-
2
-
-
33744913014
-
The role of chemotherapy in the treatment of malignant astrocytomas
-
Mathieu D, Fortin D. The role of chemotherapy in the treatment of malignant astrocytomas. Can J Neurol Sci 2006; 33: 127-140.
-
(2006)
Can J Neurol Sci
, vol.33
, pp. 127-140
-
-
Mathieu, D.1
Fortin, D.2
-
3
-
-
0030993717
-
Temozolomide: A review of its discovery, chemical properties, pre-clinical development and clinical trials
-
Newlands ES, Stevens MF, Wedge SR et al. Temozolomide: A review of its discovery, chemical properties, pre-clinical development and clinical trials. Cancer Treat Rev 1997; 23: 35-61.
-
(1997)
Cancer Treat Rev
, vol.23
, pp. 35-61
-
-
Newlands, E.S.1
Stevens, M.F.2
Wedge, S.R.3
-
4
-
-
0035108398
-
Multicenter phase II trial of temozolomide in patients with glioblastoma multiforme at first relapse
-
Brada M, Hoang-Xuan K, Rampling R et al. Multicenter phase II trial of temozolomide in patients with glioblastoma multiforme at first relapse. Ann Oncol 2001; 12: 259-266.
-
(2001)
Ann Oncol
, vol.12
, pp. 259-266
-
-
Brada, M.1
Hoang-Xuan, K.2
Rampling, R.3
-
5
-
-
0033897173
-
A phase II study of temozolomide vs. procarbazine in patients with glioblastoma multiforme at first relapse
-
Yung WK, Albright RE, Olson J et al. A phase II study of temozolomide vs. procarbazine in patients with glioblastoma multiforme at first relapse. Br J Cancer 2000; 83: 588-593.
-
(2000)
Br J Cancer
, vol.83
, pp. 588-593
-
-
Yung, W.K.1
Albright, R.E.2
Olson, J.3
-
6
-
-
20044366163
-
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
-
Stupp R, Mason WP, van den Bent MJ et al. Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med 2005; 352: 987-996.
-
(2005)
N Engl J Med
, vol.352
, pp. 987-996
-
-
Stupp, R.1
Mason, W.P.2
van den Bent, M.J.3
-
7
-
-
0032435612
-
DNA mismatch repair and O6- alkylguanine-DNA alkyltransferase analysis and response to Temodal in newly diagnosed malignant glioma
-
Friedman HS, McLendon RE, Kerby T et al. DNA mismatch repair and O6- alkylguanine-DNA alkyltransferase analysis and response to Temodal in newly diagnosed malignant glioma. J Clin Oncol 1998; 16: 3851-3857.
-
(1998)
J Clin Oncol
, vol.16
, pp. 3851-3857
-
-
Friedman, H.S.1
McLendon, R.E.2
Kerby, T.3
-
8
-
-
0034626988
-
Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents
-
Esteller M, Garcia-Foncillas J, Andion E et al. Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents. N Engl J Med 2000; 343: 1350-1354.
-
(2000)
N Engl J Med
, vol.343
, pp. 1350-1354
-
-
Esteller, M.1
Garcia-Foncillas, J.2
Andion, E.3
-
9
-
-
0033557903
-
Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is a common event in primary human neoplasia
-
Esteller M, Hamilton SR, Burger PC et al. Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is a common event in primary human neoplasia. Cancer Res 1999; 59: 793-797.
-
(1999)
Cancer Res
, vol.59
, pp. 793-797
-
-
Esteller, M.1
Hamilton, S.R.2
Burger, P.C.3
-
10
-
-
20044372154
-
MGMT gene silencing and benefit from temozolomide in glioblastoma
-
Hegi ME, Diserens AC, Gorlia T et al. MGMT gene silencing and benefit from temozolomide in glioblastoma. N Engl J Med 2005; 352: 997-1003.
-
(2005)
N Engl J Med
, vol.352
, pp. 997-1003
-
-
Hegi, M.E.1
Diserens, A.C.2
Gorlia, T.3
-
11
-
-
0032900953
-
Biochemical, cellular, and pharmacological aspects of the multidrug transporter
-
Ambudkar SV, Dey S, Hrycyna CA et al. Biochemical, cellular, and pharmacological aspects of the multidrug transporter. Annu Rev Pharmacol Toxicol 1999; 39: 361-398.
-
(1999)
Annu Rev Pharmacol Toxicol
, vol.39
, pp. 361-398
-
-
Ambudkar, S.V.1
Dey, S.2
Hrycyna, C.A.3
-
12
-
-
0027218689
-
Biochemistry of multidrug resistance mediated by the multidrug transporter
-
Gottesman MM, Pastan I. Biochemistry of multidrug resistance mediated by the multidrug transporter. Annu Rev Biochem 1993; 62: 385-427.
-
(1993)
Annu Rev Biochem
, vol.62
, pp. 385-427
-
-
Gottesman, M.M.1
Pastan, I.2
-
13
-
-
0032861845
-
A novel dual function retrovirus expressing multidrug resistance 1 and O6-alkylguanine-DNA-alkyltransferase for engineering resistance of haemopoietic progenitor cells to multiple chemotherapeutic agents
-
Jelinek J, Rafferty JA, Cmejla R et al. A novel dual function retrovirus expressing multidrug resistance 1 and O6-alkylguanine-DNA-alkyltransferase for engineering resistance of haemopoietic progenitor cells to multiple chemotherapeutic agents. Gene Ther 1999; 6: 1489-1493.
-
(1999)
Gene Ther
, vol.6
, pp. 1489-1493
-
-
Jelinek, J.1
Rafferty, J.A.2
Cmejla, R.3
-
14
-
-
0035399586
-
Expression of multidrug-resistance P-glycoprotein (MDR1) in human brain tumors
-
Demeule M, Shedid D, Beaulieu E et al. Expression of multidrug-resistance P-glycoprotein (MDR1) in human brain tumors. Int J Cancer 2001; 93: 62-66.
-
(2001)
Int J Cancer
, vol.93
, pp. 62-66
-
-
Demeule, M.1
Shedid, D.2
Beaulieu, E.3
-
15
-
-
0034724324
-
Functional polymorphisms of the human multidrug-resistance gene: Multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo
-
Hoffmeyer S, Burk O, von Richter O et al. Functional polymorphisms of the human multidrug-resistance gene: Multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo. Proc Natl Acad Sci U S A 2000; 97: 3473-3478.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 3473-3478
-
-
Hoffmeyer, S.1
Burk, O.2
von Richter, O.3
-
16
-
-
0034971274
-
The C3435T mutation in the human MDR1 gene is associated with altered efflux of the P-glycoprotein substrate rhodamine 123 from CD56+ natural killer cells
-
Hitzl M, Drescher S, van der KH et al. The C3435T mutation in the human MDR1 gene is associated with altered efflux of the P-glycoprotein substrate rhodamine 123 from CD56+ natural killer cells. Pharmacogenetics 2001; 11: 293-298.
-
(2001)
Pharmacogenetics
, vol.11
, pp. 293-298
-
-
Hitzl, M.1
Drescher, S.2
van der, K.H.3
-
17
-
-
3042767682
-
Functional implications of genetic polymorphisms in the multidrug resistance gene MDR1 (ABCB1)
-
Pauli-Magnus C, Kroetz DL. Functional implications of genetic polymorphisms in the multidrug resistance gene MDR1 (ABCB1). Pharm Res 2004; 21: 904-913.
-
(2004)
Pharm Res
, vol.21
, pp. 904-913
-
-
Pauli-Magnus, C.1
Kroetz, D.L.2
-
18
-
-
0036731995
-
MDR1 gene polymorphisms affect therapy outcome in acute myeloid leukemia patients
-
Illmer T, Schuler US, Thiede C et al. MDR1 gene polymorphisms affect therapy outcome in acute myeloid leukemia patients. Cancer Res 2002; 62: 4955-4962.
-
(2002)
Cancer Res
, vol.62
, pp. 4955-4962
-
-
Illmer, T.1
Schuler, U.S.2
Thiede, C.3
-
19
-
-
0032980043
-
A new PCR MIMIC strategy to quantify low mdr1 mRNA levels in drug resistant cell lines and AML blast samples
-
Illmer T, Schaich M, Oelschlagel U et al. A new PCR MIMIC strategy to quantify low mdr1 mRNA levels in drug resistant cell lines and AML blast samples. Leuk Res 1999; 23: 653-663.
-
(1999)
Leuk Res
, vol.23
, pp. 653-663
-
-
Illmer, T.1
Schaich, M.2
Oelschlagel, U.3
-
20
-
-
0025191307
-
Genomic organization of the human multidrug resistance (MDR1) gene and origin of P-glycoproteins
-
Chen CJ, Clark D, Ueda K et al. Genomic organization of the human multidrug resistance (MDR1) gene and origin of P-glycoproteins. J Biol Chem 1990; 265: 506-514.
-
(1990)
J Biol Chem
, vol.265
, pp. 506-514
-
-
Chen, C.J.1
Clark, D.2
Ueda, K.3
-
21
-
-
0035104031
-
Frequency of single nucleotide polymorphisms in the P-glycoprotein drug transporter MDR1 gene in white subjects
-
Cascorbi I, Gerloff T, Johne A et al. Frequency of single nucleotide polymorphisms in the P-glycoprotein drug transporter MDR1 gene in white subjects. Clin Pharmacol Ther 2001; 69: 169-174.
-
(2001)
Clin Pharmacol Ther
, vol.69
, pp. 169-174
-
-
Cascorbi, I.1
Gerloff, T.2
Johne, A.3
-
22
-
-
0342470476
-
Quantitative assessment of retroviral transfer of the human multidrug resistance 1 gene to human mobilized peripheral blood progenitor cells engrafted in nonobese diabetic/severe combined immunodeficient mice
-
Schiedlmeier B, Kuhlcke K, Eckert HG et al. Quantitative assessment of retroviral transfer of the human multidrug resistance 1 gene to human mobilized peripheral blood progenitor cells engrafted in nonobese diabetic/severe combined immunodeficient mice. Blood 2000; 95: 1237-1248.
-
(2000)
Blood
, vol.95
, pp. 1237-1248
-
-
Schiedlmeier, B.1
Kuhlcke, K.2
Eckert, H.G.3
-
23
-
-
0033168968
-
LightCycler technology for the quantitation of bcr/abl fusion transcripts
-
Kreuzer KA, Lass U, Bohn A et al. LightCycler technology for the quantitation of bcr/abl fusion transcripts. Cancer Res 1999; 59: 3171-3174.
-
(1999)
Cancer Res
, vol.59
, pp. 3171-3174
-
-
Kreuzer, K.A.1
Lass, U.2
Bohn, A.3
-
24
-
-
11144349554
-
Frequent promoter hypermethylation and low expression of the MGMT gene in oligodendroglial tumors
-
Mollemann M, Wolter M, Felsberg J et al. Frequent promoter hypermethylation and low expression of the MGMT gene in oligodendroglial tumors. Int J Cancer 2005; 113: 379-385.
-
(2005)
Int J Cancer
, vol.113
, pp. 379-385
-
-
Mollemann, M.1
Wolter, M.2
Felsberg, J.3
-
25
-
-
0029770135
-
MDR1 P-glycoprotein is expressed by endothelial cells of newly formed capillaries in human gliomas but is not expressed in the neovasculature of other primary tumors
-
Toth K, Vaughan MM, Peress NS et al. MDR1 P-glycoprotein is expressed by endothelial cells of newly formed capillaries in human gliomas but is not expressed in the neovasculature of other primary tumors. Am J Pathol 1996; 149: 853-858.
-
(1996)
Am J Pathol
, vol.149
, pp. 853-858
-
-
Toth, K.1
Vaughan, M.M.2
Peress, N.S.3
-
26
-
-
0032678857
-
Expression of the multidrug-resistance P-glycoprotein (Pgp, MDR-1) by endothelial cells of the neovasculature in central nervous system tumors
-
Sawada T, Kato Y, Sakayori N et al. Expression of the multidrug-resistance P-glycoprotein (Pgp, MDR-1) by endothelial cells of the neovasculature in central nervous system tumors. Brain Tumor Pathol 1999; 16: 23-27.
-
(1999)
Brain Tumor Pathol
, vol.16
, pp. 23-27
-
-
Sawada, T.1
Kato, Y.2
Sakayori, N.3
-
27
-
-
3042772026
-
Identification of functionally variant MDR1 alleles among European Americans and African Americans
-
Kim RB, Leake BF, Choo EF et al. Identification of functionally variant MDR1 alleles among European Americans and African Americans. Clin Pharmacol Ther 2001; 70: 189-199.
-
(2001)
Clin Pharmacol Ther
, vol.70
, pp. 189-199
-
-
Kim, R.B.1
Leake, B.F.2
Choo, E.F.3
-
28
-
-
22544433145
-
The C3435T polymorphism of MDR1 and susceptibility to adult glioma
-
Miller KL, Kelsey KT, Wiencke JK et al. The C3435T polymorphism of MDR1 and susceptibility to adult glioma. Neuroepidemiology 2005; 25: 85-90.
-
(2005)
Neuroepidemiology
, vol.25
, pp. 85-90
-
-
Miller, K.L.1
Kelsey, K.T.2
Wiencke, J.K.3
-
29
-
-
33846504706
-
A "silent" polymorphism in the MDR1 gene changes substrate specificity
-
Kimchi-Sarfaty C, Oh JM, Kim IW et al. A "silent" polymorphism in the MDR1 gene changes substrate specificity. Science 2007; 315: 525-528.
-
(2007)
Science
, vol.315
, pp. 525-528
-
-
Kimchi-Sarfaty, C.1
Oh, J.M.2
Kim, I.W.3
-
30
-
-
4444339673
-
Molecular mechanisms associated with chromosomal and microsatellite instability in sporadic glioblastoma multiforme
-
Martinez R, Schackert HK, Plaschke J et al. Molecular mechanisms associated with chromosomal and microsatellite instability in sporadic glioblastoma multiforme. Oncology 2004; 66: 395-403.
-
(2004)
Oncology
, vol.66
, pp. 395-403
-
-
Martinez, R.1
Schackert, H.K.2
Plaschke, J.3
|