메뉴 건너뛰기




Volumn 20, Issue 1, 2009, Pages 175-181

A MDR1 (ABCB1) gene single nucleotide polymorphism predicts outcome of temozolomide treatment in glioblastoma patients

Author keywords

Glioblastoma; MDR1; MGMT; Polymorphism; Temozolomide

Indexed keywords

MESSENGER RNA; METHYL TETRAZOLIUM; MULTIDRUG RESISTANCE PROTEIN 1; TEMOZOLOMIDE; TETRAZOLIUM; UNCLASSIFIED DRUG;

EID: 58949089716     PISSN: 09237534     EISSN: 15698041     Source Type: Journal    
DOI: 10.1093/annonc/mdn548     Document Type: Article
Times cited : (123)

References (30)
  • 1
  • 2
    • 33744913014 scopus 로고    scopus 로고
    • The role of chemotherapy in the treatment of malignant astrocytomas
    • Mathieu D, Fortin D. The role of chemotherapy in the treatment of malignant astrocytomas. Can J Neurol Sci 2006; 33: 127-140.
    • (2006) Can J Neurol Sci , vol.33 , pp. 127-140
    • Mathieu, D.1    Fortin, D.2
  • 3
    • 0030993717 scopus 로고    scopus 로고
    • Temozolomide: A review of its discovery, chemical properties, pre-clinical development and clinical trials
    • Newlands ES, Stevens MF, Wedge SR et al. Temozolomide: A review of its discovery, chemical properties, pre-clinical development and clinical trials. Cancer Treat Rev 1997; 23: 35-61.
    • (1997) Cancer Treat Rev , vol.23 , pp. 35-61
    • Newlands, E.S.1    Stevens, M.F.2    Wedge, S.R.3
  • 4
    • 0035108398 scopus 로고    scopus 로고
    • Multicenter phase II trial of temozolomide in patients with glioblastoma multiforme at first relapse
    • Brada M, Hoang-Xuan K, Rampling R et al. Multicenter phase II trial of temozolomide in patients with glioblastoma multiforme at first relapse. Ann Oncol 2001; 12: 259-266.
    • (2001) Ann Oncol , vol.12 , pp. 259-266
    • Brada, M.1    Hoang-Xuan, K.2    Rampling, R.3
  • 5
    • 0033897173 scopus 로고    scopus 로고
    • A phase II study of temozolomide vs. procarbazine in patients with glioblastoma multiforme at first relapse
    • Yung WK, Albright RE, Olson J et al. A phase II study of temozolomide vs. procarbazine in patients with glioblastoma multiforme at first relapse. Br J Cancer 2000; 83: 588-593.
    • (2000) Br J Cancer , vol.83 , pp. 588-593
    • Yung, W.K.1    Albright, R.E.2    Olson, J.3
  • 6
    • 20044366163 scopus 로고    scopus 로고
    • Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
    • Stupp R, Mason WP, van den Bent MJ et al. Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med 2005; 352: 987-996.
    • (2005) N Engl J Med , vol.352 , pp. 987-996
    • Stupp, R.1    Mason, W.P.2    van den Bent, M.J.3
  • 7
    • 0032435612 scopus 로고    scopus 로고
    • DNA mismatch repair and O6- alkylguanine-DNA alkyltransferase analysis and response to Temodal in newly diagnosed malignant glioma
    • Friedman HS, McLendon RE, Kerby T et al. DNA mismatch repair and O6- alkylguanine-DNA alkyltransferase analysis and response to Temodal in newly diagnosed malignant glioma. J Clin Oncol 1998; 16: 3851-3857.
    • (1998) J Clin Oncol , vol.16 , pp. 3851-3857
    • Friedman, H.S.1    McLendon, R.E.2    Kerby, T.3
  • 8
    • 0034626988 scopus 로고    scopus 로고
    • Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents
    • Esteller M, Garcia-Foncillas J, Andion E et al. Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents. N Engl J Med 2000; 343: 1350-1354.
    • (2000) N Engl J Med , vol.343 , pp. 1350-1354
    • Esteller, M.1    Garcia-Foncillas, J.2    Andion, E.3
  • 9
    • 0033557903 scopus 로고    scopus 로고
    • Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is a common event in primary human neoplasia
    • Esteller M, Hamilton SR, Burger PC et al. Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is a common event in primary human neoplasia. Cancer Res 1999; 59: 793-797.
    • (1999) Cancer Res , vol.59 , pp. 793-797
    • Esteller, M.1    Hamilton, S.R.2    Burger, P.C.3
  • 10
    • 20044372154 scopus 로고    scopus 로고
    • MGMT gene silencing and benefit from temozolomide in glioblastoma
    • Hegi ME, Diserens AC, Gorlia T et al. MGMT gene silencing and benefit from temozolomide in glioblastoma. N Engl J Med 2005; 352: 997-1003.
    • (2005) N Engl J Med , vol.352 , pp. 997-1003
    • Hegi, M.E.1    Diserens, A.C.2    Gorlia, T.3
  • 11
    • 0032900953 scopus 로고    scopus 로고
    • Biochemical, cellular, and pharmacological aspects of the multidrug transporter
    • Ambudkar SV, Dey S, Hrycyna CA et al. Biochemical, cellular, and pharmacological aspects of the multidrug transporter. Annu Rev Pharmacol Toxicol 1999; 39: 361-398.
    • (1999) Annu Rev Pharmacol Toxicol , vol.39 , pp. 361-398
    • Ambudkar, S.V.1    Dey, S.2    Hrycyna, C.A.3
  • 12
    • 0027218689 scopus 로고
    • Biochemistry of multidrug resistance mediated by the multidrug transporter
    • Gottesman MM, Pastan I. Biochemistry of multidrug resistance mediated by the multidrug transporter. Annu Rev Biochem 1993; 62: 385-427.
    • (1993) Annu Rev Biochem , vol.62 , pp. 385-427
    • Gottesman, M.M.1    Pastan, I.2
  • 13
    • 0032861845 scopus 로고    scopus 로고
    • A novel dual function retrovirus expressing multidrug resistance 1 and O6-alkylguanine-DNA-alkyltransferase for engineering resistance of haemopoietic progenitor cells to multiple chemotherapeutic agents
    • Jelinek J, Rafferty JA, Cmejla R et al. A novel dual function retrovirus expressing multidrug resistance 1 and O6-alkylguanine-DNA-alkyltransferase for engineering resistance of haemopoietic progenitor cells to multiple chemotherapeutic agents. Gene Ther 1999; 6: 1489-1493.
    • (1999) Gene Ther , vol.6 , pp. 1489-1493
    • Jelinek, J.1    Rafferty, J.A.2    Cmejla, R.3
  • 14
    • 0035399586 scopus 로고    scopus 로고
    • Expression of multidrug-resistance P-glycoprotein (MDR1) in human brain tumors
    • Demeule M, Shedid D, Beaulieu E et al. Expression of multidrug-resistance P-glycoprotein (MDR1) in human brain tumors. Int J Cancer 2001; 93: 62-66.
    • (2001) Int J Cancer , vol.93 , pp. 62-66
    • Demeule, M.1    Shedid, D.2    Beaulieu, E.3
  • 15
    • 0034724324 scopus 로고    scopus 로고
    • Functional polymorphisms of the human multidrug-resistance gene: Multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo
    • Hoffmeyer S, Burk O, von Richter O et al. Functional polymorphisms of the human multidrug-resistance gene: Multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo. Proc Natl Acad Sci U S A 2000; 97: 3473-3478.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 3473-3478
    • Hoffmeyer, S.1    Burk, O.2    von Richter, O.3
  • 16
    • 0034971274 scopus 로고    scopus 로고
    • The C3435T mutation in the human MDR1 gene is associated with altered efflux of the P-glycoprotein substrate rhodamine 123 from CD56+ natural killer cells
    • Hitzl M, Drescher S, van der KH et al. The C3435T mutation in the human MDR1 gene is associated with altered efflux of the P-glycoprotein substrate rhodamine 123 from CD56+ natural killer cells. Pharmacogenetics 2001; 11: 293-298.
    • (2001) Pharmacogenetics , vol.11 , pp. 293-298
    • Hitzl, M.1    Drescher, S.2    van der, K.H.3
  • 17
    • 3042767682 scopus 로고    scopus 로고
    • Functional implications of genetic polymorphisms in the multidrug resistance gene MDR1 (ABCB1)
    • Pauli-Magnus C, Kroetz DL. Functional implications of genetic polymorphisms in the multidrug resistance gene MDR1 (ABCB1). Pharm Res 2004; 21: 904-913.
    • (2004) Pharm Res , vol.21 , pp. 904-913
    • Pauli-Magnus, C.1    Kroetz, D.L.2
  • 18
    • 0036731995 scopus 로고    scopus 로고
    • MDR1 gene polymorphisms affect therapy outcome in acute myeloid leukemia patients
    • Illmer T, Schuler US, Thiede C et al. MDR1 gene polymorphisms affect therapy outcome in acute myeloid leukemia patients. Cancer Res 2002; 62: 4955-4962.
    • (2002) Cancer Res , vol.62 , pp. 4955-4962
    • Illmer, T.1    Schuler, U.S.2    Thiede, C.3
  • 19
    • 0032980043 scopus 로고    scopus 로고
    • A new PCR MIMIC strategy to quantify low mdr1 mRNA levels in drug resistant cell lines and AML blast samples
    • Illmer T, Schaich M, Oelschlagel U et al. A new PCR MIMIC strategy to quantify low mdr1 mRNA levels in drug resistant cell lines and AML blast samples. Leuk Res 1999; 23: 653-663.
    • (1999) Leuk Res , vol.23 , pp. 653-663
    • Illmer, T.1    Schaich, M.2    Oelschlagel, U.3
  • 20
    • 0025191307 scopus 로고
    • Genomic organization of the human multidrug resistance (MDR1) gene and origin of P-glycoproteins
    • Chen CJ, Clark D, Ueda K et al. Genomic organization of the human multidrug resistance (MDR1) gene and origin of P-glycoproteins. J Biol Chem 1990; 265: 506-514.
    • (1990) J Biol Chem , vol.265 , pp. 506-514
    • Chen, C.J.1    Clark, D.2    Ueda, K.3
  • 21
    • 0035104031 scopus 로고    scopus 로고
    • Frequency of single nucleotide polymorphisms in the P-glycoprotein drug transporter MDR1 gene in white subjects
    • Cascorbi I, Gerloff T, Johne A et al. Frequency of single nucleotide polymorphisms in the P-glycoprotein drug transporter MDR1 gene in white subjects. Clin Pharmacol Ther 2001; 69: 169-174.
    • (2001) Clin Pharmacol Ther , vol.69 , pp. 169-174
    • Cascorbi, I.1    Gerloff, T.2    Johne, A.3
  • 22
    • 0342470476 scopus 로고    scopus 로고
    • Quantitative assessment of retroviral transfer of the human multidrug resistance 1 gene to human mobilized peripheral blood progenitor cells engrafted in nonobese diabetic/severe combined immunodeficient mice
    • Schiedlmeier B, Kuhlcke K, Eckert HG et al. Quantitative assessment of retroviral transfer of the human multidrug resistance 1 gene to human mobilized peripheral blood progenitor cells engrafted in nonobese diabetic/severe combined immunodeficient mice. Blood 2000; 95: 1237-1248.
    • (2000) Blood , vol.95 , pp. 1237-1248
    • Schiedlmeier, B.1    Kuhlcke, K.2    Eckert, H.G.3
  • 23
    • 0033168968 scopus 로고    scopus 로고
    • LightCycler technology for the quantitation of bcr/abl fusion transcripts
    • Kreuzer KA, Lass U, Bohn A et al. LightCycler technology for the quantitation of bcr/abl fusion transcripts. Cancer Res 1999; 59: 3171-3174.
    • (1999) Cancer Res , vol.59 , pp. 3171-3174
    • Kreuzer, K.A.1    Lass, U.2    Bohn, A.3
  • 24
    • 11144349554 scopus 로고    scopus 로고
    • Frequent promoter hypermethylation and low expression of the MGMT gene in oligodendroglial tumors
    • Mollemann M, Wolter M, Felsberg J et al. Frequent promoter hypermethylation and low expression of the MGMT gene in oligodendroglial tumors. Int J Cancer 2005; 113: 379-385.
    • (2005) Int J Cancer , vol.113 , pp. 379-385
    • Mollemann, M.1    Wolter, M.2    Felsberg, J.3
  • 25
    • 0029770135 scopus 로고    scopus 로고
    • MDR1 P-glycoprotein is expressed by endothelial cells of newly formed capillaries in human gliomas but is not expressed in the neovasculature of other primary tumors
    • Toth K, Vaughan MM, Peress NS et al. MDR1 P-glycoprotein is expressed by endothelial cells of newly formed capillaries in human gliomas but is not expressed in the neovasculature of other primary tumors. Am J Pathol 1996; 149: 853-858.
    • (1996) Am J Pathol , vol.149 , pp. 853-858
    • Toth, K.1    Vaughan, M.M.2    Peress, N.S.3
  • 26
    • 0032678857 scopus 로고    scopus 로고
    • Expression of the multidrug-resistance P-glycoprotein (Pgp, MDR-1) by endothelial cells of the neovasculature in central nervous system tumors
    • Sawada T, Kato Y, Sakayori N et al. Expression of the multidrug-resistance P-glycoprotein (Pgp, MDR-1) by endothelial cells of the neovasculature in central nervous system tumors. Brain Tumor Pathol 1999; 16: 23-27.
    • (1999) Brain Tumor Pathol , vol.16 , pp. 23-27
    • Sawada, T.1    Kato, Y.2    Sakayori, N.3
  • 27
    • 3042772026 scopus 로고    scopus 로고
    • Identification of functionally variant MDR1 alleles among European Americans and African Americans
    • Kim RB, Leake BF, Choo EF et al. Identification of functionally variant MDR1 alleles among European Americans and African Americans. Clin Pharmacol Ther 2001; 70: 189-199.
    • (2001) Clin Pharmacol Ther , vol.70 , pp. 189-199
    • Kim, R.B.1    Leake, B.F.2    Choo, E.F.3
  • 28
    • 22544433145 scopus 로고    scopus 로고
    • The C3435T polymorphism of MDR1 and susceptibility to adult glioma
    • Miller KL, Kelsey KT, Wiencke JK et al. The C3435T polymorphism of MDR1 and susceptibility to adult glioma. Neuroepidemiology 2005; 25: 85-90.
    • (2005) Neuroepidemiology , vol.25 , pp. 85-90
    • Miller, K.L.1    Kelsey, K.T.2    Wiencke, J.K.3
  • 29
    • 33846504706 scopus 로고    scopus 로고
    • A "silent" polymorphism in the MDR1 gene changes substrate specificity
    • Kimchi-Sarfaty C, Oh JM, Kim IW et al. A "silent" polymorphism in the MDR1 gene changes substrate specificity. Science 2007; 315: 525-528.
    • (2007) Science , vol.315 , pp. 525-528
    • Kimchi-Sarfaty, C.1    Oh, J.M.2    Kim, I.W.3
  • 30
    • 4444339673 scopus 로고    scopus 로고
    • Molecular mechanisms associated with chromosomal and microsatellite instability in sporadic glioblastoma multiforme
    • Martinez R, Schackert HK, Plaschke J et al. Molecular mechanisms associated with chromosomal and microsatellite instability in sporadic glioblastoma multiforme. Oncology 2004; 66: 395-403.
    • (2004) Oncology , vol.66 , pp. 395-403
    • Martinez, R.1    Schackert, H.K.2    Plaschke, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.