메뉴 건너뛰기




Volumn 29, Issue 11, 2009, Pages 4845-4854

Anti-glioma therapy with temozolomide and status of the DNA-repair gene MGMT

Author keywords

Glioblastoma; O6 methylguanine DNA methyltransferase (MGMT); Review; Temozolomide

Indexed keywords

6 O BENZYLGUANINE; ANTINEOPLASTIC AGENT; BETA INTERFERON; BEVACIZUMAB; CARMUSTINE; CELECOXIB; CISPLATIN; ERLOTINIB; FOTEMUSTINE; HYDROXYUREA; IMATINIB; IRINOTECAN; LOMUSTINE; MARIMASTAT; MESSENGER RNA; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; MITOZOLOMIDE; NIMUSTINE; PROCARBAZINE; PROTEIN P53; TEMOZOLOMIDE; TENIPOSIDE; THALIDOMIDE; VINCRISTINE;

EID: 75149190139     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper
Times cited : (80)

References (105)
  • 1
    • 75149189731 scopus 로고    scopus 로고
    • Kleihues P, Louis DN, Wiestier OD, Burger PC and Scheithauer: WHO grading of tumours of the central nervous system. In: WHO Classification of Tumours of the Central Nervous System, 4th Edition. Louis DN, Ohgaki H and Wiestler OD (eds.). Lyon, International Agency for Research on Cancer, pp. 10-11, 2007.
    • Kleihues P, Louis DN, Wiestier OD, Burger PC and Scheithauer: WHO grading of tumours of the central nervous system. In: WHO Classification of Tumours of the Central Nervous System, 4th Edition. Louis DN, Ohgaki H and Wiestler OD (eds.). Lyon, International Agency for Research on Cancer, pp. 10-11, 2007.
  • 2
    • 0025239917 scopus 로고    scopus 로고
    • Levin VA, Silver P, Hannigan J, Wara WM, Gutin PH, Davis RL abd Wilson CB: Superiority of post-radiotherapy adjuvant chemotherapy with CCNU, procarbazine, and vincristine (PCV) over BCNU for anaplastic gliomas: NCOG 6G61 final report. J Rad One Biol Phys 18: 321-324,1990.
    • Levin VA, Silver P, Hannigan J, Wara WM, Gutin PH, Davis RL abd Wilson CB: Superiority of post-radiotherapy adjuvant chemotherapy with CCNU, procarbazine, and vincristine (PCV) over BCNU for anaplastic gliomas: NCOG 6G61 final report. J Rad One Biol Phys 18: 321-324,1990.
  • 4
    • 0033941733 scopus 로고    scopus 로고
    • Temozolomide and treatment of malignant glioma
    • Friedman HS, Kerby T and Calvert H: Temozolomide and treatment of malignant glioma. Clin Cancer Res 6: 2585-2597, 2000.
    • (2000) Clin Cancer Res , vol.6 , pp. 2585-2597
    • Friedman, H.S.1    Kerby, T.2    Calvert, H.3
  • 7
    • 0029657595 scopus 로고    scopus 로고
    • 6-methylguanine-DNA methyltransferase in resistance of human brain tumor cell lines to the clinically relevant methylating agents temozolomide and streptozotocin
    • 6-methylguanine-DNA methyltransferase in resistance of human brain tumor cell lines to the clinically relevant methylating agents temozolomide and streptozotocin. Clin Cancer Res 2: 735-741, 1996.
    • (1996) Clin Cancer Res , vol.2 , pp. 735-741
    • Bobola, M.S.1    Tseng, S.H.2    Blank, A.3    Berger, M.S.4    Silber, J.R.5
  • 13
    • 0021289188 scopus 로고    scopus 로고
    • Stevens MF, Hickman JA, Stone R, Gibson NW, Baig GU, Lunt E and Newton CG: Antitumor imidazotetrazines. 1. Synthesis and chemistry of 8-carbamoyl-3-(2-chloroethyl)imidazo[5,1-d]-1,2,3,5-tetrazin-4(3 H)-one , a novel broad-spectrum antitumor agent. J Med Chem 27: 196-201, 1984.
    • Stevens MF, Hickman JA, Stone R, Gibson NW, Baig GU, Lunt E and Newton CG: Antitumor imidazotetrazines. 1. Synthesis and chemistry of 8-carbamoyl-3-(2-chloroethyl)imidazo[5,1-d]-1,2,3,5-tetrazin-4(3 H)-one , a novel broad-spectrum antitumor agent. J Med Chem 27: 196-201, 1984.
  • 17
    • 0028956350 scopus 로고
    • Antitumor imidazotetrazines. 32. Synthesis of novel imidazotetrazinones and related bicyclic heterocycles to probe the mode of action of the antitumor drag temozolomide
    • Clark AS, Deans B, Stevens MF, Tisdale MJ, Wheelhouse RT, Denny BJ and Hartley JA: Antitumor imidazotetrazines. 32. Synthesis of novel imidazotetrazinones and related bicyclic heterocycles to probe the mode of action of the antitumor drag temozolomide. J Med Chem 38: 1493-1504,1995.
    • (1995) J Med Chem , vol.38 , pp. 1493-1504
    • Clark, A.S.1    Deans, B.2    Stevens, M.F.3    Tisdale, M.J.4    Wheelhouse, R.T.5    Denny, B.J.6    Hartley, J.A.7
  • 18
    • 0028133013 scopus 로고
    • NMR and molecular modeling investigation of the mechanism of activation of the antitumor drag temozolomide and its interaction with DNA
    • Denny BJ, Wheelhouse RT, Stevens MF, Tsang LL and Slack JA: NMR and molecular modeling investigation of the mechanism of activation of the antitumor drag temozolomide and its interaction with DNA. Biochemistry 33: 9045-9051, 1994.
    • (1994) Biochemistry , vol.33 , pp. 9045-9051
    • Denny, B.J.1    Wheelhouse, R.T.2    Stevens, M.F.3    Tsang, L.L.4    Slack, J.A.5
  • 22
    • 0033557903 scopus 로고    scopus 로고
    • 6-methylguanine-DNA methyltransferase by promoter hypermethylation is a common event in primary human neoplasia
    • 6-methylguanine-DNA methyltransferase by promoter hypermethylation is a common event in primary human neoplasia. Cancer Res 59: 793-797, 1999.
    • (1999) Cancer Res , vol.59 , pp. 793-797
    • Esteller, M.1    Hamilton, S.R.2    Burger, P.C.3    Baylin, S.B.4    Herman, J.G.5
  • 28
    • 0030823671 scopus 로고    scopus 로고
    • 6-methylguanine-DNA methyltransferase gene
    • 6-methylguanine-DNA methyltransferase gene. Cancer Res 57: 3672-3677, 1997.
    • (1997) Cancer Res , vol.57 , pp. 3672-3677
    • Qian, X.C.1    Brent, T.P.2
  • 29
    • 0030874380 scopus 로고    scopus 로고
    • 6-Methylguanine DNA methyltransferase (MGMT) CpG island is associated with heterochromatinization of the MGMT transcription start site and silencing of the gene
    • 6-Methylguanine DNA methyltransferase (MGMT) CpG island is associated with heterochromatinization of the MGMT transcription start site and silencing of the gene. Mol Cell Biol 17: 5612-5619, 1997.
    • (1997) Mol Cell Biol , vol.17 , pp. 5612-5619
    • Watts, G.S.1    Pieper, R.O.2    Costello, J.F.3    Peng, Y.-M.4    Dalton, W.S.5    Futscher, B.W.6
  • 30
    • 0942279488 scopus 로고    scopus 로고
    • 6-methylguanine DNA methyltransferase in human cancer
    • 6-methylguanine DNA methyltransferase in human cancer. Oncogene 23: 1-8, 2004.
    • (2004) Oncogene , vol.23 , pp. 1-8
    • Esteller, M.1    Herman, J.G.2
  • 32
    • 0034795045 scopus 로고    scopus 로고
    • Promoter methylation of the DNA repair gene MGMT in astrocytomas is frequently associated with G:C→A:T mutations of the TP53 tumor suppressor gene
    • Nakamura M, Watanabe T, Yonekawa Y, Kleihues P and Ohgaki H: Promoter methylation of the DNA repair gene MGMT in astrocytomas is frequently associated with G:C→A:T mutations of the TP53 tumor suppressor gene. Carcinogenesis 22: 1715-1719, 2001.
    • (2001) Carcinogenesis , vol.22 , pp. 1715-1719
    • Nakamura, M.1    Watanabe, T.2    Yonekawa, Y.3    Kleihues, P.4    Ohgaki, H.5
  • 33
    • 0035890742 scopus 로고    scopus 로고
    • O(6)- Methylguanine-DNA methyltransferase promoter hypermethylation shifts the p53 mutational spectrum in non-small cell lung cancer
    • Wolf P, Hu YC, Doffek K, Sidransky D and Ahrendt SA: O(6)- Methylguanine-DNA methyltransferase promoter hypermethylation shifts the p53 mutational spectrum in non-small cell lung cancer. Cancer Res 61: 8113-8117, 2001.
    • (2001) Cancer Res , vol.61 , pp. 8113-8117
    • Wolf, P.1    Hu, Y.C.2    Doffek, K.3    Sidransky, D.4    Ahrendt, S.A.5
  • 35
    • 0035575781 scopus 로고    scopus 로고
    • Methylation of O(6)-methylguanine-DNA methyltransferase gene is associated significantly with K-ras mutation, lymph node invasion, tumor staging, and disease-free survival in patients with gastric carcinoma
    • Park TJ, Han SU, Cho YK, Paik WK, Kim YB and Lim IK: Methylation of O(6)-methylguanine-DNA methyltransferase gene is associated significantly with K-ras mutation, lymph node invasion, tumor staging, and disease-free survival in patients with gastric carcinoma. Cancer 92: 2760-2768, 2001.
    • (2001) Cancer , vol.92 , pp. 2760-2768
    • Park, T.J.1    Han, S.U.2    Cho, Y.K.3    Paik, W.K.4    Kim, Y.B.5    Lim, I.K.6
  • 37
    • 0029829167 scopus 로고    scopus 로고
    • Human brain tumor O(6)-methylguanine-DNA methyltransferase mRNA and its significance as an indicator of selective chloroethylnitrosourea chemotherapy
    • Mineura K, Yanagisawa T, Watanabe K, Kowada M and Yasui N: Human brain tumor O(6)-methylguanine-DNA methyltransferase mRNA and its significance as an indicator of selective chloroethylnitrosourea chemotherapy. Int J Cancer 69: 420-425, 1996.
    • (1996) Int J Cancer , vol.69 , pp. 420-425
    • Mineura, K.1    Yanagisawa, T.2    Watanabe, K.3    Kowada, M.4    Yasui, N.5
  • 40
    • 51649117107 scopus 로고    scopus 로고
    • 6-methylguanine methyltransferase (MGMT) promoter methylation with clinical outcomes in glioblastoma and clinical strategies to modulate MGMT activity
    • 6-methylguanine methyltransferase (MGMT) promoter methylation with clinical outcomes in glioblastoma and clinical strategies to modulate MGMT activity. J Clin Oncol 26: 4189-4199, 2008.
    • (2008) J Clin Oncol , vol.26 , pp. 4189-4199
    • Hegi, M.E.1    Liu, L.2    Herman, J.G.3    Stupp, R.4    Wick, W.5    Weiler, M.6    Mehta, M.P.7    Gilbert, M.R.8
  • 43
    • 0031935598 scopus 로고    scopus 로고
    • Practical guidelines for the treatment of malignant gliomas
    • Chamberlain MC and Kormanik PA: Practical guidelines for the treatment of malignant gliomas. West J Med 168: 114-120, 1998.
    • (1998) West J Med , vol.168 , pp. 114-120
    • Chamberlain, M.C.1    Kormanik, P.A.2
  • 44
    • 0023216747 scopus 로고
    • Effect of the extent of surgical resection on survival and quality of life in patients with supratentorial glioblastomas and anaplastic astrocytomas
    • Ammirati M, Vick N, Liao YL, Ciric I and Mikhael M: Effect of the extent of surgical resection on survival and quality of life in patients with supratentorial glioblastomas and anaplastic astrocytomas. Neurosurgery 21: 201-206, 1987.
    • (1987) Neurosurgery , vol.21 , pp. 201-206
    • Ammirati, M.1    Vick, N.2    Liao, Y.L.3    Ciric, I.4    Mikhael, M.5
  • 45
    • 60549111057 scopus 로고    scopus 로고
    • ALA Glioma Study Group: Resection and survival in glioblastoma multiforme: an RTOG recursive partitioning analysis of ALA study patients
    • Pichlmeier U, Bink A, Schackert G and Stummer W; ALA Glioma Study Group: Resection and survival in glioblastoma multiforme: an RTOG recursive partitioning analysis of ALA study patients. Neuro Oncol 10: 1025-1034, 2008.
    • (2008) Neuro Oncol , vol.10 , pp. 1025-1034
    • Pichlmeier, U.1    Bink, A.2    Schackert, G.3    Stummer, W.4
  • 46
    • 33646861578 scopus 로고    scopus 로고
    • Improvement of functional outcome after radical surgery in glioblastoma patients: The efficacy of a navigation-guided fence-post procedure and neurophysiological monitoring
    • Yoshikawa K, Kajiwara K, Morioka J, Fujii M, Tanaka N, Fujisawa H, Kato S, Nomura S and Suzuki M: Improvement of functional outcome after radical surgery in glioblastoma patients: the efficacy of a navigation-guided fence-post procedure and neurophysiological monitoring. J Neurooncol 78: 91-97, 2006.
    • (2006) J Neurooncol , vol.78 , pp. 91-97
    • Yoshikawa, K.1    Kajiwara, K.2    Morioka, J.3    Fujii, M.4    Tanaka, N.5    Fujisawa, H.6    Kato, S.7    Nomura, S.8    Suzuki, M.9
  • 48
    • 0018568970 scopus 로고
    • An analysis of dose-effect relationship in the radiotherapy of malignant gliomas
    • Walker MD, Strike TA and Sheline GE: An analysis of dose-effect relationship in the radiotherapy of malignant gliomas. Int J Radiat Oncol Biol Phys 5: 1725-31, 1979.
    • (1979) Int J Radiat Oncol Biol Phys , vol.5 , pp. 1725-1731
    • Walker, M.D.1    Strike, T.A.2    Sheline, G.E.3
  • 50
    • 49149101331 scopus 로고    scopus 로고
    • EORTC 22972-26991/MRC BRIO trial: Fractionated stereotactic boost following conventional radiotherapy of high grade gliomas. Clinical and quality-assurance results of the stereotactic boost arm
    • Baumert BG, Brada M, Bernier J, Kortmann RD, Dehing-Oberije C, Collette L and Davis JB: EORTC 22972-26991/MRC BRIO trial: fractionated stereotactic boost following conventional radiotherapy of high grade gliomas. Clinical and quality-assurance results of the stereotactic boost arm. Radiother Oncol 88: 163-172, 2008.
    • (2008) Radiother Oncol , vol.88 , pp. 163-172
    • Baumert, B.G.1    Brada, M.2    Bernier, J.3    Kortmann, R.D.4    Dehing-Oberije, C.5    Collette, L.6    Davis, J.B.7
  • 52
    • 0025135063 scopus 로고
    • Procarbazine chemotherapy in the treatment of recurrent malignant astrocytomas after radiation and nitrosourea failure
    • Newton HB, Junck L, Bromberg J, Page MA and Greenberg HS: Procarbazine chemotherapy in the treatment of recurrent malignant astrocytomas after radiation and nitrosourea failure. Neurology 40: 1743-1746, 1990.
    • (1990) Neurology , vol.40 , pp. 1743-1746
    • Newton, H.B.1    Junck, L.2    Bromberg, J.3    Page, M.A.4    Greenberg, H.S.5
  • 53
    • 0026591763 scopus 로고
    • A randomized comparison of intra-arterial versus intravenous BCNU, with or without intravenous 5-fluorouracil, for newly diagnosed patients with malignant glioma
    • Shapiro WR, Green SB, Burger PC, Selker RG, VanGilder JC, Robertson JT, Mealey J Jr, Ransohff J and Mahaley MS Jr: A randomized comparison of intra-arterial versus intravenous BCNU, with or without intravenous 5-fluorouracil, for newly diagnosed patients with malignant glioma. J Neurosurg 76: 772-781, 1992..
    • (1992) J Neurosurg , vol.76 , pp. 772-781
    • Shapiro, W.R.1    Green, S.B.2    Burger, P.C.3    Selker, R.G.4    VanGilder, J.C.5    Robertson, J.T.6    Mealey Jr, J.7    Ransohff, J.8    Mahaley Jr, M.S.9
  • 54
    • 0025239917 scopus 로고    scopus 로고
    • Superiority of post-radiotherapy adjuvant chemotherapy with CCNU, procarbazine, and vincristine (PCV) over BCNU for anaplastic gliomas: NCOG 6G61 final report
    • Levin VA, Silver P, Hannigan J, Wara WM, Gutin PH, Davis RL and Wilson CB: Superiority of post-radiotherapy adjuvant chemotherapy with CCNU, procarbazine, and vincristine (PCV) over BCNU for anaplastic gliomas: NCOG 6G61 final report. Int J Radiat Oncol Biol Phys 18: 321-324, 1990.
    • (1990) Int J Radiat Oncol Biol Phys , vol.18 , pp. 321-324
    • Levin, V.A.1    Silver, P.2    Hannigan, J.3    Wara, W.M.4    Gutin, P.H.5    Davis, R.L.6    Wilson, C.B.7
  • 57
    • 0345270450 scopus 로고    scopus 로고
    • A phase II study of radiotherapy after hyperbaric oxygenation combined with interferon-beta and nimustine hydrochloride to treat supratentorial malignant gliomas
    • Beppu T, Kamada K, Nakamura R, Oikawa H, Takeda M, Fukuda T, Arai H, Ogasawara K and Ogawa A: A phase II study of radiotherapy after hyperbaric oxygenation combined with interferon-beta and nimustine hydrochloride to treat supratentorial malignant gliomas. J Neurooncol 61: 161-170, 2003.
    • (2003) J Neurooncol , vol.61 , pp. 161-170
    • Beppu, T.1    Kamada, K.2    Nakamura, R.3    Oikawa, H.4    Takeda, M.5    Fukuda, T.6    Arai, H.7    Ogasawara, K.8    Ogawa, A.9
  • 58
    • 14644399135 scopus 로고    scopus 로고
    • Human interferon beta, nimustine hydrochloride, and radiation therapy in the treatment of newly diagnosed malignant astrocytomas
    • Watanabe T, Katayama Y, Yoshino A, Fukaya C and Yamamoto T: Human interferon beta, nimustine hydrochloride, and radiation therapy in the treatment of newly diagnosed malignant astrocytomas. J Neurooncol 72: 57-62, 2005.
    • (2005) J Neurooncol , vol.72 , pp. 57-62
    • Watanabe, T.1    Katayama, Y.2    Yoshino, A.3    Fukaya, C.4    Yamamoto, T.5
  • 59
    • 33748454110 scopus 로고    scopus 로고
    • Buckner JC, Ballman KV, Michalak JC, Burton GV, Cascino TL, Schomberg PJ, Hawkins RB, Scheithauer BW, Sandler HM, Marks RS and O' Fallon JR; North Central Cancer Treatment Group 93-72-52; Southwest Oncology Group 9503 Trials: Phase III trial of carmustine and cisplatin compared with carmustine alone and standard radiation therapy or accelerated radiation therapy in patients with glioblastoma multiforme: North Central Cancer Treatment Group 93-72-52 and Southwest Oncology Group 9503 Trials. J Clin Oncol 24: 3871-3879, 2006.
    • Buckner JC, Ballman KV, Michalak JC, Burton GV, Cascino TL, Schomberg PJ, Hawkins RB, Scheithauer BW, Sandler HM, Marks RS and O' Fallon JR; North Central Cancer Treatment Group 93-72-52; Southwest Oncology Group 9503 Trials: Phase III trial of carmustine and cisplatin compared with carmustine alone and standard radiation therapy or accelerated radiation therapy in patients with glioblastoma multiforme: North Central Cancer Treatment Group 93-72-52 and Southwest Oncology Group 9503 Trials. J Clin Oncol 24: 3871-3879, 2006.
  • 60
    • 58949103764 scopus 로고    scopus 로고
    • Prospective trial of gross-total resection with Gliadel wafers followed by early postoperative gamma knife radiosurgery and conformai fractionated radiotherapy as the initial treatment for patients with radiographically suspected, newly diagnosed glioblastoma multiforme
    • Smith KA, Ashby LS, Gonzalez F, Brachman DG, Thomas T, Coons SW, Battaglia M and Scheck A: Prospective trial of gross-total resection with Gliadel wafers followed by early postoperative gamma knife radiosurgery and conformai fractionated radiotherapy as the initial treatment for patients with radiographically suspected, newly diagnosed glioblastoma multiforme. J Neurosurg 109 Suppl: 106-117, 2008.
    • (2008) J Neurosurg , vol.109 , Issue.SUPPL. , pp. 106-117
    • Smith, K.A.1    Ashby, L.S.2    Gonzalez, F.3    Brachman, D.G.4    Thomas, T.5    Coons, S.W.6    Battaglia, M.7    Scheck, A.8
  • 69
    • 33748936494 scopus 로고    scopus 로고
    • Radiation Therapy Oncology Group: Phase II Radiation Therapy Oncology Group trial of conventional radiation therapy followed by treatment with recombinant interferon-beta for supratentorial glioblastoma: results of RTOG 9710
    • Colman H, Berkey BA, Maor MH, Groves MD, Schultz CJ, Vermeulen S, Nelson DF, Mehta MP and Yung WK; Radiation Therapy Oncology Group: Phase II Radiation Therapy Oncology Group trial of conventional radiation therapy followed by treatment with recombinant interferon-beta for supratentorial glioblastoma: results of RTOG 9710. Int J Radiat Oncol Biol Phys 66: 818-824, 2006.
    • (2006) Int J Radiat Oncol Biol Phys , vol.66 , pp. 818-824
    • Colman, H.1    Berkey, B.A.2    Maor, M.H.3    Groves, M.D.4    Schultz, C.J.5    Vermeulen, S.6    Nelson, D.F.7    Mehta, M.P.8    Yung, W.K.9
  • 74
    • 68149169111 scopus 로고    scopus 로고
    • Fotemustine as second-line treatment for recurrent or progressive glioblastoma after concomitant and/or adjuvant temozolomide: A phase II trial of Gruppo Italiano Cooperativo di Neuro-Oncologia (GICNO)
    • in press DOI: 10.1007/s00280-009-0926-8
    • Brandes AA, Tosoni A, Franceschi E, Blatt V, Santoro A, Faedi M, Amistà P, Gardiman M, Labianca R, Bianchini C, Ermani M and Reni M: Fotemustine as second-line treatment for recurrent or progressive glioblastoma after concomitant and/or adjuvant temozolomide: a phase II trial of Gruppo Italiano Cooperativo di Neuro-Oncologia (GICNO). Cancer Chemother Pharmacol, in press (DOI: 10.1007/s00280-009-0926-8)
    • Cancer Chemother Pharmacol
    • Brandes, A.A.1    Tosoni, A.2    Franceschi, E.3    Blatt, V.4    Santoro, A.5    Faedi, M.6    Amistà, P.7    Gardiman, M.8    Labianca, R.9    Bianchini, C.10    Ermani, M.11    Reni, M.12
  • 75
    • 59349113568 scopus 로고    scopus 로고
    • A multi-institutional phase II study on second-line fotemustine chemotherapy in recurrent glioblastoma
    • Fabrini MG, Silvano G, Lolli I, Perrone F, Marsella A, Scotti V and Cionini L: A multi-institutional phase II study on second-line fotemustine chemotherapy in recurrent glioblastoma. J Neurooncol 92: 79-86, 2009.
    • (2009) J Neurooncol , vol.92 , pp. 79-86
    • Fabrini, M.G.1    Silvano, G.2    Lolli, I.3    Perrone, F.4    Marsella, A.5    Scotti, V.6    Cionini, L.7
  • 76
    • 58149470640 scopus 로고    scopus 로고
    • Salvage chemotherapy with bevacizumab for recurrent alkylator-refractory anaplastic astrocytoma
    • Chamberlain MC and Johnston S: Salvage chemotherapy with bevacizumab for recurrent alkylator-refractory anaplastic astrocytoma. J Neurooncol 91: 359-367, 2009.
    • (2009) J Neurooncol , vol.91 , pp. 359-367
    • Chamberlain, M.C.1    Johnston, S.2
  • 78
    • 39749084577 scopus 로고    scopus 로고
    • Multi-institutional phase II study of temozolomide administered twice daily in the treatment of recurrent high-grade gliomas
    • Balmaceda C, Peereboom D, Pannullo S, Cheung YK, Fisher PG, Alavi J, Sisti M, Chen J, Fine RL. Multi-institutional phase II study of temozolomide administered twice daily in the treatment of recurrent high-grade gliomas. Cancer 112: 1139-1146, 2008.
    • (2008) Cancer , vol.112 , pp. 1139-1146
    • Balmaceda, C.1    Peereboom, D.2    Pannullo, S.3    Cheung, Y.K.4    Fisher, P.G.5    Alavi, J.6    Sisti, M.7    Chen, J.8    Fine, R.L.9
  • 80
    • 33750432843 scopus 로고    scopus 로고
    • GICNO: Temozolomide 3 weeks on and 1 week off as first-line therapy for recurrent glioblastoma: phase II study from Grappo Italiano Cooperativo di Neuro-oncologia (GICNO)
    • Brandes AA, Tosoni A, Cavallo G, Bertorelle R, Gioia V, Franceschi E, Biscuola M, Blatt V, Crinò L and Ermani M; GICNO: Temozolomide 3 weeks on and 1 week off as first-line therapy for recurrent glioblastoma: phase II study from Grappo Italiano Cooperativo di Neuro-oncologia (GICNO). Br J Cancer 95: 1155-1160, 2006.
    • (2006) Br J Cancer , vol.95 , pp. 1155-1160
    • Brandes, A.A.1    Tosoni, A.2    Cavallo, G.3    Bertorelle, R.4    Gioia, V.5    Franceschi, E.6    Biscuola, M.7    Blatt, V.8    Crinò, L.9    Ermani, M.10
  • 85
    • 0028026692 scopus 로고
    • Preclinical antitumor activity of temozolomide in mice: Efficacy against human brain tumor xenografts and synergism with 1,3-bis(2-chloroethyl)-1- nitrosourea
    • Plowman J, Waud WR, Koutsoukos AD, Rubinstein LV, Moore TD and Grever MR: Preclinical antitumor activity of temozolomide in mice: efficacy against human brain tumor xenografts and synergism with 1,3-bis(2-chloroethyl)-1- nitrosourea. Cancer Res 54: 3793-3799, 1994.
    • (1994) Cancer Res , vol.54 , pp. 3793-3799
    • Plowman, J.1    Waud, W.R.2    Koutsoukos, A.D.3    Rubinstein, L.V.4    Moore, T.D.5    Grever, M.R.6
  • 87
    • 0030479125 scopus 로고    scopus 로고
    • Mismatch repair mutations override alkyltransferase in conferring resistance to temozolomide but not to 1,3-bis(2-chloroethyl)nitrosourea
    • Liu L, Markowitz S and Gerson SL: Mismatch repair mutations override alkyltransferase in conferring resistance to temozolomide but not to 1,3-bis(2-chloroethyl)nitrosourea. Cancer Res 56: 5375-5379, 1996.
    • (1996) Cancer Res , vol.56 , pp. 5375-5379
    • Liu, L.1    Markowitz, S.2    Gerson, S.L.3
  • 88
    • 0032694518 scopus 로고    scopus 로고
    • Pharmacologic disruption of base excision repair sensitizes mismatch repair-deficient and -proficient colon cancer cells to methylating agents
    • Liu L, Taverna P, Whitacre CM, Chatterjee S and Gerson SL: Pharmacologic disruption of base excision repair sensitizes mismatch repair-deficient and -proficient colon cancer cells to methylating agents. Clin Cancer Res 5: 2908-2917, 1999.
    • (1999) Clin Cancer Res , vol.5 , pp. 2908-2917
    • Liu, L.1    Taverna, P.2    Whitacre, C.M.3    Chatterjee, S.4    Gerson, S.L.5
  • 89
    • 0036793612 scopus 로고    scopus 로고
    • Poly(ADP-ribose) polymerase inhibitor increases growth inhibition and reduces G(2)/M cell accumulation induced by temozolomide in malignant glioma cells
    • Tentori L, Portarena I, Torino F, Scerrati M, Navarra P and Graziani G: Poly(ADP-ribose) polymerase inhibitor increases growth inhibition and reduces G(2)/M cell accumulation induced by temozolomide in malignant glioma cells. Glia 40: 44-54, 2002.
    • (2002) Glia , vol.40 , pp. 44-54
    • Tentori, L.1    Portarena, I.2    Torino, F.3    Scerrati, M.4    Navarra, P.5    Graziani, G.6
  • 91
    • 54049112348 scopus 로고    scopus 로고
    • Replication-dependent radiosensitization of human glioma cells by inhibition of poly(ADP-Ribose) polymerase: Mechanisms and therapeutic potential
    • Dungey FA, Löser DA and Chalmers AJ: Replication-dependent radiosensitization of human glioma cells by inhibition of poly(ADP-Ribose) polymerase: mechanisms and therapeutic potential. Int J Radiat Oncol Biol Phys 72: 1188-1197, 2008.
    • (2008) Int J Radiat Oncol Biol Phys , vol.72 , pp. 1188-1197
    • Dungey, F.A.1    Löser, D.A.2    Chalmers, A.J.3
  • 92
    • 0037085761 scopus 로고    scopus 로고
    • Combined treatment with temozolomide and poly(ADP-ribose) polymerase inhibitor enhances survival of mice bearing hematologic malignancy at the central nervous system site
    • Tentori L, Leonetti C, Scarsella M, d'Amati G, Portarena I, Zupi G, Bonmassar E and Graziani G: Combined treatment with temozolomide and poly(ADP-ribose) polymerase inhibitor enhances survival of mice bearing hematologic malignancy at the central nervous system site. Blood 99: 2241-2224, 2002.
    • (2002) Blood , vol.99 , pp. 2241-2224
    • Tentori, L.1    Leonetti, C.2    Scarsella, M.3    d'Amati, G.4    Portarena, I.5    Zupi, G.6    Bonmassar, E.7    Graziani, G.8
  • 94
    • 60849137218 scopus 로고    scopus 로고
    • Dasatinib-induced autophagy is enhanced in combination with temozolomide in glioma
    • Milano V, Piao Y, LaFortune T and de Groot J: Dasatinib-induced autophagy is enhanced in combination with temozolomide in glioma. Mol Cancer Ther 8: 394-406, 2009.
    • (2009) Mol Cancer Ther , vol.8 , pp. 394-406
    • Milano, V.1    Piao, Y.2    LaFortune, T.3    de Groot, J.4
  • 97
    • 42149132635 scopus 로고    scopus 로고
    • Chemoresistance in gliomas
    • Lu C and Shervington A: Chemoresistance in gliomas. Mol Cell Biochem 312: 71-80, 2008.
    • (2008) Mol Cell Biochem , vol.312 , pp. 71-80
    • Lu, C.1    Shervington, A.2
  • 98
    • 6044221204 scopus 로고    scopus 로고
    • Cancer stem cells in nervous system tumors
    • Singh SK, Clarke ID, Hide T and Dirks PB: Cancer stem cells in nervous system tumors. Oncogene 23: 7267-7273, 2004.
    • (2004) Oncogene , vol.23 , pp. 7267-7273
    • Singh, S.K.1    Clarke, I.D.2    Hide, T.3    Dirks, P.B.4
  • 103
    • 33846695481 scopus 로고    scopus 로고
    • 6- Methylguanine-DNA methyltransferase regulation by p53 in astrocytic cells
    • 6- Methylguanine-DNA methyltransferase regulation by p53 in astrocytic cells. Cancer Res 67: 580-584, 2007.
    • (2007) Cancer Res , vol.67 , pp. 580-584
    • Blough, M.D.1    Zlatescu, M.C.2    Cairncross, J.G.3
  • 105
    • 37549042449 scopus 로고    scopus 로고
    • Differential sensitivity of malignant glioma cells to methylating and chloroethylating anticancer drugs: P53 determines the switch by regulating xpc, ddb2, and DNA double-strand breaks
    • Batista LF, Roos WP, Christmann M, Menck CF and Kaina B: Differential sensitivity of malignant glioma cells to methylating and chloroethylating anticancer drugs: p53 determines the switch by regulating xpc, ddb2, and DNA double-strand breaks. Cancer Res 67: 11886-11895, 2007.
    • (2007) Cancer Res , vol.67 , pp. 11886-11895
    • Batista, L.F.1    Roos, W.P.2    Christmann, M.3    Menck, C.F.4    Kaina, B.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.