메뉴 건너뛰기




Volumn 298, Issue 2, 2010, Pages

Endothelin receptors: What's new and what do we need to know?

Author keywords

Functional selectivity; Heterodimerization

Indexed keywords

4 (1,3 BENZODIOXOL 5 YL) 1 [(2,6 DIETHYLPHENYL)CARBAMOYLMETHYL] 2 (4 PROPOXYPHENYL) 3 PYRROLIDINECARBOXYLIC ACID; AMBRISENTAN; ATRASENTAN; DARUSENTAN; ENDOTHELIN A RECEPTOR; ENDOTHELIN A RECEPTOR ANTAGONIST; ENDOTHELIN B RECEPTOR; ENDOTHELIN B RECEPTOR ANTAGONIST; ENDOTHELIN RECEPTOR; IR 2500; IRL 2500; MACITENTAN; N (2,6 DIMETHYLPIPERIDINOCARBONYL) 4 METHYLLEUCYL DEXTRO (1 METHOXYCARBONYLTRYPTOPHANYL) DEXTRO NORLEUCINE; N (3 METHOXY 5 METHYL 2 PYRAZINYL) 2 [4 (1,3,4 OXADIAZOL 2 YL)PHENYL] 3 PYRIDINESULFONAMIDE; RES 7011; SARAFOTOXIN S6C; SITAXSENTAN; SUCCINYLENDOTHELIN 1 [8-21][9 GLUTAMIC ACID 11,15 ALANINE]; UNCLASSIFIED DRUG;

EID: 75449108821     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.00584.2009     Document Type: Review
Times cited : (66)

References (123)
  • 2
    • 25844505574 scopus 로고    scopus 로고
    • 2 receptor heterodimers contribute to angiotensin II hyperresponsiveness in experimental hypertension. J Mol Neurosci 26: 185-192, 2005.
    • 2 receptor heterodimers contribute to angiotensin II hyperresponsiveness in experimental hypertension. J Mol Neurosci 26: 185-192, 2005.
  • 4
    • 33745010011 scopus 로고    scopus 로고
    • Endothelin-1-mediated inflammation in acute renal failure
    • Angerio AD. Endothelin-1-mediated inflammation in acute renal failure. Crit Care Nurs Q 29: 152-156, 2006.
    • (2006) Crit Care Nurs Q , vol.29 , pp. 152-156
    • Angerio, A.D.1
  • 5
    • 0025605345 scopus 로고
    • Cloning and expression of a cDNA encoding an endothelin receptor
    • Arai H, Hori S, Aramori I, Ohkubo H, Nakanishi S. Cloning and expression of a cDNA encoding an endothelin receptor. Nature 348: 730-732, 1990.
    • (1990) Nature , vol.348 , pp. 730-732
    • Arai, H.1    Hori, S.2    Aramori, I.3    Ohkubo, H.4    Nakanishi, S.5
  • 6
    • 3042591642 scopus 로고    scopus 로고
    • Endothelins and the role of endothelin antagonists in the management of posttraumatic vasospasm
    • Armstead WM. Endothelins and the role of endothelin antagonists in the management of posttraumatic vasospasm. Curr Pharm Des 10: 2185-2192, 2004.
    • (2004) Curr Pharm Des , vol.10 , pp. 2185-2192
    • Armstead, W.M.1
  • 9
    • 48849094089 scopus 로고    scopus 로고
    • Yanagisawa Endothelin M. 20 years from discovery to therapy
    • Barton M, Yanagisawa Endothelin M. 20 years from discovery to therapy. Can J Physiol Pharmacol 86: 485-499, 2008.
    • (2008) Can J Physiol Pharmacol , vol.86 , pp. 485-499
    • Barton, M.1
  • 12
    • 34548415037 scopus 로고    scopus 로고
    • The importance of endothelin-1 for vascular dysfunction in cardiovascular disease
    • Bohm F, Pernow J. The importance of endothelin-1 for vascular dysfunction in cardiovascular disease. Cardiovasc Res 76: 8-18, 2007.
    • (2007) Cardiovasc Res , vol.76 , pp. 8-18
    • Bohm, F.1    Pernow, J.2
  • 13
    • 62349112527 scopus 로고    scopus 로고
    • The endothelin system: Evolution of vertebrate-specific ligand-receptor interactions by three rounds of genome duplication
    • Braasch I, Volff JN, Schartl M. The endothelin system: evolution of vertebrate-specific ligand-receptor interactions by three rounds of genome duplication. Mol Biol Evol 26: 783-789, 2009.
    • (2009) Mol Biol Evol , vol.26 , pp. 783-789
    • Braasch, I.1    Volff, J.N.2    Schartl, M.3
  • 14
    • 14644387575 scopus 로고    scopus 로고
    • Emerging role of homo- and heterodimerization in G protein coupled receptor biosynthesis and maturation
    • Bulenger S, Marullo S, Bouvier M. Emerging role of homo- and heterodimerization in G protein coupled receptor biosynthesis and maturation. Trends Pharmacol Sci 26: 131-137, 2005.
    • (2005) Trends Pharmacol Sci , vol.26 , pp. 131-137
    • Bulenger, S.1    Marullo, S.2    Bouvier, M.3
  • 17
    • 47549091368 scopus 로고    scopus 로고
    • Endothelin and its potential role in glaucoma
    • Chauhan BC. Endothelin and its potential role in glaucoma. Can J Ophthalmol 43: 356-360, 2008.
    • (2008) Can J Ophthalmol , vol.43 , pp. 356-360
    • Chauhan, B.C.1
  • 18
    • 0032127619 scopus 로고    scopus 로고
    • The elusive nature of intrinsic efficacy
    • Clarke WP, Bond RA. The elusive nature of intrinsic efficacy. Trends Pharmacol Sci 19: 270-276, 1998.
    • (1998) Trends Pharmacol Sci , vol.19 , pp. 270-276
    • Clarke, W.P.1    Bond, R.A.2
  • 20
    • 0033405442 scopus 로고    scopus 로고
    • Endothelin and post-ganglionic sympathetic neurons
    • Damon DH. Endothelin and post-ganglionic sympathetic neurons. Clin Exp Pharmacol Physiol 26: 1000-1003, 1999.
    • (1999) Clin Exp Pharmacol Physiol , vol.26 , pp. 1000-1003
    • Damon, D.H.1
  • 21
    • 0036266042 scopus 로고    scopus 로고
    • International union of pharmacology. XXIX. Update on endothelin receptor nomenclature
    • Davenport AP. International union of pharmacology. XXIX. Update on endothelin receptor nomenclature. Pharmacol Rev 54: 219-226, 2002.
    • (2002) Pharmacol Rev , vol.54 , pp. 219-226
    • Davenport, A.P.1
  • 23
    • 28844498501 scopus 로고    scopus 로고
    • Endothelin-like peptides
    • Ducancel F. Endothelin-like peptides. Cell Mol Life Sci 62: 2828-2839, 2005.
    • (2005) Cell Mol Life Sci , vol.62 , pp. 2828-2839
    • Ducancel, F.1
  • 25
    • 0034284013 scopus 로고    scopus 로고
    • G-protein coupled receptor dimers in the lime light
    • Devi LA. G-protein coupled receptor dimers in the lime light. Trends Pharmacol Sci 21: 324-329, 2000.
    • (2000) Trends Pharmacol Sci , vol.21 , pp. 324-329
    • Devi, L.A.1
  • 28
    • 46749087878 scopus 로고    scopus 로고
    • Endothelin receptor dimers evaluated by FRET, ligand binding, and calcium mobilization
    • Evans NJ, Walker JW. Endothelin receptor dimers evaluated by FRET, ligand binding, and calcium mobilization. Biophys J 95: 483-492, 2008.
    • (2008) Biophys J , vol.95 , pp. 483-492
    • Evans, N.J.1    Walker, J.W.2
  • 29
    • 48849094291 scopus 로고    scopus 로고
    • 2+ signaling and delayed internalization associated with endothelin receptor heterodimers linked through PDZ finger
    • 2+ signaling and delayed internalization associated with endothelin receptor heterodimers linked through PDZ finger. Can J Physiol Pharmacol 86: 526-535, 2008.
    • (2008) Can J Physiol Pharmacol , vol.86 , pp. 526-535
    • Evans, N.J.1    Walker, J.W.2
  • 30
    • 21744460362 scopus 로고    scopus 로고
    • Endothelin-1 (1-31) is an intermediate in the production of endothelin-1 after big endothelin-1 administration in vivo
    • Fecteau MH, Honore JC, Plante M, Labote J, Rae GA, D'Orleans-Juste Pedro. Endothelin-1 (1-31) is an intermediate in the production of endothelin-1 after big endothelin-1 administration in vivo. Hypertension 46: 87-92, 2005.
    • (2005) Hypertension , vol.46 , pp. 87-92
    • Fecteau, M.H.1    Honore, J.C.2    Plante, M.3    Labote, J.4    Rae, G.A.5    Juste Pedro, D.6
  • 31
    • 34247109991 scopus 로고    scopus 로고
    • Role of endothelins in hypertension
    • Feldstein C, Romero C. Role of endothelins in hypertension. Am J Ther 14: 147-153, 2007.
    • (2007) Am J Ther , vol.14 , pp. 147-153
    • Feldstein, C.1    Romero, C.2
  • 33
    • 0033454061 scopus 로고    scopus 로고
    • Endothelin and the development of the enteric nervous system
    • Gershon MD. Endothelin and the development of the enteric nervous system. Clin Exp Pharmacol Physiol 26: 985-988, 1999.
    • (1999) Clin Exp Pharmacol Physiol , vol.26 , pp. 985-988
    • Gershon, M.D.1
  • 37
    • 34547729187 scopus 로고    scopus 로고
    • Endothelins and hypoxia inducible factor in cancer
    • Grimshaw MJ. Endothelins and hypoxia inducible factor in cancer. Endocr Relat Cancer 14: 233-244, 2007.
    • (2007) Endocr Relat Cancer , vol.14 , pp. 233-244
    • Grimshaw, M.J.1
  • 38
    • 0037303203 scopus 로고    scopus 로고
    • Role of endothelin-1 in osteoblastic bone metastases
    • Guise TA, Yin JJ, Mohammad KS. Role of endothelin-1 in osteoblastic bone metastases. Cancer Suppl 97: 779-784, 2003.
    • (2003) Cancer Suppl , vol.97 , pp. 779-784
    • Guise, T.A.1    Yin, J.J.2    Mohammad, K.S.3
  • 41
    • 39849091784 scopus 로고    scopus 로고
    • Endothelin-1 induced pain and hyperalgesia: A review of pathophysiology, clinical manifestations and future therapeutic options
    • Hans G, Deseure K, Adriaensen H. Endothelin-1 induced pain and hyperalgesia: a review of pathophysiology, clinical manifestations and future therapeutic options. Neuropeptides 42: 119-132, 2008.
    • (2008) Neuropeptides , vol.42 , pp. 119-132
    • Hans, G.1    Deseure, K.2    Adriaensen, H.3
  • 45
    • 28444453290 scopus 로고    scopus 로고
    • Endothelin receptor in gastrointestinal smooth muscle
    • Huang SC. Endothelin receptor in gastrointestinal smooth muscle. Curr Protein Pept Sci 6: 547-557, 2005.
    • (2005) Curr Protein Pept Sci , vol.6 , pp. 547-557
    • Huang, S.C.1
  • 47
    • 67649666989 scopus 로고    scopus 로고
    • Phylogeny, taxonomy, and evolution of the endothelin receptor gene family
    • Hyndman KA, Miyamoto MM, Evans DH. Phylogeny, taxonomy, and evolution of the endothelin receptor gene family. Mol Phylogen Evol 52: 677-687, 2009.
    • (2009) Mol Phylogen Evol , vol.52 , pp. 677-687
    • Hyndman, K.A.1    Miyamoto, M.M.2    Evans, D.H.3
  • 48
    • 0035967883 scopus 로고    scopus 로고
    • An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin
    • Imai Y, Soda M, Inoue H, Hatori N, Mizuno Y, Takahashi R. An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin. Cell 105: 891-902, 2001.
    • (2001) Cell , vol.105 , pp. 891-902
    • Imai, Y.1    Soda, M.2    Inoue, H.3    Hatori, N.4    Mizuno, Y.5    Takahashi, R.6
  • 49
    • 28444465856 scopus 로고    scopus 로고
    • ETA and ETB receptors differentially modulate afferent and efferent arteriolar responses to endothelin
    • Inscho EW, Imig JD, Cook AK, Pollock DM. ETA and ETB receptors differentially modulate afferent and efferent arteriolar responses to endothelin. Br J Pharmacol 146: 1019-1026, 2005.
    • (2005) Br J Pharmacol , vol.146 , pp. 1019-1026
    • Inscho, E.W.1    Imig, J.D.2    Cook, A.K.3    Pollock, D.M.4
  • 50
    • 56849101712 scopus 로고    scopus 로고
    • The importance of endothelin-1 for microvascular dysfunction in diabetes
    • Kalani M. The importance of endothelin-1 for microvascular dysfunction in diabetes. Vas Health Risk Manag 4: 1061-1068, 2008.
    • (2008) Vas Health Risk Manag , vol.4 , pp. 1061-1068
    • Kalani, M.1
  • 51
    • 15244363999 scopus 로고    scopus 로고
    • Sex-specific effects of dual ET-1/ANG II receptor (DEAR) variants in Dahl saltsensitive hypertension rat model
    • Kaneko Y, Herrera VLM, Didishvilli T, Ruiz-Opazo N. Sex-specific effects of dual ET-1/ANG II receptor (DEAR) variants in Dahl saltsensitive hypertension rat model. Physiol Genomics 20: 157-164, 2005.
    • (2005) Physiol Genomics , vol.20 , pp. 157-164
    • Kaneko, Y.1    Herrera, V.L.M.2    Didishvilli, T.3    Ruiz-Opazo, N.4
  • 52
    • 0027301252 scopus 로고
    • Cloning and characterization of an endothelin-3 specific receptor (ETC receptor) from Xenopus laevis dermal melanophores
    • Karne S, Jayawickreme CK, Lerner MR. Cloning and characterization of an endothelin-3 specific receptor (ETC receptor) from Xenopus laevis dermal melanophores. J Biol Chem 268: 19126-19133, 1933.
    • (1933) J Biol Chem , vol.268 , pp. 19126-19133
    • Karne, S.1    Jayawickreme, C.K.2    Lerner, M.R.3
  • 53
    • 36348946976 scopus 로고    scopus 로고
    • Functional selectivity through protean and biased agonism: Who steers the ship?
    • Kenakin T. Functional selectivity through protean and biased agonism: who steers the ship? Mol Pharmacol 72: 1393-1401, 2007.
    • (2007) Mol Pharmacol , vol.72 , pp. 1393-1401
    • Kenakin, T.1
  • 54
    • 34447624153 scopus 로고    scopus 로고
    • Collateral efficacy in drug discovery: Taking advantage of the good (allosteric) nature of 7 TM receptors
    • Kenakin T. Collateral efficacy in drug discovery: taking advantage of the good (allosteric) nature of 7 TM receptors. Trends Pharmacol Sci 28: 407-415, 2007.
    • (2007) Trends Pharmacol Sci , vol.28 , pp. 407-415
    • Kenakin, T.1
  • 55
    • 0038575321 scopus 로고    scopus 로고
    • Endothelins in chronic diabetic complications
    • Khan ZA, Chakrabarti S. Endothelins in chronic diabetic complications. Can J Physiol Pharmacol 81: 622-634, 2003.
    • (2003) Can J Physiol Pharmacol , vol.81 , pp. 622-634
    • Khan, Z.A.1    Chakrabarti, S.2
  • 57
    • 38949153033 scopus 로고    scopus 로고
    • 2+ stores. J Cell Sci 121: 186-195, 2008.
    • 2+ stores. J Cell Sci 121: 186-195, 2008.
  • 58
    • 0029890954 scopus 로고    scopus 로고
    • Endothelins: Renal tubule synthesis and actions
    • Kohan DE. Endothelins: renal tubule synthesis and actions. Clin Exp Pharmacol Physiol 23: 337-344, 1996.
    • (1996) Clin Exp Pharmacol Physiol , vol.23 , pp. 337-344
    • Kohan, D.E.1
  • 59
    • 0027219363 scopus 로고
    • Novel endothelin receptors in the follicular membranes of Xenopus laevis oocytes mediate calcium responses by signal transduction through gap junctions
    • Kumar CS, Nuthulaganti P, Pullen M, Nambi P. Novel endothelin receptors in the follicular membranes of Xenopus laevis oocytes mediate calcium responses by signal transduction through gap junctions. Mol Pharmacol 44: 153-157, 1993.
    • (1993) Mol Pharmacol , vol.44 , pp. 153-157
    • Kumar, C.S.1    Nuthulaganti, P.2    Pullen, M.3    Nambi, P.4
  • 62
    • 33745757778 scopus 로고    scopus 로고
    • The interrelation of the angiotensin and endothelin systems on the modulation of NAD(P)H oxidase
    • Laplante MA, de Champlain J. The interrelation of the angiotensin and endothelin systems on the modulation of NAD(P)H oxidase. Can J Physiol Pharmacol 84: 21-28, 2006.
    • (2006) Can J Physiol Pharmacol , vol.84 , pp. 21-28
    • Laplante, M.A.1    de Champlain, J.2
  • 63
    • 0037625278 scopus 로고    scopus 로고
    • Endothelin-1 in chronic renal failure and hypertension
    • Lariviere R, Lebel M. Endothelin-1 in chronic renal failure and hypertension. Can J Physiol Pharmacol 81: 607-621, 2003.
    • (2003) Can J Physiol Pharmacol , vol.81 , pp. 607-621
    • Lariviere, R.1    Lebel, M.2
  • 65
  • 66
    • 33750502435 scopus 로고    scopus 로고
    • Do orphan G protein coupled receptor have ligand-independent functions? New insights from receptor heterodimers
    • Levoye A, Dam J, Aoub MA, Guillame JL, Jockers R. Do orphan G protein coupled receptor have ligand-independent functions? New insights from receptor heterodimers. EMBO Rep 7: 1094-1098, 2006.
    • (2006) EMBO Rep , vol.7 , pp. 1094-1098
    • Levoye, A.1    Dam, J.2    Aoub, M.A.3    Guillame, J.L.4    Jockers, R.5
  • 68
    • 42049113009 scopus 로고    scopus 로고
    • Endothelins are vascular-derived axonal guidance cues for developing sympathetic neurons
    • Makita T, Sucov HM, Gariepy CE, Yanagisawa M, Ginty DD. Endothelins are vascular-derived axonal guidance cues for developing sympathetic neurons. Nature 452: 759-763, 2008.
    • (2008) Nature , vol.452 , pp. 759-763
    • Makita, T.1    Sucov, H.M.2    Gariepy, C.E.3    Yanagisawa, M.4    Ginty, D.D.5
  • 69
    • 0036193946 scopus 로고    scopus 로고
    • 2+-mobilizing endothelin receptors in C6 gloma cells
    • 2+-mobilizing endothelin receptors in C6 gloma cells. Physiol Res 51: 73-78, 2002.
    • (2002) Physiol Res , vol.51 , pp. 73-78
    • Malik, R.1    Vlasicova, K.2    Sedo, A.3
  • 70
    • 0030248319 scopus 로고    scopus 로고
    • Multiple hepatic functions of endothelin-1: Physiopathological relevance
    • Mallat A, Lotersztajn S. Multiple hepatic functions of endothelin-1: physiopathological relevance. J Hepatol 25: 405-413, 1996.
    • (1996) J Hepatol , vol.25 , pp. 405-413
    • Mallat, A.1    Lotersztajn, S.2
  • 71
    • 0031260186 scopus 로고    scopus 로고
    • Cloning of GPR37, a gene located on chromosome 7 encoding a putative G protein coupled peptide receptor, from a human frontal brain EST library
    • Marazziti D, Golini E, Gallo A, Lombardi MS, Matteoni R, Tocchini-Valentini GP. Cloning of GPR37, a gene located on chromosome 7 encoding a putative G protein coupled peptide receptor, from a human frontal brain EST library. Genomics 45: 68-77, 1997.
    • (1997) Genomics , vol.45 , pp. 68-77
    • Marazziti, D.1    Golini, E.2    Gallo, A.3    Lombardi, M.S.4    Matteoni, R.5    Tocchini-Valentini, G.P.6
  • 72
    • 0035398487 scopus 로고    scopus 로고
    • G-protein-coupled receptors and signaling networks: Emerging paradigms
    • Marinissen JJ, Gutkind JS. G-protein-coupled receptors and signaling networks: emerging paradigms. Trends Pharmacol Sci 22: 368-376, 2001.
    • (2001) Trends Pharmacol Sci , vol.22 , pp. 368-376
    • Marinissen, J.J.1    Gutkind, J.S.2
  • 74
    • 0028183016 scopus 로고
    • International Union of Pharmacology nomenclature of endothelin receptors
    • Masaki T, Vane JR, Vanhoutte PM. International Union of Pharmacology nomenclature of endothelin receptors. Pharmacol Rev 46: 137-142, 1994.
    • (1994) Pharmacol Rev , vol.46 , pp. 137-142
    • Masaki, T.1    Vane, J.R.2    Vanhoutte, P.M.3
  • 75
    • 36249026290 scopus 로고    scopus 로고
    • The ovarian endothelin network: An evolving story
    • Meiden R, Levy N. The ovarian endothelin network: an evolving story. Trends Endocrinol Metab 18: 379-385, 2007.
    • (2007) Trends Endocrinol Metab , vol.18 , pp. 379-385
    • Meiden, R.1    Levy, N.2
  • 78
    • 0030615273 scopus 로고    scopus 로고
    • B receptors in rat isolated small mesenteric arteries
    • B receptors in rat isolated small mesenteric arteries. Br J Pharmacol 120: 1376-1382, 1997.
    • (1997) Br J Pharmacol , vol.120 , pp. 1376-1382
    • Mickley, E.J.1    Gray, G.A.2    Webb, D.J.3
  • 79
    • 33947136255 scopus 로고    scopus 로고
    • Heterodimerization and surface localization of G protein coupled receptor
    • Minneman KP. Heterodimerization and surface localization of G protein coupled receptor. Biochem Pharmacol 73: 1043-1050, 2007.
    • (2007) Biochem Pharmacol , vol.73 , pp. 1043-1050
    • Minneman, K.P.1
  • 82
    • 0033452788 scopus 로고    scopus 로고
    • Endothelin and the central and peripheral nervous systems: A decade of endothelin research
    • Mortensen LH. Endothelin and the central and peripheral nervous systems: a decade of endothelin research. Clin Exp Pharmacol Physiol 26: 980-984, 1999.
    • (1999) Clin Exp Pharmacol Physiol , vol.26 , pp. 980-984
    • Mortensen, L.H.1
  • 83
    • 0033975632 scopus 로고    scopus 로고
    • Endothelin in nasal mucosa: Role in nasal function and inflammation
    • Mullol J, Picado C. Endothelin in nasal mucosa: role in nasal function and inflammation. Clin Exp Allergy 30: 172-177, 2000.
    • (2000) Clin Exp Allergy , vol.30 , pp. 172-177
    • Mullol, J.1    Picado, C.2
  • 86
    • 33746843641 scopus 로고    scopus 로고
    • Endothelin and endothelin receptor antagonism in portopulmonary hypertension
    • Neuhofer W, Gulberg V, Gerbes AL. Endothelin and endothelin receptor antagonism in portopulmonary hypertension. Eur J Clin Invest 36: 54-61, 2006.
    • (2006) Eur J Clin Invest , vol.36 , pp. 54-61
    • Neuhofer, W.1    Gulberg, V.2    Gerbes, A.L.3
  • 87
    • 33746803789 scopus 로고    scopus 로고
    • Role of endothelin and endothelin receptor antagonists in renal disease
    • Neuhofer W, Pittrow D. Role of endothelin and endothelin receptor antagonists in renal disease. Eur J Clin Invest 36: 78-88, 2006.
    • (2006) Eur J Clin Invest , vol.36 , pp. 78-88
    • Neuhofer, W.1    Pittrow, D.2
  • 88
    • 0030035774 scopus 로고    scopus 로고
    • Endothelin receptors: Receptor classification, novel receptor antagonists, and potential therapeutic targets
    • Ohlstein EH, Elliott JD, Feuerstein GZ, Ruffolo RR. Endothelin receptors: receptor classification, novel receptor antagonists, and potential therapeutic targets. Med Res Rev 16: 365-390, 1996.
    • (1996) Med Res Rev , vol.16 , pp. 365-390
    • Ohlstein, E.H.1    Elliott, J.D.2    Feuerstein, G.Z.3    Ruffolo, R.R.4
  • 90
    • 33644638481 scopus 로고    scopus 로고
    • Pharmacological potential of endothelin receptors agonists and antagonists
    • Patocka J, Merka V, Hrdina V, Hrdina R. Pharmacological potential of endothelin receptors agonists and antagonists. Acta Medica 48: 67-73, 2005.
    • (2005) Acta Medica , vol.48 , pp. 67-73
    • Patocka, J.1    Merka, V.2    Hrdina, V.3    Hrdina, R.4
  • 91
    • 0029091082 scopus 로고
    • Endothelin receptors and calcium signaling
    • Pollock DM, Keith TL, Highsmith RF. Endothelin receptors and calcium signaling. FASEB J 9: 1196-1204, 1995.
    • (1995) FASEB J , vol.9 , pp. 1196-1204
    • Pollock, D.M.1    Keith, T.L.2    Highsmith, R.F.3
  • 93
    • 33749020530 scopus 로고    scopus 로고
    • The role of endothelin in chronic renal failure- developments in renal involvement
    • 45: iii36 -iii38
    • Richter CM. The role of endothelin in chronic renal failure- developments in renal involvement. Rheumatology 45: iii36 -iii38, 2006.
    • (2006) Rheumatology
    • Richter, C.M.1
  • 97
    • 0031925707 scopus 로고    scopus 로고
    • Molecular characterization of a dual endothelin-1/angiotensin II receptor
    • Ruiz-Opazo N, Hirayam K, Akimoto K, Herrera VLM. Molecular characterization of a dual endothelin-1/angiotensin II receptor. Mol Med 4: 96-108, 1998.
    • (1998) Mol Med , vol.4 , pp. 96-108
    • Ruiz-Opazo, N.1    Hirayam, K.2    Akimoto, K.3    Herrera, V.L.M.4
  • 98
    • 0034283692 scopus 로고    scopus 로고
    • The human heart endothelin system: ET-1 synthesis, storage, release and effect
    • Russell FD, Molenaar P. The human heart endothelin system: ET-1 synthesis, storage, release and effect. Trends Pharmacol Sci 21: 353-359, 2000.
    • (2000) Trends Pharmacol Sci , vol.21 , pp. 353-359
    • Russell, F.D.1    Molenaar, P.2
  • 99
    • 0025605930 scopus 로고
    • Cloning of a cDNA encoding a non-isopeptide selective subtype of the endothelin receptor
    • Sakurai T, Yanagisawa M, Takuwa Y, Miyazaki H, Kmura S, Goto K, Masaki T. Cloning of a cDNA encoding a non-isopeptide selective subtype of the endothelin receptor. Nature 348: 732-735, 1990.
    • (1990) Nature , vol.348 , pp. 732-735
    • Sakurai, T.1    Yanagisawa, M.2    Takuwa, Y.3    Miyazaki, H.4    Kmura, S.5    Goto, K.6    Masaki, T.7
  • 100
  • 101
    • 33744926908 scopus 로고    scopus 로고
    • Evaluation of endothelin-1-induced pulmonary vasoconstriction following myocardial infarction
    • Sauvageau S, Thorin E, Caron A, Dupuis J. Evaluation of endothelin-1-induced pulmonary vasoconstriction following myocardial infarction. Exp Biol Med (Maywood) 231: 840-846, 2006.
    • (2006) Exp Biol Med (Maywood) , vol.231 , pp. 840-846
    • Sauvageau, S.1    Thorin, E.2    Caron, A.3    Dupuis, J.4
  • 102
    • 34548151315 scopus 로고    scopus 로고
    • Endothelin-1-induced pulmonary vasoreactivity is regulated by ETA and ETB receptor interactions
    • Sauvageau S, Thorin E, Caron A, Dupuis J. Endothelin-1-induced pulmonary vasoreactivity is regulated by ETA and ETB receptor interactions. J Vasc Res 44: 375-381, 2007.
    • (2007) J Vasc Res , vol.44 , pp. 375-381
    • Sauvageau, S.1    Thorin, E.2    Caron, A.3    Dupuis, J.4
  • 103
    • 33645960685 scopus 로고    scopus 로고
    • Pharmacology and physiopathology of the brain endothelin system: An overview
    • Schinelli S. Pharmacology and physiopathology of the brain endothelin system: an overview. Curr Med Chem 13: 627-638, 2006.
    • (2006) Curr Med Chem , vol.13 , pp. 627-638
    • Schinelli, S.1
  • 107
    • 0028609417 scopus 로고
    • Two distinct human endothelin B receptors generated by alternative splicing from a single gene
    • Shyamala V, Moulthrop TH, Stratto-Thomas J, Takamp-Olson P. Two distinct human endothelin B receptors generated by alternative splicing from a single gene. Cell Mol Biol Res 40: 285-296, 1994.
    • (1994) Cell Mol Biol Res , vol.40 , pp. 285-296
    • Shyamala, V.1    Moulthrop, T.H.2    Stratto-Thomas, J.3    Takamp-Olson, P.4
  • 108
    • 33748992287 scopus 로고    scopus 로고
    • The role of endothelin in connective tissue diseases
    • 45: iii8 -iiii10
    • Sticherling M. The role of endothelin in connective tissue diseases. Rheumatology 45: iii8 -iiii10, 2006.
    • (2006) Rheumatology
    • Sticherling, M.1
  • 109
    • 0029560619 scopus 로고
    • Endothelin receptor subtypes and their role in transmembrane signaling mechanisms
    • Sokolvsky M. Endothelin receptor subtypes and their role in transmembrane signaling mechanisms. Pharmacol Ther 68: 435-471, 1995.
    • (1995) Pharmacol Ther , vol.68 , pp. 435-471
    • Sokolvsky, M.1
  • 110
    • 0029557381 scopus 로고
    • Endothelin receptor heterogeneity, G-proteins, and signaling via camp and cGMP cascades
    • Sokolovsky M. Endothelin receptor heterogeneity, G-proteins, and signaling via camp and cGMP cascades. Cell Mol Neurobiol 15: 561-570, 1995.
    • (1995) Cell Mol Neurobiol , vol.15 , pp. 561-570
    • Sokolovsky, M.1
  • 111
    • 1242274647 scopus 로고    scopus 로고
    • 2 vasopressin receptors determines the interaction with beta-arrestin and their trafficking patterns
    • 2 vasopressin receptors determines the interaction with beta-arrestin and their trafficking patterns. Proc Natl Acad Sci USA 101: 1548-1553, 2004.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 1548-1553
    • Terrillon, S.1    Barberis, C.2    Bouvier, M.3
  • 115
    • 34447649922 scopus 로고    scopus 로고
    • β-arrestin-biased ligands at seven-transmembrane receptors
    • Violin JD, Lefkowtiz RJ. β-arrestin-biased ligands at seven-transmembrane receptors. Trends Pharmacol Sci 28: 416-422, 2007.
    • (2007) Trends Pharmacol Sci , vol.28 , pp. 416-422
    • Violin, J.D.1    Lefkowtiz, R.J.2
  • 116
    • 59949098780 scopus 로고    scopus 로고
    • Pathophysiology of the endothelin system-lessons from genetically manipulated animal models
    • Von Websky K, Heiden S, Pfab T, Hocher B. Pathophysiology of the endothelin system-lessons from genetically manipulated animal models. Eur J Med Res 28: 1-6, 2009.
    • (2009) Eur J Med Res , vol.28 , pp. 1-6
    • Von Websky, K.1    Heiden, S.2    Pfab, T.3    Hocher, B.4
  • 118
    • 66249134955 scopus 로고    scopus 로고
    • Serotonylation of vascular proteins important to contraction
    • Watts SW, Priestley JRC, Thompson JM. Serotonylation of vascular proteins important to contraction. PLoS One 4: e5682, 2009.
    • (2009) PLoS One , vol.4
    • Watts, S.W.1    Priestley, J.R.C.2    Thompson, J.M.3
  • 119
    • 0035423590 scopus 로고    scopus 로고
    • Treasures throughout the life-cycle of G protein coupled receptors
    • Wilkie TM. Treasures throughout the life-cycle of G protein coupled receptors. Trends Pharmacol Sci 22: 396-397, 2001.
    • (2001) Trends Pharmacol Sci , vol.22 , pp. 396-397
    • Wilkie, T.M.1
  • 120
    • 33846435175 scopus 로고    scopus 로고
    • Regulation of thromboxane receptor trafficking through the prostacyclin receptor in vascular smooth muscle cells: Role of receptor heterodimerization
    • Wilson SJ, Dowling JK, Zhao L, Carnish E, Smyth EM. Regulation of thromboxane receptor trafficking through the prostacyclin receptor in vascular smooth muscle cells: role of receptor heterodimerization. Arterioscler Thromb Vasc Biol 27: 290-296, 2007.
    • (2007) Arterioscler Thromb Vasc Biol , vol.27 , pp. 290-296
    • Wilson, S.J.1    Dowling, J.K.2    Zhao, L.3    Carnish, E.4    Smyth, E.M.5
  • 123
    • 33847623714 scopus 로고    scopus 로고
    • Receptor dimerization-rationale for the design of bivalent ligands
    • Zhang A, Liu Z, Kan Y. Receptor dimerization-rationale for the design of bivalent ligands. Curr Top Med Chem 7: 3343-345, 2007.
    • (2007) Curr Top Med Chem , vol.7 , pp. 3343-3345
    • Zhang, A.1    Liu, Z.2    Kan, Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.