G-protein-coupled receptor dimers in the lime light

Trends in Pharmacological Sciences

Volumn 21, Issue 9, 2000, Pages 324-326

  Devi, Lakshmi A ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA ADRENERGIC RECEPTOR; G PROTEIN COUPLED RECEPTOR; HYBRID PROTEIN; MEMBRANE RECEPTOR;

BIOLUMINESCENCE; BLEACHING; DIMERIZATION; ENERGY TRANSFER; FLUORESCENCE; MOLECULAR CLONING; MOLECULAR WEIGHT; NOTE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; TECHNIQUE;

EID: 0034284013     PISSN: 01656147     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-6147(00)01519-4     Document Type: Short Survey

References (15)

1. C.H. Heldin Dimerization of cell surface receptors in signal transduction Cell 80 1995 213 223
2. L.E. Limbird R.J. Lefkowtiz Negative cooperativity among β-adrenergic receptors in frog erythrocyte membranes J. Biol. Chem. 251 1976 5007 5014
3. 2 muscarinic receptors Mol. Pharmacol. 39 1991 211 221
4. 2-adrenergic receptor as determined by target size analysis and immunoaffinity chromatography Biochem. Biophys. Res. Commun. 109 1982 21 29
5. S. Avissar Oligomeric structure of muscarinic receptors is shown by photoaffinity labeling: subunit assembly may explain high- and low-affinity agonist states Proc. Natl. Acad. Sci. U. S. A. 80 1983 156 159
6. P.M. Conn Conversion of a gonadotropin-releasing hormone antagonist to an agonist Nature 296 1982 653 655
7. E.E. Hebert M. Bouvier Structural and functional aspects of G-protein coupled receptor oligomerization Biochem. Cell Biol. 76 1998 1 11
8. 2-adrenergic receptor dimerization in living cells using bioluminescence resonance energy transfer (BRET) Proc. Natl. Acad. Sci. U. S. A. 97 2000 3684 3689
9. Y. Xu A bioluminescence resonance energy transfer (BRET) system: application to interacting circadian clock proteins Proc. Natl. Acad. Sci. U. S. A. 96 1999 151 156
10. M.C. Overton K.J. Blumer G-protein-coupled receptors function as oligomers in vivo Curr. Biol. 10 2000 341 344
11. M. Rocheville Subtypes of the somatostatin receptor assemble as functional homo and heterodimers J. Biol. Chem. 275 2000 7862 7869
12. Devi, L.A. et al. G-protein coupled receptor dimerization. J. Mol. Med. (in press)
13. B receptors – the first 7TM heterodimers Trends Pharmacol. Sci. 20 1999 396 399
14. B.A. Jordan L.A. Devi G-protein-coupled receptor hetero-dimerization modulates receptor function Nature 399 1999 697 700
15. M. Rocheville Receptors for dopamine and somatostatin: formation of hetero-oligomers with enhanced functional activity Science 288 2000 154 157