolic contents of grape (Vitis vinifera L.) seed extracts
    • Baydar NG, Sagdic O, Ozkan G, Çetin S. Determination of antibacterial effects and total phenolic contents of grape (Vitis vinifera L.) seed extracts. International Journal of Food Science and Technology 2006;41: 799-804.
    • (2006) International Journal of Food Science and Technology , vol.41 , pp. 799-804
    • Baydar, N.G.1    Sagdic, O.2    Ozkan, G.3    Çetin, S.4
  • 13
    • 69449092522 scopus 로고    scopus 로고
    • Review of the pharmacological effects of Vitis Vinifera and its bioactive compounds
    • Nasirsi-Asl M,Hosseinzadeh H. Review of the pharmacological effects of Vitis Vinifera and its bioactive compounds. Phytother Res 2009;23: 1197-1204.
    • (2009) Phytother Res , vol.23 , pp. 1197-1204
    • Nasirsi-Asl, M.1    Hosseinzadeh, H.2
  • 14
    • 33745968572 scopus 로고    scopus 로고
    • Grape phytochemicals: A bouquet of old and new nutraceuticals for human health
    • Iriti M, Faoro F. Grape phytochemicals: A bouquet of old and new nutraceuticals for human health. Med Hypothesis 2006;67: 833-838.
    • (2006) Med Hypothesis , vol.67 , pp. 833-838
    • Iriti, M.1    Faoro, F.2
  • 16
    • 33646521729 scopus 로고    scopus 로고
    • Flavonols in grapes, grape products and wines; Burden, profile and influential parameters
    • Makris P, Kallithraka S, Kefalas P. Flavonols in grapes, grape products and wines; Burden, profile and influential parameters, Journal of Food Composition and Analysis 2006;19 : 396-404.
    • (2006) Journal of Food Composition and Analysis , vol.19 , pp. 396-404
    • Makris, P.1    Kallithraka, S.2    Kefalas, P.3
  • 17
    • 0030956480 scopus 로고    scopus 로고
    • Oxygen free radical scavenging abilities of vitamins C and E, and a grape seed proanthocyanidin extract in vitro
    • Bagchi D, Garg A, Krohn RL, Bagchi M,Tran MX,Stohs SJ Oxygen free radical scavenging abilities of vitamins C and E, and a grape seed proanthocyanidin extract in vitro. Res Commun Mol Pathol Pharmacol 1997;95: 179-189.
    • (1997) Res Commun Mol Pathol Pharmacol , vol.95 , pp. 179-189
    • Bagchi, D.1    Garg, A.2    Krohn, R.L.3    Bagchi, M.4    Tran, M.X.5    Stohs, S.J.6
  • 18
    • 0025814980 scopus 로고
    • Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes
    • Esterbauer H, Schaur RJ, Zollner H. Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes. Free Radic Biol Med 1991;11: 81-128
    • (1991) Free Radic Biol Med , vol.11 , pp. 81-128
    • Esterbauer, H.1    Schaur, R.J.2    Zollner, H.3
  • 19
    • 0029056083 scopus 로고
    • Health implications of Mediterranean diets in light of contemporary knowledge.1.Plant foods and dairy products
    • Kushi L, Lenart EB, Willet WC. Health implications of Mediterranean diets in light of contemporary knowledge.1.Plant foods and dairy products. Am J Clin Nutr 1995; 61: 1407-1415
    • (1995) Am J Clin Nutr , vol.61 , pp. 1407-1415
    • Kushi, L.1    Lenart, E.B.2    Willet, W.C.3
  • 20
    • 0031884778 scopus 로고    scopus 로고
    • High protection by grape seed proanthocyanidins (GSPC) of poylunsaturated fatty acids against UV.C induced peroxidation
    • Bouhamidi R, Prevost V, Nouvelot A. High protection by grape seed proanthocyanidins (GSPC) of poylunsaturated fatty acids against UV.C induced peroxidation. CR Acad Sci 1998;321: 31-38.
    • (1998) CR Acad Sci , vol.321 , pp. 31-38
    • Bouhamidi, R.1    Prevost, V.2    Nouvelot, A.3
  • 21
    • 0033533593 scopus 로고    scopus 로고
    • Purple grape juice improves endothelial function and reduces the susceptibility of LDL cholesterol to oxidation in patients with coronary artery disease
    • Stein JH, Keevil JG, Wiebe DA,Aeschlimann S,Folts JD. Purple grape juice improves endothelial function and reduces the susceptibility of LDL cholesterol to oxidation in patients with coronary artery disease. Circulation 1999;100: 1050-1055.
    • (1999) Circulation , vol.100 , pp. 1050-1055
    • Stein, J.H.1    Keevil, J.G.2    Wiebe, D.A.3    Aeschlimann, S.4    Folts, J.D.5
  • 22
    • 14644446143 scopus 로고    scopus 로고
    • Bagchi D, Sen CK, Ray SD, et al. Molecular mechanisms of cardioprotection by a novel grape seed proanthocyanidin extract. Mutat Res 2003;523.524: 87-97.
    • Bagchi D, Sen CK, Ray SD, et al. Molecular mechanisms of cardioprotection by a novel grape seed proanthocyanidin extract. Mutat Res 2003;523.524: 87-97.
  • 23
    • 34250647467 scopus 로고    scopus 로고
    • Beneficial effects of grape seed extract on malondialdehyde-modified LDL
    • Sano A, Uchida R, Saito M, et al. Beneficial effects of grape seed extract on malondialdehyde-modified LDL. J Nutr Sci Vitaminol 2007; 53: 174-182.
    • (2007) J Nutr Sci Vitaminol , vol.53 , pp. 174-182
    • Sano, A.1    Uchida, R.2    Saito, M.3
  • 24
    • 2342574954 scopus 로고    scopus 로고
    • Procyanidins from Vitis vinifera seeds display cardioprotection in an experimental model of ischemia-reperfusion damage
    • Berti F, Manfredi B, Mantegazza P, Rossoni G. Procyanidins from Vitis vinifera seeds display cardioprotection in an experimental model of ischemia-reperfusion damage. Drugs Exp Clin Res 2003;29: 207-216.
    • (2003) Drugs Exp Clin Res , vol.29 , pp. 207-216
    • Berti, F.1    Manfredi, B.2    Mantegazza, P.3    Rossoni, G.4
  • 25
    • 18744368815 scopus 로고    scopus 로고
    • Antihypertensive, vasodilator and antioxidant effects of a vinifera grape skin extract
    • Soares De Moura R, Costa Viana FS, Souza MA, et al. Antihypertensive, vasodilator and antioxidant effects of a vinifera grape skin extract. J Pharm Pharmacol 2002; 54: 1515-1520.
    • (2002) J Pharm Pharmacol , vol.54 , pp. 1515-1520
    • Soares De Moura, R.1    Costa Viana, F.S.2    Souza, M.A.3
  • 26
    • 13244258459 scopus 로고    scopus 로고
    • Isolation and structure identification of grape seed polyphenols and its effects on oxidative damage to cellular DNA
    • Fan PH, Lou HX. Isolation and structure identification of grape seed polyphenols and its effects on oxidative damage to cellular DNA. Yao Xue Xue Bao 2004;39: 869-875.
    • (2004) Yao Xue Xue Bao , vol.39 , pp. 869-875
    • Fan, P.H.1    Lou, H.X.2
  • 27
    • 37349091446 scopus 로고    scopus 로고
    • Effect of dietary fat-soluble vitamins A and E and proanthocyanidin-rich extract from grape seeds on oxidative DNA damage in rats
    • Morin B, Narbonne JF, Ribera D,Badouard C,Ravanat JL. Effect of dietary fat-soluble vitamins A and E and proanthocyanidin-rich extract from grape seeds on oxidative DNA damage in rats. Food Chem Toxicol 2008;46: 787-796.
    • (2008) Food Chem Toxicol , vol.46 , pp. 787-796
    • Morin, B.1    Narbonne, J.F.2    Ribera, D.3    Badouard, C.4    Ravanat, J.L.5
  • 28
    • 20744439570 scopus 로고    scopus 로고
    • Grape seed extract suppresses lipid peroxidation and reduces hypoxic ischemic brain injury in neonatal rats
    • Feng Y, Lin YM, Fratkins JD,Le Blanch MH. Grape seed extract suppresses lipid peroxidation and reduces hypoxic ischemic brain injury in neonatal rats. Brain Res Bull 2005;66: 120-127.
    • (2005) Brain Res Bull , vol.66 , pp. 120-127
    • Feng, Y.1    Lin, Y.M.2    Fratkins, J.D.3    Le Blanch, M.H.4
  • 29
    • 31744438823 scopus 로고    scopus 로고
    • Modulatory role of grape seed extract on age-related oxidative DNA damage in central nervous system of rats
    • Balu M, Sangeetha P, Murali G, Panneerselvam C. Modulatory role of grape seed extract on age-related oxidative DNA damage in central nervous system of rats. Brain Res Bull 2006; 68: 469-473.
    • (2006) Brain Res Bull , vol.68 , pp. 469-473
    • Balu, M.1    Sangeetha, P.2    Murali, G.3    Panneerselvam, C.4
  • 30
    • 23744505083 scopus 로고    scopus 로고
    • Age-related oxidative protein damages in central nervous system of rats: Modulatory role of grape seed extract
    • Balu M, Sangeetha P, Muralli G. Age-related oxidative protein damages in central nervous system of rats: modulatory role of grape seed extract. Int J. Dev Neurosci 2005;23: 501-507.
    • (2005) Int J. Dev Neurosci , vol.23 , pp. 501-507
    • Balu, M.1    Sangeetha, P.2    Muralli, G.3
  • 31
    • 33645542656 scopus 로고    scopus 로고
    • Devi SA, Jolitha AB, Ishii N.Grape seed proanthocyanidin extract(GSPE) and antioxidant defense in the brain of adult rats
    • Devi SA, Jolitha AB, Ishii N.Grape seed proanthocyanidin extract(GSPE) and antioxidant defense in the brain of adult rats. Med Sci Monit 2006; 12 : 124-129.
    • (2006) Med Sci Monit , vol.12 , pp. 124-129
  • 32
    • 0037077393 scopus 로고    scopus 로고
    • Yamakoshi J, Saito M, Kataoka S,Tokutake S. Procyanidin rich extract from grape seeds prevents cataract formation in hereditary cataractous (ICR/f) rats
    • Yamakoshi J, Saito M, Kataoka S,Tokutake S. Procyanidin rich extract from grape seeds prevents cataract formation in hereditary cataractous (ICR/f) rats. J Agric Food Chem 2002;50: 4983-4988.
    • (2002) J Agric Food Chem , vol.50 , pp. 4983-4988
  • 33
    • 51549102594 scopus 로고    scopus 로고
    • Multitargeted prevention and therapy of cancer by proanthocyanidins
    • Nandakumar V,Singh T,Katiyar SK.Multitargeted prevention and therapy of cancer by proanthocyanidins. Cancer Lett 2008;269:378-387.
    • (2008) Cancer Lett , vol.269 , pp. 378-387
    • Nandakumar, V.1    Singh, T.2    Katiyar, S.K.3
  • 34
    • 38349000628 scopus 로고    scopus 로고
    • Cancer chemoprevention through dietary antioxidants: Progress and promise
    • Khan N , Afaq F , Mukhtar H . Cancer chemoprevention through dietary antioxidants: progress and promise. Antioxid Redox Signal 2008 ;10: 475-510.
    • (2008) Antioxid Redox Signal , vol.10 , pp. 475-510
    • Khan, N.1    Afaq, F.2    Mukhtar, H.3
  • 35
    • 33745600868 scopus 로고    scopus 로고
    • Ratnam DV, Ankola DD, Bhardwaj V, Sahana DK, Kumar MN. Role of antioxidants in prophylaxis and therapy: a pharmaceutical perspective. J Control Release 2006; 113: 189-207
    • Ratnam DV , Ankola DD , Bhardwaj V , Sahana DK, Kumar MN. Role of antioxidants in prophylaxis and therapy: a pharmaceutical perspective. J Control Release 2006; 113: 189-207.
  • 36
    • 0033847986 scopus 로고    scopus 로고
    • Dietary antioxidants during cancer chemotherapy: Impact on chemotherapeutic effectiveness and development of side effects
    • Conklin KA.Dietary antioxidants during cancer chemotherapy: impact on chemotherapeutic effectiveness and development of side effects. Nutr Can 2000; 37: 1-18.
    • (2000) Nutr Can , vol.37 , pp. 1-18
    • Conklin, K.A.1
  • 37
    • 0034234639 scopus 로고    scopus 로고
    • Oxidative stress interferes with cancer chemotherapy: Inhibition of lymphoma cell apoptosis and phagocytosis
    • Shacter E, Williams J.A, Hinson R.M, Sentürker S,Lee YJ. Oxidative stress interferes with cancer chemotherapy: inhibition of lymphoma cell apoptosis and phagocytosis. Blood 2000;96: 307-313.
    • (2000) Blood , vol.96 , pp. 307-313
    • Shacter, E.1    Williams, J.A.2    Hinson, R.M.3    Sentürker, S.4    Lee, Y.J.5
  • 38
    • 0033538451 scopus 로고    scopus 로고
    • Oxidative stress inhibits apoptosis in human lymphoma cells
    • Lee YJ, Shacter E. Oxidative stress inhibits apoptosis in human lymphoma cells. J Biol Chem 1999;274: 19792-19798.
    • (1999) J Biol Chem , vol.274 , pp. 19792-19798
    • Lee, Y.J.1    Shacter, E.2
  • 39
    • 1842421979 scopus 로고    scopus 로고
    • Protective effect of alpha-tocopherol in head and neck cancer radiation-induced mucositis: A double-blind randomized trial
    • Ferreira PR , Fleck JF , Diehl A , et al . Protective effect of alpha-tocopherol in head and neck cancer radiation-induced mucositis: a double-blind randomized trial. Head Neck 2004 ;26 : 313-321.
    • (2004) Head Neck , vol.26 , pp. 313-321
    • Ferreira, P.R.1    Fleck, J.F.2    Diehl, A.3
  • 40
    • 0036829608 scopus 로고    scopus 로고
    • Mega-dose vitamins and minerals in the treatment of non-metastatic breast cancer: An historicalcohort study
    • Lesperance ML , Olivotto IA , Forde N , et al . Mega-dose vitamins and minerals in the treatment of non-metastatic breast cancer: an historicalcohort study. Breast Cancer Res Treat 2002 ;76 : 137-143.
    • (2002) Breast Cancer Res Treat , vol.76 , pp. 137-143
    • Lesperance, M.L.1    Olivotto, I.A.2    Forde, N.3
  • 41
    • 57349194210 scopus 로고    scopus 로고
    • Role of grape seed extract on methotrexate induced oxidative stress in rat liver
    • Cetin A, Kaynar L, Kocyigit I, et al.Role of grape seed extract on methotrexate induced oxidative stress in rat liver. Am J Chin Med 2008; 36: 861-872.
    • (2008) Am J Chin Med , vol.36 , pp. 861-872
    • Cetin, A.1    Kaynar, L.2    Kocyigit, I.3
  • 42
    • 45849100112 scopus 로고    scopus 로고
    • The effect of grape seed extract on radiation-induced oxidative stres in the rat liver.Turk
    • Cetin A , Kaynar L, Koçyigit I, et al .The effect of grape seed extract on radiation-induced oxidative stres in the rat liver.Turk J Gastroenterol 2008;19: 92-98.
    • (2008) J Gastroenterol , vol.19 , pp. 92-98
    • Cetin, A.1    Kaynar, L.2    Koçyigit, I.3
  • 43
    • 75649102336 scopus 로고    scopus 로고
    • Resveratrol protects against irradiation-induced hepatic and ileal damage via its anti-oxidative activity
    • Velioglu, Ogunc A, Sehirli O, Toklu HZ, Resveratrol protects against irradiation-induced hepatic and ileal damage via its anti-oxidative activity. Free Radic Res 2009 ; 25:1-12.
    • (2009) Free Radic Res , vol.25 , pp. 1-12
    • Velioglu1    Ogunc, A.2    Sehirli, O.3    Toklu, H.Z.4
  • 44
    • 20344378481 scopus 로고    scopus 로고
    • Resveratrol :preventing properties against vascular alterations and ageing
    • Delmas D, Jannin B, Latruffe N. Resveratrol :preventing properties against vascular alterations and ageing. Mol Nutr Food Res 2005; 49: 377-395.
    • (2005) Mol Nutr Food Res , vol.49 , pp. 377-395
    • Delmas, D.1    Jannin, B.2    Latruffe, N.3
  • 46
    • 36049018935 scopus 로고    scopus 로고
    • Protective effects of resveratrol on ethanol-induced apoptosis in embriyonic stem cells and disruption of embryonic development in mouse blastocysts
    • Huang LH, Shiao NH, Hsuuw YD,Chan WH. Protective effects of resveratrol on ethanol-induced apoptosis in embriyonic stem cells and disruption of embryonic development in mouse blastocysts. Toxicology 2007;242: 109-122.
    • (2007) Toxicology , vol.242 , pp. 109-122
    • Huang, L.H.1    Shiao, N.H.2    Hsuuw, Y.D.3    Chan, W.H.4
  • 47
    • 33646068410 scopus 로고    scopus 로고
    • Delmas D,Lancon A,Colin D,Jannin B,Latruffe N.Resveratrol as a chemopreventive agent:a promising molecule for fighting cancer.Curr Drug Targets 2006;7:423-442.
    • Delmas D,Lancon A,Colin D,Jannin B,Latruffe N.Resveratrol as a chemopreventive agent:a promising molecule for fighting cancer.Curr Drug Targets 2006;7:423-442.


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