Connective tissue growth factor promotes fibrosis downstream of TGFβ and IL-6 in chronic cardiac allograft rejection

American Journal of Transplantation

Volumn 10, Issue 2, 2010, Pages 220-230

  Booth, A J ^a   Csencsits Smith, K ^b   Wood, S C ^a   Lu, G ^a   Lipson, K E ^c   Bishop, D K ^a  

^a UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

^b UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^c FIBROGEN INC   (United States)

Author keywords

Chronic rejection; CTGF; Fibrosis; IL 6; TGF

Indexed keywords

CD4 ANTIBODY; CD40L ANTIBODY; CONNECTIVE TISSUE GROWTH FACTOR; FG 3019; IL 6 ANTIBODY; IMMUNOGLOBULIN G ANTIBODY; IMMUNOSUPPRESSIVE AGENT; INTERLEUKIN 6; MONOCLONAL ANTIBODY; NEUTRALIZING ANTIBODY; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD VESSEL OCCLUSION; CARDIAC GRAFT FIBROSIS; CARDIAC GRAFT REJECTION; CHRONIC GRAFT REJECTION; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE COURSE; FEMALE; FIBROSING ALVEOLITIS; FIBROSIS; GRAFT FAILURE; GRAFT SURVIVAL; HEART TRANSPLANTATION; HEART VENTRICLE HYPERTROPHY; HETEROTOPIC TRANSPLANTATION; IMMUNOSUPPRESSIVE TREATMENT; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REAL TIME POLYMERASE CHAIN REACTION; SURVIVAL RATE;

ANIMALS; ANTIBODIES, NEUTRALIZING; CONNECTIVE TISSUE GROWTH FACTOR; DISEASE PROGRESSION; FEMALE; FIBROSIS; GRAFT SURVIVAL; HEART; HEART TRANSPLANTATION; INTERLEUKIN-6; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; TRANSFORMING GROWTH FACTOR BETA;

EID: 75149132484     PISSN: 16006135     EISSN: 16006143     Source Type: Journal    
DOI: 10.1111/j.1600-6143.2009.02826.x     Document Type: Article

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